The Oncosearch | Oncotarget

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

He Wang, Henghui Yin, Fengjiao Yan, Mingna Sun, Lingran Du, Wei Peng, Qiuli Li, Yinghong Feng, Yi Zhou

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2827-2842

Advances in targeted therapies and new promising targets in esophageal cancer Review

Abbes Belkhiri, Wael El-Rifai

Published Dec 30, 2014 · Vol. 6, No. 3 · pp. 1348-1358

Keywords: adenocarcinoma, esophageal, gastric, cancer, targeted therapy

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Hui Zhang, Huanwen Wu, Jian Guan, Li Wang, Xinyu Ren, Xiaohua Shi, Zhiyong Liang, Tonghua Liu

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 3085-3097

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

Arjun Kalvala, Li Gao, Brittany Aguila, Tyler Reese, Gregory A. Otterson, Miguel A. Villalona-Calero, Wenrui Duan

Published Dec 30, 2014 · Vol. 6, No. 11 · pp. 8777-8787

miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPÎ² Research Paper

Xiao-Fei Zhang, Ke-ke Li, Lu Gao, Shang-Ze Li, Ke Chen, Jun-Bin Zhang, Di Wang, Rong-Fu Tu, Jin-Xiang Zhang, Kai-Xiong Tao, Guobin Wang, Xiao-Dong Zhang

Published Dec 27, 2014 · Vol. 6, No. 6 · pp. 4144-4158

Keywords: microRNA-191, colorectal cancer, apoptosis, C/EBPÎ², tumorigenesis.

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma Research Paper

Mohamed A.Y. Abdel Malek, Sajjeev Jagannathan, Ehsan Malek, Douaa M. Sayed, Sahar A. Elgammal, Hanan G. Abd El-Azeem, Nabila M. Thabet, James J. Driscoll

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3098-3110

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Alexander J. Lakhter, James Hamilton, Pierre C. Dagher, Suresh Mukkamala, Takashi Hato, X. Charlie Dong, Lindsey D. Mayo, Robert A. Harris, Anantha Shekhar, Mircea Ivan, Nickolay Brustovetsky, Samisubbu R. Naidu

Published Dec 26, 2014 · Vol. 5, No. 24 · pp. 12694-12703

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

Youhong Liu, Lin Chen, Zhicheng Gong, Liangfang Shen, Chinghai Kao, Janet M. Hock, Lunquan Sun, Xiong Li

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3055-3070

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

Duane H. Hamilton, Romaine I. Fernando, Jeffrey Schlom, Claudia Palena

Published Dec 26, 2014 · Vol. 6, No. 7 · pp. 4853-4862

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Wafa Hassen, Alboukadel Kassambara, Thierry Reme, Surinder Sahota, Anja Seckinger, Laure Vincent, Guillaume Cartron, JÃ©rÃ´me Moreaux, Dirk Hose, Bernard Klein

Published Dec 26, 2014 · Vol. 6, No. 8 · pp. 6431-6447

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

Barbie Taylor-Harding, Paul-Joseph Aspuria, Hasmik Agadjanian, Dong-Joo Cheon, Takako Mizuno, Danielle Greenberg, Jenieke R. Allen, Lindsay Spurka, Vincent Funari, Elizabeth Spiteri, Qiang Wang, Sandra Orsulic, Christine Walsh, Beth Y. Karlan, Ruprecht W. Wiedemeyer

Published Dec 22, 2014 · Vol. 6, No. 2 · pp. 696-714

Keywords: Cyclin-dependent kinase inhibitors, palbociclib, dinaciclib, Cyclin E1, ovarian cancer

Mastl kinase, a promising therapeutic target, promotes cancer recurrence Research Paper

Ling Wang, Vivian Q. Luong, Peter J. Giannini, Aimin Peng

Published Dec 22, 2014 · Vol. 5, No. 22 · pp. 11479-11489

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

Valentina Fogal, Ivan Babic, Ying Chao, Sandra Pastorino, Rajesh Mukthavaram, Pengfei Jiang, Yoon-Jae Cho, Sandeep C. Pingle, John R. Crawford, David E. Piccioni, Santosh Kesari

Published Dec 22, 2014 · Vol. 6, No. 2 · pp. 1157-1170

Keywords: mitochondrial p32, c-Myc, glutamine addiction, brain cancer

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa

Published Dec 19, 2014 · Vol. 5, No. 23 · pp. 11847-11856

Keywords: colorectal cancer, heregulin, resistance, cetuximab, patritumab

Critical role of NF-κB in pancreatic cancer Review

Lakshmi Prabhu, Rasika Mundade, Murray Korc, Patrick J. Loehrer, Tao Lu

Published Dec 19, 2014 · Vol. 5, No. 22 · pp. 10969-10975

Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors Research Paper

Zeyou Wang, Jing Yang, Gang Xu, Wei Wang, Changhong Liu, Honghui Yang, Zhibin Yu, Qianqian Lei, Lan Xiao, Jing Xiong, Liang Zeng, Juanjuan Xiang, Jian Ma, Guiyuan Li, Minghua Wu

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3147-3164

Cyclin alterations in diverse cancers: Outcome and co-amplification network Research Paper

Maria Schwaederle, Gregory A. Daniels, David E. Piccioni, Paul T. Fanta, Richard B. Schwab, Kelly A. Shimabukuro, Barbara A. Parker, Razelle Kurzrock

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3033-3042

MiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cells Research Paper

Qingling Yang, Yangyang Wang, Xiaohui Lu, Zunlan Zhao, Lihua Zhu, Sulian Chen, Qiong Wu, Changjie Chen, Zhiwei Wang

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3268-3279

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Yu Fujita, Shigehiro Yagishita, Fumitaka Takeshita, Yusuke Yamamoto, Kazuyoshi Kuwano, Takahiro Ochiya

Published Dec 17, 2014 · Vol. 6, No. 5 · pp. 3335-3345

Keywords: RPN2, NSCLC, RNAi, siRNA, malignancy

Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells Priority Research Paper

Franziska Schmidt, Meike Kunze, Ann-Christine Loock, Matthias Dobbelstein

Published Dec 15, 2014 · Vol. 6, No. 2 · pp. 617-632

Keywords: DNA damage, cisplatin, gemcitabine, siRNA screen, ubiquitin ligase, G2E3, Chk1

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

Advances in targeted therapies and new promising targets in esophageal cancer Review

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPÎ² Research Paper

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma Research Paper

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

Mastl kinase, a promising therapeutic target, promotes cancer recurrence Research Paper

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Critical role of NF-κB in pancreatic cancer Review

Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors Research Paper

Cyclin alterations in diverse cancers: Outcome and co-amplification network Research Paper

MiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cells Research Paper

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

Advances in targeted therapies and new promising targets in esophageal cancer Review

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Overexpression of Rad51C splice variants in colorectal tumors Research Paper

miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPÎ² Research Paper

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma Research Paper

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells Research Paper

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Clinical Research Papers

Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS Research Paper

Mastl kinase, a promising therapeutic target, promotes cancer recurrence Research Paper

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Critical role of NF-κB in pancreatic cancer Review

Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors Research Paper

Cyclin alterations in diverse cancers: Outcome and co-amplification network Research Paper

MiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cells Research Paper

Prognostic and therapeutic impact of RPN2-mediated tumor malignancy in non-small-cell lung cancer Research Paper

Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells Priority Research Paper