The Oncosearch | Oncotarget

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Yi-Nan Liu, Tzu-Hua Chang, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hsiu Tsai, Hsuan-Yu Chen, Sung-Liang Yu, James Chih-Hsin Yang, Jin-Yuan Shih

Published Mar 18, 2015 · Vol. 6, No. 12 · pp. 10415-10431

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

Andreas D. Ã˜rskov, Marianne B. Treppendahl, Anni Skovbo, Mette S. Holm, Lone S. Friis, Marianne Hokland, Kirsten GrÃ¸nbÃ¦k

Published Mar 18, 2015 · Vol. 6, No. 11 · pp. 9612-9626

Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats Priority Research Paper

Verena Staedtke, Ren-Yuan Bai, Weiyun Sun, Judy Huang, Kathleen Kazuko Kibler, Betty M. Tyler, Gary L. Gallia, Kenneth Kinzler, Bert Vogelstein, Shibin Zhou, Gregory J. Riggins

Published Mar 18, 2015 · Vol. 6, No. 8 · pp. 5536-5546

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

Ayako Nogami, Gaku Oshikawa, Keigo Okada, Shusaku Fukutake, Yoshihiro Umezawa, Toshikage Nagao, Tetsuya Kurosu, Osamu Miura

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9189-9205

Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib Research Paper

Shengzhi Xie, Yongwu Li, Xiaoyan Li, Linxiong Wang, Na Yang, Yadi Wang, Huafeng Wei

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9206-9219

ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer Research Paper

Anke Bill, Abraham Gutierrez, Sucheta Kulkarni, Carolyn Kemp, Debora Bonenfant, Hans Voshol, Umamaheswar Duvvuri, L. Alex Gaither

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9173-9188

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15 Research Paper

Ningning Li, Federica Lorenzi, Eliana Kalakouti, Makhliyo Normatova, Roya Babaei-Jadidi, Ian Tomlinson, Abdolrahman S. Nateri

Published Mar 16, 2015 · Vol. 6, No. 11 · pp. 9240-9256

Inhibition of the HER2-YB1-AR axis with Lapatinib synergistically enhances Enzalutamide anti-tumor efficacy in castration resistant prostate cancer Research Paper

Masaki Shiota, Jennifer L. Bishop, Ario Takeuchi, Ka Mun Nip, Thomas Cordonnier, Eliana Beraldi, Hidetoshi Kuruma, Martin E. Gleave, Amina Zoubeidi

Published Mar 15, 2015 · Vol. 6, No. 11 · pp. 9086-9098

Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the Î²-catenin/TCF complex association via FOXO3a activation Research Paper

Yue Zhou, Chao Liang, Fei Xue, Wei Chen, Xiao Zhi, Xinhua Feng, Xueli Bai, Tingbo Liang

Published Mar 14, 2015 · Vol. 6, No. 12 · pp. 10350-10365

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer Research Paper

Friederike Braig, Manuela MÃ¤rz, Aneta Schieferdecker, Alexander Schulte, Mareike Voigt, Alexander Stein, Tobias Grob, Malik Alawi, Daniela Indenbirken, Malte Kriegs, Erik Engel, Udo Vanhoefer, Adam Grundhoff, Sonja Loges, Kristoffer Riecken, Boris Fehse, Carsten Bokemeyer, Mascha Binder

Published Mar 14, 2015 · Vol. 6, No. 14 · pp. 12035-12047

The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor Research Paper

Huey-En Tzeng, Lixin Yang, Kemin Chen, Yafan Wang, Yun-Ru Liu, Shiow-Lin Pan, Shikha Gaur, Shuya Hu, Yun Yen

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11061-11073

Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells Research Paper

Moitza Principe, Patrizia Ceruti, Neng-Yao Shih, Michelle S. Chattaragada, Simona Rolla, Laura Conti, Marco Bestagno, Lorena Zentilin, Sheng-Hui Yang, Paola Migliorini, Paola Cappello, Oscar Burrone, Francesco Novelli

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11098-11113

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Research Paper

Lahiru Gangoda, Shivakumar Keerthikumar, Pamali Fonseka, Laura E. Edgington, Ching-Seng Ang, Cemil Ozcitti, Matthew Bogyo, Belinda S. Parker, Suresh Mathivanan

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11175-11190

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma Research Paper

Anna Granata, Roberta Nicoletti, Paola Perego, Egidio Iorio, Balaji Krishnamachary, Fabio Benigni, Alessandro Ricci, Franca Podo, Zaver M. Bhujwalla, Silvana Canevari, Marina Bagnoli, Delia Mezzanzanica

Published Mar 14, 2015 · Vol. 6, No. 13 · pp. 11216-11230

Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer Research Paper

Yan Gao, Rosemary Foster, Xiaoqian Yang, Yong Feng, Jacson K. Shen, Henry J. Mankin, Francis J. Hornicek, Mansoor M. Amiji, Zhenfeng Duan

Published Mar 13, 2015 · Vol. 6, No. 11 · pp. 9313-9326

Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer Research Paper

Ping Chen, Tao Hu, Yupei Liang, Yanan Jiang, Yongfu Pan, Chunjie Li, Ping Zhang, Dongping Wei, Pei Li, Lak Shin Jeong, Yiwei Chu, Hui Qi, Meng Yang, Robert M. Hoffman, Ziming Dong, Lijun Jia

Published Mar 13, 2015 · Vol. 6, No. 11 · pp. 9002-9017

PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins Research Paper

Valentina Zuco, Michelandrea De Cesare, Nadia Zaffaroni, Cinzia Lanzi, Giuliana Cassinelli

Published Mar 12, 2015 · Vol. 6, No. 11 · pp. 8736-8749

Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel Research Paper

Pedram Kharaziha, Dimitris Chioureas, Dorothea Rutishauser, George Baltatzis, Lena Lennartsson, Pedro Fonseca, Alireza Azimi, Kjell Hultenby, Roman Zubarev, Anders UllÃ©n, Jeffrey Yachnin, Sten Nilsson, Theocharis Panaretakis

Published Mar 12, 2015 · Vol. 6, No. 25 · pp. 21740-21754

Therapy of prostate cancer using a novel cancer terminator virus and a small molecule BH-3 mimetic Priority Research Paper

Siddik Sarkar, Bridget A. Quinn, Xue-Ning Shen, Rupesh Dash, Swadesh K. Das, Luni Emdad, Alexander L. Klibanov, Xiang-Yang Wang, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher

Published Mar 12, 2015 · Vol. 6, No. 13 · pp. 10712-10727

MiR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2 Research Paper

Hongzhan Liao, Yifeng Bai, Shengcong Qiu, Lei Zheng, Lianyan Huang, Tianzhu Liu, Xin Wang, Yanting Liu, Ningbo Xu, Xiaohui Yan, Hongbo Guo

Published Mar 12, 2015 · Vol. 6, No. 11 · pp. 8914-8928

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IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats Priority Research Paper

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib Research Paper

ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer Research Paper

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15 Research Paper

Inhibition of the HER2-YB1-AR axis with Lapatinib synergistically enhances Enzalutamide anti-tumor efficacy in castration resistant prostate cancer Research Paper

Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the Î²-catenin/TCF complex association via FOXO3a activation Research Paper

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer Research Paper

The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor Research Paper

Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells Research Paper

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Research Paper

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma Research Paper

Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer Research Paper

Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer Research Paper

PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins Research Paper

Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel Research Paper

Therapy of prostate cancer using a novel cancer terminator virus and a small molecule BH-3 mimetic Priority Research Paper

MiR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer Research Paper

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation Clinical Research Papers

Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats Priority Research Paper

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia Research Paper

Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib Research Paper

ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer Research Paper

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15 Research Paper

Inhibition of the HER2-YB1-AR axis with Lapatinib synergistically enhances Enzalutamide anti-tumor efficacy in castration resistant prostate cancer Research Paper

Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the Î²-catenin/TCF complex association via FOXO3a activation Research Paper

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer Research Paper

The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: resistance reversal with WNT inhibitor Research Paper

Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells Research Paper

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin Research Paper

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma Research Paper

Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer Research Paper

Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer Research Paper

PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins Research Paper

Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel Research Paper

Therapy of prostate cancer using a novel cancer terminator virus and a small molecule BH-3 mimetic Priority Research Paper

MiR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2 Research Paper