The Oncosearch | Oncotarget

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Kelsey E. Huntington, Anna Louie, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 11, 2021 · Vol. 12, No. 20 · pp. 1980-1991

Keywords: cytokine profiling, inflammatory response, chemokine, growth factor, immune profiling

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Arvin Medhat, Alla Arzumanyan, Mark A. Feitelson

Published Sep 11, 2021 · Vol. 12, No. 24 · pp. 2421-2433

Keywords: chronic liver disease, hepatocellular carcinoma, HBx, functional cure, epigenetic

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Subotheni Thavaneswaran, Mandy Ballinger, Phyllis Butow, Bettina Meiser, David Goldstein, Frank Lin, Christine Napier, David Thomas, Megan Best

Published Sep 9, 2021 · Vol. 12, No. 21 · pp. 2169-2176

Keywords: comprehensive genomic profiling, precision medicine, targeted treatment selection using genomics, communication, clinicians' experiences with utilising genomic findings in a pan-cancer setting to inform treatment selection

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Nicholas Cho, Sooah Ko, Monica Shokeen

Published Sep 7, 2021 · Vol. 12, No. 20 · pp. 2039-2050

Keywords: near-infrared (NIR) fluorescence, multiple myeloma (MM), cluster of differentiation 38 (CD38), antibody-drug conjugate (ADC), small animal optical imaging

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl, Kristian K. Starheim

Published Sep 4, 2021 · Vol. 12, No. 21 · pp. 2158-2168

Keywords: multiple myeloma, TAK1, apoptosis, NF-κB, cancer treatment

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Angeliki Andrikopoulou, Evangelos Terpos, Spyridoula Chatzinikolaou, Kleoniki Apostolidou, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Meletios-Athanasios Dimopoulos, Flora Zagouri

Published Sep 2, 2021 · Vol. 12, No. 21 · pp. 2206-2214

Keywords: TP53 mutations, next-generation sequencing, biomarker, prognosis, breast cancer

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa, Sônia Nair Báo

Published Aug 27, 2021 · Vol. 12, No. 19 · pp. 1920-1936

Keywords: KIF11 inhibition, Kinesin Eg5, breast cancer, adjuvant treatment, cancer progression

Correction: MicroRNA-126 inhibits tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression Correction

Ming-Hua Hu, Chen-Yang Ma, Xiao-Ming Wang, Chen-Dong Ye, Guang-Xian Zhang, Lin Chen, Jin-Guo Wang

Published Aug 25, 2021 · Vol. 12, No. 18 · pp. 1859-1860

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Adam S. Kittai, Olga V. Danilova, Vi Lam, Tingting Liu, Nur Bruss, Scott Best, Guang Fan, Alexey V. Danilov

Published Aug 23, 2021 · Vol. 12, No. 20 · pp. 2068-2074

Keywords: pevonedistat, T-cell lymphoma, chromosomal instability, anaphase catastrophe

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Marcel Kemper, Georg Evers, Arik Bernard Schulze, Jan Sperveslage, Christoph Schülke, Georg Lenz, Thomas Herold, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Annalen Bleckmann

Published Aug 23, 2021 · Vol. 12, No. 19 · pp. 1946-1952

Keywords: NSCLC, resistance mutations, ALK, KRAS, ALK inhibitors

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Ricardo Paz-Fumagalli, Jacob Core, Carlos Padula, Seyed Montazeri, John McKinney, Gregory Frey, Zlatko Devcic, Andrew Lewis, Charles Ritchie, Kabir Mody, Sunil Krishnan, Beau Toskich

Published Aug 21, 2021 · Vol. 12, No. 20 · pp. 2075-2088

Keywords: Yttrium-90, radioembolization, cholangiocarcinoma, angiography, radiation dosimetry

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Zachary R. Wakefield, Mai Tanaka, Christine Pampo, Sharon Lepler, Lori Rice, Joy Guingab-Cagmat, Timothy J. Garrett, Dietmar W. Siemann

Published Aug 18, 2021 · Vol. 12, No. 18 · pp. 1737-1748

Keywords: aerobic exercise, breast cancer, hypoxia, doxorubicin, cardiotoxicity

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

Ingrid Dubois-Vedrenne, Diana Al Delbany, Olivier De Henau, Virginie Robert, Maxime Vernimmen, Francina Langa, Anne Lefort, Frédérick Libert, Valérie Wittamer, Marc Parmentier

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1903-1919

Keywords: chemerin, ChemR23, CMKLR1, Rarres2, tumor angiogenesis

Nanoparticle T cell engagers for the treatment of acute myeloid leukemia Research Paper

Kinan Alhallak, Jennifer Sun, Barbara Muz, Amanda Jeske, Jessica Yavner, Hannah Bash, Chaelee Park, Berit Lubben, Ola Adebayo, Samuel Achilefu, John F. DiPersio, Abdel Kareem Azab

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1878-1885

Keywords: acute myeloid leukemia, T cell engagers, nanoparticles, 3D tissue culture model

Correction: IL-17A weakens the antitumor immunity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice Correction

Juan Wang, Yue Zhang, Kai Yin, Peiqi Xu, Jie Tian, Jie Ma, Xinyu Tian, Yungang Wang, Xinyi Tang, Huaxi Xu, Shengjun Wang

Published Aug 14, 2021 · Vol. 13, No. 1 · pp. 425-425

Effect of hypertension and medication use regularity on postoperative delirium after maxillofacial tumors radical surgery Research Paper

Shuyi Kong, Jing Wang, Hui Xu, Kaiqiang Wang

Published Aug 11, 2021 · Vol. 12, No. 18 · pp. 1811-1820

Keywords: the elderly, oral tumor surgery, hypertension, postoperative delirium

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Hélène Marijon, Sigal Gery, Hua Chang, Yosef Landesman, Sharon Shacham, Dhong Hyun Lee, Aimery de Gramont, Harold Phillip Koeffler

Published Aug 10, 2021 · Vol. 12, No. 18 · pp. 1749-1762

Keywords: selinexor, XPO1, olaparib, triple negative breast cancer, BRCA1

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Case Report

Kevin Drenner, Gargi D. Basu, Laurie J. Goodman, Audrey A. Ozols, Janine R. LoBello, Thomas Royce, Michael S. Gordon, Erkut H. Borazanci, Margaux A. Steinbach, Jeffrey Trent, Sunil Sharma

Published Aug 6, 2021 · Vol. 12, No. 18 · pp. 1836-1847

Keywords: whole exome sequencing, RNA sequencing, precision medicine, rare mutations, genomic alteration

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Marina Simón, Jesper Tranekjær Jørgensen, Karina Juhl, Andreas Kjaer

Published Aug 3, 2021

Keywords: photothermal therapy (PTT), indocyanine green (ICG), urokinase plasminogen activator receptor (uPAR), cancer, hyperthermia

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A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Correction: MicroRNA-126 inhibits tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression Correction

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

Nanoparticle T cell engagers for the treatment of acute myeloid leukemia Research Paper

Correction: IL-17A weakens the antitumor immunity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice Correction

Effect of hypertension and medication use regularity on postoperative delirium after maxillofacial tumors radical surgery Research Paper

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Case Report

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

The experiences and needs of Australian medical oncologists in integrating comprehensive genomic profiling into clinical care: a nation-wide survey Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Correction: MicroRNA-126 inhibits tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression Correction

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Safety and initial efficacy of ablative radioembolization for the treatment of unresectable intrahepatic cholangiocarcinoma Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

Nanoparticle T cell engagers for the treatment of acute myeloid leukemia Research Paper

Correction: IL-17A weakens the antitumor immunity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice Correction

Effect of hypertension and medication use regularity on postoperative delirium after maxillofacial tumors radical surgery Research Paper

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Case Report

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper