Oncotarget
In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential. See Raffeiner et al.
New targets for resistant prostate cancer |
https://doi.org/10.18632/oncotarget.2544 Timothy C. Thompson, and Likun Li |
8816-8817 |
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Axl as a mediator of cellular growth and survival |
https://doi.org/10.18632/oncotarget.2422 Haley Axelrod, and Kenneth J. Pienta |
8818-8852 |
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Hypoxia-inducible factors enhance glutamate signaling in cancer cells |
https://doi.org/10.18632/oncotarget.2593 Hongxia Hu, Naoharu Takano, Lisha Xiang, Daniele M. Gilkes, Weibo Luo, and Gregg L. Semenza |
8853-8868 |
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In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential |
https://doi.org/10.18632/oncotarget.2588 Philipp Raffeiner, Ruth Röck, Andrea Schraffl, Markus Hartl, Jonathan R. Hart, Kim D. Janda, Peter K. Vogt, Eduard Stefan, and Klaus Bister |
8869-8878 |
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Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism |
https://doi.org/10.18632/oncotarget.2432 Xin Yu, Adam R. Blanden, Sumana Narayanan, Lalithapriya Jayakumar, David Lubin, David Augeri, S. David Kimball, Stewart N. Loh, and Darren R. Carpizo |
8879-8892 |
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MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells |
https://doi.org/10.18632/oncotarget.2360 Akriti Kharbanda, Hasan Rajabi, Caining Jin, Maroof Alam, Kwok-Kin Wong, and Donald Kufe |
8893-8905 |
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The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies |
https://doi.org/10.18632/oncotarget.2417 Daniel Martin, Martin C. Abba, Alfredo A. Molinolo, Lynn Vitale-Cross, Zhiyong Wang, Moraima Zaida, Naomi C. Delic, Yardena Samuels, Guy J. Lyons, and J. Silvio Gutkind |
8906-8923 |
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Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells |
https://doi.org/10.18632/oncotarget.2441 Lan Yi, Yvonne Sun, and Arnold Levine |
8924-8936 |
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Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials |
https://doi.org/10.18632/oncotarget.2339 Rabih Said, Yang Ye, Gerald Steven Falchook, Filip Janku, Aung Naing, Ralph Zinner, George R. Blumenschein Jr, Siqing Fu, David S. Hong, Sarina Anne Piha-Paul, Jennifer J. Wheler, Razelle Kurzrock, Gary A. Palmer, Kenneth Aldape, Kenneth . R Hess, and Apostolia Maria Tsimberidou |
8937-8946 |
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Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition |
https://doi.org/10.18632/oncotarget.2407 Edward Allan R. Sison, Daniel Magoon, Li Li, Colleen E. Annesley, Donald Small, and Patrick Brown |
8947-8958 |
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The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells |
https://doi.org/10.18632/oncotarget.1863 Joseph Mazar, Wei Zhao, Ahmad M. Khalil, Bongyong Lee, John Shelley, Subramaniam S. Govindarajan, Fumiko Yamamoto, Maya Ratnam, Muhammad Nauman Aftab, Sheila Collins, Brian N. Finck, Xianlin Han, John S. Mattick, Marcel E. Dinger, and Ranjan J. Perera |
8959-8969 |
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A novel tumor suppressor function of Kindlin-3 in solid cancer |
https://doi.org/10.18632/oncotarget.2125 Ibtissem Djaafri, Farah Khayati, Suzanne Menashi, Jorg Tost, Marie-Pierre Podgorniak, Aurelie Sadoux, Antoine Daunay, Luis Teixeira, Jean Soulier, Ahmed Idbaih, Niclas Setterblad, Françoise Fauvel, Fabien Calvo, Anne Janin, Celeste Lebbé, and Samia Mourah |
8970-8985 |
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Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth |
https://doi.org/10.18632/oncotarget.1510 Jan Kroon, Lars S. in 't Veld, Jeroen T. Buijs, Henry Cheung, Geertje van der Horst, and Gabri van der Pluijm |
8986-8994 |
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The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model |
https://doi.org/10.18632/oncotarget.2297 Rada Amin, Abdelghafour Marfak, Céline Pangault, Christelle Oblet, Aurélie Chanut, Karin Tarte, Yves Denizot, and Michel Cogné |
8995-9006 |
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A novel calcium-dependent mechanism of acquired resistance to IGF-1 receptor inhibition in prostate cancer cells |
https://doi.org/10.18632/oncotarget.2346 Cale D. Fahrenholtz, Ann M. Greene, Pedro J. Beltran, and Kerry L. Burnstein |
9007-9021 |
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Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways |
https://doi.org/10.18632/oncotarget.2493 Ksenia Lezhnina, Olga Kovalchuk, Alexander A. Zhavoronkov, Mikhail B. Korzinkin, Anastasia A. Zabolotneva, Peter V. Shegay, Dmitry G. Sokov, Nurshat M. Gaifullin, Igor G. Rusakov, Alexander M. Aliper, Sergey A. Roumiantsev, Boris Y. Alekseev, Nikolay M. Borisov, and Anton A. Buzdin |
9022-9032 |
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The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors |
https://doi.org/10.18632/oncotarget.1925 Tun Kiat Ko, Charles T.H. Chuah, John W.J. Huang, King-Pan Ng, and S. Tiong Ong |
9033-9038 |
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Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme |
https://doi.org/10.18632/oncotarget.1996 Xiaohui Yu, Lifang Yang, Murray J. Cairns, Crispin Dass, Edward Saravolac, Xiong Li, and Lun-Quan Sun |
9039-9048 |
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Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer |
https://doi.org/10.18632/oncotarget.2022 Shuying Liu, Xiaolong Meng, Huiqin Chen, Wenbin Liu, Todd Miller, Mandi Murph Yiling Lu, Fan Zhang, Mihai Gagea, Carlos L. Arteaga, Gordon B. Mills, Funda Meric-Bernstam, and Ana M. González-Angulo |
9049-9064 |
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Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma |
https://doi.org/10.18632/oncotarget.2375 Ju-Ae Hwang, Heung-Mo Yang, Doo-Pyo Hong, Sung-Yeon Joo, Yoon-La Choi, Joo-Hung Park, Alexander J. Lazar, Raphael E. Pollock, Dina Lev, and Sung Joo Kim |
9065-9078 |
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Prolactin induces up-regulation of its cognate receptor in breast cancer cells via transcriptional activation of its generic promoter by cross-talk between ERα and STAT5 |
https://doi.org/10.18632/oncotarget.2376 Raghuveer Kavarthapu, Chon-Hwa Tsai Morris, and Maria L. Dufau |
9079-9091 |
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LGR5 promotes the proliferation and tumor formation of cervical cancer cells through the Wnt/β-catenin signaling pathway |
https://doi.org/10.18632/oncotarget.2377 Qing Chen, Hao-Zhe Cao, and Peng-Sheng Zheng |
9092-9105 |
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MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling |
https://doi.org/10.18632/oncotarget.2379 Cen Zhang, Juan Liu, Xiaolong Wang, Rui Wu, Meihua Lin, Saurabh V. Laddha, Qifeng Yang, Chang S. Chan, and Zhaohui Feng |
9106-9117 |
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Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms |
https://doi.org/10.18632/oncotarget.2361 Xin Chen, Xianping Shi, Chong Zhao, Xiaofen Li, Xiaoying Lan, Shouting Liu, Hongbiao Huang, Ningning Liu, Siyan Liao, Dan Zang, Wenbin Song, Quentin Liu, Bing Z. Carter, Ping Q. Dou, Xuejun Wang, and Jinbao Liu |
9118-9132 |
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p70 S6 kinase drives ovarian cancer metastasis through multicellular spheroid-peritoneum interaction and P-cadherin/β1 integrin signaling activation |
https://doi.org/10.18632/oncotarget.2362 Carman Ka Man Ip, Susan Yung, Tak-Mao Chan, Sai-Wah Tsao, and Alice Sze Tsai Wong |
9133-9149 |
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Crizotinib exhibits antitumor activity by targeting ALK signaling not c-MET in pancreatic cancer |
https://doi.org/10.18632/oncotarget.2363 Hong Hua Yan, Kyung Hee Jung, Mi Kwon Son, Zhenghuan Fang, Soo Jung Kim, Ye-Lim Ryu, Juyoung Kim, Mi-Hyun Kim, and Soon-Sun Hong |
9150-9168 |
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Biphasic regulation of autophagy by miR-96 in prostate cancer cells under hypoxia |
https://doi.org/10.18632/oncotarget.2396 Yi Ma, Hao-Zheng Yang, Bai-Jun Dong, Han-Bing Zou, Yan Zhou, Xian-Ming Kong, and Yi-Ran Huang |
9169-9182 |
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Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia |
https://doi.org/10.18632/oncotarget.2399 Shachar Raz, Michal Stark, and Yehuda G. Assaraf |
9183-9198 |
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Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy. |
https://doi.org/10.18632/oncotarget.2374 Elisa Donnard, Paula F. Asprino, Bruna R. Correa, Fabiana Bettoni, Fernanda Koyama, Fabio C. Navarro, Rodrigo O. Perez, John Mariadason, Oliver M. Sieber, Robert L. Straussberg, Andrew J.G. Simpson, Denis L.F. Jardim, Luiz Fernando L. Reis, Raphael B. Parmigiani, Pedro A.F. Galante, and Anamaria A. Camargo |
9199-9213 |
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Vav1 promotes lung cancer growth by instigating tumor-microenvironment cross-talk via growth factor secretion |
https://doi.org/10.18632/oncotarget.2400 Shulamit Sebban, Marganit Farago, Shiran Rabinovich, Galit Lazer, Yulia Idelchuck, Lena Ilan, Eli Pikarsky, and Shulamit Katzav |
9214-9226 |
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Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer |
https://doi.org/10.18632/oncotarget.2402 Jong-Lyel Roh, Eun Hye Kim, Jin Young Park, Ji Won Kim, Minsu Kwon, and Byung-Heon Lee |
9227-9238 |
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Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab |
https://doi.org/10.18632/oncotarget.2409 Rita De Santis, Antonio Rosi, Anna Maria Anastasi, Caterina Chiapparino, Claudio Albertoni, Barbara Leoni, Angela Pelliccia, Daniela Santapaola, Valeria Carollo, Emanuele Marra, Luigi Aurisicchio, Brunilde Arseni, Maria Lucrezia Pacello, Gabriella Palmieri, Simone Battella, Fiorella Petronzelli, and Ferdinando Maria Milazzo |
9239-9255 |
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Rpb3 promotes hepatocellular carcinoma through its N-terminus |
https://doi.org/10.18632/oncotarget.2389 Zhe-Ping Fang, Bei-Ge Jiang, Fa-Biao Zhang, Ai-Dong Wang, Yi-Ming Ji, Ji-Cheng Li, Wei-Ping Zhou, Hai-Xiong Han, and Wei-Jie Zhou |
9256-9268 |
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DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition |
https://doi.org/10.18632/oncotarget.2393 Parthasarathy Chandrakesan, Nathaniel Weygant, Randal May, Dongfeng Qu, Harisha R. Chinthalapally, Sripathi M. Sureban, Naushad Ali, Stan A. Lightfoot, Shahid Umar, and Courtney W. Houchen |
9269-9280 |
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Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC |
https://doi.org/10.18632/oncotarget.2423 Kaihua Zhang, Lamont Jones, Sora Lim, Christopher A. Maher, Douglas Adkins, James Lewis, Randall J. Kimple, Elana J. Fertig, Christine H. Chung, Andreas Herrlich, Matthew J. Ellis, Brian A. Van Tine, and Loren S. Michel |
9281-9294 |
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Combining targeted drugs to overcome and prevent resistance of solid cancers with some stem-like cell features |
https://doi.org/10.18632/oncotarget.2424 Elina Jokinen, Niina Laurila, Peppi Koivunen, and Jussi P. Koivunen |
9295-9307 |
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Multidrug resistance protein 4/ ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia |
https://doi.org/10.18632/oncotarget.2425 Sabrina Copsel, Ariana Bruzzone, Maria May, Julien Beyrath, Victoria Wargon, Jeannette Cany, Frans G.M. Russel, Carina Shayo, and Carlos Davio |
9308-9321 |
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P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment |
https://doi.org/10.18632/oncotarget.2427 Young Nak Joo, Hana Jin, So Young Eun, Sang Won Park, Ki Churl Chang, and Hye Jung Kim |
9322-9334 |
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Androgen deprivation therapy sensitizes prostate cancer cells to T-cell killing through androgen receptor dependent modulation of the apoptotic pathway |
https://doi.org/10.18632/oncotarget.2429 Andressa Ardiani, Sofia R. Gameiro, Anna R. Kwilas, Renee N. Donahue, and James W. Hodge |
9335-9348 |
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Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers |
https://doi.org/10.18632/oncotarget.2430 Wei Guo, Jianjun Lu, Meng Dai, Taihua Wu, Zhenlong Yu, Jingshu Wang, Wangbing Chen, Dingbo Shi, Wendan Yu, Yao Xiao, Canhui Yi, Zhipeng Tang, Tingting Xu, Xiangsheng Xiao, Yuhui Yuan, Quentin Liu, Guangwei Du, and Wuguo Deng |
9349-9361 |
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The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer |
https://doi.org/10.18632/oncotarget.2433 Martin C. Sadowski, Rebecca H. Pouwer, Jennifer H. Gunter, Amy A. Lubik, Ronald J. Quinn, and Colleen C. Nelson |
9362-9381 |
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Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway |
https://doi.org/10.18632/oncotarget.2412 Jun-Bum Park, Sameer Agnihotri, Brian Golbourn, Kelsey C. Bertrand, Amanda Luck, Nesrin Sabha, Christian A. Smith, Sara Byron, Gelareh Zadeh, Sidney Croul, Michael Berens, and James T. Rutka |
9382-9395 |
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The DNA2 nuclease/helicase is an estrogen-dependent gene mutated in breast and ovarian cancers |
https://doi.org/10.18632/oncotarget.2414 Carmit Strauss, Maya Kornowski, Avraham Benvenisty, Amit Shahar, Hadas Masury, Ittai Ben-Porath, Tommer Ravid, Ayelet Arbel-Eden, and Michal Goldberg |
9396-9409 |
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Overexpression of Collagen Triple Helix Repeat Containing 1 (CTHRC1) is associated with tumour aggressiveness and poor prognosis in human non-small cell lung cancer |
https://doi.org/10.18632/oncotarget.2421 Zunfu Ke, Weiling He, Yuanhui Lai, Xuefeng Guo, Sharon Chen, Shuhua Li, Yuefeng Wang, and Liantang Wang |
9410-9424 |
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Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis |
https://doi.org/10.18632/oncotarget.2444 Ryan A. Hlady, Rochelle L. Tiedemann, William Puszyk, Ivan Zendejas, Lewis R. Roberts, Jeong-Hyeon Choi, Chen Liu, and Keith D. Robertson |
9425-9443 |
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miR-524-5p suppresses the growth of oncogenic BRAF melanoma by targeting BRAF and ERK2 |
https://doi.org/10.18632/oncotarget.2452 Szu-Mam Liu, Jean Lu, Hoong-Chien Lee, Feng-Hsiang Chung, and Nianhan Ma |
9444-9459 |
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GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer |
https://doi.org/10.18632/oncotarget.2455 Glen P. Marszalowicz, Adam E. Snook, Michael S. Magee, Dante Merlino, Lisa D. Berman-Booty, and Scott A. Waldman |
9460-9471 |
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miR-382 inhibits tumor growth and enhance chemosensitivity in osteosarcoma |
https://doi.org/10.18632/oncotarget.2418 Meng Xu, Hua Jin, Cheng-Xiong Xu, Bo Sun, Zhi Mao, Wen-Zhi Bi, and Yan Wang |
9472-9483 |
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What makes a blood cell based miRNA expression pattern disease specific? - A miRNome analysis of blood cell subsets in lung cancer patients and healthy controls |
https://doi.org/10.18632/oncotarget.2419 Petra Leidinger, Christina Backes, Indra N. Dahmke, Valentina Galata, Hanno Huwer, Ingo Stehle, Robert Bals, Andreas Keller, and Eckart Meese |
9484-9497 |
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TOP2Ahigh is the phenotype of recurrence and metastasis whereas TOP2Aneg cells represent cancer stem cells in prostate cancer |
https://doi.org/10.18632/oncotarget.2411 Xuefeng Li, Yunying Liu, Wenqi Chen, Yuxiang Fang, Huiming Xu, HelenHe Zhu, Mingliang Chu, Wang Li, Guanglei Zhuang, and Wei-Qiang Gao |
9498-9513 |
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FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells |
https://doi.org/10.18632/oncotarget.2413 Hong-Jian Wei, Wen-Cheng Lo, Jac A. Nickoloff, Wei-Hong Chen, Hen-Yu Liu, Ya-Ting Chang, Pan-Chyr Yang, Cheng-Wen Wu, David F. Williams, Juri G. Gelovani, and Win-Ping Deng |
9514-9529 |
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