The Oncosearch | Oncotarget

Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin Clinical Research Papers

Michael J. Overman, Van Morris, Helen Moinova, Ganiraju Manyam, Joe Ensor, Michael S. Lee, Cathy Eng, Bryan Kee, David Fogelman, Rachna T. Shroff, Thomas LaFramboise, Thibault Mazard, Tian Feng, Stanley Hamilton, Bradley Broom, James Lutterbaugh, Jean-Pierre Issa, Sanford D. Markowitz, Scott Kopetz

Published Aug 16, 2016 · Vol. 7, No. 41 · pp. 67495-67506

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds Priority Research Paper

Diego Carrella, Isabella Manni, Barbara Tumaini, Rosanna Dattilo, Federica Papaccio, Margherita Mutarelli, Francesco Sirci, Carla A. Amoreo, Marcella Mottolese, Manuela Iezzi, Laura Ciolli, Valentina Aria, Roberta Bosotti, Antonella Isacchi, Fabrizio Loreni, Alberto Bardelli, Vittorio E. Avvedimento, Diego di Bernardo, Luca Cardone

Published Aug 16, 2016 · Vol. 7, No. 37 · pp. 58743-58758

MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy Research Paper

XiaoRong Zhong, GuiQin Xie, Zhang Zhang, Zhu Wang, Yu Wang, YanPing Wang, Yan Qiu, Li Li, Hong Bu, JiaYuan Li, Hong Zheng

Published Aug 13, 2016 · Vol. 7, No. 38 · pp. 61166-61182

The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer Research Paper

Mei-Ren Pan, Ming-Chuan Hsu, Chi-Wen Luo, Li-Tzong Chen, Yan-Shen Shan, Wen-Chun Hung

Published Aug 12, 2016 · Vol. 7, No. 38 · pp. 61136-61151

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing Research Paper

Ying Jin, Yang Shao, Xun Shi, Guangyuan Lou, Yiping Zhang, Xue Wu, Xiaoling Tong, Xinmin Yu

Published Aug 12, 2016 · Vol. 7, No. 38 · pp. 61755-61763

Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension Research Paper

Andreia Peixoto, Elisabete Fernandes, Cristiana Gaiteiro, LuÃs Lima, Rita Azevedo, Janine Soares, Sofia Cotton, Beatriz Parreira, Manuel Neves, Teresina Amaro, Ana Tavares, Filipe Teixeira, Carlos Palmeira, Maria Rangel, AndrÃ© M.N. Silva, Celso A. Reis, LÃºcio Lara Santos, Maria JosÃ© Oliveira, JosÃ© Alexandre Ferreira

Published Aug 12, 2016 · Vol. 7, No. 39 · pp. 63138-63157

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice Research Paper

Jian Hong, Yimin Jia, Shifeng Pan, Longfi Jia, Huifang Li, Zhenqiang Han, Demin Cai, Ruqian Zhao

Published Aug 12, 2016 · Vol. 7, No. 35 · pp. 56071-56082

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

Phaik Ju Teoh, Chonglei Bi, Chirackal Sintosebastian, Liang Seah Tay, Rafael Fonseca, Wee Joo Chng

Published Aug 12, 2016 · Vol. 7, No. 38 · pp. 61806-61819

Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus Research Paper

Eric Hastie, Marcela Cataldi, Megan J. Moerdyk-Schauwecker, SÃ©bastien A. Felt, Nury Steuerwald, Valery Z. Grdzelishvili

Published Aug 11, 2016 · Vol. 7, No. 38 · pp. 61601-61618

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia Priority Research Paper

Babasaheb D. Yadav, Amy L. Samuels, Julia E. Wells, Rosemary Sutton, Nicola C. Venn, Katerina Bendak, Denise Anderson, Glenn M. Marshall, Catherine H. Cole, Alex H. Beesley, Ursula R. Kees, Richard B. Lock

Published Aug 11, 2016 · Vol. 7, No. 37 · pp. 58728-58742

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2 Research Paper

Subramanian Venkatesan, Marlous Hoogstraat, Ester Caljouw, Tessa Pierson, Jochem K.H. Spoor, Lona Zeneyedpour, Hendrikus J. Dubbink, Lennard J. Dekker, MariÃ«lle van der Kaaij, Jenneke Kloezeman, Lotte M.E. Berghauser Pont, Nicolle J.M. Besselink, Theo M. Luider, Jos Joore, John W. Martens, Martine L.M. Lamfers, Stefan Sleijfer, Sieger Leenstra

Published Aug 11, 2016 · Vol. 7, No. 36 · pp. 58435-58444

Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival Research Paper

Chun-Hua Dai, Ping Chen, Jian Li, Tin Lan, Yong-Chang Chen, Hai Qian, Kang Chen, Mei-Yu Li

Published Aug 11, 2016 · Vol. 7, No. 40 · pp. 65157-65170

Sensitivity to PRIMA-1^MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status Research Paper

Mariia Patyka, Zeinab Sharifi, Kevin Petrecca, Jose Mansure, Bertrand Jean-Claude, Siham Sabri

Published Aug 11, 2016 · Vol. 7, No. 37 · pp. 60245-60269

Clinical outcomes of advanced non-small-cell lung cancer patients with EGFR mutation, ALK rearrangement and EGFR/ALK co-alterations Research Paper

Na-Na Lou, Xu-Chao Zhang, Hua-Jun Chen, Qing Zhou, Li-Xu Yan, Zhi Xie, Jian Su, Zhi-Hong Chen, Hai-Yan Tu, Hong-Hong Yan, Zhen Wang, Chong-Rui Xu, Ben-Yuan Jiang, Bin-Chao Wang, Xiao-Yan Bai, Wen-Zhao Zhong, Yi-Long Wu, Jin-Ji Yang

Published Aug 11, 2016 · Vol. 7, No. 40 · pp. 65185-65195

Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer Research Paper

Xiao-Feng Wang, Xiao-Wei Zhang, Rui-Xi Hua, Yi-Qun Du, Ming-Zhu Huang, Yong Liu, Yu Fang Cheng, Wei-Jian Guo

Published Aug 11, 2016 · Vol. 7, No. 39 · pp. 63352-63361

CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy Research Paper

Ilya V. Ulasov, Natalya V. Kaverina, Dhimankrishna Ghosh, Marya A. Baryshnikova, Zaira G. Kadagidze, Apollon I. Karseladze, Anatoly Y. Baryshnikov, Charles S. Cobbs

Published Aug 10, 2016 · Vol. 8, No. 16 · pp. 25989-25999

BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration Research Paper

Published Aug 10, 2016 · Vol. 7, No. 35 · pp. 55957-55969

ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance Research Paper

Nadine LÃ¶schmann, Martin Michaelis, Florian Rothweiler, Yvonne Voges, Barbora BalÃ³novÃ¡, Barry A. Blight, Jindrich Cinatl Jr

Published Aug 9, 2016 · Vol. 7, No. 36 · pp. 58051-58064

CD164 promotes lung tumor-initiating cells with stem cell activity and determines tumor growth and drug resistance via Akt/mTOR signaling Research Paper

Wei-Liang Chen, Ai-Fang Huang, Shih-Ming Huang, Ching-Liang Ho, Yung-Lung Chang, James Yi-Hsin Chan

Published Aug 9, 2016 · Vol. 8, No. 33 · pp. 54115-54135

Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer Research Paper

Tejal Joshi, Daniel Elias, Jan Stenvang, Carla L. Alves, Fei Teng, Maria B. Lyng, Anne E. Lykkesfeldt, Nils BrÃ¼nner, Jun Wang, Ramneek Gupta, Christopher T. Workman, Henrik J. Ditzel

Published Aug 9, 2016 · Vol. 7, No. 35 · pp. 57239-57253

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Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin Clinical Research Papers

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds Priority Research Paper

MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy Research Paper

The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer Research Paper

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing Research Paper

Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension Research Paper

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice Research Paper

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus Research Paper

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia Priority Research Paper

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2 Research Paper

Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival Research Paper

Sensitivity to PRIMA-1^MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status Research Paper

Clinical outcomes of advanced non-small-cell lung cancer patients with EGFR mutation, ALK rearrangement and EGFR/ALK co-alterations Research Paper

Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer Research Paper

CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy Research Paper

BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration Research Paper

ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance Research Paper

CD164 promotes lung tumor-initiating cells with stem cell activity and determines tumor growth and drug resistance via Akt/mTOR signaling Research Paper

Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin Clinical Research Papers

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds Priority Research Paper

MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy Research Paper

The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer Research Paper

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing Research Paper

Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension Research Paper

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice Research Paper

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus Research Paper

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia Priority Research Paper

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2 Research Paper

Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival Research Paper

Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status Research Paper

Clinical outcomes of advanced non-small-cell lung cancer patients with EGFR mutation, ALK rearrangement and EGFR/ALK co-alterations Research Paper

Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer Research Paper

CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy Research Paper

BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration Research Paper

ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance Research Paper

CD164 promotes lung tumor-initiating cells with stem cell activity and determines tumor growth and drug resistance via Akt/mTOR signaling Research Paper

Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer Research Paper

Sensitivity to PRIMA-1^MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status Research Paper