Oncotarget

Vol 9, No 43

June 5, 2018

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About The Cover

The cover for issue 43 of Oncotarget features Figure 2A, "Silencing GLI1 influences GBM cell response to TMZ and reduces multidrug efflux activity," by Melamed, et al.

Table of Contents

Research Papers

Optimization of cervical lymph node clinical target volume delineation in nasopharyngeal carcinoma: a single center experience and recommendation

Optimization of cervical lymph node clinical target volume delineation in nasopharyngeal carcinoma: a single center experience and recommendation

https://doi.org/10.18632/oncotarget.23723

Li Li, Yi Li, Jun Zhang, Qiuji Wu, Haijun Yu, Zheng Li, Conghua Xie, Yunfeng Zhou,  and Yahua Zhong
26980-26989
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Quality of life in cancer patients undergoing anticoagulant treatment with LMWH for venous thromboembolism: the QUAVITEC study on behalf of the Groupe Francophone Thrombose et Cancer (GFTC)

Quality of life in cancer patients undergoing anticoagulant treatment with LMWH for venous thromboembolism: the QUAVITEC study on behalf of the Groupe Francophone Thrombose et Cancer (GFTC)

https://doi.org/10.18632/oncotarget.25454

Dominique Farge, Francis Cajfinger, Nicolas Falvo, Toufek Berremili, Francis Couturaud, Okba Bensaoula, Lionel Védrine, Hocine Bensalha, Isabelle Bonnet, Denis Péré-Vergé, Marie Coudurier, Veronique Li, Hanadi Rafii, Ilham Benzidia, Jean M. Connors,  and Matthieu Resche-Rigon
26990-26999
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Investigating the role of Hedgehog/GLI1 signaling in glioblastoma cell response to temozolomide

Investigating the role of Hedgehog/GLI1 signaling in glioblastoma cell response to temozolomide

https://doi.org/10.18632/oncotarget.25467

Jilian R. Melamed, Joshua T. Morgan, Stephen A. Ioele, Jason P. Gleghorn, Jennifer Sims-Mourtada,  and Emily S. Day
27000-27015
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KCTD12 is negatively regulated by Kit in gastrointestinal stromal tumors

KCTD12 is negatively regulated by Kit in gastrointestinal stromal tumors

https://doi.org/10.18632/oncotarget.25469

Yoshiyuki Suehara, Keisuke Akaike, Kenta Mukaihara, Aiko Kurisaki-Arakawa, Daisuke Kubota, Taketo Okubo, Hiroyuki Mitomi, Keiko Mitani, Michiko Takahashi, Midori Toda-Ishii, Youngji Kim, Yu Tanabe, Tatsuya Takagi, Takuo Hayashi, Kaoru Mogushi, Kazuo Kaneko, Takashi Yao,  and Tsuyoshi Saito
27016-27026
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Serum levels of soluble urokinase plasminogen activator receptor (suPAR) predict outcome after resection of colorectal liver metastases

Serum levels of soluble urokinase plasminogen activator receptor (suPAR) predict outcome after resection of colorectal liver metastases

https://doi.org/10.18632/oncotarget.25471

Sven H. Loosen, Frank Tacke, Marcel Binnebosel, Catherine Leyh, Mihael Vucur, Florian Heitkamp, Wenzel Schoening, Tom F. Ulmer, Patrick H. Alizai, Christian Trautwein, Alexander Koch, Thomas Longerich, Christoph Roderburg, Ulf P. Neumann,  and Tom Luedde
27027-27038
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Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine kinase inhibitors

Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.25472

Meriem Sarah Mekki, Alexandra Mougel, Audrey Vinchent, Charlotte Paquet, Marie-Christine Copin, Catherine Leroy, Zoulika Kherrouche, Jean-Paul Bonte, Oleg Melnyk, Jérôme Vicogne,  and David Tulasne
27039-27058
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LRP/LR specific antibody IgG1-iS18 impedes neurodegeneration in Alzheimer's disease mice

LRP/LR specific antibody IgG1-iS18 impedes neurodegeneration in Alzheimer's disease mice

https://doi.org/10.18632/oncotarget.25473

Eloise Ferreira, Monique J. Bignoux, Tyrone C. Otgaar, Nicolas Tagliatti, Katarina Jovanovic, Boitelo T. Letsolo,  and Stefan F.T. Weiss
27059-27073
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Monitoring EGFR-T790M mutation in serum/plasma for prediction of response to third-generation EGFR inhibitors in patients with lung cancer

Monitoring EGFR-T790M mutation in serum/plasma for prediction of response to third-generation EGFR inhibitors in patients with lung cancer

https://doi.org/10.18632/oncotarget.25478

Teresa Morán, Eudald Felip, Joaquim Bosch-Barrera, Itziar de Aguirre, Jose Luis Ramirez, Carles Mesia, Enric Carcereny, Diana Roa, Elia Sais, Yolanda García, Remei Blanco, Silvia Sanchez, Claudia Rosa Villacorta, Cristina Queralt, Jose María Velarde,  and Rafael Rosell
27074-27086
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Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines

Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines

https://doi.org/10.18632/oncotarget.25484

Helin Feng, Heather Tillman, Gang Wu, Andrew M. Davidoff,  and Jun Yang
27087-27091
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Favorable prognostic role of tropomodulins in neuroblastoma

Favorable prognostic role of tropomodulins in neuroblastoma

https://doi.org/10.18632/oncotarget.25491

Paola Bettinsoli, Giulia Ferrari-Toninelli, Sara Anna Bonini, Michela Guarienti, Davide Cangelosi, Luigi Varesio,  and Maurizio Memo
27092-27103
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The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer

The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer

https://doi.org/10.18632/oncotarget.25497

Jonathan P. Evans, Boleslaw K. Winiarski, Paul A. Sutton, Robert P. Jones, Lorenzo Ressel, Carrie A. Duckworth, Mark D. Pritchard, Zhi-Xiu Lin, Fretwell L. Vicky, Elizabeth M. Tweedle, Eithne Costello, Christopher E. Goldring, Ian M. Copple, Kevin B. Park, Daniel H. Palmer,  and Neil R. Kitteringham
27104-27116
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reduced vasorin enhances angiotensin II signaling within the aging arterial wall

Reduced vasorin enhances angiotensin II signaling within the aging arterial wall

https://doi.org/10.18632/oncotarget.25499

Gianfranco Pintus, Roberta Giordo, Yushi Wang, Wanqu Zhu, Soo Hyuk Kim, Li Zhang, Leng Ni, Jing Zhang, Richard Telljohann, Kimberly R. McGraw, Robert E. Monticone, Chloe Ferris, Lijuan Liu, Mingyi Wang,  and Edward G. Lakatta
27117-27132
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Global metabolite profiling analysis of lipotoxicity in HER2/neu-positive breast cancer cells

Global metabolite profiling analysis of lipotoxicity in HER2/neu-positive breast cancer cells

https://doi.org/10.18632/oncotarget.25500

Jan Baumann, Mostafa Kokabee, Jason Wong, Rakshika Balasubramaniyam, Yan Sun,  and Douglas S. Conklin
27133-27150
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Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells

Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells

https://doi.org/10.18632/oncotarget.25502

Aina Bernal, Marc Moltó-Abad, Daniel Domínguez,  and Laura Tusell
27151-27170
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients

Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients

https://doi.org/10.18632/oncotarget.25506

Ali Abouelghar, Reem Hasnah, Ghina Taouk, Mohamad Saad,  and Manale Karam
27171-27196
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WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3 cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling

WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3 cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling

https://doi.org/10.18632/oncotarget.25509

Wanyin Chen, Leonel Nguekeu Zebaze, Jihu Dong, Laëtitia Chézeau, Perrine Inquimbert, Sylvain Hugel, Songlin Niu, Fréderic Bihel, Emmanuel Boutant, Eléonore Réal, Pascal Villa, Marie-Pierre Junier, Hervé Chneiweiss, Marcel Hibert, Jacques Haiech, Marie-Claude Kilhoffer,  and Maria Zeniou
27197-27219
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Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance

Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance

https://doi.org/10.18632/oncotarget.25513

Augustin Le Naour, Renaud Mevel, Benoit Thibault, Elise Courtais, Elodie Chantalat, Jean Pierre Delord, Bettina Couderc, Julie Guillermet-Guibert,  and Alejandra Martinez
27220-27232
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Construction and characterization of a new TRAIL soluble form, active at picomolar concentrations

Construction and characterization of a new TRAIL soluble form, active at picomolar concentrations

https://doi.org/10.18632/oncotarget.25519

Matias Eliseo Melendez, Renato José Silva-Oliveira, Anna Luiza Silva Almeida Vicente, Lidia Maria Rebolho Batista Arantes, Ana Carolina de Carvalho, Alberto Luis Epstein, Rui Manuel Reis,  and André Lopes Carvalho
27233-27241
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Overcoming drug-tolerant cancer cell subpopulations showing AXL activation and epithelial–mesenchymal transition is critical in conquering ALK-positive lung cancer

Overcoming drug-tolerant cancer cell subpopulations showing AXL activation and epithelial–mesenchymal transition is critical in conquering ALK-positive lung cancer

https://doi.org/10.18632/oncotarget.25531

Shinji Nakamichi, Masahiro Seike, Akihiko Miyanaga, Mika Chiba, Fenfei Zou, Akiko Takahashi, Arimi Ishikawa, Shinobu Kunugi, Rintaro Noro, Kaoru Kubota,  and Akihiko Gemma
27242-27255
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Extensive screening of microRNA populations identifies hsa-miR-375 and hsa-miR-133a-3p as selective markers for human rectal and colon cancer

Extensive screening of microRNA populations identifies hsa-miR-375 and hsa-miR-133a-3p as selective markers for human rectal and colon cancer

https://doi.org/10.18632/oncotarget.25535

David Weber, Laurence Amar, Daniel Gödde,  and Christian Prinz
27256-27267
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells

Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells

https://doi.org/10.18632/oncotarget.25545

Alina D. Nikotina, Lidia Koludarova, Elena Y. Komarova, Elena R. Mikhaylova, Nikolay D. Aksenov, Roman Suezov, Viktor G. Kartzev, Boris A. Margulis,  and Irina V. Guzhova
27268-27279
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Butyrate decreases its own oxidation in colorectal cancer cells through inhibition of histone deacetylases

Butyrate decreases its own oxidation in colorectal cancer cells through inhibition of histone deacetylases

https://doi.org/10.18632/oncotarget.25546

Anna Han, Natalie Bennett, Bettaieb Ahmed, Jay Whelan,  and Dallas R. Donohoe
27280-27292
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Role of WNT5A receptors FZD5 and RYK in prostate cancer cells

Role of WNT5A receptors FZD5 and RYK in prostate cancer cells

https://doi.org/10.18632/oncotarget.25551

Stefanie Thiele, Ariane Zimmer, Andy Göbel, Tilman D. Rachner, Sandra Rother, Susanne Fuessel, Michael Froehner, Manfred P. Wirth, Michael H. Muders, Gustavo B. Baretton, Franz Jakob, Martina Rauner,  and Lorenz C. Hofbauer
27293-27304
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Increased circulating CD4+FOXP3+ T cells associate with early relapse following autologous hematopoietic stem cell transplantation in multiple myeloma patients

Increased circulating CD4+FOXP3+ T cells associate with early relapse following autologous hematopoietic stem cell transplantation in multiple myeloma patients

https://doi.org/10.18632/oncotarget.25553

Egor V. Batorov, Marina A. Tikhonova, Natalia V. Pronkina, Irina V. Kryuchkova, Vera V. Sergeevicheva, Svetlana A. Sizikova, Galina Y. Ushakova, Tatiana A. Aristova, Dariya S. Batorova, Elena V. Menyaeva, Andrey V. Gilevich, Ekaterina Y. Shevela, Alexander A. Ostanin,  and Elena R. Chernykh
27305-27317
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Corrections

Correction: Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia

Correction: Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia

https://doi.org/10.18632/oncotarget.25620

Aimin Qiao, Kuansong Wang, Yunsheng Yuan, Yidi Guan, Xingcong Ren, Lanya Li, Xisha Chen, Feng Li, Alex F. Chen, Jianda Zhou, Jin-Ming Yang,  and Yan Cheng
27318-27318
Correction  |  PDF


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