The Oncosearch | Oncotarget

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion Priority Research Paper

Huabo Wang, Lokendra Sharma, Jie Lu, Paul Finch, Steven Fletcher, Edward V. Prochownik

Published May 30, 2015 · Vol. 6, No. 18 · pp. 15857-15870

The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin Research Paper

JosÃ© Luis OrdÃ³Ã±ez, Ana Teresa Amaral, Angel M. Carcaboso, David Herrero-MartÃn, MarÃa del Carmen GarcÃa-MacÃas, Vicky Sevillano, Diego Alonso, Guillem Pascual-Pasto, Laura San-Segundo, Monica Vila-Ubach, Telmo Rodrigues, Susana Fraile, Cristina Teodosio, AgustÃn Mayo-Iscar, Miguel Aracil, Carlos MarÃa Galmarini, Oscar M. Tirado, Jaume Mora, Enrique de Ãlava

Published May 27, 2015 · Vol. 6, No. 22 · pp. 18875-18890

Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery Clinical Research Papers

Shin Yup Lee, Mi Jeong Hong, Hyo-Sung Jeon, Yi Young Choi, Jin Eun Choi, Hyo-Gyoung Kang, Deuk Kju Jung, Chengcheng Jin, Sook Kyung Do, Seung Soo Yoo, Yangki Seok, Eung Bae Lee, Kyung Min Shin, Ji Yun Jeong, Won Kee Lee, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Young Tae Kim, Sanghoon Jheon, Jae Yong Park

Published May 27, 2015 · Vol. 6, No. 27 · pp. 24522-24532

Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism Research Paper

Stefano J. Mandriota, Linda J. Valentijn, Laurence Lesne, David R. Betts, Denis Marino, Mary Boudal-Khoshbeen, Wendy B. London, Anne-Laure Rougemont, Edward F. Attiyeh, John M. Maris, Michael D. Hogarty, Jan Koster, Jan J. Molenaar, Rogier Versteeg, Marc Ansari, Fabienne Gumy-Pause

Published May 26, 2015 · Vol. 6, No. 21 · pp. 18558-18576

Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib Research Paper

Kazuko Sakai, Haruhiko Takeda, Norihiro Nishijima, Etsuro Orito, Kouji Joko, Yasushi Uchida, Namiki Izumi, Kazuto Nishio, Yukio Osaki

Published May 25, 2015 · Vol. 6, No. 25 · pp. 21636-21644

PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes Research Paper

Yng-Tay Chen, Wei-De Lin, Wen-Lin Liao, Ying-Ju Lin, Jan-Gowth Chang, Fuu-Jen Tsai

Published May 25, 2015 · Vol. 6, No. 15 · pp. 12997-13005

Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic Research Paper

Zhuang Miao, Lin Wu, Ming Lu, Xianzhi Meng, Bo Gao, Xin Qiao, Weihui Zhang, Dongbo Xue

Published May 25, 2015 · Vol. 6, No. 25 · pp. 21493-21506

Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened Review

Annelies Gonnissen, Sofie Isebaert, Karin Haustermans

Published May 22, 2015 · Vol. 6, No. 16 · pp. 13899-13913

Radiosensitization and downregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K) upon inhibition of mitogen/extracellular signal-regulated kinase (MEK) in malignant melanoma cells Research Paper

Stefan Eder, Andreas Lamkowski, Markus Priller, Matthias Port, Konrad Steinestel

Published May 22, 2015 · Vol. 6, No. 19 · pp. 17178-17191

TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer Research Paper

Wen-bin Liu, Fei Han, Xiao Jiang, Hong-qiang Chen, Huan Zhao, Yong Liu, Yong-hong Li, Chuanshu Huang, Jia Cao, Jin-yi Liu

Published May 22, 2015 · Vol. 6, No. 25 · pp. 21225-21239

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer Research Paper

Yu-Ching Wen, Wei-Jiunn Lee, Peng Tan, Shun-Fa Yang, Michael Hsiao, Liang-Ming Lee, Ming-Hsien Chien

Published May 22, 2015 · Vol. 6, No. 25 · pp. 21120-21136

Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells Research Paper

Joyce P.Y. Mak, Wing Yu Man, Jeremy P.H. Chow, Hoi Tang Ma, Randy Y.C. Poon

Published May 21, 2015 · Vol. 6, No. 25 · pp. 21074-21084

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development Research Paper

Qingyang Gu, Bin Zhang, Hongye Sun, Qiang Xu, Yexiong Tan, Guan Wang, Qin Luo, Weiguo Xu, Shuqun Yang, Jian Li, Jing Fu, Lei Chen, Shengxian Yuan, Guibai Liang, Qunsheng Ji, Shu-Hui Chen, Chi-Chung Chan, Weiping Zhou, Xiaowei Xu, Hongyang Wang, Douglas D. Fang

Published May 21, 2015 · Vol. 6, No. 24 · pp. 20160-20176

DNA methylation and cognitive aging Review

Xiangru Xu

Published May 20, 2015 · Vol. 6, No. 16 · pp. 13922-13932

Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition Research Paper

Md. Asaduzzaman Khan, Mousumi Tania, Chunli Wei, Zhiqiang Mei, Shelly Fu, Jingliang Cheng, Jianming Xu, Junjiang Fu

Published May 19, 2015 · Vol. 6, No. 23 · pp. 19580-19591

Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21^WAF1, Cdt1 and the p12 subunit of DNA polymerase Î´ revealed in individual cells by cytometry Review

Zbigniew Darzynkiewicz, Hong Zhao, Sufang Zhang, Marietta Y.W.T. Lee, Ernest Y.C. Lee, Zhongtao Zhang

Published May 15, 2015 · Vol. 6, No. 14 · pp. 11735-11750

miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma Research Paper

Luqing Zhao, Min Tang, Zheyu Hu, Bin Yan, Weiwei Pi, Zhi Li, Jing Zhang, Liqin Zhang, Wuzhong Jiang, Guo Li, Yuanzheng Qiu, Fang Hu, Feng Liu, Jingchen Lu, Xue Chen, Lanbo Xiao, Zhijie Xu, Yongguang Tao, Lifang Yang, Ann M. Bode, Zigang Dong, Jian Zhou, Jia Fan, Lunquan Sun, Ya Cao

Published May 14, 2015 · Vol. 6, No. 18 · pp. 15995-16018

Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression Research Paper

Haolong Li, Ning Xie, Martin E. Gleave, Xuesen Dong

Published May 12, 2015 · Vol. 6, No. 24 · pp. 20474-20484

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers Research Paper

Yihang Shen, Yuan-Hao Lee, Jayabal Panneerselvam, Jun Zhang, Lenora W. M. Loo, Peiwen Fei

Published May 9, 2015 · Vol. 6, No. 24 · pp. 20396-20403

Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment Research Paper

Samuel Seoane, Efigenia Arias, Rita Sigueiro, Juan Sendon-Lago, Anxo Martinez-OrdoÃ±ez, Esteban Castelao, NoemÃ EirÃ³, TomÃ¡s Garcia-Caballero, Manuel Macia, Rafael Lopez-Lopez, Miguel Maestro, Francisco Vizoso, Antonio MouriÃ±o, Roman Perez-Fernandez

Published May 8, 2015 · Vol. 6, No. 16 · pp. 14456-14471

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Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion Priority Research Paper

The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin Research Paper

Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery Clinical Research Papers

Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism Research Paper

Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib Research Paper

PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes Research Paper

Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic Research Paper

Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened Review

Radiosensitization and downregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K) upon inhibition of mitogen/extracellular signal-regulated kinase (MEK) in malignant melanoma cells Research Paper

TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer Research Paper

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer Research Paper

Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells Research Paper

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development Research Paper

DNA methylation and cognitive aging Review

Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition Research Paper

Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21^WAF1, Cdt1 and the p12 subunit of DNA polymerase Î´ revealed in individual cells by cytometry Review

miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma Research Paper

Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression Research Paper

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers Research Paper

Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion Priority Research Paper

The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin Research Paper

Functional intronic ERCC1 polymorphism from regulomeDB can predict survival in lung cancer after surgery Clinical Research Papers

Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism Research Paper

Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib Research Paper

PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes Research Paper

Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic Research Paper

Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened Review

Radiosensitization and downregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K) upon inhibition of mitogen/extracellular signal-regulated kinase (MEK) in malignant melanoma cells Research Paper

TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer Research Paper

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer Research Paper

Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells Research Paper

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development Research Paper

DNA methylation and cognitive aging Review

Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition Research Paper

Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase Î´ revealed in individual cells by cytometry Review

miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma Research Paper

Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression Research Paper

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers Research Paper

Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment Research Paper

Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21^WAF1, Cdt1 and the p12 subunit of DNA polymerase Î´ revealed in individual cells by cytometry Review