The Oncosearch | Oncotarget

MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2 Research Paper

Henan Zhao, Xiaotang Yu, Yanfang Ding, Jinyao Zhao, Guang Wang, Xian Wu, Jiyong Jiang, Chun Peng, Gordon Zhuo Guo, Shiying Cui

Published Jul 20, 2016 · Vol. 7, No. 33 · pp. 53254-53268

PIM kinases as therapeutic targets against advanced melanoma Research Paper

Batool Shannan, Andrea Watters, Quan Chen, Stefan Mollin, Markus DÃ¶rr, Eric Meggers, Xiaowei Xu, Phyllis A. Gimotty, Michela Perego, Ling Li, Joseph Benci, Clemens Krepler, Patricia Brafford, Jie Zhang, Zhi Wei, Gao Zhang, Qin Liu, Xiangfan Yin, Katherine L. Nathanson, Meenhard Herlyn, Adina Vultur

Published Jul 19, 2016 · Vol. 7, No. 34 · pp. 54897-54912

Imatinib in systemic mastocytosis: a phase IV clinical trial in patients lacking exon 17 KIT mutations and review of the literature Clinical Research Papers

IvÃ¡n Alvarez-Twose, Almudena Matito, JosÃ© MÃ¡rio Morgado, Laura SÃ¡nchez- MuÃ±oz, MarÃa Jara-Acevedo, AndrÃ©s GarcÃa-Montero, Andrea Mayado, Carolina Caldas, Cristina TeodÃ³sio, Javier Ignacio MuÃ±oz-GonzÃ¡lez, Manuela Mollejo, Luis Escribano, Alberto Orfao

Published Jul 19, 2016 · Vol. 8, No. 40 · pp. 68950-68963

Gene mutations and actionable genetic lesions in mantle cell lymphoma Review

Makhdum Ahmed, Leo Zhang, Krystle Nomie, Laura Lam, Michael Wang

Published Jul 19, 2016 · Vol. 7, No. 36 · pp. 58638-58648

IL-17A exacerbates cisplatin-based resistance of OVCA via upregulating the expression of ABCG2 and MDR1 through Gli1-mediated Hh signaling Research Paper

Xiulong Niu, Wenxing Liu, Yue Wang, Xiaomei Liu, Hongjian Zhang, Zhijun Li, Hongzhao Li, Yoichiro Iwakura, Weimin Deng

Published Jul 18, 2016 · Vol. 5

miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways Research Paper

Xiaoyan Sun, Jun Li, Yanhong Sun, Yi Zhang, Liyun Dong, Chen Shen, Liu Yang, Ming Yang, Yan Li, Guanxin Shen, Yating Tu, Juan Tao

Published Jul 18, 2016 · Vol. 7, No. 33 · pp. 53558-53570

Pregnane X-receptor promotes stem cell-mediated colon cancer relapse Research Paper

Chris Planque, Fatemeh Rajabi, Fanny Grillet, Pascal Finetti, FranÃ§ois Bertucci, Meritxell Gironella, Juan JosÃ© Lozano, Bertrand Beucher, Julie Giraud, VÃ©ronique Garambois, Charles Vincent, Daniel Brown, Ludovic Caillo, Jovana Kantar, AndrÃ© Pelegrin, Michel Prudhomme, JÃ©rÃ©mie Ripoche, Jean FranÃ§ois Bourgaux, Christophe Ginestier, Antoni Castells, FrÃ©dÃ©ric Hollande, Julie Pannequin, Jean Marc Pascussi

Published Jul 18, 2016 · Vol. 7, No. 35 · pp. 56558-56573

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules Research Paper

Jee Hye Kim, Ye Jin Jung, Byeol Choi, Na Lim Lee, Hae Jun Lee, Soo Yeon Kwak, Youngjoo Kwon, Younghwa Na, Yun-Sil Lee

Published Jul 16, 2016 · Vol. 7, No. 33 · pp. 53178-53190

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer Research Paper

Callie R. Merry, Sarah McMahon, Megan E. Forrest, Cynthia F. Bartels, Alina Saiakhova, Courtney A. Bartel, Peter C. Scacheri, Cheryl L. Thompson, Mark W. Jackson, Lyndsay N. Harris, Ahmad M. Khalil

Published Jul 16, 2016 · Vol. 7, No. 33 · pp. 53230-53244

Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer Research Paper

Sidney W. Fu, Saurabh P. Kirolikar, Erika Ginsburg, Xiaohui Tan, Arnold Schwartz, Samuel J. Simmens, Yan-Gao Man, Joseph J. Pinzone, Christine Teal, Sanket Awate, Barbara K. Vonderhaar, Patricia E. Berg

Published Jul 16, 2016 · Vol. 7, No. 33 · pp. 53204-53216

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia Research Paper

Chiara Palmi, Angela M. Savino, Daniela Silvestri, Ilaria Bronzini, Gunnar Cario, Maddalena Paganin, Barbara Buldini, Marta Galbiati, Martina U. Muckenthaler, Cristina Bugarin, Pamela Della Mina, Stefan Nagel, Elena Barisone, Fiorina Casale, Franco Locatelli, Luca Lo Nigro, Concetta Micalizzi, Rosanna Parasole, Andrea Pession, Maria C. Putti, Nicola Santoro, Anna M. Testi, Ottavio Ziino, Andreas E. Kulozik, Martin Zimmermann, Martin Schrappe, Antonello Villa, Giuseppe Gaipa, Giuseppe Basso, Andrea Biondi, Maria G. Valsecchi, Martin Stanulla, Valentino Conter, Geertruy te Kronnie, Giovanni Cazzaniga

Published Jul 15, 2016 · Vol. 7, No. 37 · pp. 59260-59272

Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling Research Paper

Juan Du, Jinfeng Wu, Xiuqiong Fu, Anfernee Kai-Wing Tse, Ting Li, Tao Su, Zhi-ling Yu

Published Jul 13, 2016 · Vol. 7, No. 32 · pp. 52218-52229

Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Ai N.H. Phan, Tuyen N.M. Hua, Min-Kyu Kim, Vu T.A. Vo, Jong-Whan Choi, Hyun-Won Kim, Jin Kyung Rho, Ki Woo Kim, Yangsik Jeong

Published Jul 13, 2016 · Vol. 7, No. 34 · pp. 54702-54713

DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma Research Paper

Sheila Mansouri, Sanjay Singh, Amir Alamsahebpour, Kelly Burrell, Mira Li, Merve Karabork, Can Ekinci, Elizabeth Koch, Ihsan Solaroglu, Jeffery T. Chang, Bradly Wouters, Kenneth Aldape, Gelareh Zadeh

Published Jul 13, 2016 · Vol. 7, No. 35 · pp. 56431-56446

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma Research Paper

Giuliana Cavalloni, Caterina Peraldo-Neia, Chiara Varamo, Giovanna Chiorino, Francesco Sassi, Massimo Aglietta, Francesco Leone

Published Jul 13, 2016 · Vol. 7, No. 32 · pp. 52354-52363

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia Research Paper

Kamilla M.E. Laidlaw, Samuel Berhan, Suhu Liu, Giovannino Silvestri, Tessa L. Holyoake, David A. Frank, Bharat Aggarwal, Michael Y. Bonner, Danilo Perrotti, Heather G. JÃ¸rgensen, Jack L. Arbiser

Published Jul 12, 2016 · Vol. 7, No. 32 · pp. 51651-51664

PIP₃-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans Priority Research Paper

Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Jay Johnson, Ramani Alla, Samuel G. Mackintosh, Robert J. Shmookler Reis

Published Jul 12, 2016 · Vol. 7, No. 31 · pp. 48870-48886

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

Lara Paracchini, Laura Mannarino, Ilaria Craparotta, Chiara Romualdi, Robert Fruscio, Tommaso Grassi, Vittoria Fotia, Giulia Caratti, Patrizia Perego, Enrica Calura, Luca Clivio, Maurizio D’Incalci, Luca Beltrame, Sergio Marchini

Published Jul 9, 2016 · Vol. 12, No. 24 · pp. 2404-2417

Keywords: ovarian cancer, temporal heterogeneity, spatial heterogeneity, targeted next generation sequencing, drug resistance

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer Research Paper

Hui Pan, Tao Jiang, Ningning Cheng, Qi Wang, Shengxiang Ren, Xuefei Li, Chao Zhao, Limin Zhang, Weijing Cai, Caicun Zhou

Published Jul 9, 2016 · Vol. 7, No. 31 · pp. 49948-49960

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels Research Paper

Julien Beyrath, Neila Chekkat, Cristian R. Smulski, Caterina M. Lombardo, Marie-Charlotte Lechner, Cendrine Seguin, Marion Decossas, Maria Vittoria Spanedda, BenoÃ®t Frisch, Gilles Guichard, Sylvie Fournel

Published Jul 9, 2016 · Vol. 7, No. 40 · pp. 64942-64956

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2 Research Paper

PIM kinases as therapeutic targets against advanced melanoma Research Paper

Imatinib in systemic mastocytosis: a phase IV clinical trial in patients lacking exon 17 KIT mutations and review of the literature Clinical Research Papers

Gene mutations and actionable genetic lesions in mantle cell lymphoma Review

IL-17A exacerbates cisplatin-based resistance of OVCA via upregulating the expression of ABCG2 and MDR1 through Gli1-mediated Hh signaling Research Paper

miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways Research Paper

Pregnane X-receptor promotes stem cell-mediated colon cancer relapse Research Paper

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules Research Paper

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer Research Paper

Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer Research Paper

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia Research Paper

Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling Research Paper

Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma Research Paper

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma Research Paper

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia Research Paper

PIP₃-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans Priority Research Paper

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer Research Paper

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2 Research Paper

PIM kinases as therapeutic targets against advanced melanoma Research Paper

Imatinib in systemic mastocytosis: a phase IV clinical trial in patients lacking exon 17 KIT mutations and review of the literature Clinical Research Papers

Gene mutations and actionable genetic lesions in mantle cell lymphoma Review

IL-17A exacerbates cisplatin-based resistance of OVCA via upregulating the expression of ABCG2 and MDR1 through Gli1-mediated Hh signaling Research Paper

miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways Research Paper

Pregnane X-receptor promotes stem cell-mediated colon cancer relapse Research Paper

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules Research Paper

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer Research Paper

Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer Research Paper

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia Research Paper

Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling Research Paper

Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma Research Paper

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma Research Paper

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia Research Paper

PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans Priority Research Paper

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer Research Paper

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels Research Paper

PIP₃-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans Priority Research Paper