The Oncosearch | Oncotarget

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Radhika R. Gudi, Harinarayanan Janakiraman, Philip H. Howe, Viswanathan Palanisamy, Chenthamarakshan Vasu

Published Mar 27, 2021 · Vol. 12, No. 8 · pp. 807-822

Keywords: tumorigenesis, epithelial-mesenchymal transition, oral squamous cell carcinoma, EGFR, CPAP

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Chandni Desai, Jon Thomason, Jordan L. Kohlmeyer, Anna C. Reisetter, Parmanand Ahirwar, Khadijeh Jahanseir, Mariah Leidinger, Georgina Ofori-Amanfo, Karen Fritchie, Sadanandan E. Velu, Patrick Breheny, Dawn E. Quelle, Munir R. Tanas

Published Mar 21, 2021 · Vol. 12, No. 8 · pp. 740-755

Keywords: sarcoma, YAP, TAZ, p53-MDM2, RABL6A

[¹⁸F]FDG and [¹⁸F]FES positron emission tomography for disease monitoring and assessment of anti-hormonal treatment eligibility in granulosa cell tumors of the ovary Research Paper

Joline F. Roze, Hannah S. van Meurs, Glen R. Monroe, Wouter B. Veldhuis, Luc R.C.W. van Lonkhuijzen, Roel J. Bennink, Jolijn W. Groeneweg, Petronella O. Witteveen, Geertruida N. Jonges, Ronald P. Zweemer, Arthur J.A.T. Braat

Published Mar 19, 2021 · Vol. 12, No. 7 · pp. 665-673

Keywords: positron emission tomography (PET), 18F-fluoroestradiol (¹⁸F-FES), 18F-fluoro-deoxyglucose (¹⁸F-FDG), granulosa cell tumors (GCTs), hormone receptors

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Brittany Mull, Ryan Davis, Iqbal Munir, Mia C. Perez, Alfred A. Simental, Salma Khan

Published Mar 12, 2021 · Vol. 12, No. 7 · pp. 596-607

Keywords: DBP, thyroid cancer, health disparities

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Jared A. Sninsky, Kumar S. Bishnupuri, Iván González, Nikolaos A. Trikalinos, Ling Chen, Brian K. Dieckgraefe

Published Feb 8, 2021 · Vol. 12, No. 4 · pp. 278-291

Keywords: Reg4, CD44, CD44ICD, colorectal cancer

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

Leonardo G. da Fonseca, Carla Fuster-Anglada, Cristina Carrera, Cristina Millán, Esther Samper, Victor Sapena, Álvaro Díaz-González, Marco Sanduzzi-Zamparelli, Cassia Leal, Alejandro Forner, Jordi Bruix, Maria Reig, Loreto Boix, Alba Díaz

Published Feb 5, 2021 · Vol. 12, No. 5 · pp. 440-449

Keywords: hepatocellular carcinoma, tyrosine kinase inhibitors, treatment adverse events, skin lesions, molecular profiling

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Uri Rozovski, David M. Harris, Ping Li, Zhiming Liu, Preetesh Jain, Taghi Manshouri, Ivo Veletic, Alessandra Ferrajoli, Prithviraj Bose, Phillip Thompson, Nitin Jain, Srdan Verstovsek, William Wierda, Michael J. Keating, Zeev Estrov

Published Jan 30, 2021 · Vol. 12, No. 5 · pp. 401-411

Keywords: CLL, STAT3, GLI1, apoptosis, transcription

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Gerrit Spanier, Daniela Weidt, Dirk Hellwig, Johannes K.H. Meier, Torsten E. Reichert, Jirka Grosse

Published Dec 22, 2020 · Vol. 12, No. 1 · pp. 37-48

Keywords: FDG PET/CT, TLG, MTV, oral squamous cell carcinoma, prognostic value

Toward radiomics for assessment of response to systemic therapies in lung cancer Research Perspective

Shawn Sun, Florent L. Besson, Binsheng Zhao, Lawrence H. Schwartz, Laurent Dercle

Published Dec 13, 2020 · Vol. 11, No. 51 · pp. 4677-4680

Keywords: positron emission tomography, computed tomography, prognosis, lung cancer, immunotherapy

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Katarina Reis, Jack L. Arbiser, Anders Hjerpe, Katalin Dobra, Pontus Aspenström

Published Dec 4, 2020 · Vol. 11, No. 50 · pp. 4637-4647

Keywords: malignant mesothelioma, actin dynamics, vimentin, cytoskeleton, imipramine blue

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Ahmad A. Nazem, Jacob Ruzevick, Manuel J. Ferreira Jr

Published Dec 2, 2020 · Vol. 11, No. 49 · pp. 4544-4553

Keywords: meningioma, skull base, NGS, sequencing, biomarker

Inorganic polyphosphate as an energy source in tumorigenesis Research Paper

Jerusha Boyineni, Simone T. Sredni, Naira V. Margaryan, Lusine Demirkhanyan, Michael Tye, Robert Johnson, Fernando Gonzalez-Nilo, Mary J.C. Hendrix, Evgeny Pavlov, Marcelo B. Soares, Eleonora Zakharian, Sergey Malchenko

Published Nov 28, 2020 · Vol. 11, No. 50 · pp. 4613-4624

Keywords: polyphosphate, energy source, OXPHOS, glycolysis, metabolism

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

Dileep Kumar M. Guruswamy, Kyathegowdana Doddi Srivinavasa Balaji, Kattepura Krishnappa Dharmappa, Shankar Jayarama

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4661-4676

Keywords: novel chalcone, Bcl2, caspase 3, BAX, receptor tyrosine kinase inhibitor

Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells Research Paper

Madhav Sankunny, Charis Eng

Published Nov 25, 2020 · Vol. 11, No. 50 · pp. 4625-4636

Keywords: KLLN, nuclear export, NES, proteasomal degradation

Treatment of elderly patients with refractory/relapsed multiple myeloma: oral drugs adherence and the COVID-19 outbreak Research Perspective

Flávia Dias Xavier, Fernando Sergio Blumm Ferreira, Rodrigo Martins Abreu

Published Nov 10, 2020 · Vol. 11, No. 47 · pp. 4371-4386

Keywords: healthcare, multiple myeloma, adherence, elderly, refractory/relapsed

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Vânia Gonçalves, Andreia F.A. Henriques, Paulo Matos, Peter Jordan

Published Nov 9, 2020 · Vol. 11, No. 47 · pp. 4421-4437

Keywords: ibuprofen, protein kinase, RAC1B, alternative splicing, colorectal cancer cells

Association between vitamin D and ovarian cancer development in BRCA1 mutation carriers Research Paper

Tanja Pejovic, Sonali Joshi, Shawn Campbell, Sarah Thisted, Fuhua Xu, Jing Xu

Published Nov 4, 2020 · Vol. 11, No. 45 · pp. 4104-4114

Keywords: epithelial ovarian cancer, BRCA1 mutation carriers, vitamin D, cancer prevention

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas Research Paper

Geraldine O'Sullivan Coyne, Shivaani Kummar, Robert S. Meehan, Khanh Do, Jerry M. Collins, Larry Anderson, Kazusa Ishii, Naoko Takebe, Jennifer Zlott, Lamin Juwara, Richard Piekarz, Howard Streicher, Elad Sharon, Larry Rubinstein, Andrea Regier Voth, Jay Lozier, Angie B. Dull, Deborah Wilsker, Toshinori Hinoue, Peter W. Laird, Katherine V. Ferry-Galow, Robert J. Kinders, Ralph E. Parchment, James H. Doroshow, Alice P. Chen

Published Oct 12, 2020 · Vol. 11, No. 44 · pp. 3959-3971

Keywords: DNA damage repair, base excision repair, MGMT, rational combination therapy, molecular pharmacodynamics

Regulation of breast cancer oncogenesis by the cell of origin’s differentiation state Research Paper

Sarah C. Petrova, Ihsaan Ahmad, Christine Nguyen, Stuart D. Ferrell Jr, Sabrina R. Wilhelm, Yin Ye, Sanford H. Barsky

Published Oct 10, 2020 · Vol. 11, No. 43 · pp. 3832-3848

Keywords: transgenic mice, induced pluripotent stem cells (iPSCs), breast oncogenesis, differentiation

Correction: Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma Correction

Ke Hu, Savalan Babapoor-Farrokhran, Murilo Rodrigues, Monika Deshpande, Brooks Puchner, Fabiana Kashiwabuchi, Syed Junaid Hassan, Laura Asnaghi, James T. Handa, Shannath Merbs, Charles G. Eberhart, Gregg L. Semenza, Silvia Montaner, Akrit Sodhi

Published Oct 9, 2020 · Vol. 12, No. 5 · pp. 519-520

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Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

[¹⁸F]FDG and [¹⁸F]FES positron emission tomography for disease monitoring and assessment of anti-hormonal treatment eligibility in granulosa cell tumors of the ovary Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Toward radiomics for assessment of response to systemic therapies in lung cancer Research Perspective

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Inorganic polyphosphate as an energy source in tumorigenesis Research Paper

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells Research Paper

Treatment of elderly patients with refractory/relapsed multiple myeloma: oral drugs adherence and the COVID-19 outbreak Research Perspective

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Association between vitamin D and ovarian cancer development in BRCA1 mutation carriers Research Paper

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas Research Paper

Regulation of breast cancer oncogenesis by the cell of origin’s differentiation state Research Paper

Correction: Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

[18F]FDG and [18F]FES positron emission tomography for disease monitoring and assessment of anti-hormonal treatment eligibility in granulosa cell tumors of the ovary Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Mutational profile of skin lesions in hepatocellular carcinoma patients under tyrosine kinase inhibition: a repercussion of a wide-spectrum activity Research Paper

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Toward radiomics for assessment of response to systemic therapies in lung cancer Research Perspective

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Inorganic polyphosphate as an energy source in tumorigenesis Research Paper

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells Research Paper

Treatment of elderly patients with refractory/relapsed multiple myeloma: oral drugs adherence and the COVID-19 outbreak Research Perspective

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Association between vitamin D and ovarian cancer development in BRCA1 mutation carriers Research Paper

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas Research Paper

Regulation of breast cancer oncogenesis by the cell of origin’s differentiation state Research Paper

Correction: Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma Correction

[¹⁸F]FDG and [¹⁸F]FES positron emission tomography for disease monitoring and assessment of anti-hormonal treatment eligibility in granulosa cell tumors of the ovary Research Paper