Oncotarget
Conjugation of human IL-12 to a DNA/histone-binding antibody increases its half-life and attenuates its ability to stimulate IFN-gamma production. Figure 1 (A) shows a ribbon diagram of NHS-IL12, an immunocytokine consisting of the NHS76 antibody fused to 2 IL-12p70 heterodimers. See Fallon et al.
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Pathways and therapeutic targets in melanoma |
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TERT promoter mutations in renal cell carcinomas and upper tract urothelial carcinomas |
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MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit |
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ΔNp63 isoform-mediated β-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma |
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The immunocytokine NHS-IL12 as a potential cancer therapeutic |
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https://doi.org/10.18632/oncotarget.1871 Lei Hu, Yan-tao Duan, Jian-fang Li, Li-ping Su, Min Yan, Zheng-gang Zhu, Bing-ya Liu, and Qiu-meng Yang |
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γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model |
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Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another “double hit” lymphoma with very poor outcome? |
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Discovery and validation of an INflammatory PROtein-driven GAstric cancer Signature (INPROGAS) using antibody microarray-based oncoproteomics |
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A new mosaic pattern in glioma vascularization: exogenous endothelial progenitor cells integrating into the vessels containing tumor-derived endothelial cells |
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Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach |
https://doi.org/10.18632/oncotarget.1898 Chandra K. Singh, Jasmine George, Minakshi Nihal, Grzegorz Sabat, Raj Kumar, and Nihal Ahmad |
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