The Oncosearch | Oncotarget

Prognostic role of microRNAs in breast cancer: A systematic review Review

Eleni Zografos, Flora Zagouri, Despoina Kalapanida, Roubini Zakopoulou, Anastasios Kyriazoglou, Kleoniki Apostolidou, Maria Gazouli, Meletios-Athanasios Dimopoulos

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7156-7178

Keywords: breast cancer, microRNAs, prognosis, biomarkers

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Ewa M. Kosciuczuk, Aroop K. Kar, Gavin T. Blyth, Mariafausta Fischietti, Sameem Abedin, Alain A. Mina, Rebekah Siliezar, Tomasz Rzymski, Krzysztof Brzozka, Elizabeth A. Eklund, Elspeth M. Beauchamp, Frank Eckerdt, Diana Saleiro, Leonidas C. Platanias

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7112-7121

Keywords: acute myeloid leukemia, MNK, eIF4E, kinase inhibitor, SEL201

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

Lidia Franco-Luzón, África González-Murillo, Cristina Alcántara-Sánchez, Lorena García-García, Maryam Tabasi, Ana Luis Huertas, Louis Chesler, Manuel Ramírez

Published Dec 12, 2019

Keywords: oncolytic virotherapy, neuroblastoma, mesenchymal stem cells, tumor microenvironment, immune response

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Chunmei Zhao, Benjamin J. Thompson, Kelly Chen, Feng Gao, Barbara Blouw, Mathieu Marella, Susan Zimmerman, Trevor Kimbler, Sheryl Garrovillo, Jesse Bahn, Lei Huang, Zhongdong Huang, H. Michael Shepard, Sanna Rosengren, Christopher D. Thanos, Daniel C. Maneval

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6561-6576

Keywords: hyaluronan, breast cancer, xenograft, tumor microenvironment, CD44

The multifaceted anti-cancer effects of BRAF-inhibitors Review

Laura Croce, Francesca Coperchini, Flavia Magri, Luca Chiovato, Mario Rotondi

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6623-6640

Keywords: BRAF, BRAF-inhibitors, tumor microenvironment, chemokines, CXCL8

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

David King, Xiao Dun Li, Gilberto S. Almeida, Colin Kwok, Polly Gravells, Daniel Harrison, Saoirse Burke, Albert Hallsworth, Yann Jamin, Sally George, Simon P. Robinson, Christopher J. Lord, Evon Poon, Daniel Yeomanson, Louis Chesler, Helen E. Bryant

Published Nov 6, 2019 · Vol. 11, No. 23 · pp. 2141-2159

Keywords: PARP inhibitor, neuroblastoma, MYCN, replication stress, replication fork stalling

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study Research Paper

Sarina A. Piha-Paul, Matthew H. Taylor, Daniel Spitz, Lee Schwartzberg, J. Thaddeus Beck, Todd M. Bauer, Funda Meric-Bernstam, Das Purkayastha, Linda Karpiak, Sebastian Szpakowski, Fadi Braiteh

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6526-6535

Keywords: phosphatidylinositol 3-kinase pathway, buparlisib, advanced malignancies, molecular selection, tissue agnostic

The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes Research Paper

Francesca Coperchini, Laura Croce, Marco Denegri, Oriana Awwad, Samuel Tata Ngnitejeu, Flavia Magri, Luca Chiovato, Mario Rotondi

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6432-6443

Keywords: phenformin, tumor-microenvironment, thyroid cancer, CXCL8

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

C. Andrew Boswell, Daniela Bumbaca Yadav, Eduardo E. Mundo, Shang-Fan Yu, Jennifer Arca Lacap, Aimee Fourie-O’Donohue, Katherine R. Kozak, Gregory Z. Ferl, Crystal Zhang, Jason Ho, Sheila Ulufatu, Leslie A. Khawli, Kedan Lin

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6234-6244

Keywords: antibody-drug conjugate, prostate cancer, pharmacokinetics, TENB2, imaging

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

Inayatullah Shaikh, Afzal Ansari, Garima Ayachit, Monika Gandhi, Priyanka Sharma, Shivarudrappa Bhairappanavar, Chaitanya G. Joshi, Jayashankar Das

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6168-6183

Keywords: tobacco, head and neck squamous cell carcinoma (HNSCC), differentially expressed genes, hub gene, miRNA

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Abbas Hadji, Greta K. Schmitt, Mathew R. Schnorenberg, Lauren Roach, Connie M. Hickey, Logan B. Leak, Matthew V. Tirrell, James L. LaBelle

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6219-6233

Keywords: MCL-1, BIM, BH3 mimetic, stapled peptides, apoptosis

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Amanda M. Smith, Christine R.C. Zhang, Alexandre S. Cristino, John P. Grady, J. Lynn Fink, Andrew S. Moore

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5755-5767

Keywords: myeloid leukemia, therapy, drug resistance, hematological malignancies, gene mutation

Engineered human platelet-derived microparticles as natural vectors for targeted drug delivery Research Paper

Jyotsna Kailashiya, Vineeta Gupta, Debabrata Dash

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5835-5846

Keywords: cancer targeting, drug-delivery vector, doxorubicin, leukemia, platelet-derived microparticles

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

Elisabeth Baron, Shubai Liu, Yuanyuan Hua, Junzheng Yang, Pui-Wah Choi, Wing-Chung Ng, Shu-Kay Ng, Jinyan Du, Charlene C. Ng, Xiao Zhen Zhou, Kun Ping Lu, William R. Welch, Christopher P. Crum, Ross S. Berkowitz, Shu-Wing Ng

Published Sep 3, 2019 · pp. 5724-5736

Keywords: cell cycle regulation, drug sensitivity, ovarian cancer, signal transduction, combination treatment

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Nicci Owusu-Brackett, Kurt W. Evans, Argun Akcakanat, Erkan Yuca, Coya Tapia, Yasmeen Qamar Rizvi, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5011-5019

Keywords: breast cancer, TAK228, PI3K, PTEN, TNBC

Olfactory ensheathing cells travel their natural nasal pathway to deliver therapeutics to brain tumors Editorial

Litia A. Carvalho, Bakhos A. Tannous

Published Jun 19, 2019 · Vol. 10, No. 43 · pp. 4351-4353

Keywords: olfactory ensheathing cells, glioma, gene therapy

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Ann M. Moyer, Jia Yu, Jason P. Sinnwell, Travis J. Dockter, Vera J. Suman, Richard M. Weinshilboum, Judy C. Boughey, Matthew P. Goetz, Daniel W. Visscher, Liewei Wang

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3924-3930

Keywords: patient-derived xenografts, breast cancer, Ki67, NOD-SCID mice, NSG mice

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Peter Y.M. Woo, Tai-Chung Lam, Jenny K.S. Pu, Lai-Fung Li, Roland C.Y. Leung, Jason M.K. Ho, James T.F. Zhung, Belinda Wong, Timonthy S.K. Chan, Herbert H.F. Loong, Ho-Keung Ng

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3818-3826

Keywords: glioblastoma, BRAF^V600E mutation, targeted therapies, BRAF-MEK inhibitors

Meta-analytical methods for estimating outcomes from overall response rate in patients with relapsed/refractory diffuse large B-cell lymphoma Meta-Analysis

Ling Wang, Hung Lam, Yaping Shou, Aaron Galaznik

Published May 14, 2019 · Vol. 10, No. 35 · pp. 3285-3293

Keywords: diffuse large B-cell lymphoma, meta-analyses, outcomes, overall response rate, durable response rate

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Hemayet Ullah, Wangheng Hou, Sivanesan Dakshanamurthy, Qiyi Tang

Published May 14, 2019 · Vol. 10, No. 35 · pp. 3209-3226

Keywords: host targeted antiviral (HTA), herpes simplex virus (HSV), receptor for activated C kinase 1 (RACK1), RACK1 inhibitor, internal ribosomal entry site (IRES)

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Prognostic role of microRNAs in breast cancer: A systematic review Review

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

The multifaceted anti-cancer effects of BRAF-inhibitors Review

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study Research Paper

The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes Research Paper

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Engineered human platelet-derived microparticles as natural vectors for targeted drug delivery Research Paper

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Olfactory ensheathing cells travel their natural nasal pathway to deliver therapeutics to brain tumors Editorial

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Meta-analytical methods for estimating outcomes from overall response rate in patients with relapsed/refractory diffuse large B-cell lymphoma Meta-Analysis

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Prognostic role of microRNAs in breast cancer: A systematic review Review

Inhibitory effects of SEL201 in acute myeloid leukemia Research Paper

Systemic oncolytic adenovirus delivered in mesenchymal carrier cells modulate tumor infiltrating immune cells and tumor microenvironment in mice with neuroblastoma Research Paper

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

The multifaceted anti-cancer effects of BRAF-inhibitors Review

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study Research Paper

The anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes Research Paper

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer Research Paper

Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures Research Paper

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Engineered human platelet-derived microparticles as natural vectors for targeted drug delivery Research Paper

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Olfactory ensheathing cells travel their natural nasal pathway to deliver therapeutics to brain tumors Editorial

Spontaneous murine tumors in the development of patient-derived xenografts: a potential pitfall Research Paper

Regression of BRAFV600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Meta-analytical methods for estimating outcomes from overall response rate in patients with relapsed/refractory diffuse large B-cell lymphoma Meta-Analysis

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report