Oncotarget
Wild-type p110α has more interactions with the nSH2 domain than the oncogenic mutant H1047R. See Gabelli et. al.
Immunogenic cell death inducers as anticancer agents |
https://doi.org/10.18632/oncotarget.2266 Oliver Kepp, Laura Senovilla, and Guido Kroemer |
5190-5191 |
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Targeting lemurs against cancer metastasis |
https://doi.org/10.18632/oncotarget.2271 Yichen Xu, Hua Zhang, and Georgios Giamas |
5192-5193 |
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Ras in epidermal proliferation |
https://doi.org/10.18632/oncotarget.2275 Matthias Drosten, Carmen G. Lechuga, and Mariano Barbacid |
5194-5195 |
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Knowledge-based computational models |
https://doi.org/10.18632/oncotarget.2276 Wim Verhaegh, and Anja van de Stolpe |
5196-5197 |
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Structural basis of nSH2 regulation and lipid binding in PI3Kα |
https://doi.org/10.18632/oncotarget.2263 Michelle S. Miller, Oleg Schmidt-Kittler, David M. Bolduc, Evan T. Brower, Daniele Chaves-Moreira, Marc Allaire, Kenneth W. Kinzler, Ian G. Jennings, Philip E. Thompson, Philip A. Cole, L. Mario Amzel, Bert Vogelstein, and Sandra B. Gabelli |
5198-5208 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
NY-ESO-1 as a potential immunotherapeutic target in renal cell carcinoma |
https://doi.org/10.18632/oncotarget.2101 Eva Giesen, Lucia B. Jilaveanu, Fabio Parisi, Yuval Kluger, Robert L. Camp, and Harriet M. Kluger |
5209-5217 |
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An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine |
https://doi.org/10.18632/oncotarget.2129 Leonel Maldonado, Mariana Brait, Christina Michailidi, Enrico Munari, Tina Driscoll, Luciana Schultz, Trinity Bivalacqua, Mark Schoenberg, David Sidransky, George J. Netto, and Mohammad Obaidul Hoque |
5218-5233 |
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Low PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome |
https://doi.org/10.18632/oncotarget.2062 Gloria Milani, Paola Rebora, Benedetta Accordi, Luisa Galla, Silvia Bresolin, Gianni Cazzaniga, Barbara Buldini, Rossella Mura, Saverio Ladogana, Eugenia Giraldi, Valentino Conter, Geertruy Te Kronnie, Maria Grazia Valsecchi, and Giuseppe Basso |
5234-5245 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
High circulating hepatocyte growth factor levels associate with epithelial to mesenchymal transition and poor outcome in small cell lung cancer patients |
https://doi.org/10.18632/oncotarget.2124 Israel Cañadas, Álvaro Taus, Iria González, Xavier Villanueva, Javier Gimeno, Lara Pijuan, Manuel Dómine, Albert Sánchez-Font, Ivan Vollmer, Silvia Menéndez, Oriol Arpí, Sergi Mojal, Federico Rojo, Ana Rovira, Joan Albanell, and Edurne Arriola |
5246-5256 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia |
https://doi.org/10.18632/oncotarget.2072 Jochen J. Frietsch, Carolin Kastner, Thomas G. P. Grunewald, Hardy Schweigel, Peter Nollau, Janine Ziermann, Joachim H. Clement, Paul La Rosée, Andreas Hochhaus, and Elke Butt |
5257-5271 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
CD271 is an imperfect marker for melanoma initiating cells |
https://doi.org/10.18632/oncotarget.1967 Yann Cheli, Vanessa F. Bonnazi, Arnaud Jacquel, Maryline Allegra, Gian Marco De Donatis, Philippe Bahadoran, Corine Bertolotto, and Robert Ballotti |
5272-5283 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Circulating miR-148b and miR-133a as biomarkers for breast cancer detection |
https://doi.org/10.18632/oncotarget.2014 Jie Shen, Qiang Hu, Michael Schrauder, Li Yan, Dan Wang, Leonardo Medico, Yuqing Guo, Song Yao, Qianqian Zhu, Biao Liu, Maochun Qin, Matthias W. Beckmann, Peter A. Fasching, Reiner Strick, Candace S. Johnson, Christine B. Ambrosone, Hua Zhao, and Song Liu |
5284-5294 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Loss of ARID1A expression sensitizes cancer cells to PI3K- and AKT-inhibition |
https://doi.org/10.18632/oncotarget.2092 Eleftherios P. Samartzis, Katrin Gutsche, Konstantin J. Dedes, Daniel Fink, Manuel Stucki, and Patrick Imesch |
5295-5303 |
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A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy |
https://doi.org/10.18632/oncotarget.2093 Marc Turini, Patrick Chames, Pierre Bruhns, Daniel Baty, and Brigitte Kerfelec |
5304-5319 |
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Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration |
https://doi.org/10.18632/oncotarget.2097 Christina A. von Roemeling, Laura A. Marlow, Derek C. Radisky, Austin Rohl, Hege E. Larsen, Johnny Wei, Heather Sasinowska, Heng Zhu, Richard Drake, Maciek Sasinowski, Han W. Tun, and John A. Copland |
5320-5334 |
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Galectin-4 expression is associated with reduced lymph node metastasis and modulation of Wnt/β-catenin signalling in pancreatic adenocarcinoma |
https://doi.org/10.18632/oncotarget.2104 Mina Maftouh, Ana I. Belo, Amir Avan, Niccola Funel, Godefridus J. Peters, Elisa Giovannetti, and Irma van Die |
5335-5349 |
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Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin |
https://doi.org/10.18632/oncotarget.2110 Chakrapani Tripathi, Brij Nath Tewari, Ranjana Kumari Kanchan, Khemraj Singh Baghel, Naveen Nautiyal, Richa Shrivastava, Harbeer Kaur, Madan Lal Bramha Bhatt, and Smrati Bhadauria |
5350-5368 |
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GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the β-catenin signaling |
https://doi.org/10.18632/oncotarget.2105 Zongwei Li, Yingying Wang, Haili Wu, Lichao Zhang, Peng Yang, and Zhuoyu Li |
5369-5380 |
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Combined therapy with RAD001 e BEZ235 overcomes resistance of PET immortalized cell lines to mTOR inhibition |
https://doi.org/10.18632/oncotarget.2111 Ilaria Passacantilli, Gabriele Capurso, Livia Archibugi, Sara Calabretta, Sara Caldarola, Fabrizio Loreni, Gianfranco Delle Fave, and Claudio Sette |
5381-5391 |
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FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma |
https://doi.org/10.18632/oncotarget.2107 Linka Xie, Olga Ritz, Frank Leithäuser, Hanfeng Guan, Johanna Färbinger, Clarissa D. Weitzer, Franziska Gehringer, Silke Brüderlein, Karlheinz Holzmann, Marion J. Vogel, Peter Möller, Thomas Wirth, and Alexey Ushmorov |
5392-5402 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Tumor suppressor XAF1 induces apoptosis, inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma |
https://doi.org/10.18632/oncotarget.2114 Li Ming Zhu, Dong Mei Shi, Qiang Dai, Xiao Jiao Cheng, Wei Yan Yao, Ping Hu Sun, Yan Fei Ding, Min Min Qiao, Yun Lin Wu, Shi Hu Jiang, and Shui Ping Tu |
5403-5415 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma |
https://doi.org/10.18632/oncotarget.2116 Lin Wang, Zhu-mei Shi, Cheng-fei Jiang, Xue Liu, Qiu-dan Chen, Xu Qian, Dong-mei Li, Xin Ge, Xie-feng Wang, Ling-Zhi Liu, Yong-ping You, Ning Liu, and Bing-Hua Jiang |
5416-5427 |
Abstract | PDF | HTML | How to cite | Order a Reprint |
The response of head and neck squamous cell carcinoma to cetuximab treatment depends on Aurora kinase A polymorphism |
https://doi.org/10.18632/oncotarget.2117 Anja Pickhard, Michael Siegl, Alexander Baumann, Maximilian Huhn, Markus Wirth, Rudolf Reiter, Martina Rudelius, Guido Piontek, and Gero Brockhoff |
5428-5438 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma |
https://doi.org/10.18632/oncotarget.2118 Shu-biao Ye, Ze-Lei Li, Dong-hua Luo, Bi-jun Huang, Yu-Suan Chen, Xiao-shi Zhang, Jun Cui, Yi-xin Zeng, and Jiang Li |
5439-5452 |
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Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth |
https://doi.org/10.18632/oncotarget.2113 Ningning Liu, Xiaofen Li, Hongbiao Huang, Chong Zhao, Siyan Liao, Changshan Yang, Shouting Liu, Wenbin Song, Xiaoyu Lu, Xiaoying Lan, Xin Chen, Songgang Yi, Li Xu, Lili Jiang, Canguo Zhao, Xiaoxian Dong, Ping Zhou, Shujue Li, Shunqing Wang, Xianping Shi, Ping Q. Dou, Xuejun Wang, and Jinbao Liu |
5453-5471 |
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Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes |
https://doi.org/10.18632/oncotarget.2121 Barbara Chiavarina, Marie-Julie Nokin, Florence x Florence Durieux, Elettra Bianchi, Andrei x Andrei Turtoi, Olivier Peulen, Paul Peixoto, Philippe Irigaray, Koji Uchida, Dominique Belpomme, Philippe Delvenne, Vincent Castronovo, and Akeila Bellahcène |
5472-5482 |
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Hedgehog signaling sensitizes Glioma stem cells to endogenous nano-irradiation |
https://doi.org/10.18632/oncotarget.2123 Agnieszka Morgenroth, Andreas T. J. Vogg, Katja Ermert, Boris Zlatopolskiy, and Felix M. Mottaghy |
5483-5493 |
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A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis |
https://doi.org/10.18632/oncotarget.2131 Na Shen, Fei Yan, Jiuxia Pang, Lai-Chu Wu, Aref Al-Kali, Mark R. Litzow, and Shujun Liu |
5494-5509 |
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Sustained conditional knockdown reveals intracellular bone sialoprotein as essential for breast cancer skeletal metastasis |
https://doi.org/10.18632/oncotarget.2132 Marineta Kovacheva, Michael Zepp, Stefan M. Berger, and Martin R. Berger |
5510-5522 |
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Sensitization of radio-resistant prostate cancer cells with a unique cytolethal distending toxin |
https://doi.org/10.18632/oncotarget.2133 Chih-Ho Lai, Chia-Shuo Chang, Hsin-Ho Liu, Yuh-Shyan Tsai, Feng-Ming Hsu, Yung-Luen Yu, Cheng-Kuo Lai, Leah Gandee, Rey-Chen Pong, Heng-Wei Hsu, Lan Yu, Debabrata Saha, and Jer-Tsong Hsieh |
5523-5534 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD |
https://doi.org/10.18632/oncotarget.2137 Cen Zhang, Juan Liu, Rui Wu, Yingjian Liang, Meihua Lin, Jia Liu, Chang S. Chan, Wenwei Hu, and Zhaohui Feng |
5535-5546 |
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Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model |
https://doi.org/10.18632/oncotarget.2139 Juozas Vasiliauskas, Madison A. Nashu, Peterson Pathrose, Sandra L. Starnes, and Susan E. Waltz |
5547-5558 |
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Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway |
https://doi.org/10.18632/oncotarget.2140 Harish Potu, Luke F. Peterson, Anupama Pal, Monique Verhaegen, Juxiang Cao, Moshe Talpaz, and Nicholas J. Donato |
5559-5569 |
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Small interfering RNA (siRNA)-mediated knockdown of macrophage migration inhibitory factor (MIF) suppressed cyclin D1 expression and hepatocellular carcinoma cell proliferation |
https://doi.org/10.18632/oncotarget.2141 Xiao-hui Huang, Wei-hua Jian, Zhao-feng Wu, Jie Zhao, Hua Wang, Wen Li, and Jin-tang Xia |
5570-5580 |
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Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA |
https://doi.org/10.18632/oncotarget.2143 Motoko Ohno, Motoyuki Otsuka, Takahiro Kishikawa, Chikako Shibata, Takeshi Yoshikawa, Akemi Takata, Ryosuke Muroyama, Norie Kowatari, Masaya Sato, Naoya Kato, Shun'ichi Kuroda, and Kazuhiko Koike |
5581-5590 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
E3-ligase Skp2 predicts poor prognosis and maintains cancer stem cell pool in nasopharyngeal carcinoma |
https://doi.org/10.18632/oncotarget.2149 Jing Wang, Ying Huang, Zhong Guan, Jia-liang Zhang, Hong-kai Su, Wei Zhang, Cai-feng Yue, Min Yan, Su Guan, and Quentin Qiang Liu |
5591-5601 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma |
https://doi.org/10.18632/oncotarget.2136 Junmou Hong, Zhenguo Liu, Hua zhu, Xin Zhang, Yongju Liang, Shiyuan Yao, Fang Wang, Xiaoyun xie, Bo Zhang, Tao Tan, Liwu Fu, Jing Nie, and Chao Cheng |
5602-5614 |
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Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter |
https://doi.org/10.18632/oncotarget.2151 Ho Kyung Seo, Jeong Bin Seo, Jae-Kook Nam, Kyung-Chae Jeong, Seung-Pil Shin Shin, In-Hoo Kim, Sang Don Lee, and Sang-Jin Lee |
5615-5623 |
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Upregulation of microRNA135a-3p and death receptor 5 plays a critical role in Tanshinone I sensitized prostate cancer cells to TRAIL induced apoptosis |
https://doi.org/10.18632/oncotarget.2152 Eun Ah Shin, Eun Jung Sohn, Gunho Won, Jeong-Un Choi, Myongsuk Jeong, Bonglee Kim, Min-Jeong Kim, and Sung-Hoon Kim |
5624-5636 |
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Histone deacetylase inhibitor treatment induces ‘BRCAness’ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells |
https://doi.org/10.18632/oncotarget.2154 Kyungsoo Ha, Warren Fiskus, Dong Soon Choi, Srividya Bhaskara, Leandro Cerchietti, Santhana G. T. Devaraj, Bhavin Shah, Sunil Sharma, Jenny C. Chang, Ari M. Melnick, Scott Hiebert, and Kapil N. Bhalla |
5637-5650 |
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A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCδ and E-cadherin |
https://doi.org/10.18632/oncotarget.2155 Li-Ting Wang, Jing-Ping Liou, Yu-Hsuan Li, Yi-Min Liu, Shiow-Lin Pan, and Che-Ming Teng |
5651-5662 |
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TFF1 activates p53 through down-regulation of miR-504 in gastric cancer |
https://doi.org/10.18632/oncotarget.2156 Mohammed Soutto, Zheng Chen, Mohamed A. Saleh, Ahmed Katsha, Shoumin Zhu, Alexander Zaika, Abbes Belkhiri, and Wael El-Rifai |
5663-5673 |
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Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970 |
https://doi.org/10.18632/oncotarget.2158 Amy B. Hall, Dave Newsome, Yuxin Wang, Diane M. Boucher, Brenda Eustace, Yong Gu, Brian Hare, Mac A. Johnson, Howard Li, Sean Milton, Cheryl E. Murphy, Darin Takemoto, Crystal Tolman, Mark Wood, Peter Charlton, Jean-Damien Charrier, Brinley Furey, Julian Golec, Philip M. Reaper, and John R. Pollard |
5674-5685 |
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Multiple myeloma cell-derived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation |
https://doi.org/10.18632/oncotarget.2159 Bonnie K. Arendt, Denise K. Walters, Xiaosheng Wu, Renee C. Tschumper, and Diane F. Jelinek |
5686-5699 |
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Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-β/Smad signaling pathway |
https://doi.org/10.18632/oncotarget.2144 Jiang Geng, Jie Fan, Qi Ouyang, Xiaopeng Zhang, Xiaolong Zhang, Juan Yu, Zude Xu, Qianyu Li, Xudong Yao, Xiuping Liu, and Junhua Zheng |
5700-5711 |
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FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation |
https://doi.org/10.18632/oncotarget.2145 Luca Ferrari, Anna Pistocchi, Laura Libera, Nicola Boari, Pietro Mortini, Gianfranco Bellipanni, Antonio Giordano, Franco Cotelli, and Paola Riva |
5712-5724 |
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Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133 |
https://doi.org/10.18632/oncotarget.2167 Stella Chai, Man Tong, Kai Yu Ng, Pak Shing Kwan, Yuen Piu Chan, Tsun Ming Fung, Terence K. Lee, Nathalie Wong, Dan Xie, Yun-Fei Yuan, Xin-Yuan Guan, and Stephanie Ma |
5725-5735 |
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H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC |
https://doi.org/10.18632/oncotarget.2169 Marianeve Carotenuto, Pasqualino De Antonellis, Lucia Liguori, Giovanna Benvenuto, Daniela Magliulo, Alessandro Alonzi, Cecilia Turino, Carmela Attanasio, Valentina Damiani, Anna Maria Bello, Fabiana Vitiello, Rosa Pasquinelli, Luigi Terracciano, Antonella Federico, Alfredo Fusco, Jamie Freeman, Trevor C. Dale, Charles Decraene, Gennaro Chiappetta, Francovito Piantedosi, Cecilia Calabrese, and Massimo Zollo |
5736-5749 |
Abstract | PDF | HTML | Supplementary Information | How to cite | Order a Reprint |
The ALK inhibitor ASP3026 eradicates NPM-ALK+ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model |
https://doi.org/10.18632/oncotarget.2170 Suraj Konnath George, Deeksha Vishwamitra, Roxsan Manshouri, Ping Shi, and Hesham M. Amin |
5750-5763 |
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Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era |
https://doi.org/10.18632/oncotarget.2180 Christina Perry, Devika Agarwal, Tarek M. A. Abdel-Fatah, Anbarasu Lourdusamy, Richard Grundy, Dorothee T. Auer, David Walker, Ravi Lakhani, Ian S. Scott, Stephen Chan, Graham Ball, and Srinivasan Madhusudan |
5764-5781 |
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Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma |
https://doi.org/10.18632/oncotarget.2164 Aparna Jayachandran, Matthew Anaka, Prashanth Prithviraj, Christopher Hudson, Sonja J. McKeown, Pu-Han Lo, Laura J. Vella, Colin R. Goding, Jonathan Cebon, and Andreas Behren |
5782-5797 |
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Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells |
https://doi.org/10.18632/oncotarget.2185 Xiuming Liang, Jiping Zeng, Lixiang Wang, Li Shen, Shuyan Li, Lin Ma, Xinyu Ci, Jingya Yu, Mutian Jia, Yundong Sun, Zhifang Liu, Shili Liu, Wenjuan Li, Han Yu, Chunyan Chen, and Jihui Jia |
5798-5807 |
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Oncogene-mediated regulation of p53 ISGylation and functions |
https://doi.org/10.18632/oncotarget.2199 Yi-Fu Huang, and Dmitry V. Bulavin |
5808-5818 |
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Novel celastrol derivatives inhibit the growth of hepatocellular carcinoma patient-derived xenografts |
https://doi.org/10.18632/oncotarget.2171 Wei Wei, Song Wu, Xiaolin Wang, Chris Kin-Wai Sun, Xiaoyang Yang, Xinrui Yan, Mei-Sze Chua, and Samuel So |
5819-5831 |
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HERG1 functions as an oncogene in pancreatic cancer and is downregulated by miR-96 |
https://doi.org/10.18632/oncotarget.2200 Jin Feng, Junbo Yu, Xiaolin Pan, Zengliang Li, Zheng Chen, Wenjie Zhang, Bin Wang, Li Yang, Hao Xu, Guoxin Zhang, and Zekuan Xu |
5832-5844 |
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Caspase-2 regulates oncogene-induced senescence |
https://doi.org/10.18632/oncotarget.2286 Delphine Gitenay, Hélène Lallet-Daher, and David Bernard |
5845-5847 |
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