Oncotarget
ERα expression increases in prostate cancer. See Takizawa et al..
Base excision DNA repair and cancer |
https://doi.org/10.18632/oncotarget.2705 Gianluca Tell, and Bruce Demple |
584-585 |
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TORC2 inhibition may boost DNA-damaging chemotherapy |
https://doi.org/10.18632/oncotarget.3034 Manuel Stucki |
586-587 |
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Predicting response to HER2 kinase inhibition |
https://doi.org/10.18632/oncotarget.3036 Jeff Settleman |
588-589 |
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Aging interventions get human |
https://doi.org/10.18632/oncotarget.3173 Brian K. Kennedy, and Juniper K. Pennypacker |
590-591 |
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Androgen receptors beyond prostate cancer: an old marker as a new target |
https://doi.org/10.18632/oncotarget.2831 Javier Munoz, Jennifer J. Wheler, and Razelle Kurzrock |
592-603 |
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Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity |
https://doi.org/10.18632/oncotarget.2820 Itsuhiro Takizawa, Mitchell G. Lawrence, Preetika Balanathan, Richard Rebello, Helen B. Pearson, Elika Garg, John Pedersen, Normand Pouliot, Robert Nadon, Matthew J. Watt, Renea A. Taylor, Patrick Humbert, Ivan Topisirovic, Ola Larsson, Gail P. Risbridger, and Luc Furic |
604-616 |
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Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells |
https://doi.org/10.18632/oncotarget.2710 Franziska Schmidt, Meike Kunze, Ann-Christine Loock, and Matthias Dobbelstein |
617-632 |
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Impact of age on the survival of patients with liver cancer: an analysis of 27,255 patients in the SEER database |
https://doi.org/10.18632/oncotarget.2719 Wenjie Zhang, and Beicheng Sun |
633-641 |
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Synthetic Aβ peptides acquire prion-like properties in the brain |
https://doi.org/10.18632/oncotarget.2819 Xiangzhu Xiao, Ignazio Cali, Jue Yuan, Laura Cracco, Paul Curtiss, Liang Zeng, Mai Abouelsaad, Dimitris Gazgalis, Gong-Xian Wang, Qingzhong Kong, Hisashi Fujioka, Gianfranco Puoti, and Wen-Quan Zou |
642-650 |
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Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells |
https://doi.org/10.18632/oncotarget.2892 Keita Shibuya, Masashi Okada, Shuhei Suzuki, Manabu Seino, Shizuka Seino, Hiroyuki Takeda, and Chifumi Kitanaka |
651-661 |
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Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers |
https://doi.org/10.18632/oncotarget.2689 Ritu Arora, David Schmitt, Balasubramanyam Karanam, Ming Tan, Clayton Yates, and Windy Dean-Colomb |
662-678 |
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IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment |
https://doi.org/10.18632/oncotarget.2707 Jon N Buzzelli, Dan I Pavlic, Heather V Chalinor, Louise O’Connor, Trevelyan R Menheniott, Andrew S Giraud, and Louise M Judd |
679-695 |
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Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS |
https://doi.org/10.18632/oncotarget.2673 Barbie Taylor-Harding, Paul-Joseph Aspuria, Hasmik Agadjanian, Dong-Joo Cheon, Takako Mizuno, Danielle Greenberg, Jenieke R. Allen, Lindsay Spurka, Vincent Funari, Elizabeth Spiteri, Qiang Wang, Sandra Orsulic, Christine Walsh, Beth Y. Karlan, and Ruprecht W. Wiedemeyer |
696-714 |
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Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts |
https://doi.org/10.18632/oncotarget.2711 Ridwana Chowdhury, Jason P. Webber, Mark Gurney, Malcolm D. Mason, Zsuzsanna Tabi, and Aled Clayton |
715-731 |
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SWI/SNF complexes are required for full activation of the DNA-damage response |
https://doi.org/10.18632/oncotarget.2715 Stephanie L. Smith-Roe, Jun Nakamura, Darcy Holley, Paul D. Chastain, Gary B. Rosson, Dennis A. Simpson, John R. Ridpath, David G. Kaufman, William K. Kaufmann, and Scott J. Bultman |
732-745 |
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A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor |
https://doi.org/10.18632/oncotarget.2685 Odile Gayet, Celine Loncle, Pauline Duconseil, Marine Gilabert, Maria Belen Lopez, Vincent Moutardier, Olivier Turrini, Ezequiel Calvo, Jacques Ewald, Marc Giovannini, Mohamed Gasmi, Erwan Bories, Marc Barthet, Mehdi Ouaissi, Anthony Goncalves, Flora Poizat, Jean Luc Raoul, Veronique Secq, Stephane Garcia, Patrice Viens, Nelson Dusetti, and Juan Iovanna |
746-754 |
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The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients |
https://doi.org/10.18632/oncotarget.2712 David G. Darcy, Rachel Chiaroni-Clarke, Jennifer M. Murphy, Joshua N. Honeyman, Umesh Bhanot, Michael P. LaQuaglia, and Sanford M. Simon |
755-770 |
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SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination |
https://doi.org/10.18632/oncotarget.2718 Wenfu Lu, Shenji Liu, Bo Li, Yingqiu Xie, Christine Adhiambo, Qing Yang, Billy R. Ballard, Keiichi I. Nakayama, Robert J. Matusik, and Zhenbang Chen |
771-788 |
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P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis |
https://doi.org/10.18632/oncotarget.2733 Jun Zhang, Ke Ma, Tingting Qi, Xiaoning Wei, Qing Zhang, Guanwu Li, and Jen-Fu Chiu |
789-801 |
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The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy |
https://doi.org/10.18632/oncotarget.2742 Michael Ehrhardt, Rogerio B. Craveiro, Martin I. Holst, Torsten Pietsch, and Dagmar Dilloo |
802-813 |
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Short-hairpin RNA library: identification of therapeutic partners for gefitinib-resistant non-small cell lung cancer |
https://doi.org/10.18632/oncotarget.2891 Makoto Sudo, Seiichi Mori, Vikas Madan, Henry Yang, Geraldine Leong, and H. Phillip Koeffler |
814-824 |
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c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia |
https://doi.org/10.18632/oncotarget.2706 Kirsten Kübler, Sally Heinenberg, Christian Rudlowski, Mignon-Denise Keyver-Paik, Alina Abramian, Sabine Merkelbach-Bruse, Reinhard Büttner, Walther Kuhn, and Hans-Ulrich Schildhaus |
825-835 |
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The inverse relationship between bladder and liver in 4-aminobiphenyl-induced DNA damage |
https://doi.org/10.18632/oncotarget.2722 Arup Bhattacharya, Joshua J. Klaene, Yun Li, Joseph D. Paonessa, Aimee B. Stablewski, Paul Vouros, and Yuesheng Zhang |
836-845 |
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PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma |
https://doi.org/10.18632/oncotarget.2749 Wei-Ren Liu, Meng-Xin Tian, Liu-Xiao Yang, Yu-Li Lin, Lei Jin, Zhen-Bin Ding, Ying-Hao Shen, Yuan-Fei Peng, Dong-Mei Gao, Jian Zhou, Shuang-Jian Qiu, Zhi Dai, Rui He, Jia Fan, and Ying-Hong Shi |
846-861 |
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The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer |
https://doi.org/10.18632/oncotarget.2696 Anna Chen, Christina S.F. Wong, Mira C.P. Liu, Colin M. House, Jaclyn Sceneay, David D. Bowtell, Erik W. Thompson, and Andreas Möller |
862-873 |
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TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer |
https://doi.org/10.18632/oncotarget.2716 José A. Galván, Melina Helbling, Viktor H. Koelzer, Mario P. Tschan, Martin D. Berger, Marion Hädrich, Beat Schnüriger, Eva Karamitopoulou, Heather Dawson, Daniel Inderbitzin, Alessandro Lugli, and Inti Zlobec |
874-885 |
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HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape |
https://doi.org/10.18632/oncotarget.2816 Mariarosaria Conte, Carmela Dell’Aversana, Rosaria Benedetti, Francesca Petraglia, Annamaria Carissimo, Valeria Belsito Petrizzi, Alfonso Maria D’Arco, Ciro Abbondanza, Angela Nebbioso, and Lucia Altucci |
886-901 |
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An HSV-2 based oncolytic virus can function as an attractant to guide migration of adoptively transferred T cells to tumor sites |
https://doi.org/10.18632/oncotarget.2817 Xinping Fu, Armando Rivera, Lihua Tao, and Xiaoliu Zhang |
902-914 |
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DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study |
https://doi.org/10.18632/oncotarget.2821 Hon-Yi Lin, Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Tze-Ta Huang, Chih-En Tseng, Liang-Yu Shih, Ru-Inn Lin, Jora M.J. Lin, Yi-Hui Lai, Chia-Bin Chang, Feng-Chun Hsu, Liang-Cheng Chen, Shiang-Jiun Tsai, Yu-Chieh Su, Szu-Chi Li, Hung-Chih Lai, Wen-Lin Hsu, Dai-Wei Liu, Chien-Kuo Tai, Shu-Fen Wu, and Michael W.Y. Chan |
915-934 |
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FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 |
https://doi.org/10.18632/oncotarget.2822 Rui Liu, Shan Huang, Yunlong Lei, Tao Zhang, Kui Wang, Bo Liu, Edouard C. Nice, Rong Xiang, Ke Xie, Jingyi Li, and Canhua Huang |
935-952 |
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EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity |
https://doi.org/10.18632/oncotarget.2823 Paul L. Colbert, Daniel W. Vermeer, Bryant G. Wieking, John H. Lee, and Paola D. Vermeer |
953-968 |
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Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer |
https://doi.org/10.18632/oncotarget.2824 Igor Vujic, Martina Sanlorenzo, Christian Posch, Rosaura Esteve-Puig, Adam J. Yen, Andrew Kwong, Aaron Tsumura, Ryan Murphy, Klemens Rappersberger, and Susana Ortiz-Urda |
969-978 |
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Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors |
https://doi.org/10.18632/oncotarget.2825 Ming Xu, Changhong Zhu, Xian Zhao, Cheng Chen, Hailong Zhang, Haihua Yuan, Rong Deng, Jinzhuo Dou, Yanli Wang, Jian Huang, Qin Chen, Bin Jiang, and Jianxiu Yu |
979-994 |
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Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer |
https://doi.org/10.18632/oncotarget.2739 Hui-Ling Huang, Chi-Hsiang Chiang, Wen-Chun Hung, and Ming-Feng Hou |
995-1007 |
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Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells |
https://doi.org/10.18632/oncotarget.2826 Takuya Nakamura, Satoru Shinriki, Hirofumi Jono, Jianying Guo, Mitsuharu Ueda, Mitsuhiro Hayashi, Satoshi Yamashita, Andries Zijlstra, Hideki Nakayama, Akimitsu Hiraki, Masanori Shinohara, and Yukio Ando |
1008-1019 |
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Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin |
https://doi.org/10.18632/oncotarget.2741 Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du, and Guojun Zhang |
1020-1030 |
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Reciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells |
https://doi.org/10.18632/oncotarget.2671 Juan Li, Tian Lan, Cuixiang Zhang, Cheng Zeng, Jincai Hou, Zhicheng Yang, Min Zhang, Jianxun Liu, and Bing Liu |
1031-1048 |
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ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA |
https://doi.org/10.18632/oncotarget.2832 Hongxin Ma, Xuetian Yue, Lifen Gao, Xiaohong Liang, Wenjiang Yan, Zhenyu Zhang, Haixia Shan, Hualin Zhang, Brett T. Spear, and Chunhong Ma |
1049-1063 |
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Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer |
https://doi.org/10.18632/oncotarget.2833 Fengjin Zhao, Tianxin Lin, Wang He, Jinli Han, Dingjun Zhu, Kaishun Hu, Weicong Li, Zaosong Zheng, Jian Huang, and Wenlian Xie |
1064-1078 |
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Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models |
https://doi.org/10.18632/oncotarget.2835 Huanzhang Hu, Yinghe Qiu, Minggao Guo, Yao Huang, Lin Fang, Zhangxiao Peng, Weidan Ji, Yang Xu, Shuwen Shen, Yan Yan, Xuandong Huang, Junnian Zheng, and Changqing Su |
1079-1089 |
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The microRNA-218~Survivin axis regulates migration, invasion, and lymph node metastasis in cervical cancer |
https://doi.org/10.18632/oncotarget.2836 Ryunosuke Kogo, Christine How, Naz Chaudary, Jeff Bruce, Wei Shi, Richard P. Hill, Payam Zahedi, Kenneth W. Yip, and Fei-Fei Liu |
1090-1100 |
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MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation |
https://doi.org/10.18632/oncotarget.2728 Yuhuang Li, Kishore B Challagundla, Xiao-Xin Sun, Qinghong Zhang, and Mu-Shui Dai |
1101-1114 |
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Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma |
https://doi.org/10.18632/oncotarget.2747 Stephen Q. Wong, Andreas Behren, Victoria J. Mar, Katherine Woods, Jason Li, Claire Martin, Karen E. Sheppard, Rory Wolfe, John Kelly, Jonathan Cebon, Alexander Dobrovic, and Grant A. McArthur |
1115-1127 |
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Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma |
https://doi.org/10.18632/oncotarget.2731 Iris Chiara Salaroglio, Ivana Campia, Joanna Kopecka, Elena Gazzano, Sara Orecchia, Dario Ghigo, and Chiara Riganti |
1128-1142 |
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Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance |
https://doi.org/10.18632/oncotarget.2732 Benny Zhitomirsky, and Yehuda G. Assaraf |
1143-1156 |
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Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction |
https://doi.org/10.18632/oncotarget.2708 Valentina Fogal, Ivan Babic, Ying Chao, Sandra Pastorino, Rajesh Mukthavaram, Pengfei Jiang, Yoon-Jae Cho, Sandeep C. Pingle, John R. Crawford, David E. Piccioni, and Santosh Kesari |
1157-1170 |
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Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells |
https://doi.org/10.18632/oncotarget.2645 Jie Qiao, Shu-Jian Cui, Lei-Lei Xu, Si-Jie Chen, Jun Yao, Ying-Hua Jiang, Gang Peng, Cai-Yun Fang, Peng-Yuan Yang, and Feng Liu |
1171-1189 |
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Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level |
https://doi.org/10.18632/oncotarget.2778 Jessian L. Munoz, Vivian Rodriguez-Cruz, Shakti H. Ramkissoon, Keith L. Ligon, Steven J. Greco, and Pranela Rameshwar |
1190-1201 |
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A switch from CD44+ cell to EMT cell drives the metastasis of prostate cancer |
https://doi.org/10.18632/oncotarget.2841 Zhiqun Shang, Qiliang Cai, Minghao Zhang, Shimiao Zhu, Yuan Ma, Libin Sun, Ning Jiang, Jing Tian, Xiaodan Niu, Jiatong Chen, Yinghao Sun, and Yuanjie Niu |
1202-1216 |
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Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment |
https://doi.org/10.18632/oncotarget.2721 Vitalba Ruggieri, Francesca Agriesti, Rosella Scrima, Ilaria Laurenzana, Donatella Perrone, Tiziana Tataranni, Carmela Mazzoccoli, Lorenzo Lo Muzio, Nazzareno Capitanio, and Claudia Piccoli |
1217-1230 |
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Aspartate β-hydroxylase expression promotes a malignant pancreatic cellular phenotype |
https://doi.org/10.18632/oncotarget.2840 Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, and Jack R. Wands |
1231-1248 |
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Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia |
https://doi.org/10.18632/oncotarget.2859 Minran Zhou, Jiping Zeng, Xiaoming Wang, Xiangyu Wang, Tao Huang, Yue Fu, Ting Sun, Jihui Jia, and Chunyan Chen |
1249-1261 |
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The Na+/H+ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells |
https://doi.org/10.18632/oncotarget.2860 Schammim Ray Amith, Jodi Marie Wilkinson, Shairaz Baksh, and Larry Fliegel |
1262-1275 |
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miR-26a and miR-214 down-regulate expression of the PTEN gene in chronic lymphocytic leukemia, but not PTEN mutation or promoter methylation |
https://doi.org/10.18632/oncotarget.2626 Zhi-Jian Zou, Lei Fan, Li Wang, Ji Xu, Run Zhang, Tian Tian, Jian-Yong Li, and Wei Xu |
1276-1285 |
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A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors |
https://doi.org/10.18632/oncotarget.2676 Farah B. Rahmatpanah, Zhenyu Jia, Xin Chen, Jessica E. Char, Bozhao Men, Anna-Clara Franke, Frank E. Jones, Michael McClelland, and Dan Mercola |
1286-1301 |
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Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity |
https://doi.org/10.18632/oncotarget.2744 Malte Krönig, Max Walter, Vanessa Drendel, Martin Werner, Cordula A. Jilg, Andreas S. Richter, Rolf Backofen, David McGarry, Marie Follo, Wolfgang Schultze-Seemann, and Roland Schüle |
1302-1314 |
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PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies |
https://doi.org/10.18632/oncotarget.2834 Matthias Scheffler, Marc Bos, Masyar Gardizi, Katharina König, Sebastian Michels, Jana Fassunke, Carina Heydt, Helen Künstlinger, Michaela Ihle, Frank Ueckeroth, Kerstin Albus, Monika Serke, Ulrich Gerigk, Wolfgang Schulte, Karin Töpelt, Lucia Nogova, Thomas Zander, Walburga Engel-Riedel, Erich Stoelben, Yon-Dschun Ko, Winfried Randerath, Britta Kaminsky, Jens Panse, Carolin Becker, Martin Hellmich, Sabine Merkelbach-Bruse, Lukas C. Heukamp, Reinhard Büttner, and Jürgen Wolf |
1315-1326 |
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Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients |
https://doi.org/10.18632/oncotarget.2675 Anna Berg, Erling A. Hoivik, Siv Mjøs, Frederik Holst, Henrica M. J. Werner, Ingvild L. Tangen, Amaro Taylor-Weiner, William J. Gibson, Kanthida Kusonmano, Elisabeth Wik, Jone Trovik, Mari K. Halle, Anne M. Øyan, Karl-Henning Kalland, Andrew D. Cherniack, Rameen Beroukhim, Ingunn Stefansson, Gordon B. Mills, Camilla Krakstad, and Helga B. Salvesen |
1327-1339 |
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