The Oncosearch | Oncotarget

Cancer stem cells (CSCs), cervical CSCs and targeted therapies Review

Ruixia Huang, Einar K. Rofstad

Published Jun 19, 2016 · Vol. 8, No. 21 · pp. 35351-35367

MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity Research Paper

Yang Wang, Ning Shao, Xueying Mao, Minmin Zhu, Weifei Fan, Zhixiang Shen, Rong Xiao, Chuncai Wang, Wenping Bao, Xinyu Xu, Chun Yang, Jian Dong, Deshui Yu, Yan Wu, Caixia Zhu, Liting Wen, Xiaojie Lu, Yong-Jie Lu, Ninghan Feng

Published Jun 18, 2016 · Vol. 7, No. 30 · pp. 47444-47464

Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling Research Paper

Chong Zhang, Mengzhi Wu, Lizhen Zhang, Li-Ru Shang, Jian-Hong Fang, Shi-Mei Zhuang

Published Jun 18, 2016 · Vol. 7, No. 29 · pp. 45702-45714

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca²⁺ release Research Paper

Chenghui Liao, Kai Zheng, Yan Li, Hong Xu, Qiangrong Kang, Long Fan, Xiaopeng Hu, Zhe Jin, Yong Zeng, Xiaoli Kong, Jian Zhang, Xuli Wu, Haiqiang Wu, Lizhong Liu, Xiaohua Xiao, Yifei Wang, Zhendan He

Published Jun 18, 2016 · Vol. 7, No. 30 · pp. 47387-47402

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells Research Paper

Clarissa Ribeiro Reily Rocha, Gustavo Satoru Kajitani, Annabel Quinet, Rodrigo Soares Fortunato, Carlos Frederico Martins Menck

Published Jun 17, 2016 · Vol. 7, No. 30 · pp. 48081-48092

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells Research Paper

Fangli Chen, Yuichi Ishikawa, Akimi Akashi, Tomoki Naoe, Hitoshi Kiyoi

Published Jun 17, 2016 · Vol. 7, No. 30 · pp. 47018-47032

Tracing the origin of Treponema pallidum in China using next-generation sequencing Research Paper

Jun Sun, Zhefeng Meng, Kaiqi Wu, Biao Liu, Sufang Zhang, Yudan Liu, Yuezhu Wang, Huajun Zheng, Jian Huang, Pingyu Zhou

Published Jun 17, 2016 · Vol. 7, No. 28 · pp. 42904-42918

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer Research Paper

Hiroaki Ono, Marc D. Basson, Hiromichi Ito

Published Jun 17, 2016 · Vol. 7, No. 32 · pp. 51301-51310

Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer Research Paper

James B. Greenaway, Carl Virtanen, Kata Osz, Tamas Revay, Daniel Hardy, Trevor Shepherd, Gabriel DiMattia, Jim Petrik

Published Jun 17, 2016 · Vol. 7, No. 30 · pp. 47343-47365

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis Research Paper

Asaha Fujimoto, Kei Kawana, Ayumi Taguchi, Katsuyuki Adachi, Masakazu Sato, Hiroe Nakamura, Juri Ogishima, Mitsuyo Yoshida, Tomoko Inoue, Haruka Nishida, Kensuke Tomio, Aki Yamashita, Yoko Matsumoto, Takahide Arimoto, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii

Published Jun 17, 2016 · Vol. 7, No. 32 · pp. 51854-51864

Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer Research Paper

Theodoros Karantanos, Styliani Karanika, Jianxiang Wang, Guang Yang, Masato Dobashi, Sanghee Park, Chengzhen Ren, Likun Li, Spyridon P. Basourakos, Anh Hoang, Eleni Efstathiou, Xuemei Wang, Patricia Troncoso, Mark Titus, Bradley Broom, Jeri Kim, Paul G. Corn, Christopher J. Logothetis, Timothy C. Thompson

Published Jun 16, 2016 · Vol. 7, No. 29 · pp. 46321-46334

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer Research Paper

Alessia Lopergolo, Rosalba Perrone, Monica Tortoreto, Filippo Doria, Giovanni L. Beretta, Valentina Zuco, Mauro Freccero, Maria Grazia Borrello, Cinzia Lanzi, Sara N. Richter, Nadia Zaffaroni, Marco Folini

Published Jun 16, 2016 · Vol. 7, No. 31 · pp. 49649-49663

Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells Research Paper

Amruta Ronghe, Anwesha Chatterjee, Nimee K. Bhat, Subhash Padhye, Hari K. Bhat

Published Jun 16, 2016 · Vol. 7, No. 32 · pp. 51747-51762

TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation Research Paper

Catherine J. Drummond, Arman Esfandiari, Junfeng Liu, Xiaohong Lu, Claire Hutton, Jennifer Jackson, Karim Bennaceur, Qing Xu, Aditya Rao Makimanejavali, Fabio Del Bello, Alessandro Piergentili, David R. Newell, Ian R. Hardcastle, Roger J. Griffin, John Lunec

Published Jun 15, 2016 · Vol. 7, No. 29 · pp. 46203-46218

Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer Research Paper

Oscar Aguilera, MarÃa MuÃ±oz-Sagastibelza, Blanca TorrejÃ³n, Aurea Borrero-Palacios, Laura del Puerto-Nevado, Javier MartÃnez-Useros, MarÃa Rodriguez-Remirez, Sandra Zazo, Estela GarcÃa, Mario Fraga, Federico Rojo, JesÃºs GarcÃa-Foncillas

Published Jun 15, 2016 · Vol. 7, No. 30 · pp. 47954-47965

Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma Research Paper

Xing-gang Mao, Chao Wang, Dong-ye Liu, Xiang Zhang, Liang Wang, Ming Yan, Wei Zhang, Jun Zhu, Zi-chao Li, Chen Mi, Jing-yang Tian, Guang-dong Hou, Si-yu Miao, Zi-xuan Song, Jin-cheng Li, Xiao-yan Xue

Published Jun 14, 2016 · Vol. 7, No. 30 · pp. 47808-47820

Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy Research Paper

Xuechao Wan, Honglei Pu, Wenhua Huang, Shu Yang, Yalong Zhang, Zhe Kong, Zhuoran Yang, Peiqing Zhao, Ao Li, Tao Li, Yao Li

Published Jun 14, 2016 · Vol. 7, No. 32 · pp. 51284-51300

Androgen receptor activity modulates responses to cisplatin treatment in bladder cancer Research Paper

Eiji Kashiwagi, Hiroki Ide, Satoshi Inoue, Takashi Kawahara, Yichun Zheng, Leonardo O. Reis, Alexander S. Baras, Hiroshi Miyamoto

Published Jun 14, 2016 · Vol. 7, No. 31 · pp. 49169-49179

Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway Research Paper

Xinyou Xie, Huixing Liu, Yanzhong Wang, Yanwen Zhou, Haitao Yu, Guiling Li, Zhi Ruan, Fengying Li, Xiuhong Wang, Jun Zhang

Published Jun 13, 2016 · Vol. 7, No. 29 · pp. 45837-45848

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells Research Paper

Yi Huo, Zhiguo Zheng, Yuling Chen, Qingtao Wang, Zhenyu Zhang, Haiteng Deng

Published Jun 13, 2016 · Vol. 7, No. 29 · pp. 45876-45888

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Cancer stem cells (CSCs), cervical CSCs and targeted therapies Review

MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity Research Paper

Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling Research Paper

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca²⁺ release Research Paper

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells Research Paper

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells Research Paper

Tracing the origin of Treponema pallidum in China using next-generation sequencing Research Paper

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer Research Paper

Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer Research Paper

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis Research Paper

Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer Research Paper

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer Research Paper

Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells Research Paper

TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation Research Paper

Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer Research Paper

Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma Research Paper

Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy Research Paper

Androgen receptor activity modulates responses to cisplatin treatment in bladder cancer Research Paper

Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway Research Paper

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Cancer stem cells (CSCs), cervical CSCs and targeted therapies Review

MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity Research Paper

Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling Research Paper

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release Research Paper

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells Research Paper

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells Research Paper

Tracing the origin of Treponema pallidum in China using next-generation sequencing Research Paper

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer Research Paper

Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer Research Paper

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis Research Paper

Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer Research Paper

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer Research Paper

Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells Research Paper

TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation Research Paper

Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer Research Paper

Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma Research Paper

Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy Research Paper

Androgen receptor activity modulates responses to cisplatin treatment in bladder cancer Research Paper

Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway Research Paper

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells Research Paper

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca²⁺ release Research Paper