The Oncosearch | Oncotarget

3â€™-Phosphoadenosine 5â€™-phosphosulfate synthase 1 (PAPSS1) knockdown sensitizes non-small cell lung cancer cells to DNA damaging agents Research Paper

Ada W. Y. Leung, Wieslawa H. Dragowska, Daniel Ricaurte, Brian Kwok, Veena Mathew, Jeroen Roosendaal, Amith Ahluwalia, Corinna Warburton, Janessa J. Laskin, Peter C. Stirling, Mohammed A. Qadir, Marcel B. Bally

Published Apr 11, 2015 · Vol. 6, No. 19 · pp. 17161-17177

Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase Research Paper

Ke Li, Jun Pang, Huaiyan Cheng, Wei-Peng Liu, Jin-Ming Di, Heng-Jun Xiao, Yun Luo, Hao Zhang, Wen-Tao Huang, Ming-Kun Chen, Liao-Yuan Li, Chun-Kui Shao, Ying-Hong Feng, Xin Gao

Published Apr 9, 2015 · Vol. 6, No. 12 · pp. 10030-10044

Expression alterations define unique molecular characteristics of spinal ependymomas Research Paper

Anbarasu Lourdusamy, Ruman Rahman, Richard G. Grundy

Published Mar 30, 2015 · Vol. 6, No. 23 · pp. 19780-19791

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair Research Paper

Upadhyayula Sai Srinivas, Jerzy Dyczkowski, Tim BeiÃŸbarth, Jochen Gaedcke, Wael Y. Mansour, Kerstin Borgmann, Matthias Dobbelstein

Published Mar 30, 2015 · Vol. 6, No. 14 · pp. 12574-12586

Enhanced tumorigenicity by mitochondrial DNA mild mutations Research Paper

Alberto Cruz-BermÃºdez, Carmen G. Vallejo, Ramiro J. Vicente-Blanco, MarÃa Esther Gallardo, Miguel Ãngel FernÃ¡ndez-Moreno, Miguel Quintanilla, Rafael Garesse

Published Mar 30, 2015 · Vol. 6, No. 15 · pp. 13628-13643

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma Clinical Research Papers

Qian Mei, Meixia Chen, Xuechun Lu, Xiang Li, Feng Duan, Maoqiang Wang, Guangbin Luo, Weidong Han

Published Mar 29, 2015 · Vol. 6, No. 18 · pp. 16698-16711

Dual targeting of microtubule and topoisomerase II by Î±-carboline derivative YCH337 for tumor proliferation and growth inhibition Research Paper

Jun-Mei Yi, Xiao-Fei Zhang, Xia-Juan Huan, Shan-Shan Song, Wei Wang, Qian-Ting Tian, Yi-Ming Sun, Yi Chen, Jian Ding, Ying-Qing Wang, Chun-Hao Yang, Ze-Hong Miao

Published Mar 27, 2015 · Vol. 6, No. 11 · pp. 8960-8973

Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis Research Paper

Lindsay A. Bonsignore, Jill Sergesketter Butler, Carolyn M. Klinge, Christine E. Schaner Tooley

Published Mar 26, 2015 · Vol. 6, No. 14 · pp. 12248-12263

Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets Research Paper

Sujana Movva, Wenhsiang Wen, Wangjuh Chen, Sherri Z. Millis, Zoran Gatalica, Sandeep Reddy, Margaret von Mehren, Brian A. Van Tine

Published Mar 26, 2015 · Vol. 6, No. 14 · pp. 12234-12247

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Filip Janku, Philipp Angenendt, Apostolia M. Tsimberidou, Siqing Fu, Aung Naing, Gerald S. Falchook, David S. Hong, Veronica R. Holley, Goran Cabrilo, Jennifer J. Wheler, Sarina A. Piha-Paul, Ralph G. Zinner, Agop Y. Bedikian, Michael J. Overman, Bryan K. Kee, Kevin B. Kim, Scott E. Kopetz, Rajyalakshmi Luthra, Frank Diehl, Funda Meric-Bernstam, Razelle Kurzrock

Published Mar 25, 2015 · Vol. 6, No. 14 · pp. 12809-12821

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Laura R. H. Ip, George Poulogiannis, Felipe Cia Viciano, Junko Sasaki, Satoshi Kofuji, Victoria J. Spanswick, Daniel Hochhauser, John A. Hartley, Takehiko Sasaki, Christina A. Gewinner

Published Mar 24, 2015 · Vol. 6, No. 12 · pp. 10548-10562

Autoimmune response to PARP and BRCA1/BRCA2 in cancer Research Paper

Qing Zhu, Su-Xia Han, Cong-Ya Zhou, Meng-Jiao Cai, Li-Ping Dai, Jian-Ying Zhang

Published Mar 24, 2015 · Vol. 6, No. 13 · pp. 11575-11584

A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging Research Paper

Marianne Schauer, Tina Kottek, Madeleine SchÃ¶nherr, Animesh Bhattacharya, Saleh M. Ibrahim, Misa Hirose, RÃ¼diger KÃ¶hling, Georg Fuellen, Ulf Schmitz, Manfred Kunz

Published Mar 24, 2015 · Vol. 6, No. 11 · pp. 8552-8566

Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU Research Paper

Xin Li, Jie Yu, Malcolm V. Brock, Qian Tao, James G. Herman, Ping Liang, Mingzhou Guo

Published Mar 21, 2015 · Vol. 6, No. 13 · pp. 11547-11560

Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2â€™-deoxycytidine in human leukemic KG1 cells Research Paper

StÃ©phane VispÃ©, Arthur Deroide, Emeline Davoine, CÃ©cile Desjobert, Fabrice Lestienne, Lucie Fournier, Natacha Novosad, Sophie BrÃ©and, JÃ©rÃ´me Besse, Florence Busato, JÃ¶rg Tost, Luc De Vries, Didier Cussac, JoÃ«lle Riond, Paola B. Arimondo

Published Mar 20, 2015 · Vol. 6, No. 17 · pp. 15265-15282

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity Priority Research Paper

Jessica Frankum, Pavel Moudry, Rachel Brough, Zdenek Hodny, Alan Ashworth, Jiri Bartek, Christopher J. Lord

Published Mar 18, 2015 · Vol. 6, No. 13 · pp. 10746-10758

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

Andreas D. Ã˜rskov, Marianne B. Treppendahl, Anni Skovbo, Mette S. Holm, Lone S. Friis, Marianne Hokland, Kirsten GrÃ¸nbÃ¦k

Published Mar 18, 2015 · Vol. 6, No. 11 · pp. 9612-9626

Combination of carbon ion beam and gemcitabine causes irreparable DNA damage and death of radioresistant pancreatic cancer stem-like cells in vitro and in vivo Research Perspective

Sei Sai, Toshifumi Wakai, Guillaume Vares, Shigeru Yamada, Takehiko Kamijo, Tadashi Kamada, Toshiyuki Shirai

Published Mar 14, 2015 · Vol. 6, No. 8 · pp. 5517-5535

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis Research Paper

Evgeniy Stoyanov, Guy Ludwig, Lina Mizrahi, Devorah Olam, Temima Schnitzer-Perlman, Elena Tasika, Gabriele Sass, Gisa Tiegs, Yong Jiang, Ting Nie, James Kohler, Raymond F. Schinazi, Paula M. Vertino, Howard Cedar, Eithan Galun, Daniel Goldenberg

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11047-11060

E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells Research Paper

Minghui Wu, Edward Seto, Jingsong Zhang

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11252-11263

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3â€™-Phosphoadenosine 5â€™-phosphosulfate synthase 1 (PAPSS1) knockdown sensitizes non-small cell lung cancer cells to DNA damaging agents Research Paper

Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase Research Paper

Expression alterations define unique molecular characteristics of spinal ependymomas Research Paper

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair Research Paper

Enhanced tumorigenicity by mitochondrial DNA mild mutations Research Paper

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma Clinical Research Papers

Dual targeting of microtubule and topoisomerase II by Î±-carboline derivative YCH337 for tumor proliferation and growth inhibition Research Paper

Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis Research Paper

Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets Research Paper

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Autoimmune response to PARP and BRCA1/BRCA2 in cancer Research Paper

A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging Research Paper

Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU Research Paper

Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2â€™-deoxycytidine in human leukemic KG1 cells Research Paper

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity Priority Research Paper

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

Combination of carbon ion beam and gemcitabine causes irreparable DNA damage and death of radioresistant pancreatic cancer stem-like cells in vitro and in vivo Research Perspective

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis Research Paper

E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

3â€™-Phosphoadenosine 5â€™-phosphosulfate synthase 1 (PAPSS1) knockdown sensitizes non-small cell lung cancer cells to DNA damaging agents Research Paper

Manipulation of prostate cancer metastasis by locus-specific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase Research Paper

Expression alterations define unique molecular characteristics of spinal ependymomas Research Paper

5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair Research Paper

Enhanced tumorigenicity by mitochondrial DNA mild mutations Research Paper

An open-label, single-arm, phase I/II study of lower-dose decitabine based therapy in patients with advanced hepatocellular carcinoma Clinical Research Papers

Dual targeting of microtubule and topoisomerase II by Î±-carboline derivative YCH337 for tumor proliferation and growth inhibition Research Paper

Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis Research Paper

Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets Research Paper

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies Clinical Research Papers

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment Research Paper

Autoimmune response to PARP and BRCA1/BRCA2 in cancer Research Paper

A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging Research Paper

Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU Research Paper

Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2â€™-deoxycytidine in human leukemic KG1 cells Research Paper

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity Priority Research Paper

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

Combination of carbon ion beam and gemcitabine causes irreparable DNA damage and death of radioresistant pancreatic cancer stem-like cells in vitro and in vivo Research Perspective

Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis Research Paper

E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells Research Paper