The Oncosearch | Oncotarget

Mutational profiling of colorectal cancers with microsatellite instability Research Paper

Elaine I. Lin, Li-Hui Tseng, Christopher D. Gocke, Stacy Reil, Dung T. Le, Nilofer S. Azad, James R. Eshleman

Published Oct 16, 2015 · Vol. 6, No. 39 · pp. 42334-42344

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide Research Paper

Roger Ramcharan, Tamara Aleksic, Wilfride Petnga Kamdoum, Shan Gao, Sophia X. Pfister, Jordan Tanner, Esther Bridges, Ruth Asher, Amanda J. Watson, Geoffrey P. Margison, Mick Woodcock, Emmanouela Repapi, Ji-Liang Li, Mark R. Middleton, Valentine M. Macaulay

Published Oct 15, 2015 · Vol. 6, No. 37 · pp. 39877-39890

Overexpression of Mcl-1 confers resistance to BRAF^V600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper

Neel M. Fofaria, Dennie T. Frederick, Ryan J. Sullivan, Keith T. Flaherty, Sanjay K. Srivastava

Published Oct 14, 2015 · Vol. 6, No. 38 · pp. 40535-40556

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients Research Paper

Rui Wang, Yang Zhang, Yunjian Pan, Yuan Li, Haichuan Hu, Deng Cai, Hang Li, Ting Ye, Xiaoyang Luo, Yiliang Zhang, Bin Li, Lei Shen, Yihua Sun, Haiquan Chen

Published Oct 12, 2015 · Vol. 6, No. 33 · pp. 34300-34308

Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1 Research Paper

Zongwei Gao, Qingjuan Shang, Zhaoyun Liu, Chun Deng, Chunbao Guo

Published Oct 9, 2015 · Vol. 6, No. 34 · pp. 36338-36353

Effects of a novel Nodal-targeting monoclonal antibody in melanoma Priority Research Paper

Luigi Strizzi, Annamaria Sandomenico, Naira V. Margaryan, Annalia FocÃ, Luca Sanguigno, Thomas M. Bodenstine, Grace S. Chandler, David W. Reed, Alina Gilgur, Elisabeth A. Seftor, Richard E.B. Seftor, Zhila Khalkhali-Ellis, Antonio Leonardi, Menotti Ruvo, Mary J.C. Hendrix

Published Oct 9, 2015 · Vol. 6, No. 33 · pp. 34071-34086

Biomarker-based prognostic stratification of young adult glioblastoma Clinical Research Papers

Rui-qi Zhang, Zhifeng Shi, Hong Chen, Nellie Yuk-Fei Chung, Zi Yin, Kay Ka-Wai Li, Danny Tat-Ming Chan, Wai Sang Poon, Jinsong Wu, Liangfu Zhou, Aden Ka-yin Chan, Ying Mao, Ho-Keung Ng

Published Oct 5, 2015 · Vol. 7, No. 4 · pp. 5030-5041

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts Research Paper

Christopher H. Lieu, Peter J. Klauck, Patrick K. Henthorn, John J. Tentler, Aik-Choon Tan, Anna Spreafico, Heather M. Selby, Blair C. Britt, Stacey M. Bagby, John J. Arcaroli, Wells A. Messersmith, Todd M. Pitts, S. Gail Eckhardt

Published Oct 1, 2015 · Vol. 6, No. 33 · pp. 34561-34572

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway Research Paper

Rajmohan Murali, Raghu Chandramohan, Inga MÃ¶ller, Simone L. Scholz, Michael Berger, Kety Huberman, Agnes Viale, Mono Pirun, Nicholas D. Socci, Nancy Bouvier, Sebastian Bauer, Monika Artl, Bastian Schilling, Tobias Schimming, Antje Sucker, Benjamin Schwindenhammer, Florian Grabellus, Michael R. Speicher, JÃ¶rg Schaller, Uwe Hillen, Dirk Schadendorf, Thomas Mentzel, Donavan T. Cheng, Thomas Wiesner, Klaus G. Griewank

Published Sep 30, 2015 · Vol. 6, No. 34 · pp. 36041-36052

What links BRAF to the heart function? new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment Review

Enrico Bronte, Giuseppe Bronte, Giuseppina Novo, Fabrizio Bronte, Maria Grazia Bavetta, Giuseppe Lo Re, Giuseppe Brancatelli, Viviana Bazan, Clara Natoli, Salvatore Novo, Antonio Russo

Published Sep 28, 2015 · Vol. 6, No. 34 · pp. 35589-35601

LGR5 is associated with tumor aggressiveness in papillary thyroid cancer Research Paper

Gregory Michelotti, Xiaoyin Jiang, Julie Ann Sosa, Anna Mae Diehl, Brittany Bohinc Henderson

Published Sep 25, 2015 · Vol. 6, No. 33 · pp. 34549-34560

Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma Research Paper

Elin S. Gray, Helen Rizos, Anna L. Reid, Suzanah C. Boyd, Michelle R. Pereira, Johnny Lo, Varsha Tembe, James Freeman, Jenny H.J. Lee, Richard A. Scolyer, Kelvin Siew, Chris Lomma, Adam Cooper, Muhammad A. Khattak, Tarek M. Meniawy, Georgina V. Long, Matteo S. Carlino, Michael Millward, Melanie Ziman

Published Sep 22, 2015 · Vol. 6, No. 39 · pp. 42008-42018

A constitutive active MAPK/ERK pathway due to BRAF^V600E positively regulates AHR pathway in PTC Research Paper

Gianluca Occhi, Susi Barollo, Daniela Regazzo, Loris Bertazza, Francesca Galuppini, Vincenza Guzzardo, Marie Lise Jaffrain-Rea, Federica Vianello, Denis Ciato, Filippo Ceccato, Sara Watutantrige-Fernando, Andrea Bisognin, Stefania Bortoluzzi, Gianmaria Pennelli, Marco Boscaro, Carla Scaroni, Caterina Mian

Published Sep 16, 2015 · Vol. 6, No. 31 · pp. 32104-32114

Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age Research Paper

Adam M. Fontebasso, Margret Shirinian, Dong-Anh Khuong-Quang, Denise Bechet, Tenzin Gayden, Marcel Kool, Nicolas De Jay, Karine Jacob, Noha Gerges, Barbara Hutter, Huriye Åžeker-Cin, Hendrik Witt, Alexandre Montpetit, SÃ©bastien Brunet, Pierre Lepage, GeneviÃ¨ve Bourret, Almos Klekner, LÃ¡szlÃ³ BognÃ¡r, Peter Hauser, MiklÃ³s Garami, Jean-Pierre Farmer, Jose-Luis Montes, Jeffrey Atkinson, Sally Lambert, Tony Kwan, Andrey Korshunov, Uri Tabori, V. Peter Collins, Steffen Albrecht, Damien Faury, Stefan M. Pfister, Werner Paulus, Martin Hasselblatt, David T.W. Jones, Nada Jabado

Published Sep 10, 2015 · Vol. 6, No. 31 · pp. 31844-31856

Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin Research Paper

Aparna Lakshmanan, Daniel Scarberry, Jill A. Green, Xiaoli Zhang, Samia Selmi-Ruby, Sissy M. Jhiang

Published Sep 9, 2015 · Vol. 6, No. 31 · pp. 31792-31804

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics Research Paper

Gilda Magliacane, Greta Grassini, Paola Bartocci, Ilaria Francaviglia, Elena Dal Cin, Gianluca Barbieri, Gianluigi Arrigoni, Lorenza Pecciarini, Claudio Doglioni, Maria Giulia Cangi

Published Sep 2, 2015 · Vol. 6, No. 31 · pp. 30592-30603

Disulfiram anti-cancer efficacy without copper overload is enhanced by extracellular H₂O₂ generation: antagonism by tetrathiomolybdate Research Paper

Ali Calderon-Aparicio, Mary Strasberg-Rieber, Manuel Rieber

Published Aug 7, 2015 · Vol. 6, No. 30 · pp. 29771-29781

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells Research Paper

Harish Chandra Pal, Ronald D. Baxter, Katherine M. Hunt, Jyoti Agarwal, Craig A. Elmets, Mohammad Athar, Farrukh Afaq

Published Jul 31, 2015 · Vol. 6, No. 29 · pp. 28296-28311

Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance Review

Markus Morkel, Pamela Riemer, Hendrik BlÃ¤ker, Christine Sers

Published Jul 30, 2015 · Vol. 6, No. 25 · pp. 20785-20800

BRAF mutation testing with a rapid, fully integrated molecular diagnostics system Research Paper

Filip Janku, Bart Claes, Helen J. Huang, Gerald S. Falchook, Benoit Devogelaere, Mark Kockx, Isabelle Vanden Bempt, Martin Reijans, Aung Naing, Siqing Fu, Sarina A. Piha-Paul, David S. Hong, Veronica R. Holley, Apostolia M. Tsimberidou, Vanda M. Stepanek, Sapna P. Patel, E. Scott Kopetz, Vivek Subbiah, Jennifer J. Wheler, Ralph G. Zinner, Daniel D. Karp, Rajyalakshmi Luthra, Sinchita Roy-Chowdhuri, Erwin Sablon, Funda Meric-Bernstam, Geert Maertens, Razelle Kurzrock

Published Jul 27, 2015 · Vol. 6, No. 29 · pp. 26886-26894

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Mutational profiling of colorectal cancers with microsatellite instability Research Paper

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide Research Paper

Overexpression of Mcl-1 confers resistance to BRAF^V600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients Research Paper

Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1 Research Paper

Effects of a novel Nodal-targeting monoclonal antibody in melanoma Priority Research Paper

Biomarker-based prognostic stratification of young adult glioblastoma Clinical Research Papers

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts Research Paper

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway Research Paper

What links BRAF to the heart function? new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment Review

LGR5 is associated with tumor aggressiveness in papillary thyroid cancer Research Paper

Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma Research Paper

A constitutive active MAPK/ERK pathway due to BRAF^V600E positively regulates AHR pathway in PTC Research Paper

Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age Research Paper

Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin Research Paper

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics Research Paper

Disulfiram anti-cancer efficacy without copper overload is enhanced by extracellular H₂O₂ generation: antagonism by tetrathiomolybdate Research Paper

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells Research Paper

Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance Review

BRAF mutation testing with a rapid, fully integrated molecular diagnostics system Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Mutational profiling of colorectal cancers with microsatellite instability Research Paper

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide Research Paper

Overexpression of Mcl-1 confers resistance to BRAFV600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients Research Paper

Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1 Research Paper

Effects of a novel Nodal-targeting monoclonal antibody in melanoma Priority Research Paper

Biomarker-based prognostic stratification of young adult glioblastoma Clinical Research Papers

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts Research Paper

Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway Research Paper

What links BRAF to the heart function? new insights from the cardiotoxicity of BRAF inhibitors in cancer treatment Review

LGR5 is associated with tumor aggressiveness in papillary thyroid cancer Research Paper

Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma Research Paper

A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC Research Paper

Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age Research Paper

Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin Research Paper

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics Research Paper

Disulfiram anti-cancer efficacy without copper overload is enhanced by extracellular H2O2 generation: antagonism by tetrathiomolybdate Research Paper

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells Research Paper

Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance Review

BRAF mutation testing with a rapid, fully integrated molecular diagnostics system Research Paper

Overexpression of Mcl-1 confers resistance to BRAF^V600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper

A constitutive active MAPK/ERK pathway due to BRAF^V600E positively regulates AHR pathway in PTC Research Paper

Disulfiram anti-cancer efficacy without copper overload is enhanced by extracellular H₂O₂ generation: antagonism by tetrathiomolybdate Research Paper