|
| Base excision DNA repair and cancer |
|
https://doi.org/10.18632/oncotarget.2705
Gianluca Tell, and Bruce Demple
|
| 584-585 |
|
| TORC2 inhibition may boost DNAdamaging chemotherapy |
|
https://doi.org/10.18632/oncotarget.3034
Manuel Stucki
|
| 586-587 |
|
| Predicting response to HER2 kinase inhibition |
|
https://doi.org/10.18632/oncotarget.3036
Jeff Settleman
|
| 588-589 |
|
| Aging interventions get human |
|
https://doi.org/10.18632/oncotarget.3173
Brian K. Kennedy, and Juniper K. Pennypacker
|
| 590-591 |
|
| Androgen receptors beyond prostate cancer: an old marker as a new target |
|
https://doi.org/10.18632/oncotarget.2831
Javier Munoz, Jennifer J. Wheler, and Razelle Kurzrock
|
| 592-603 |
|
| Estrogen receptor alpha drives proliferation in PTENdeficient prostate carcinoma by stimulating survival signaling MYC expression and altering glucose sensitivity |
|
https://doi.org/10.18632/oncotarget.2820
Itsuhiro Takizawa, Mitchell G. Lawrence, Preetika Balanathan, Richard Rebello, Helen B. Pearson, Elika Garg, John Pedersen, Normand Pouliot, Robert Nadon, Matthew J. Watt, Renea A. Taylor, Patrick Humbert, Ivan Topisirovic, Ola Larsson, Gail P. Risbridger, and Luc Furic
|
| 604-616 |
|
| Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells |
|
https://doi.org/10.18632/oncotarget.2710
Franziska Schmidt, Meike Kunze, Ann-Christine Loock, and Matthias Dobbelstein
|
| 617-632 |
|
| Impact of age on the survival of patients with liver cancer: an analysis of 27255 patients in the SEER database |
|
https://doi.org/10.18632/oncotarget.2719
Wenjie Zhang, and Beicheng Sun
|
| 633-641 |
|
| Synthetic Aβ peptides acquire prionlike properties in the brain |
|
https://doi.org/10.18632/oncotarget.2819
Xiangzhu Xiao, Ignazio Cali, Jue Yuan, Laura Cracco, Paul Curtiss, Liang Zeng, Mai Abouelsaad, Dimitris Gazgalis, Gong-Xian Wang, Qingzhong Kong, Hisashi Fujioka, Gianfranco Puoti, and Wen-Quan Zou
|
| 642-650 |
|
| Targeting the facilitative glucose transporter GLUT1 inhibits the selfrenewal and tumorinitiating capacity of cancer stem cells |
|
https://doi.org/10.18632/oncotarget.2892
Keita Shibuya, Masashi Okada, Shuhei Suzuki, Manabu Seino, Shizuka Seino, Hiroyuki Takeda, and Chifumi Kitanaka
|
| 651-661 |
|
| Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers |
|
https://doi.org/10.18632/oncotarget.2689
Ritu Arora, David Schmitt, Balasubramanyam Karanam, Ming Tan, Clayton Yates, and Windy Dean-Colomb
|
| 662-678 |
|
| IL1RT1 signaling antagonizes IL11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment |
|
https://doi.org/10.18632/oncotarget.2707
Jon N Buzzelli, Dan I Pavlic, Heather V Chalinor, Louise O’Connor, Trevelyan R Menheniott, Andrew S Giraud, and Louise M Judd
|
| 679-695 |
|
| Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS |
|
https://doi.org/10.18632/oncotarget.2673
Barbie Taylor-Harding, Paul-Joseph Aspuria, Hasmik Agadjanian, Dong-Joo Cheon, Takako Mizuno, Danielle Greenberg, Jenieke R. Allen, Lindsay Spurka, Vincent Funari, Elizabeth Spiteri, Qiang Wang, Sandra Orsulic, Christine Walsh, Beth Y. Karlan, and Ruprecht W. Wiedemeyer
|
| 696-714 |
|
| Cancer exosomes trigger mesenchymal stem cell differentiation into proangiogenic and proinvasive myofibroblasts |
|
https://doi.org/10.18632/oncotarget.2711
Ridwana Chowdhury, Jason P. Webber, Mark Gurney, Malcolm D. Mason, Zsuzsanna Tabi, and Aled Clayton
|
| 715-731 |
|
| SWI/SNF complexes are required for full activation of the DNAdamage response |
|
https://doi.org/10.18632/oncotarget.2715
Stephanie L. Smith-Roe, Jun Nakamura, Darcy Holley, Paul D. Chastain, Gary B. Rosson, Dennis A. Simpson, John R. Ridpath, David G. Kaufman, William K. Kaufmann, and Scott J. Bultman
|
| 732-745 |
|
| A subgroup of pancreatic adenocarcinoma is sensitive to the 5azadC DNA methyltransferase inhibitor |
|
https://doi.org/10.18632/oncotarget.2685
Odile Gayet, Celine Loncle, Pauline Duconseil, Marine Gilabert, Maria Belen Lopez, Vincent Moutardier, Olivier Turrini, Ezequiel Calvo, Jacques Ewald, Marc Giovannini, Mohamed Gasmi, Erwan Bories, Marc Barthet, Mehdi Ouaissi, Anthony Goncalves, Flora Poizat, Jean Luc Raoul, Veronique Secq, Stephane Garcia, Patrice Viens, Nelson Dusetti, and Juan Iovanna
|
| 746-754 |
|
| The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients |
|
https://doi.org/10.18632/oncotarget.2712
David G. Darcy, Rachel Chiaroni-Clarke, Jennifer M. Murphy, Joshua N. Honeyman, Umesh Bhanot, Michael P. LaQuaglia, and Sanford M. Simon
|
| 755-770 |
|
| SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination |
|
https://doi.org/10.18632/oncotarget.2718
Wenfu Lu, Shenji Liu, Bo Li, Yingqiu Xie, Christine Adhiambo, Qing Yang, Billy R. Ballard, Keiichi I. Nakayama, Robert J. Matusik, and Zhenbang Chen
|
| 771-788 |
|
| P62 regulates resveratrolmediated Fas/Cav1 complex formation and transition from autophagy to apoptosis |
|
https://doi.org/10.18632/oncotarget.2733
Jun Zhang, Ke Ma, Tingting Qi, Xiaoning Wei, Qing Zhang, Guanwu Li, and Jen-Fu Chiu
|
| 789-801 |
|
| The PI3K inhibitor GDC0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy |
|
https://doi.org/10.18632/oncotarget.2742
Michael Ehrhardt, Rogerio B. Craveiro, Martin I. Holst, Torsten Pietsch, and Dagmar Dilloo
|
| 802-813 |
|
| Shorthairpin RNA library: identification of therapeutic partners for gefitinibresistant nonsmall cell lung cancer |
|
https://doi.org/10.18632/oncotarget.2891
Makoto Sudo, Seiichi Mori, Vikas Madan, Henry Yang, Geraldine Leong, and H. Phillip Koeffler
|
| 814-824 |
|
| cmyc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia |
|
https://doi.org/10.18632/oncotarget.2706
Kirsten Kübler, Sally Heinenberg, Christian Rudlowski, Mignon-Denise Keyver-Paik, Alina Abramian, Sabine Merkelbach-Bruse, Reinhard Büttner, Walther Kuhn, and Hans-Ulrich Schildhaus
|
| 825-835 |
|
| The inverse relationship between bladder and liver in 4aminobiphenylinduced DNA damage |
|
https://doi.org/10.18632/oncotarget.2722
Arup Bhattacharya, Joshua J. Klaene, Yun Li, Joseph D. Paonessa, Aimee B. Stablewski, Paul Vouros, and Yuesheng Zhang
|
| 836-845 |
|
| PKM2 promotes metastasis by recruiting myeloidderived suppressor cells and indicates poor prognosis for hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2749
Wei-Ren Liu, Meng-Xin Tian, Liu-Xiao Yang, Yu-Li Lin, Lei Jin, Zhen-Bin Ding, Ying-Hao Shen, Yuan-Fei Peng, Dong-Mei Gao, Jian Zhou, Shuang-Jian Qiu, Zhi Dai, Rui He, Jia Fan, and Ying-Hong Shi
|
| 846-861 |
|
| The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer |
|
https://doi.org/10.18632/oncotarget.2696
Anna Chen, Christina S.F. Wong, Mira C.P. Liu, Colin M. House, Jaclyn Sceneay, David D. Bowtell, Erik W. Thompson, and Andreas Möller
|
| 862-873 |
|
| TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelialmesenchymal transitionlike tumor budding phenotype in colorectal cancer |
|
https://doi.org/10.18632/oncotarget.2716
José A. Galván, Melina Helbling, Viktor H. Koelzer, Mario P. Tschan, Martin D. Berger, Marion Hädrich, Beat Schnüriger, Eva Karamitopoulou, Heather Dawson, Daniel Inderbitzin, Alessandro Lugli, and Inti Zlobec
|
| 874-885 |
|
| HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape |
|
https://doi.org/10.18632/oncotarget.2816
Mariarosaria Conte, Carmela Dell’Aversana, Rosaria Benedetti, Francesca Petraglia, Annamaria Carissimo, Valeria Belsito Petrizzi, Alfonso Maria D’Arco, Ciro Abbondanza, Angela Nebbioso, and Lucia Altucci
|
| 886-901 |
|
| An HSV2 based oncolytic virus can function as an attractant to guide migration of adoptively transferred T cells to tumor sites |
|
https://doi.org/10.18632/oncotarget.2817
Xinping Fu, Armando Rivera, Lihua Tao, and Xiaoliu Zhang
|
| 902-914 |
|
| DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcomepredicting and treatmentimplicating study |
|
https://doi.org/10.18632/oncotarget.2821
Hon-Yi Lin, Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Tze-Ta Huang, Chih-En Tseng, Liang-Yu Shih, Ru-Inn Lin, Jora M.J. Lin, Yi-Hui Lai, Chia-Bin Chang, Feng-Chun Hsu, Liang-Cheng Chen, Shiang-Jiun Tsai, Yu-Chieh Su, Szu-Chi Li, Hung-Chih Lai, Wen-Lin Hsu, Dai-Wei Liu, Chien-Kuo Tai, Shu-Fen Wu, and Michael W.Y. Chan
|
| 915-934 |
|
| FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 |
|
https://doi.org/10.18632/oncotarget.2822
Rui Liu, Shan Huang, Yunlong Lei, Tao Zhang, Kui Wang, Bo Liu, Edouard C. Nice, Rong Xiang, Ke Xie, Jingyi Li, and Canhua Huang
|
| 935-952 |
|
| EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity |
|
https://doi.org/10.18632/oncotarget.2823
Paul L. Colbert, Daniel W. Vermeer, Bryant G. Wieking, John H. Lee, and Paola D. Vermeer
|
| 953-968 |
|
| Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer |
|
https://doi.org/10.18632/oncotarget.2824
Igor Vujic, Martina Sanlorenzo, Christian Posch, Rosaura Esteve-Puig, Adam J. Yen, Andrew Kwong, Aaron Tsumura, Ryan Murphy, Klemens Rappersberger, and Susana Ortiz-Urda
|
| 969-978 |
|
| Atypical ubiquitin E3 ligase complex Skp1PamFbxo45 controls the core epithelialtomesenchymal transitioninducing transcription factors |
|
https://doi.org/10.18632/oncotarget.2825
Ming Xu, Changhong Zhu, Xian Zhao, Cheng Chen, Hailong Zhang, Haihua Yuan, Rong Deng, Jinzhuo Dou, Yanli Wang, Jian Huang, Qin Chen, Bin Jiang, and Jianxiu Yu
|
| 979-994 |
|
| Targeting of TGFβactivated protein kinase 1 inhibits chemokine CC motif receptor 7 expression tumor growth and metastasis in breast cancer |
|
https://doi.org/10.18632/oncotarget.2739
Hui-Ling Huang, Chi-Hsiang Chiang, Wen-Chun Hung, and Ming-Feng Hou
|
| 995-1007 |
|
| Intrinsic TGFβ2triggered SDF1CXCR4 signaling axis is crucial for drug resistance and a slowcycling state in bone marrowdisseminated tumor cells |
|
https://doi.org/10.18632/oncotarget.2826
Takuya Nakamura, Satoru Shinriki, Hirofumi Jono, Jianying Guo, Mitsuharu Ueda, Mitsuhiro Hayashi, Satoshi Yamashita, Andries Zijlstra, Hideki Nakayama, Akimitsu Hiraki, Masanori Shinohara, and Yukio Ando
|
| 1008-1019 |
|
| Silencing of CXCR4 sensitizes triplenegative breast cancer cells to cisplatin |
|
https://doi.org/10.18632/oncotarget.2741
Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du, and Guojun Zhang
|
| 1020-1030 |
|
| Reciprocal activation between IL6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of nonsmall cell lung cancer cells |
|
https://doi.org/10.18632/oncotarget.2671
Juan Li, Tian Lan, Cuixiang Zhang, Cheng Zeng, Jincai Hou, Zhicheng Yang, Min Zhang, Jianxun Liu, and Bing Liu
|
| 1031-1048 |
|
| ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NFYA |
|
https://doi.org/10.18632/oncotarget.2832
Hongxin Ma, Xuetian Yue, Lifen Gao, Xiaohong Liang, Wenjiang Yan, Zhenyu Zhang, Haixia Shan, Hualin Zhang, Brett T. Spear, and Chunhong Ma
|
| 1049-1063 |
|
| Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer |
|
https://doi.org/10.18632/oncotarget.2833
Fengjin Zhao, Tianxin Lin, Wang He, Jinli Han, Dingjun Zhu, Kaishun Hu, Weicong Li, Zaosong Zheng, Jian Huang, and Wenlian Xie
|
| 1064-1078 |
|
| Targeted Hsp70 expression combined with CIKactivated immune reconstruction synergistically exerts antitumor efficacy in patientderived hepatocellular carcinoma xenograft mouse models |
|
https://doi.org/10.18632/oncotarget.2835
Huanzhang Hu, Yinghe Qiu, Minggao Guo, Yao Huang, Lin Fang, Zhangxiao Peng, Weidan Ji, Yang Xu, Shuwen Shen, Yan Yan, Xuandong Huang, Junnian Zheng, and Changqing Su
|
| 1079-1089 |
|
| The microRNA218~Survivin axis regulates migration invasion and lymph node metastasis in cervical cancer |
|
https://doi.org/10.18632/oncotarget.2836
Ryunosuke Kogo, Christine How, Naz Chaudary, Jeff Bruce, Wei Shi, Richard P. Hill, Payam Zahedi, Kenneth W. Yip, and Fei-Fei Liu
|
| 1090-1100 |
|
| MicroRNA130a associates with ribosomal protein L11 to suppress cMyc expression in response to UV irradiation |
|
https://doi.org/10.18632/oncotarget.2728
Yuhuang Li, Kishore B Challagundla, Xiao-Xin Sun, Qinghong Zhang, and Mu-Shui Dai
|
| 1101-1114 |
|
| Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma |
|
https://doi.org/10.18632/oncotarget.2747
Stephen Q. Wong, Andreas Behren, Victoria J. Mar, Katherine Woods, Jason Li, Claire Martin, Karen E. Sheppard, Rory Wolfe, John Kelly, Jonathan Cebon, Alexander Dobrovic, and Grant A. McArthur
|
| 1115-1127 |
|
| Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma |
|
https://doi.org/10.18632/oncotarget.2731
Iris Chiara Salaroglio, Ivana Campia, Joanna Kopecka, Elena Gazzano, Sara Orecchia, Dario Ghigo, and Chiara Riganti
|
| 1128-1142 |
|
| Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosomedependent cancer multidrug resistance |
|
https://doi.org/10.18632/oncotarget.2732
Benny Zhitomirsky, and Yehuda G. Assaraf
|
| 1143-1156 |
|
| Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction |
|
https://doi.org/10.18632/oncotarget.2708
Valentina Fogal, Ivan Babic, Ying Chao, Sandra Pastorino, Rajesh Mukthavaram, Pengfei Jiang, Yoon-Jae Cho, Sandeep C. Pingle, John R. Crawford, David E. Piccioni, and Santosh Kesari
|
| 1157-1170 |
|
| Filamin C a dysregulated protein in cancer revealed by labelfree quantitative proteomic analyses of human gastric cancer cells |
|
https://doi.org/10.18632/oncotarget.2645
Jie Qiao, Shu-Jian Cui, Lei-Lei Xu, Si-Jie Chen, Jun Yao, Ying-Hua Jiang, Gang Peng, Cai-Yun Fang, Peng-Yuan Yang, and Feng Liu
|
| 1171-1189 |
|
| Temozolomide resistance in glioblastoma occurs by miRNA9targeted PTCH1 independent of sonic hedgehog level |
|
https://doi.org/10.18632/oncotarget.2778
Jessian L. Munoz, Vivian Rodriguez-Cruz, Shakti H. Ramkissoon, Keith L. Ligon, Steven J. Greco, and Pranela Rameshwar
|
| 1190-1201 |
|
| A switch from CD44+ cell to EMT cell drives the metastasis of prostate cancer |
|
https://doi.org/10.18632/oncotarget.2841
Zhiqun Shang, Qiliang Cai, Minghao Zhang, Shimiao Zhu, Yuan Ma, Libin Sun, Ning Jiang, Jing Tian, Xiaodan Niu, Jiatong Chen, Yinghao Sun, and Yuanjie Niu
|
| 1202-1216 |
|
| Dichloroacetate a selective mitochondriatargeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment |
|
https://doi.org/10.18632/oncotarget.2721
Vitalba Ruggieri, Francesca Agriesti, Rosella Scrima, Ilaria Laurenzana, Donatella Perrone, Tiziana Tataranni, Carmela Mazzoccoli, Lorenzo Lo Muzio, Nazzareno Capitanio, and Claudia Piccoli
|
| 1217-1230 |
|
| Aspartate βhydroxylase expression promotes a malignant pancreatic cellular phenotype |
|
https://doi.org/10.18632/oncotarget.2840
Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, and Jack R. Wands
|
| 1231-1248 |
|
| Histone demethylase RBP2 decreases miR21 in blast crisis of chronic myeloid leukemia |
|
https://doi.org/10.18632/oncotarget.2859
Minran Zhou, Jiping Zeng, Xiaoming Wang, Xiangyu Wang, Tao Huang, Yue Fu, Ting Sun, Jihui Jia, and Chunyan Chen
|
| 1249-1261 |
|
| The Na+/H+ exchanger NHE1 as a novel coadjuvant target in paclitaxel therapy of triplenegative breast cancer cells |
|
https://doi.org/10.18632/oncotarget.2860
Schammim Ray Amith, Jodi Marie Wilkinson, Shairaz Baksh, and Larry Fliegel
|
| 1262-1275 |
|
| miR26a and miR214 downregulate expression of the PTEN gene in chronic lymphocytic leukemia but not PTEN mutation or promoter methylation |
|
https://doi.org/10.18632/oncotarget.2626
Zhi-Jian Zou, Lei Fan, Li Wang, Ji Xu, Run Zhang, Tian Tian, Jian-Yong Li, and Wei Xu
|
| 1276-1285 |
|
| A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors |
|
https://doi.org/10.18632/oncotarget.2676
Farah B. Rahmatpanah, Zhenyu Jia, Xin Chen, Jessica E. Char, Bozhao Men, Anna-Clara Franke, Frank E. Jones, Michael McClelland, and Dan Mercola
|
| 1286-1301 |
|
| Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity |
|
https://doi.org/10.18632/oncotarget.2744
Malte Krönig, Max Walter, Vanessa Drendel, Martin Werner, Cordula A. Jilg, Andreas S. Richter, Rolf Backofen, David McGarry, Marie Follo, Wolfgang Schultze-Seemann, and Roland Schüle
|
| 1302-1314 |
|
| PIK3CA mutations in nonsmall cell lung cancer NSCLC: Genetic heterogeneity prognostic impact and incidence of prior malignancies |
|
https://doi.org/10.18632/oncotarget.2834
Matthias Scheffler, Marc Bos, Masyar Gardizi, Katharina König, Sebastian Michels, Jana Fassunke, Carina Heydt, Helen Künstlinger, Michaela Ihle, Frank Ueckeroth, Kerstin Albus, Monika Serke, Ulrich Gerigk, Wolfgang Schulte, Karin Töpelt, Lucia Nogova, Thomas Zander, Walburga Engel-Riedel, Erich Stoelben, Yon-Dschun Ko, Winfried Randerath, Britta Kaminsky, Jens Panse, Carolin Becker, Martin Hellmich, Sabine Merkelbach-Bruse, Lukas C. Heukamp, Reinhard Büttner, and Jürgen Wolf
|
| 1315-1326 |
|
| Molecular profiling of endometrial carcinoma precursor primary and metastatic lesions suggests different targets for treatment in obese compared to nonobese patients |
|
https://doi.org/10.18632/oncotarget.2675
Anna Berg, Erling A. Hoivik, Siv Mjøs, Frederik Holst, Henrica M. J. Werner, Ingvild L. Tangen, Amaro Taylor-Weiner, William J. Gibson, Kanthida Kusonmano, Elisabeth Wik, Jone Trovik, Mari K. Halle, Anne M. Øyan, Karl-Henning Kalland, Andrew D. Cherniack, Rameen Beroukhim, Ingunn Stefansson, Gordon B. Mills, Camilla Krakstad, and Helga B. Salvesen
|
| 1327-1339 |
