The Oncosearch | Oncotarget

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 Research Paper

Rui Liu, Shan Huang, Yunlong Lei, Tao Zhang, Kui Wang, Bo Liu, Edouard C. Nice, Rong Xiang, Ke Xie, Jingyi Li, Canhua Huang

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 935-952

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

Hongxin Ma, Xuetian Yue, Lifen Gao, Xiaohong Liang, Wenjiang Yan, Zhenyu Zhang, Haixia Shan, Hualin Zhang, Brett T. Spear, Chunhong Ma

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1049-1063

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

Huanzhang Hu, Yinghe Qiu, Minggao Guo, Yao Huang, Lin Fang, Zhangxiao Peng, Weidan Ji, Yang Xu, Shuwen Shen, Yan Yan, Xuandong Huang, Junnian Zheng, Changqing Su

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1079-1089

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Itay Pickholtz, Shira Saadyan, Gilmor I. Keshet, Victor S. Wang, Rachel Cohen, Peter Bouwman, Jos Jonkers, Stephen W. Byers, Moshe Z. Papa, Ronit I. Yarden

Published Nov 26, 2014 · Vol. 5, No. 23 · pp. 11827-11846

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity Priority Research Paper

Itsuhiro Takizawa, Mitchell G. Lawrence, Preetika Balanathan, Richard Rebello, Helen B. Pearson, Elika Garg, John Pedersen, Normand Pouliot, Robert Nadon, Matthew J. Watt, Renea A. Taylor, Patrick Humbert, Ivan Topisirovic, Ola Larsson, Gail P. Risbridger, Luc Furic

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 604-616

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

Matthias Scheffler, Marc Bos, Masyar Gardizi, Katharina KÃ¶nig, Sebastian Michels, Jana Fassunke, Carina Heydt, Helen KÃ¼nstlinger, Michaela Ihle, Frank Ueckeroth, Kerstin Albus, Monika Serke, Ulrich Gerigk, Wolfgang Schulte, Karin TÃ¶pelt, Lucia Nogova, Thomas Zander, Walburga Engel-Riedel, Erich Stoelben, Yon-Dschun Ko, Winfried Randerath, Britta Kaminsky, Jens Panse, Carolin Becker, Martin Hellmich, Sabine Merkelbach-Bruse, Lukas C. Heukamp, Reinhard BÃ¼ttner, JÃ¼rgen Wolf

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1315-1326

Aspartate Î²-hydroxylase expression promotes a malignant pancreatic cellular phenotype Research Paper

Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, Jack R. Wands

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1231-1248

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss Research Paper

Rafaela Andrade-Vieira, Donna Goguen, Heidi A. Bentley, Chris V. Bowen, Paola A. Marignani

Published Nov 25, 2014 · Vol. 5, No. 24 · pp. 12738-12752

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors Research Paper

Ming Xu, Changhong Zhu, Xian Zhao, Cheng Chen, Hailong Zhang, Haihua Yuan, Rong Deng, Jinzhuo Dou, Yanli Wang, Jian Huang, Qin Chen, Bin Jiang, Jianxiu Yu

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 979-994

A switch from CD44⁺ cell to EMT cell drives the metastasis of prostate cancer Research Paper

Zhiqun Shang, Qiliang Cai, Minghao Zhang, Shimiao Zhu, Yuan Ma, Libin Sun, Ning Jiang, Jing Tian, Xiaodan Niu, Jiatong Chen, Yinghao Sun, Yuanjie Niu

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 1202-1216

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Hon-Yi Lin, Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Tze-Ta Huang, Chih-En Tseng, Liang-Yu Shih, Ru-Inn Lin, Jora M.J. Lin, Yi-Hui Lai, Chia-Bin Chang, Feng-Chun Hsu, Liang-Cheng Chen, Shiang-Jiun Tsai, Yu-Chieh Su, Szu-Chi Li, Hung-Chih Lai, Wen-Lin Hsu, Dai-Wei Liu, Chien-Kuo Tai, Shu-Fen Wu, Michael W.Y. Chan

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 915-934

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Takuya Nakamura, Satoru Shinriki, Hirofumi Jono, Jianying Guo, Mitsuharu Ueda, Mitsuhiro Hayashi, Satoshi Yamashita, Andries Zijlstra, Hideki Nakayama, Akimitsu Hiraki, Masanori Shinohara, Yukio Ando

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 1008-1019

Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer Research Paper

Fengjin Zhao, Tianxin Lin, Wang He, Jinli Han, Dingjun Zhu, Kaishun Hu, Weicong Li, Zaosong Zheng, Jian Huang, Wenlian Xie

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 1064-1078

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

Galina Kochneva, Evgeniy Zonov, Antonina Grazhdantseva, Anastasiya Yunusova, Galina Sibolobova, Evgeniy Popov, Oleg Taranov, Sergei Netesov, Peter Chumakov, Elena Ryabchikova

Published Nov 19, 2014 · Vol. 5, No. 22 · pp. 11269-11282

JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells Research Paper

Shuhei Suzuki, Masashi Okada, Keita Shibuya, Manabu Seino, Atsushi Sato, Hiroyuki Takeda, Shizuka Seino, Takashi Yoshioka, Chifumi Kitanaka

Published Nov 19, 2014 · Vol. 6, No. 1 · pp. 458-470

Keywords: cancer initiating cells, chemotherapy, combination therapy, c-Jun N-terminal kinase

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer Research Paper

Anna Chen, Christina S.F. Wong, Mira C.P. Liu, Colin M. House, Jaclyn Sceneay, David D. Bowtell, Erik W. Thompson, Andreas MÃ¶ller

Published Nov 18, 2014 · Vol. 6, No. 2 · pp. 862-873

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Nian-Kang Sun, Shang-Lang Huang, Pu-Yuan Chang, Hsing-Pang Lu, Chuck C.-K. Chao

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 11939-11956

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation Priority Research Paper

Ulrike Keitel, Andreas Scheel, JÃ¼rgen Thomale, Rovena Halpape, Silke KaulfuÃŸ, Christina Scheel, Matthias Dobbelstein

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 11778-11791

Keywords: Bcl-xL, Chemo-resistance, Epithelial Mesenchymal Transition, Apoptosis, BH3-mimetic

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells Research Paper

Martin Puhr, Julia Hoefer, Hannes Neuwirt, Iris E. Eder, Johann Kern, Georg SchÃ¤fer, Stephan Geley, Isabel Heidegger, Helmut Klocker, Zoran Culig

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 12043-12056

Keywords: prostate cancer, PIAS1, docetaxel, chemotherapy resistance, apoptosis

Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells Research Paper

Takumi Shiraishi, James E. Verdone, Jessie Huang, Ulf D. Kahlert, James R. Hernandez, Gonzalo Torga, Jelani C. Zarif, Tamir Epstein, Robert Gatenby, Annemarie McCartney, Jennifer H. Elisseeff, Steven M. Mooney, Steven S. An, Kenneth J. Pienta

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 130-143

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 Research Paper

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity Priority Research Paper

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

Aspartate Î²-hydroxylase expression promotes a malignant pancreatic cellular phenotype Research Paper

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss Research Paper

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors Research Paper

A switch from CD44⁺ cell to EMT cell drives the metastasis of prostate cancer Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer Research Paper

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells Research Paper

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation Priority Research Paper

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells Research Paper

Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 Research Paper

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

Targeted Hsp70 expression combined with CIK-activated immune reconstruction synergistically exerts antitumor efficacy in patient-derived hepatocellular carcinoma xenograft mouse models Research Paper

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and for growth inhibition of breast cancer cells and cancer stem-like cells. Research Paper

Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity Priority Research Paper

PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies Clinical Research Papers

Aspartate Î²-hydroxylase expression promotes a malignant pancreatic cellular phenotype Research Paper

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss Research Paper

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors Research Paper

A switch from CD44+ cell to EMT cell drives the metastasis of prostate cancer Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Intrinsic TGF-Î²2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells Research Paper

Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer Research Paper

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression Research Paper

JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells Research Paper

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation Priority Research Paper

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells Research Paper

Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells Research Paper

A switch from CD44⁺ cell to EMT cell drives the metastasis of prostate cancer Research Paper