The Oncosearch | Oncotarget

Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancer Research Paper

Shu Xia, Manish Kohli, Meijun Du, Rachel L. Dittmar, Adam Lee, Debashis Nandy, Tiezheng Yuan, Yongchen Guo, Yuan Wang, Michael R. Tschannen, Elizabeth Worthey, Howard Jacob, William See, Deepak Kilari, Xuexia Wang, Raymond L. Hovey, Chiang-Ching Huang, Liang Wang

Published Apr 15, 2015 · Vol. 6, No. 18 · pp. 16411-16421

Erratum: Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms Errata

Jahangir Abdi, Guoan Chen, Hong Chang

Published Apr 14, 2015 · Vol. 6, No. 10 · pp. 7364

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Jian-Ge Qiu, Yao-Jun Zhang, Yong Li, Jin-Ming Zhao, Wen-Ji Zhang, Qi-Wei Jiang, Xiao-Long Mei, You-Qiu Xue, Wu-Ming Qin, Yang Yang, Di-Wei Zheng, Yao Chen, Meng-Ning Wei, Zhi Shi

Published Apr 14, 2015 · Vol. 6, No. 17 · pp. 15494-15509

Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer Research Paper

Bente Bull-Hansen, Maria B. Berstad, Kristian Berg, Yu Cao, Ellen Skarpen, Ane Sofie Fremstedal, Michael G. Rosenblum, Qian Peng, Anette Weyergang

Published Apr 14, 2015 · Vol. 6, No. 14 · pp. 12436-12451

Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer Priority Research Paper

Agnieszka K. Witkiewicz, Nicholas A. Borja, Jorge Franco, Jonathan R. Brody, Charles J. Yeo, John Mansour, Michael A. Choti, Peter McCue, Erik S. Knudsen

Published Apr 14, 2015 · Vol. 6, No. 18 · pp. 15788-15801

Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells Priority Research Paper

Maria Peiris-PagÃ¨s, Federica Sotgia, Michael P. Lisanti

Published Apr 14, 2015 · Vol. 6, No. 13 · pp. 10728-10745

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

Xiaoqing Jia, Qi Hong, Li Lei, Daqiang Li, Jianwei Li, Miao Mo, Yujie Wang, Zhimin Shao, Zhenzhou Shen, Jingyi Cheng, Guangyu Liu

Published Apr 13, 2015 · Vol. 6, No. 11 · pp. 8648-8662

Epithelial to mesenchymal transition is associated with rapamycin resistance Research Paper

Ashley M. Holder, Argun Akcakanat, Farrell Adkins, Kurt Evans, Huiqin Chen, Caimiao Wei, Denai R. Milton, Yisheng Li, Kim-Anh Do, Filip Janku, Funda Meric-Bernstam

Published Apr 13, 2015 · Vol. 6, No. 23 · pp. 19500-19513

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression Research Paper

Germano Mariano, Maria Rosaria Ricciardi, Daniela Trisciuoglio, Michele Zampieri, Fabio Ciccarone, Tiziana Guastafierro, Roberta Calabrese, Elisabetta Valentini, Agostino Tafuri, Donatella Del Bufalo, Paola Caiafa, Anna Reale

Published Apr 13, 2015 · Vol. 6, No. 17 · pp. 15008-15021

Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort Clinical Research Papers

Kwan-Hwa Chi, Hui-Ling Ko, Kai-Lin Yang, Cheng-Yen Lee, Mau-Shin Chi, Shang-Jyh Kao

Published Apr 12, 2015 · Vol. 6, No. 18 · pp. 16735-16745

FGF23 is elevated in multiple myeloma and increases heparanase expression by tumor cells Research Paper

Attaya Suvannasankha, Douglas R. Tompkins, Daniel F. Edwards, Katarina V. Petyaykina, Colin D. Crean, Pierrick G. Fournier, Jamie M. Parker, George E. Sandusky, Shoji Ichikawa, Erik A. Imel, John M. Chirgwin

Published Apr 12, 2015 · Vol. 6, No. 23 · pp. 19647-19660

Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma Research Paper

Prahlad V. Raninga, Giovanna Di Trapani, Slavica Vuckovic, Maneet Bhatia, Kathryn F. Tonissen

Published Apr 12, 2015 · Vol. 6, No. 17 · pp. 15410-15424

MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma Research Paper

Juan Du, Shuyan Liu, Jie He, Xi Liu, Ying Qu, Wenqing Yan, Jianling Fan, Rong Li, Hao Xi, Weijun Fu, Chunyang Zhang, Jing Yang, Jian Hou

Published Apr 12, 2015 · Vol. 6, No. 17 · pp. 14993-15007

NHE9 induces chemoradiotherapy resistance in esophageal squamous cell carcinoma by upregulating the Src/Akt/Î²-catenin pathway and Bcl-2 expression Research Paper

Junying Chen, Hong Yang, Jing Wen, Kongjia Luo, Qianwen Liu, Yijie Huang, Yuzhen Zheng, Zihui Tan, Qinyuan Huag, Jianhua Fu

Published Apr 10, 2015 · Vol. 6, No. 14 · pp. 12405-12420

Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes Research Paper

Salvador Alonso, Meng Su, Jace W. Jones, Sudipto Ganguly, Maureen A. Kane, Richard J. Jones, Gabriel Ghiaur

Published Apr 10, 2015 · Vol. 6, No. 17 · pp. 14905-14912

Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER) Research Paper

Shao Ma, Ning Yin, Xiaomei Qi, Sandra L. Pfister, Mei-Jie Zhang, Rong Ma, Guan Chen

Published Apr 10, 2015 · Vol. 6, No. 15 · pp. 13320-13333

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1Î± accumulation in both endothelial and tumor cells Research Paper

Yan Wang, Jia-Xin Li, Ying-Qing Wang, Ze-Hong Miao

Published Apr 10, 2015 · Vol. 6, No. 18 · pp. 16031-16042

A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer Research Paper

Vladimir Lazar, Eitan Rubin, Stephane Depil, Yudi Pawitan, Jean-FranÃ§ois Martini, Jesus Gomez-Navarro, Antoine Yver, Zhengyin Kan, Jonathan R. Dry, Jeanne Kehren, Pierre Validire, Jordi Rodon, Philippe Vielh, Michel Ducreux, Susan Galbraith, Manfred Lehnert, Amir Onn, Raanan Berger, Marco A. Pierotti, Angel Porgador, CS Pramesh, Ding-wei Ye, Andre L. Carvalho, Gerald Batist, Thierry Le Chevalier, Philippe Morice, Benjamin Besse, Gilles Vassal, Andrew Mortlock, Johan Hansson, Ioana Berindan-Neagoe, Robert Dann, Joel Haspel, Alexandru Irimie A, Steve Laderman, Hovav Nechushtan, Amal S. Al Omari, Trent Haywood, Catherine Bresson, Khee Chee Soo, Gary Palmer, Ludovic Lacroix, Serge Koscielny, Karina Agda Eterovic, Jean-Yves Blay, Richard Buller, Alexander Eggermont, Richard L. Schilsky, John Mendelsohn, Jean-Charles Soria, Mace Rothenberg, Jean-Yves Scoazec, Waun Ki Hong, Razelle Kurzrock

Published Apr 3, 2015 · Vol. 6, No. 16 · pp. 14139-14152

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia Research Paper

AndrÃ© Bortolini Silveira, Angelo Brunelli Albertoni Laranjeira, Gisele Olinto Libanio Rodrigues, Rodrigues Leal, Bruno AntÃ³nio Cardoso, JoÃ£o Taborda Barata, Rosendo Augusto Yunes, Nilson Ivo Tonin Zanchin, SÃlvia Regina Brandalise, JosÃ© AndrÃ©s Yunes

Published Apr 1, 2015 · Vol. 6, No. 15 · pp. 13105-13118

Anti-β₂-microglobulin monoclonal antibodies overcome bortezomib resistance in multiple myeloma by inhibiting autophagy Research Paper

Mingjun Zhang, Jin He, Zhiqiang Liu, Yong Lu, Yuhuan Zheng, Haiyan Li, Jingda Xu, Huan Liu, Jianfei Qian, Robert Z. Orlowski, Larry W. Kwak, Qing Yi, Jing Yang

Published Mar 31, 2015 · Vol. 6, No. 11 · pp. 8567-8578

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancer Research Paper

Erratum: Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms Errata

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer Research Paper

Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer Priority Research Paper

Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells Priority Research Paper

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

Epithelial to mesenchymal transition is associated with rapamycin resistance Research Paper

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression Research Paper

Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort Clinical Research Papers

FGF23 is elevated in multiple myeloma and increases heparanase expression by tumor cells Research Paper

Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma Research Paper

MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma Research Paper

NHE9 induces chemoradiotherapy resistance in esophageal squamous cell carcinoma by upregulating the Src/Akt/Î²-catenin pathway and Bcl-2 expression Research Paper

Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes Research Paper

Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER) Research Paper

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1Î± accumulation in both endothelial and tumor cells Research Paper

A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer Research Paper

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia Research Paper

Anti-β₂-microglobulin monoclonal antibodies overcome bortezomib resistance in multiple myeloma by inhibiting autophagy Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancer Research Paper

Erratum: Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms Errata

Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporter Research Paper

Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer Research Paper

Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer Priority Research Paper

Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells Priority Research Paper

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

Epithelial to mesenchymal transition is associated with rapamycin resistance Research Paper

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression Research Paper

Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort Clinical Research Papers

FGF23 is elevated in multiple myeloma and increases heparanase expression by tumor cells Research Paper

Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma Research Paper

MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma Research Paper

NHE9 induces chemoradiotherapy resistance in esophageal squamous cell carcinoma by upregulating the Src/Akt/Î²-catenin pathway and Bcl-2 expression Research Paper

Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes Research Paper

Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER) Research Paper

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1Î± accumulation in both endothelial and tumor cells Research Paper

A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer Research Paper

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia Research Paper

Anti-β2-microglobulin monoclonal antibodies overcome bortezomib resistance in multiple myeloma by inhibiting autophagy Research Paper

Anti-β₂-microglobulin monoclonal antibodies overcome bortezomib resistance in multiple myeloma by inhibiting autophagy Research Paper