The Oncosearch | Oncotarget

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Josephine Dubois, Jacqueline Rueger, Bernhard Haubold, Rosel Kretschmer-Kazemi Far, Georg Sczakiel

Published Apr 24, 2021 · Vol. 12, No. 10 · pp. 1011-1023

Keywords: tumor diagnostics, non-invasive, urine RNA, biomarker, transcriptome analysis

Association between miRNA signatures in serum samples from epidermal growth factor inhibitor treated patients and skin toxicity Research Paper

Sarah Kemski, Vivien Molitor, Michael Steffens, Tim J. Nümm, Nadine Herrmann, Thorsten Hornung, Thomas Bieber, Christian Schumann, Volker Kächele, Thomas Seufferlein, Volker Heinemann, Catharina Scholl, Julia Carolin Stingl

Published Apr 24, 2021 · Vol. 12, No. 10 · pp. 982-995

Keywords: miRNA, EGFR, EGFRI, cancer, skin toxicity

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Aditya Kulkarni, Joseph Ryan McDermott, Umesh Kathad, Rama Modali, Jean-Philippe Richard, Panna Sharma, Kishor Bhatia

Published Apr 5, 2021 · Vol. 12, No. 8 · pp. 791-806

Keywords: non-small cell lung cancer, acylfulvene, alkylating agent, PTGR1, LP-184

Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens Research Paper

Kamala Vanarsa, Shereen Enan, Pooja Patel, Briony Strachan, Anto Sam Crosslee Louis Sam Titus, Aphrihl Dennis, Yair Lotan, Chandra Mohan

Published Mar 31, 2021 · Vol. 12, No. 8 · pp. 783-790

Keywords: urothelial, proteomics, targeted screens, interleukins, inflammation

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Sateja Paradkar, James Herrington, Adam Hendricson, Piyasena Hewawasam, Mark Plummer, Denton Hoyer, Ranjini K. Sundaram, Yulia V. Surovtseva, Ranjit S. Bindra

Published Mar 27, 2021 · Vol. 12, No. 9 · pp. 891-906

Keywords: glioblastoma, radiosensitizers, mibefradil, DNA repair, alternative non-homologous end joining

Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors Research Paper

Karamat Mohammad, Vladimir I. Titorenko

Published Mar 19, 2021 · Vol. 12, No. 7 · pp. 608-625

Keywords: cellular aging, geroprotectors, caloric restriction, metabolism, methionine

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Christelle Morris, Sébastien Durand, Pierre Jalinot

Published Mar 13, 2021 · Vol. 12, No. 7 · pp. 649-664

Keywords: breast cancer, senescence-associated secretory phenotype, eIF3, PARP1, mTORC1

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Duna H. Barakeh, Rasha Aljelaify, Yara Bashawri, Amal Almutairi, Fatimah Alqubaishi, Mohammed Alnamnakani, Latifa Almubarak, Abdulrahman Al Naeem, Fatema Almushawah, May Alrashed, Malak Abedalthagafi

Published Feb 27, 2021 · Vol. 12, No. 7 · pp. 686-697

Keywords: breast cancer, PIK3CA, BCa, Saudi Arabia, BRCA

Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Paper

Asim Joshi, Rohit Mishra, Sanket Desai, Pratik Chandrani, Hitesh Kore, Roma Sunder, Supriya Hait, Prajish Iyer, Vaishakhi Trivedi, Anuradha Choughule, Vanita Noronha, Amit Joshi, Vijay Patil, Nandini Menon, Rajiv Kumar, Kumar Prabhash, Amit Dutt

Published Feb 19, 2021 · Vol. 12, No. 6 · pp. 578-588

Keywords: lung squamous carcinoma, genetic alterations, druggable mutations, whole exome sequencing, mass spectrometry

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

Ryan R. Kawalerski, Steven D. Leach, Luisa F. Escobar-Hoyos

Published Feb 12, 2021 · Vol. 12, No. 6 · pp. 525-533

Keywords: pancreatic cancer, RNA splicing, targeted therapy, KRAS, TP53

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Rolando Pérez-Lorenzo, Stephanie O. Erjavec, Angela M. Christiano, Raphael Clynes

Published Jan 6, 2021 · Vol. 12, No. 2 · pp. 66-80

Keywords: anti-tumor antibodies, targeted therapy, immunotherapy, combination therapies, melanoma

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Jordan L. Kohlmeyer, David J. Gordon, Munir R. Tanas, Rebecca D. Dodd, Varun Monga, Benjamin W. Darbro, Dawn E. Quelle

Published Dec 26, 2020 · Vol. 12, No. 1 · pp. 10-14

Keywords: MPNST, RABL6A-RB1 signaling, CDK4/6 and MEK inhibitors, Ras, targeted cancer therapy

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper

Ahmed Elhassanny, Rene Escobedo, Daniel Ladin, Colin Burns, Rukiyah Van Dross

Published Dec 22, 2020 · Vol. 11, No. 52 · pp. 4788-4802

Keywords: calreticulin, endoplasmic reticulum stress, dendritic cells, endocannabinoid metabolite

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Yvonne Cornejo, Min Li, Thanh H. Dellinger, Rachael Mooney, Masmudur M. Rahman, Grant McFadden, Karen S. Aboody, Mohamed Hammad

Published Dec 8, 2020 · Vol. 11, No. 51 · pp. 4693-4698

Keywords: oncolytic virotherapy, myxoma, NSCs, ovarian cancer

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Katarina Reis, Jack L. Arbiser, Anders Hjerpe, Katalin Dobra, Pontus Aspenström

Published Dec 4, 2020 · Vol. 11, No. 50 · pp. 4637-4647

Keywords: malignant mesothelioma, actin dynamics, vimentin, cytoskeleton, imipramine blue

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Ahmad A. Nazem, Jacob Ruzevick, Manuel J. Ferreira Jr

Published Dec 2, 2020 · Vol. 11, No. 49 · pp. 4544-4553

Keywords: meningioma, skull base, NGS, sequencing, biomarker

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Pascale Tomasini, Fabrice Barlesi, Sophie Gilles, Isabelle Nanni-Metellus, Riccardo Soffietti, Emilie Denicolai, Eric Pellegrino, Emilie Bialecki, L’Houcine Ouafik, Philippe Metellus

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4648-4654

Keywords: lung cancer, brain metastasis, whole exome sequencing, comparison, mutations

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

Paloma Bragado, Patricia Fernández-Nogueira, Neus Carbó, Pere Gascón

Published Nov 23, 2020 · Vol. 11, No. 49 · pp. 4541-4543

Keywords: breast cancer, TAFs, FGFR2, FGF5, trastuzumab

A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer Case Report

Sewanti Limaye, Prashant Kumar, Ramya Pragya, Janani Sambath, Darshana Patil, Ajay Srinivasan, Sachin Apurva, Navin Srivastava, Sanket Patil, Revati Patil, Vineet Datta, Dadasaheb Akolkar, Rajan Datar

Published Nov 5, 2020 · Vol. 11, No. 46 · pp. 4358-4363

Keywords: high grade serous ovarian cancer, androgen receptors, bicalutamide

Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy Case Report

Rajnish Nagarkar, Darshana Patil, Sewanti Limaye, Pradip Devhare, Ashwini Ghaisas, Navin Srivastava, Sachin Apurwa, Sanket Patil, Jinumary John, Zarrine Raazi, Aditya Shreenivas, Janani Sambath, Ajay Srinivasan, Prashant Kumar, Dadasaheb Akolkar, Rajan Datar

Published Oct 24, 2020 · Vol. 11, No. 45 · pp. 4195-4200

Keywords: periampullary adenocarcinoma, ETA, HER2, trastuzumab

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Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Association between miRNA signatures in serum samples from epidermal growth factor inhibitor treated patients and skin toxicity Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Paper

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer Case Report

Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy Case Report

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Association between miRNA signatures in serum samples from epidermal growth factor inhibitor treated patients and skin toxicity Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations Research Paper

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma Research Paper

Combination therapies for MPNSTs targeting RABL6A-RB1 signaling Research Perspective

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ12,14 prostamide J2 Research Paper

NSCs are permissive to oncolytic Myxoma virus and provide a delivery method for targeted ovarian cancer therapy Research Paper

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Unraveling the role of fibroblasts, FGF5 and FGFR2 in HER2-targeted therapies resistance and tumor progression Editorial

A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer Case Report

Liquid biopsy and multi-analyte testing guided treatment of HER2 positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy Case Report

Damage-associated molecular pattern (DAMP) activation in melanoma: investigation of the immunogenic activity of 15-deoxy, Δ^12,14 prostamide J₂ Research Paper