The Oncosearch | Oncotarget

A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma. Research Paper

Francesco Sottile, Ilaria Gnemmi, Sandra Cantilena, Walter C. D'Acunto, Arturo Sala

Published May 19, 2012 · Vol. 3, No. 5 · pp. 535-545

Keywords: Neuroblastoma, chemotherapeutic drug, oncogene, transcription

On the presence and role of human gene-body DNA methylation Research Paper

Daudi Jjingo, Andrew B. Conley, Soojin V. Yi, Victoria V. Lunyak, I. King Jordan

Published May 9, 2012 · Vol. 3, No. 4 · pp. 462-474

Keywords: genome-wide methylation, epigenetic mark, intragenic transcription, methylating enzyme complexes

BRCA1/p220 loss triggers BRCA1-IRIS overexpression via mRNA stabilization in breast cancer cells Research Paper

Yoshiko Shimizu, Nicole Mullins, Zannel Blanchard, Wael M. ElShamy

Published Mar 19, 2012 · Vol. 3, No. 3 · pp. 299-313

Keywords: BRCA1/p220, BRCA1-IRIS, breast cancer, RNA stability, survival, invasion/metastasis.

Regulation of p53: a collaboration between Mdm2 and Mdmx Review

Dongsheng Pei, Yanping Zhang, Junnian Zheng

Published Mar 10, 2012 · Vol. 3, No. 3 · pp. 228-235

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1 Research Paper

Julie S. Barber-Rotenberg, Saravana P. Selvanathan, Yali Kong, Hayriye V. Erkizan, Tara M. Snyder, S. Peter Hong, Christina L. Kobs, Natalie L. South, Steven Summer, Philip J. Monroe, Maksymilian Chruszcz, Veselin Dobrev, Perrer N. Tosso, Lauren J. Scher, Wladek Minor, Milton L. Brown, Steven J. Metallo, Aykut Ãœren, Jeffrey A. Toretsky

Published Feb 29, 2012 · Vol. 3, No. 2 · pp. 172-182

Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma Research Paper

Hideo Hidaka, Naohiko Seki, Hirofumi Yoshino, Takeshi Yamasaki, Yasutoshi Yamada, Nijiro Nohata, Miki Fuse, Masayuki Nakagawa, Hideki Enokida

Published Jan 30, 2012 · Vol. 3, No. 1 · pp. 44-57

Keywords: microRNA, expression signature, miR-1285, tumor suppressor, renal cell carcinoma, transglutaminase 2

Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor Review

Esha Madan, Rajan Gogna, Madan Bhatt, Uttam Pati, Periannan Kuppusamy, Abbas Ali Mahdi

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 948-957

Keywords: p53, TIGAR, SCO2, metabolism, senescence, aging

Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1 Research Paper

Yan Hu, Mary L. Spengler, Karen K. Kuropatwinski, Maria Comas, Marilyn Jackson, Mikhail V. Chernov, Anatoly S. Gleiberman, Natalia Fedtsova, Youcef M. Rustum, Andrei V. Gudkov, Marina Antoch

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 1279-1290

Keywords: L-Methyl-selenocysteine, TIEG1, circadian rhythms, cyclophosphamide, anticancer treatment, liver, transcription

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

Paul M. Neilsen, Jacqueline E. Noll, Rachel J. Suetani, Renee B Schulz, Fares Al-Ejeh, Andreas Evdokiou, David P. Lane, David F. Callen

Published Dec 25, 2011 · Vol. 2, No. 12 · pp. 1203-1217

Keywords: mutant p53, p63, secretome, invasion

The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA Research Paper

Ming Wang, Andrei L. Gartel

Published Dec 25, 2011 · Vol. 2, No. 12 · pp. 1218-1226

Keywords: FOXM1, siRNA, breast cancer, Aurora B kinase

Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1 Research Paper

Kiran Kumar Velpula, Venkata Ramesh Dasari, Andrew J. Tsung, Dzung H. Dinh, Jasti S. Rao

Published Dec 18, 2011 · Vol. 2, No. 12 · pp. 1028-1042

Keywords: Twist1, Sox2, human umbilical cord blood derived mesenchymal stem cells (hUCBSC), glioma stem cells (GSC), human Glioblastoma (hGBM), epithelial to mesenchymal transition (EMT), mesenchymal to epithelial transition (MET).

Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms Research Paper

Cheryl M. Koh, Tsuyoshi Iwata, Qizhi Zheng, Carlise Bethel, Srinivasan Yegnasubramanian, Angelo M. De Marzo

Published Sep 19, 2011 · Vol. 2, No. 9 · pp. 669-683

Keywords: Myc, EZH2, prostate cancer

Evi1 forms a bridge between the epigenetic machinery and signaling pathways Research Perspective

Akihide Yoshimi, Mineo Kurokawa

Published Jul 26, 2011 · Vol. 2, No. 7 · pp. 575-586

Keywords: Evi1, Leukemia, Polycomb, PTEN, Rapamycin

Molecular signature induced by RNASET2, a tumor antagonizing gene, in ovarian cancer cells Research Perspective

Francesco Acquati, Laura Monti, Marta Lualdi, Marco Fabbri, Maria Grazia Sacco, Laura Gribaldo, Roberto Taramelli

Published Jun 4, 2011 · Vol. 2, No. 6 · pp. 477-484

Keywords: RNases, cancer microenvironment, transcriptional profile.

A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunity Research Perspective

Benjamin Ory, Leif W. Ellisen

Published Mar 23, 2011 · Vol. 2, No. 3 · pp. 259-264

Keywords: p63, p73, microRNA, apoptosis, cisplatin, squamous cell carcinoma, triple-negative breast cancer, chemosensitivity

Natural Antisense Transcript: A Concomitant Engagement with Protein-Coding Transcript Research Perspective

Keguo Li, Ramani Ramchandran

Published Oct 9, 2010 · Vol. 1, No. 6 · pp. 447-452

PAFc, a Key Player in MLL-rearranged Leukemogenesis Research Perspective

Jiaying Tan, Andrew G. Muntean, Jay L. Hess

Published Oct 5, 2010 · Vol. 1, No. 6 · pp. 461-465

The Siah2-HIF-FoxA2 axis in prostate cancer â€“ new markers and therapeutic opportunities Research Perspective

Jianfei Qi, Maurizio Pellecchia, Zeâ€™ev A. Ronai

Published Sep 24, 2010 · Vol. 1, No. 5 · pp. 379-385

p300- and Myc-mediated regulation of glioblastoma multiforme cell differentiation Research Paper

Sreejith P. Panicker, Baisakhi Raychaudhuri, Pankaj Sharma, Russell Tipps, Tapati Mazumdar, Asoke K. Mal, Juan M. Palomo, Michael A. Vogelbaum, S. Jaharul Haque

Published Aug 4, 2010 · Vol. 1, No. 4 · pp. 289-303

ID4: a new player in the cancer arena Research Perspective

Stefania Dellâ€™Orso, Federica Ganci, Sabrina Strano, Giovanni Blandino, Giulia Fontemaggi

Published May 1, 2010 · Vol. 1, No. 1 · pp. 48-58

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A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma. Research Paper

On the presence and role of human gene-body DNA methylation Research Paper

BRCA1/p220 loss triggers BRCA1-IRIS overexpression via mRNA stabilization in breast cancer cells Research Paper

Regulation of p53: a collaboration between Mdm2 and Mdmx Review

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1 Research Paper

Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma Research Paper

Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor Review

Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1 Research Paper

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA Research Paper

Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1 Research Paper

Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms Research Paper

Evi1 forms a bridge between the epigenetic machinery and signaling pathways Research Perspective

Molecular signature induced by RNASET2, a tumor antagonizing gene, in ovarian cancer cells Research Perspective

A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunity Research Perspective

Natural Antisense Transcript: A Concomitant Engagement with Protein-Coding Transcript Research Perspective

PAFc, a Key Player in MLL-rearranged Leukemogenesis Research Perspective

The Siah2-HIF-FoxA2 axis in prostate cancer â€“ new markers and therapeutic opportunities Research Perspective

p300- and Myc-mediated regulation of glioblastoma multiforme cell differentiation Research Paper

ID4: a new player in the cancer arena Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma. Research Paper

On the presence and role of human gene-body DNA methylation Research Paper

BRCA1/p220 loss triggers BRCA1-IRIS overexpression via mRNA stabilization in breast cancer cells Research Paper

Regulation of p53: a collaboration between Mdm2 and Mdmx Review

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1 Research Paper

Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma Research Paper

Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor Review

Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1 Research Paper

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome Research Paper

The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA Research Paper

Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1 Research Paper

Myc Enforces Overexpression of EZH2 in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms Research Paper

Evi1 forms a bridge between the epigenetic machinery and signaling pathways Research Perspective

Molecular signature induced by RNASET2, a tumor antagonizing gene, in ovarian cancer cells Research Perspective

A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunity Research Perspective

Natural Antisense Transcript: A Concomitant Engagement with Protein-Coding Transcript Research Perspective

PAFc, a Key Player in MLL-rearranged Leukemogenesis Research Perspective

The Siah2-HIF-FoxA2 axis in prostate cancer â€“ new markers and therapeutic opportunities Research Perspective

p300- and Myc-mediated regulation of glioblastoma multiforme cell differentiation Research Paper

ID4: a new player in the cancer arena Research Perspective