The Oncosearch | Oncotarget

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

El-Habib Dakir, Faustino Mollinedo

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5313-5331

Keywords: miRNA, miR-125a-5p, miR-17-92, neutrophil differentiation, human

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Jennifer Bourn, Sony Pandey, Jashim Uddin, Lawrence Marnett, Maria Cekanova

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5168-5180

Keywords: bladder cancer, TKIs, RTKIs, COX-2, targeted therapies

Contemplations on MDMX (MDM4) driving triple negative breast cancer circulating tumor cells and metastasis Research Perspective

Chong Gao, Gu Xiao, Jill Bargonetti

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5007-5010

Keywords: MDMX, MDM4, mutant p53, mtp53, metastasis

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

Huda H. Al-Khalaf, Abdelilah Aboussekhra

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4868-4879

Keywords: osteosarcoma, AUF1, VEGF-A, HIF-1α, angiogenesis

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Sierra A. Colavito, James T. Platt, Matthew A. Held, Zongzhi Liu, Ryan Sokup, David F. Stern

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4822-4839

Keywords: epithelial-mesenchymal transition, triple-negative breast cancer, targeted drug combination screen, claudin-low breast cancer, CHK1

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes Editorial

Cestmir Altaner, Ursula Altanerova, Jana Jakubechova

Published Jul 27, 2019 · Vol. 10, No. 54 · pp. 5573-5575

Keywords: mesenchymal stem/stromal cells, exosome, suicide gene, yCD::UPRT, 5-fluorocytosine, 5-fluorouracil

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Mary K. Nesline, Paul DePietro, Grace K. Dy, Amy Early, Antonios Papanicolau-Sengos, Jeffrey M. Conroy, Felicia L. Lenzo, Sean T. Glenn, Hongbin Chen, Anne Grand’Maison, Patrick Boland, Marc S. Ernstoff, Igor Puzanov, Stephen Edge, Stacey Akers, Mateusz Opyrchal, Gurkamal Chatta, Kunle Odunsi, Peter Frederick, Shashikant Lele, Mark Gardner, Carl Morrison

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4616-4629

Keywords: comprehensive genomic profiling, targeted therapy, clinical decision making, next-generation sequencing, real world data

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Stephen G. Gaffney, Elizabeth B. Perry, Ping-Min Chen, Andrew Greenstein, Susan M. Kaech, Jeffrey P. Townsend

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4532-4545

Keywords: immunotherapy, tumor microenvironment, T lymphocyte, cancer genomics, RNA-seq

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

Feng-Mao Lin, Susan E. Yost, Wei Wen, Paul H. Frankel, Daniel Schmolze, Pei-Guo Chu, Yate-Ching Yuan, Zheng Liu, John Yim, Zhen Chen, Yuan Yuan

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4356-4368

Keywords: AKT, differential expression, AKT targeting, TNBC

The heterogeneity and complexity of Cannabis extracts as antitumor agents Research Paper

Liran Baram, Ella Peled, Paula Berman, Ben Yellin, Elazar Besser, Maya Benami, Igal Louria-Hayon, Gil M. Lewitus, David Meiri

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4091-4106

Keywords: cancer, Cannabis, cannabinoids, (-)-Δ⁹-trans-tetrahydrocannabinol (Δ⁹-THC), antitumor

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population Research Paper

Yuji Urabe, Kenichi Kagemoto, C. Nelson Hayes, Koki Nakamura, Kazuhiko Masuda, Atsushi Ono, Shinji Tanaka, Koji Arihiro, Kazuaki Chayama

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4139-4148

Keywords: early-stage esophageal squamous cell carcinoma, exome sequencing, target sequencing, genomic characterization, TP53

Mutations of the MAPK/TSC/mTOR pathway characterize periventricular glioblastoma with epithelioid SEGA-like morphology–morphological and therapeutic implications Research Paper

Maria-Magdalena Georgescu, Yan Li, Mohammad Zahidul Islam, Christina Notarianni, Hai Sun, Adriana Olar, Gregory N. Fuller

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4038-4052

Keywords: epithelioid glioblastoma, SEGA-like, mTOR, MAPK, 4E-BP1

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Priyal O. Patel, Kathleen I. Pishas, Cenny Taslim, Julia Selich-Anderson, Emily R. Theisen, Stephen L. Lessnick

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3865-3878

Keywords: LSD2/KDM1B, Ewing sarcoma, SP-2509, LSD1/KDM1A

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Richard Glenn C. Delacruz, Imelda T. Sandoval, Kyle Chang, Braden N. Miller, Laura Reyes-Uribe, Ester Borras, Patrick M. Lynch, Melissa W. Taggart, Ernest T. Hawk, Eduardo Vilar, David A. Jones

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3939-3951

Keywords: familial adenomatous polyposis, colon cancer, APC, CNOT3, CtBP1

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Peter Y.M. Woo, Tai-Chung Lam, Jenny K.S. Pu, Lai-Fung Li, Roland C.Y. Leung, Jason M.K. Ho, James T.F. Zhung, Belinda Wong, Timonthy S.K. Chan, Herbert H.F. Loong, Ho-Keung Ng

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3818-3826

Keywords: glioblastoma, BRAF^V600E mutation, targeted therapies, BRAF-MEK inhibitors

Dissecting the role of RNA modification regulatory proteins in melanoma Research Paper

Parmanand Malvi, Biao Wang, Shreni Shah, Romi Gupta

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3745-3759

Keywords: RNA modifications, epitranscriptome, melanoma, MAPK, BRAF mutant melanoma

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

Nadin D. Exner, Jaime Alberto Campos Valenzuela, Khalil Abou-El-Ardat, Hrvoje Miletic, Peter C. Huszthy, Petra M. Radehaus, Evelin Schröck, Rolf Bjerkvig, Lars Kaderali, Barbara Klink, Janice M. Nigro

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3641-3653

Keywords: exome sequencing, IDH1, oligodendroglioma, SNV, xenograft

Adaptive responses in a PARP inhibitor window of opportunity trial illustrate limited functional interlesional heterogeneity and potential combination therapy options Research Paper

Marilyne Labrie, Tae-Beom Kim, Zhenlin Ju, Sanghoon Lee, Wei Zhao, Yong Fang, Yiling Lu, Ken Chen, Pedro Ramirez, Michael Frumovitz, Larissa Meyer, Nicole D. Fleming, Anil K. Sood, Robert L. Coleman, Gordon B. Mills, Shannon N. Westin

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3533-3546

Keywords: poly (ADP-ribose) polymerase inhibitor, combination therapy, adaptive response, ovarian cancer, targeted therapy

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Kathryn Clarke, Christine Young, Fabio Liberante, Mary-Frances McMullin, Alexander Thompson, Ken Mills

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3462-3471

Keywords: HDAC inhibitor, epigenetic, transcriptional regulation, myelodysplastic syndrome (MDS)

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas Research Paper

Joshua Loewenstern, John Rutland, Corey Gill, Hanane Arib, Margaret Pain, Melissa Umphlett, Yayoi Kinoshita, Russell McBride, Michael Donovan, Robert Sebra, Joshua Bederson, Mary Fowkes, Raj Shrivastava

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3506-3517

Keywords: meningioma, tumor recurrence, genomics, driver mutation, progression-free survival

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Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Contemplations on MDMX (MDM4) driving triple negative breast cancer circulating tumor cells and metastasis Research Perspective

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes Editorial

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

The heterogeneity and complexity of Cannabis extracts as antitumor agents Research Paper

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population Research Paper

Mutations of the MAPK/TSC/mTOR pathway characterize periventricular glioblastoma with epithelioid SEGA-like morphology–morphological and therapeutic implications Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Dissecting the role of RNA modification regulatory proteins in melanoma Research Paper

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

Adaptive responses in a PARP inhibitor window of opportunity trial illustrate limited functional interlesional heterogeneity and potential combination therapy options Research Paper

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Contemplations on MDMX (MDM4) driving triple negative breast cancer circulating tumor cells and metastasis Research Perspective

AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes Editorial

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment Research Paper

Differential gene expression and AKT targeting in triple negative breast cancer Research Paper

The heterogeneity and complexity of Cannabis extracts as antitumor agents Research Paper

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population Research Paper

Mutations of the MAPK/TSC/mTOR pathway characterize periventricular glioblastoma with epithelioid SEGA-like morphology–morphological and therapeutic implications Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Research Paper

Regression of BRAFV600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report

Dissecting the role of RNA modification regulatory proteins in melanoma Research Paper

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes Research Paper

Adaptive responses in a PARP inhibitor window of opportunity trial illustrate limited functional interlesional heterogeneity and potential combination therapy options Research Paper

The histone deacetylase inhibitor Romidepsin induces as a cascade of differential gene expression and altered histone H3K9 marks in myeloid leukaemia cells Research Paper

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas Research Paper

Regression of BRAF^V600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases Case Report