The Oncosearch | Oncotarget

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Dong Hyun Jo, Jin Hyoung Kim, Chang Sik Cho, Young-Lai Cho, Hyoung Oh Jun, Young Suk Yu, Jeong-Ki Min, Jeong Hun Kim

Published Nov 3, 2014 · Vol. 5, No. 22 · pp. 11513-11525

Keywords: Retinoblastoma, STAT3 transcription factor, miR-17-92

Regulation of ERBB3/HER3 signaling in cancer Review

Kalpana Mujoo, Byung-Kwon Choi, Zhao Huang, Ningyan Zhang, Zhiqiang An

Published Nov 2, 2014 · Vol. 5, No. 21 · pp. 10222-10236

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status Research Paper

Zhiguang Xiao, Bianca Sperl, Axel Ullrich, Pjotr Knyazev

Published Nov 2, 2014 · Vol. 5, No. 24 · pp. 12877-12890

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support Research Paper

Jeannette Boutter, Yun Huang, Blerim Marovca, Andreas Vonderheit, Michael A. Grotzer, Cornelia Eckert, Gunnar Cario, Bernd Wollscheid, Peter Horvath, Beat C. Bornhauser, Jean-Pierre Bourquin

Published Nov 1, 2014 · Vol. 5, No. 22 · pp. 11501-11512

Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases Clinical Research Papers

Zoran Gatalica, Sherri Z. Millis, Semir Vranic, Ryan Bender, Gargi D. Basu, Andreas Voss, Daniel D. Von Hoff

Published Oct 31, 2014 · Vol. 5, No. 23 · pp. 12440-12447

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

Catherine E. Waters, Joshua C. Saldivar, Zaynab A. Amin, Morgan S. Schrock, Kay Huebner

Published Oct 31, 2014 · Vol. 6, No. 5 · pp. 3409-3419

Keywords: FHIT, replication stress, DNA double strand breaks, APOBEC deaminase, mutations

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis Research Paper

Ritesh K. Srivastava, Samer Zaid Kaylani, Nayf Edrees, Changzhao Li, Sarang S. Talwelkar, Jianmin Xu, Komaraiah Palle, Joseph G. Pressey, Mohammad Athar

Published Oct 31, 2014 · Vol. 5, No. 23 · pp. 12151-12165

RNA-seq analysis reveals significant effects of EGFR signalling on the secretome of mesenchymal stem cells Research Paper

Antonella De Luca, Cristin Roma, Marianna Gallo, Francesca Fenizia, Francesca Bergantino, Daniela Frezzetti, Susan Costantini, Nicola Normanno

Published Oct 29, 2014 · Vol. 5, No. 21 · pp. 10518-10528

The novel IÎºB kinase Î² inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma Research Paper

Yukiyo Tada, Shoichiro Kokabu, Goro Sugiyama, Chihiro Nakatomi, Kazuhiro Aoki, Hidefumi Fukushima, Kenji Osawa, Yasutaka Sugamori, Keiichi Ohya, Masato Okamoto, Tomoyuki Fujikawa, Akiko Itai, Kou Matsuo, Seiji Watanabe, Eijiro Jimi

Published Oct 28, 2014 · Vol. 5, No. 23 · pp. 12317-12330

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression Priority Research Paper

Claudia A. Benavente, David Finkelstein, Dianna A. Johnson, Jean-Christophe Marine, Ruth Ashery-Padan, Michael A. Dyer

Published Oct 28, 2014 · Vol. 5, No. 20 · pp. 9594-9608

Keywords: Rb, E2F, HELLS, UHRF1, retinoblastoma, cancer

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia Research Paper

Houda Alachkar, Martin B.G. Mutonga, Klaus H. Metzeler, Noreen Fulton, Gregory Malnassy, Tobias Herold, Karsten Spiekermann, Stefan K. Bohlander, Wolfgang Hiddemann, Yo Matsuo, Wendy Stock, Yusuke Nakamura

Published Oct 28, 2014 · Vol. 5, No. 23 · pp. 12371-12382

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma Research Paper

Rosaria ChilÃ, Alessandra Basana, Monica Lupi, Federica Guffanti, Eugenio Gaudio, Andrea Rinaldi, Luciano Cascione, Valentina Restelli, Chiara Tarantelli, Francesco Bertoni, Giovanna Damia, Laura Carrassa

Published Oct 25, 2014 · Vol. 6, No. 5 · pp. 3394-3408

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets Research Paper

Costa Frangou, Ying-Wei Li, He Shen, Nuo Yang, Kayla E. Wilson, Maxime Blijlevens, Jin Guo, Norma J. Nowak, Jianmin Zhang

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12166-12176

Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance Research Paper

Chien-Feng Li, Fu-Min Fang, Hsing-Jien Kung, Li-Tzong Chen, Jun-Wen Wang, Jen-Wei Tsai, Shih Chen Yu, Yu-Hui Wang, Shau-Hsuan Li, Hsuan-Ying Huang

Published Oct 24, 2014 · Vol. 5, No. 22 · pp. 11428-11441

A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression Research Paper

Alessandro Poli, Giulia Ramazzotti, Alessandro Matteucci, Lucia Manzoli, Annalisa Lonetti, Pann-Ghill Suh, James A. McCubrey, Lucio Cocco

Published Oct 24, 2014 · Vol. 5, No. 22 · pp. 11526-11540

Keywords: PKC, Cyclin, Cell Cycle, PLC, DAG, nuclei

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas Research Paper

Mi-Young Cho, Jae Youn Cheong, Wonchung Lim, Sujin Jo, Youngsoo Lee, Hee-Jung Wang, Kyou-Hoon Han, Hyeseong Cho

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12233-12246

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer Research Paper

Julia Femel, Elisabeth J.M. Huijbers, Falk Saupe, Jessica Cedervall, Lei Zhang, Pernilla Roswall, Erik Larsson, Helena Olofsson, Kristian Pietras, Anna Dimberg, Lars Hellman, Anna-Karin Olsson

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12418-12427

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/Î²-catenin pathway Research Paper

Tsai-Hsien Hung, Sheng-Chi Hsu, Ching-Yi Cheng, Kong-Bung Choo, Ching-Ping Tseng, Tse-Ching Chen, Ying-Wei Lan, Tsung-Teng Huang, Hsin-Chih Lai, Chuan-Mu Chen, Kowit-Yu Chong

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12273-12290

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis Research Paper

Carmine Carbone, Geny Piro, Matteo Fassan, Anna Tamburrino, Maria Mihaela Mina, Marco Zanotto, Paul J. Chiao, Claudio Bassi, Aldo Scarpa, Giampaolo Tortora, Davide Melisi

Published Oct 24, 2014 · Vol. 6, No. 15 · pp. 13822-13834

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

David S. Hong, Razelle Kurzrock, Marilyn Mulay, Erik Rasmussen, Benjamin M. Wu, Michael B. Bass, Zhandong D. Zhong, Greg Friberg, Lee S. Rosen

Published Oct 23, 2014 · Vol. 5, No. 22 · pp. 11154-11167

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Regulation of ERBB3/HER3 signaling in cancer Review

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status Research Paper

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support Research Paper

Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases Clinical Research Papers

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis Research Paper

RNA-seq analysis reveals significant effects of EGFR signalling on the secretome of mesenchymal stem cells Research Paper

The novel IÎºB kinase Î² inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma Research Paper

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression Priority Research Paper

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia Research Paper

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma Research Paper

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets Research Paper

Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance Research Paper

A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression Research Paper

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas Research Paper

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer Research Paper

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/Î²-catenin pathway Research Paper

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Regulation of ERBB3/HER3 signaling in cancer Review

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status Research Paper

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support Research Paper

Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases Clinical Research Papers

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis Research Paper

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis Research Paper

RNA-seq analysis reveals significant effects of EGFR signalling on the secretome of mesenchymal stem cells Research Paper

The novel IÎºB kinase Î² inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma Research Paper

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression Priority Research Paper

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia Research Paper

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma Research Paper

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets Research Paper

Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance Research Paper

A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression Research Paper

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas Research Paper

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer Research Paper

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/Î²-catenin pathway Research Paper

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers