The Oncosearch | Oncotarget

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice Retraction

Fariba Poosti, Ruchi Bansal, Saleh Yazdani, Jai Prakash, Leonie Beljaars, Jacob van den Born, Martin H. de Borst, Harry van Goor, Jan-Luuk Hillebrands, Klaas Poelstra

Published Oct 25, 2023 · Vol. 15, No. 1 · pp. 35-35

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells Research Paper

Takahiro Yamakawa, Guoxiang Zhang, Liza Bengrine Najjar, Chun Li, Keiichi Itakura

Published Jul 8, 2023 · Vol. 14, No. 1 · pp. 723-737

Keywords: KIAA0930, cancer cachexia, muscle atrophy, inflammatory cytokines/chemokines, protein secretion

Targeting Ras with protein engineering Review

Atilio Tomazini, Julia M. Shifman

Published Jun 21, 2023 · Vol. 14, No. 1 · pp. 672-687

Keywords: Ras oncogene, anti-Ras therapeutics, Ras targeting, protein engineering, protein design

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

Hongyan Yuan, Lu Jin, Handan Xiang, Anannya Bhattacharya, Philip E. Brandish, Gretchen Baltus, Alexander Tong, Changyan Zhou, Robert I. Glazer

Published Dec 10, 2022 · Vol. 13, No. 1 · pp. 1350-1358

Keywords: PD-1, NeuT, Wnt, macrophages, mammary tumorigenesis

An ABC transporter as a potential target against SHH-Medulloblastoma: From Benchtop to Bedside Editorial

Jingwen Zhu, Joseph N. Miller, John D. Schuetz

Published Sep 2, 2022 · Vol. 13, No. 1 · pp. 1017-1019

Keywords: transporter, chemotherapeutics

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma Research Paper

Francis R. LeBlanc, Zainul S. Hasanali, August Stuart, Sara Shimko, Kamal Sharma, Violetta V. Leshchenko, Samir Parekh, Haiqing Fu, Ya Zhang, Melvenia M. Martin, Mark Kester, Todd Fox, Jiangang Liao, Thomas P. Loughran, Juanita Evans, Jeffrey J. Pu, Stephen E. Spurgeon, Mirit I. Aladjem, Elliot M. Epner

Published Jul 9, 2022 · Vol. 13, No. 1 · pp. 986-1002

Keywords: epigenetics, blastic mantle cell lymphoma, cladribine

CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling Research Paper

Limeng Pu, Manali Singha, Jagannathan Ramanujam, Michal Brylinski

Published May 9, 2022 · Vol. 13, No. 1 · pp. 695-706

Keywords: cancer growth rate, kinase inhibitors, differential gene expression, gene-disease association, cancer-specific networks

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Monica Sharma, Isabel Castro-Piedras, Fahmida Rasha, Sabarish Ramachandran, Souad R. Sennoune, Kathryn Furr, Sharilyn Almodovar, Vadivel Ganapathy, Matthew B. Grisham, Rakhshanda Layeequr Rahman, Kevin Pruitt

Published Sep 28, 2021 · Vol. 12, No. 22 · pp. 2234-2251

Keywords: dishevelled (DVL), post-translational modification, lysine residue, gene expression, chromatin immunoprecipitation (ChIP)

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Ilyas Sahin, Andrew George, Shengliang Zhang, Kelsey E. Huntington, Zehra Ordulu, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 24, 2021 · Vol. 12, No. 21 · pp. 2131-2146

Keywords: cancer immunotherapy, immune checkpoint inhibitors, hyperprogressive disease (HPD), hyperprogression (HP), humanized mouse

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Sofia Leaf, Lindsey Carlsen, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1992-2005

Keywords: breast cancer, colorectal cancer, BRCA1, biomarker, early onset

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

Shuai Zhao, Wafik S. El-Deiry

Published Sep 15, 2021 · Vol. 12, No. 20 · pp. 1970-1979

Keywords: Smurf2, CDK4/6 inhibition, HIF1alpha, hypoxia, cancer therapy

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Kelsey E. Huntington, Anna Louie, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 11, 2021 · Vol. 12, No. 20 · pp. 1980-1991

Keywords: cytokine profiling, inflammatory response, chemokine, growth factor, immune profiling

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Lindsey Carlsen, Christoph Schorl, Kelsey Huntington, Liz Hernandez-Borrero, Aakash Jhaveri, Shengliang Zhang, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 8, 2021 · Vol. 12, No. 20 · pp. 2006-2021

Keywords: chemotherapy mechanism, colon cancer, 5-fluorouracil, irinotecan, oxaliplatin

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Angeliki Andrikopoulou, Evangelos Terpos, Spyridoula Chatzinikolaou, Kleoniki Apostolidou, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Meletios-Athanasios Dimopoulos, Flora Zagouri

Published Sep 2, 2021 · Vol. 12, No. 21 · pp. 2206-2214

Keywords: TP53 mutations, next-generation sequencing, biomarker, prognosis, breast cancer

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

Ingrid Dubois-Vedrenne, Diana Al Delbany, Olivier De Henau, Virginie Robert, Maxime Vernimmen, Francina Langa, Anne Lefort, Frédérick Libert, Valérie Wittamer, Marc Parmentier

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1903-1919

Keywords: chemerin, ChemR23, CMKLR1, Rarres2, tumor angiogenesis

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Hélène Marijon, Sigal Gery, Hua Chang, Yosef Landesman, Sharon Shacham, Dhong Hyun Lee, Aimery de Gramont, Harold Phillip Koeffler

Published Aug 10, 2021 · Vol. 12, No. 18 · pp. 1749-1762

Keywords: selinexor, XPO1, olaparib, triple negative breast cancer, BRCA1

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Nikolai Petrov, Hee-Sheung Lee, Mikhail Liskovykh, Marie-Paule Teulade-Fichou, Hiroshi Masumoto, William C. Earnshaw, Yves Pommier, Vladimir Larionov, Natalay Kouprina

Published Jun 27, 2021 · Vol. 12, No. 15 · pp. 1444-1456

Keywords: chromosome instability, CIN, platinum-derived G4-quadruplexes, telomere dysfunction, human artificial chromosome

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Reza Bayat Mokhtari, Bessi Qorri, Narges Baluch, Angelo Sparaneo, Federico Pio Fabrizio, Lucia Anna Muscarella, Albina Tyker, Sushil Kumar, Hai-Ling Margaret Cheng, Myron R. Szewczuk, Bikul Das, Herman Yeger

Published Jun 22, 2021 · Vol. 12, No. 15 · pp. 1470-1489

Keywords: sulforaphane, acetazolamide, bronchial carcinoid tumors, serotonin, carbonic anhydrase

Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells Research Paper

Andrew E. Greenstein, Hazel J. Hunt

Published Jun 9, 2021 · Vol. 12, No. 13 · pp. 1243-1255

Keywords: glucocorticoid, tumors, apoptosis, chemotherapy, drug resistance

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Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice Retraction

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells Research Paper

Targeting Ras with protein engineering Review

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

An ABC transporter as a potential target against SHH-Medulloblastoma: From Benchtop to Bedside Editorial

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma Research Paper

CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Retraction: Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice Retraction

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells Research Paper

Targeting Ras with protein engineering Review

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

An ABC transporter as a potential target against SHH-Medulloblastoma: From Benchtop to Bedside Editorial

Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma Research Paper

CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients Research Paper

Identification of Smurf2 as a HIF-1α degrading E3 ubiquitin ligase Priority Research Paper

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper