The Oncosearch | Oncotarget

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma Research Paper

Celina Ang, Samuel J. Klempner, Siraj M. Ali, Russell Madison, Jeffrey S. Ross, Eric A. Severson, David Fabrizio, Aaron Goodman, Razelle Kurzrock, James Suh, Sherri Z. Millis

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4018-4025

Keywords: immunotherapy, biomarkers, hepatocellular carcinoma, tumor mutation burden

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jun 11, 2019

Keywords: replication stress, common fragile sites, Dicer, genomic instability

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jun 11, 2019

Keywords: replication stress, common fragile sites, Dicer, genomic instability

Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining Research Paper

Dinesh Kumar Barupal, Bei Gao, Jan Budczies, Brett S. Phinney, Bertrand Perroud, Carsten Denkert, Oliver Fiehn

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3894-3909

Keywords: set-enrichment, ChemRICH, multi-omics, metabolic networks, candidate gene prioritization

Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma Research Paper

Teresa Pollicino, Cristina Musolino, Carlo Saitta, Gianluca Tripodi, Marika Lanza, Giuseppina Raffa, Francesca Casuscelli di Tocco, Chiara Raggi, Maria Consiglia Bragazzi, Adalberto Barbera, Giuseppe Navarra, Pietro Invernizzi, Domenico Alvaro, Giovanni Raimondo

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3931-3938

Keywords: hepatitis B virus, covalently closed circular HBV DNA, HBV DNA integration, intrahepatic cholangiocarcinoma, occult HBV Infection

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Richard Glenn C. Delacruz, Imelda T. Sandoval, Kyle Chang, Braden N. Miller, Laura Reyes-Uribe, Ester Borras, Patrick M. Lynch, Melissa W. Taggart, Ernest T. Hawk, Eduardo Vilar, David A. Jones

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3939-3951

Keywords: familial adenomatous polyposis, colon cancer, APC, CNOT3, CtBP1

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Shan-Ju Yeh, Chien-An Chang, Cheng-Wei Li, Lily Hui-Ching Wang, Bor-Sen Chen

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3760-3806

Keywords: lung adenocarcinoma, lung squamous cell carcinoma, NSCLC, genetic and epigenetic network, potential drug target

Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNA Research Paper

Masaki Hanibuchi, Akira Kanoh, Takuya Kuramoto, Tatsuro Saito, Makoto Tobiume, Atsuro Saijo, Hiroyuki Kozai, Mayo Kondo, Shun Morizumi, Hiroto Yoneda, Kozo Kagawa, Hirokazu Ogino, Seidai Sato, Hiroshi Kawano, Kenji Otsuka, Yuko Toyoda, Hiroshi Nokihara, Hisatsugu Goto, Yasuhiko Nishioka

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3654-3666

Keywords: non-small cell lung cancer, circulating free DNA, epidermal growth factor receptor mutation, epidermal growth factor receptor-tyrosine kinase inhibitor

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53 Priority Research Paper

Stephen Tutton, Zhong Deng, Nitish Gulve, Olga Vladimirova, Kate Beishline, Andreas Wiedmer, Maureen Murphy, Paul M. Lieberman

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3581-3591

Keywords: TP53, telomere, TERRA, DNA damage, polymorphism

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

Amit K. Behera, Manoj Kumar, Muthu K. Shanmugam, Aditya Bhattacharya, Vinay J. Rao, Akshay Bhat, Madavan Vasudevan, Kodaganur S. Gopinath, Azeem Mohiyuddin, Anupam Chatterjee, Gautam Sethi, Tapas K. Kundu

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3709-3724

Keywords: oral cancer, oncogene, YY1, CARM1, arginine methylation

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Kathryn Clarke, Christine Young, Fabio Liberante, Mary-Frances McMullin, Alexander Thompson, Ken Mills

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3462-3471

Keywords: HDAC inhibitor, epigenetic, transcriptional regulation, myelodysplastic syndrome (MDS)

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3472-3490

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Jessie Thalmensi, Elodie Pliquet, Christelle Liard, Gabriel Chamel, Christine Kreuz, Thomas Bestetti, Marie Escande, Anna Kostrzak, Anne-Sophie Pailhes-Jimenez, Emmanuèle Bourges, Marion Julithe, Ludovic Bourre, Olivier Keravel, Pascal Clayette, Thierry Huet, Simon Wain-Hobson, Pierre Langlade-Demoyen

Published May 21, 2019 · Vol. 10, No. 36 · pp. 3361-3372

Keywords: DNA vaccine, canine TERT, cancer, immunotherapy, Electro-Gene-Transfer

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Shan-Ju Yeh, Chien-An Chang, Cheng-Wei Li, Lily Hui-Ching Wang, Bor-Sen Chen

Published May 17, 2019

Keywords: lung adenocarcinoma, lung squamous cell carcinoma, NSCLC, genetic and epigenetic network, potential drug target

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Hemayet Ullah, Wangheng Hou, Sivanesan Dakshanamurthy, Qiyi Tang

Published May 14, 2019 · Vol. 10, No. 35 · pp. 3209-3226

Keywords: host targeted antiviral (HTA), herpes simplex virus (HSV), receptor for activated C kinase 1 (RACK1), RACK1 inhibitor, internal ribosomal entry site (IRES)

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Jun Qin, Irfan Shaukat, Didier Mainard, Patrick Netter, Lydia Barré, Mohamed Ouzzine

Published May 7, 2019 · Vol. 10, No. 34 · pp. 3166-3182

Keywords: chondrosarcoma, EGF/EGFR signaling, biomarker, tyrosine kinase inhibitor, cell death

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Al-Balushi MS, Hasson SS, Ali Al Jabri, Paul A McCarron, Murtaza M Tambuwala

Published May 3, 2019

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Al-Balushi MS, Hasson SS, Ali Al Jabri, Paul A McCarron, Murtaza M Tambuwala

Published May 3, 2019

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

A high-throughput screen of pharmacologically active compounds for inhibitors of UHRF1 reveals epigenetic activity of anthracycline derivative chemotherapeutic drugs Research Paper

Hugh Giovinazzo, David Walker, Nicolas Wyhs, Jianyong Liu, David M. Esopi, Ajay M. Vaghasia, Yash Jain, Akshay Bhamidipati, Jianya Zhou, William G. Nelson, Srinivasan Yegnasubramanian

Published Apr 30, 2019 · Vol. 10, No. 32 · pp. 3040-3050

Keywords: DNA methylation, UHRF1 inhibitors, SRA domain, TR-FRET, anthracyclines

P-cadherin mutations are associated with high basal Wnt activity and stemness in canine mammary tumor cell lines Research Paper

Elpetra Timmermans-Sprang, Rob Collin, Arjen Henkes, Meike Philipsen, Jan A. Mol

Published Apr 26, 2019 · Vol. 10, No. 31 · pp. 2930-2946

Keywords: cancer stem cell, canine mammary tumor exome-sequencing, CDH3, Wnt, cSRC

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European Cancer and Oncology Congress

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Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining Research Paper

Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma Research Paper

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNA Research Paper

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53 Priority Research Paper

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

A high-throughput screen of pharmacologically active compounds for inhibitors of UHRF1 reveals epigenetic activity of anthracycline derivative chemotherapeutic drugs Research Paper

P-cadherin mutations are associated with high basal Wnt activity and stemness in canine mammary tumor cell lines Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining Research Paper

Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma Research Paper

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNA Research Paper

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53 Priority Research Paper

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

A DNA telomerase vaccine for canine cancer immunotherapy Research Paper

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification Research Paper

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

A high-throughput screen of pharmacologically active compounds for inhibitors of UHRF1 reveals epigenetic activity of anthracycline derivative chemotherapeutic drugs Research Paper

P-cadherin mutations are associated with high basal Wnt activity and stemness in canine mammary tumor cell lines Research Paper