The Oncosearch | Oncotarget

Glycolytic metabolism influences global chromatin structure Research Paper

Xue-Song Liu, John B. LIttle, Zhi-Min Yuan

Published Jan 13, 2015 · Vol. 6, No. 6 · pp. 4214-4225

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins Research Paper

Raed Rizkallah, Paratchata Batsomboon, Gregory B. Dudley, Myra M. Hurt

Published Jan 13, 2015 · Vol. 6, No. 3 · pp. 1446-1461

Keywords: Kinase, Mitosis, Phosphorylation, C2H2, Zinc Finger Proteins, TOPK/PBK.

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts Research Paper

Zubaidah M. Ramdzan, Ranjana Pal, Simran Kaur, Lam Leduy, Ginette BÃ©rubÃ©, Sayeh Davoudi, Charles Vadnais, Alain Nepveu

Published Jan 8, 2015 · Vol. 6, No. 6 · pp. 3613-3626

TORC2 inhibition may boost DNA-damaging chemotherapy Editorial

Manuel Stucki

Published Jan 7, 2015 · Vol. 6, No. 2 · pp. 586-587

Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma Research Paper

Enrico Derenzini, Claudio Agostinelli, Enrica Imbrogno, Ilaria Iacobucci, Beatrice Casadei, Elisa Brighenti, Simona Righi, Fabio Fuligni, Andrea Ghelli Luserna Di RorÃ, Anna Ferrari, Giovanni Martinelli, Stefano Pileri, Pier Luigi Zinzani

Published Jan 7, 2015 · Vol. 6, No. 9 · pp. 6553-6569

Keywords: Diffuse Large B-cell Lymphoma, genomic instability, CHK1, CHK2, gamma-H2AX, MYC

SWI/SNF complexes are required for full activation of the DNA-damage response Research Paper

Stephanie L. Smith-Roe, Jun Nakamura, Darcy Holley, Paul D. Chastain, Gary B. Rosson, Dennis A. Simpson, John R. Ridpath, David G. Kaufman, William K. Kaufmann, Scott J. Bultman

Published Jan 7, 2015 · Vol. 6, No. 2 · pp. 732-745

Keywords: BRG1, BRM, tumor suppression, DDR, chemotherapeutics

The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression Research Paper

Xiaolu Zhang, Bingnan Li, Nick de Jonge, Magnus BjÃ¶rkholm, Dawei Xu

Published Jan 6, 2015 · Vol. 6, No. 7 · pp. 4888-4900

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis Research Paper

Chuan Bian Lim, Cecilia M. PrÃªle, Svetlana Baltic, Peter G. Arthur, Jenette Creaney, D. Neil Watkins, Philip J. Thompson, Steven E. Mutsaers

Published Jan 3, 2015 · Vol. 6, No. 3 · pp. 1519-1530

Keywords: Apoptosis, mesothelioma, GANT61, Hedgehog, mitochondria, reactive oxygen species

The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis Research Paper

Christophe Chapard, Daniel Hohl, Marcel Huber

Published Jan 2, 2015 · Vol. 6, No. 25 · pp. 20933-20945

HDAC1,2 inhibition impairs EZH2- and BBAP- mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma Research Paper

Danielle P. Johnson, Gabriella S. Spitz, Shweta Tharkar, Steven N. Quayle, Jeffrey R. Shearstone, Simon Jones, Maria E. McDowell, Hannah Wellman, Jessica K. Tyler, Bradley R. Cairns, Mahesh B. Chandrasekharan, Srividya Bhaskara

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4863-4887

p53 activates G₁ checkpoint following DNA damage by doxorubicin during transient mitotic arrest Research Paper

Sun-Yi Hyun, Young-Joo Jang

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4804-4815

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors Research Paper

Sandra Liekens, Sam Noppen, Sofie Gijsbers, Rebecca Sienaert, Roberto Ronca, Chiara Tobia, Marco Presta

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4633-4648

MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation Research Paper

Yuhuang Li, Kishore B Challagundla, Xiao-Xin Sun, Qinghong Zhang, Mu-Shui Dai

Published Dec 31, 2014 · Vol. 6, No. 2 · pp. 1101-1114

Keywords: miR-130a, ribosomal protein, L11, c-Myc, microRNA, miRISC, UV irradiation.

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

Renaud Sabatier, Pascal Finetti, Emilie Mamessier, JosÃ© Adelaide, Max Chaffanet, Hamid Raza Ali, Patrice Viens, Carlos Caldas, Daniel Birnbaum, FranÃ§ois Bertucci

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5449-5464

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1 Research Paper

Kazuyuki Matsushita, Kouichi Kitamura, Bahityar Rahmutulla, Nobuko Tanaka, Takayuki Ishige, Mamoru Satoh, Tyuji Hoshino, Satoru Miyagi, Takeshi Mori, Sakae Itoga, Hideaki Shimada, Takeshi Tomonaga, Minoru Kito, Yaeko Nakajima-Takagi, Shuji Kubo, Chiaki Nakaseko, Masahiko Hatano, Takashi Miki, Masafumi Matsuo, Masaki Fukuyo, Atsushi Kaneda, Atsushi Iwama, Fumio Nomura

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5102-5117

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

Arjun Kalvala, Li Gao, Brittany Aguila, Tyler Reese, Gregory A. Otterson, Miguel A. Villalona-Calero, Wenrui Duan

Published Dec 30, 2014 · Vol. 6, No. 11 · pp. 8777-8787

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Evgeny A. Moskalev, Pouria Jandaghi, Mahdi Fallah, Mehdi Manoochehri, Sandeep K. Botla, Oleg V. Kolychev, Evgeny A. Nikitin, Vladymyr V. Bubnov, M. von Knebel Doeberitz, Oliver Strobel, Thilo Hackert, Markus W. BÃ¼chler, Nathalia Giese, Andrea Bauer, Thomas Muley, Arne Warth, Peter Schirmacher, Florian Haller, JÃ¶rg D. Hoheisel, Yasser Riazalhosseini

Published Dec 30, 2014 · Vol. 6, No. 6 · pp. 4418-4427

Keywords: DNA methylation, Cancer, Diagnosis, GHSR, Epigenetics

Chronic inflammation-related DNA damage response: a driving force of gastric cardia carcinogenesis Research Paper

Runhua Lin, Dejun Xiao, Yi Guo, Dongping Tian, Hailong Yun, Donglin Chen, Min Su

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2856-2864

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas Research Paper

Shun-Fa Yang, Wei-Jiunn Lee, Peng Tan, Chih-Hsin Tang, Michael Hsiao, Feng-Koo Hsieh, Ming-Hsien Chien

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2736-2753

Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma Research Paper

Xijun Liu, Xingwang Zhang, Lingling Ji, Jianxin Gu, Meiling Zhou, She Chen

Published Dec 29, 2014 · Vol. 6, No. 6 · pp. 4226-4238

Keywords: Farnesoid X receptor, Î²-Catenin, TCF4, Hepatocellular carcinoma

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Glycolytic metabolism influences global chromatin structure Research Paper

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins Research Paper

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts Research Paper

TORC2 inhibition may boost DNA-damaging chemotherapy Editorial

Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma Research Paper

SWI/SNF complexes are required for full activation of the DNA-damage response Research Paper

The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression Research Paper

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis Research Paper

The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis Research Paper

HDAC1,2 inhibition impairs EZH2- and BBAP- mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma Research Paper

p53 activates G₁ checkpoint following DNA damage by doxorubicin during transient mitotic arrest Research Paper

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors Research Paper

MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation Research Paper

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1 Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Chronic inflammation-related DNA damage response: a driving force of gastric cardia carcinogenesis Research Paper

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas Research Paper

Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Glycolytic metabolism influences global chromatin structure Research Paper

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins Research Paper

The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts Research Paper

TORC2 inhibition may boost DNA-damaging chemotherapy Editorial

Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma Research Paper

SWI/SNF complexes are required for full activation of the DNA-damage response Research Paper

The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression Research Paper

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis Research Paper

The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis Research Paper

HDAC1,2 inhibition impairs EZH2- and BBAP- mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma Research Paper

p53 activates G1 checkpoint following DNA damage by doxorubicin during transient mitotic arrest Research Paper

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors Research Paper

MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation Research Paper

Prognostic and predictive value of PDL1 expression in breast cancer Clinical Research Papers

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1 Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers Clinical Research Papers

Chronic inflammation-related DNA damage response: a driving force of gastric cardia carcinogenesis Research Paper

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas Research Paper

Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma Research Paper

p53 activates G₁ checkpoint following DNA damage by doxorubicin during transient mitotic arrest Research Paper