The Oncosearch | Oncotarget

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Powrnima Joshi, Barbara Jacobs, Adeeb Derakhshan, Lee R. Moore, Paul Elson, Pierre L. Triozzi, Ernest Borden, Maciej Zborowski

Published Feb 3, 2014 · Vol. 5, No. 9 · pp. 2450-2461

Keywords: circulating melanoma cells, CTC, Melan-A, S100B, magnetic separation, negative selection

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Patrick J. Killela, Christopher J. Pirozzi, Patrick Healy, Zachary J. Reitman, Eric Lipp, Ahmed B. Rasheed, Rui Yang, Bill H. Diplas, Zhaohui Wang, Paula K. Greer, Huishan Zhu, Catherine Y. Wang, Austin B. Carpenter, Henry Friedman, Allan H. Friedman, Stephen T. Keir, Jie He, Yiping He, Roger E. McLendon, James E. Herndon II, Hai Yan, Darell D. Bigner

Published Jan 28, 2014 · Vol. 5, No. 6 · pp. 1515-1525

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Dimcho Bachvarov

Published Jan 27, 2014 · Vol. 5, No. 2 · pp. 544-560

Keywords: GALNT3, epithelial ovarian cancer, DNA hypomethylation, progression-free survival, microarrays, mucin O-glycosylation

Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication Research Paper

Tobias Forster, Vanessa Rausch, Yiyao Zhang, Orkhan Isayev, Katharina Heilmann, Frank Schoensiegel, Li Liu, Michelle Nessling, Karsten Richter, Sabrina Labsch, Clifford C. Nwaeburu, Juergen Mattern, Jury Gladkich, Nathalia Giese, Jens Werner, Peter Schemmer, Wolfgang Gross, Martha M. Gebhard, Clarissa Gerhauser, Michael Schaefer, Ingrid Herr

Published Jan 22, 2014 · Vol. 5, No. 6 · pp. 1621-1634

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Adrienne L. Watson, Bryant J. Keller, Kyle A. Williams, Namrata N. Damle, Samuel J. Finnerty, Leah K. Anderson, Andrew D. Greeley, Vincent W. Keng, Eric P. Rahrmann, Amanda L. Halfond, Natasha M. Powell, Margaret H. Collins, Tilat Rizvi, Christopher L. Moertel, Nancy Ratner, David A. Largaespada

Published Jan 20, 2014 · Vol. 5, No. 6 · pp. 1502-1514

Keywords: Malignant peripheral nerve sheath tumors, plexiform neurofibromas, Schwann cells, neurofibromatosis type 1 syndrome, neurofibromin 1, PI3K/AKT/mTOR signaling, MAPK signaling, targeted therapies, genetically engineered mouse models, combination therapy

Poly (ADP-ribose) polymerase 1 transcriptional regulation: A novel crosstalk between histone modification H3K9ac and ETS1 motif hypomethylation in BRCA1-mutated ovarian cancer Research Paper

Da Li, Fang-Fang Bi, Ji-Min Cao, Chen Cao, Chun-Yan Li, Bo Liu, Qing Yang

Published Dec 29, 2013 · Vol. 5, No. 1 · pp. 291-297

Keywords: PARP1, H3K9ac, ETS1, BRCA1, Ovarian cancer

CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus Research Paper

Andrew J. Murphy, Janene Pierce, Christian de Caestecker, Gregory D. Ayers, Alex Zhao, Jonathan R. Krebs, Vincente Kenyi Saito-Diaz, Ethan Lee, Alan O. Perantoni, Mark P. de Caestecker, Harold N. Lovvorn, III

Published Dec 28, 2013 · Vol. 5, No. 2 · pp. 386-402

Keywords: CITED1, Wilms tumor, WNT, WiT49, cancer stem cell

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Hendrik Ungefroren, Susanne Sebens, Klaudia Giehl, Ole Helm, Stephanie Groth, Fred Faendrich, Christoph Roecken, Bence Sipos, Hendrik Lehnert, Frank Gieseler

Published Dec 23, 2013 · Vol. 5, No. 1 · pp. 277-290

Keywords: Rac1b, Rac1, Smad, TGF-beta1, pancreatic ductal adenocarcinoma, cell migration

AID-induced remodeling of immunoglobulin genes and B cell fate Review

Brice Laffleur, Nicolas Denis-Lagache, Sophie PÃ©ron, Christophe Sirac, Jeanne Moreau, Michel CognÃ©

Published Dec 14, 2013 · Vol. 5, No. 5 · pp. 1118-1131

Keywords: AID, B cell fate, BCR, immunoglobulin genes

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Lotte Hiddingh, Bakhos A. Tannous, Jian Teng, Bas Tops, Judith Jeuken, Esther Hulleman, Sandra H. Boots-Sprenger, W. Peter Vandertop, David P. Noske, Gertjan J.L. Kaspers, Pieter Wesseling, Thomas Wurdinger

Published Dec 7, 2013 · Vol. 5, No. 2 · pp. 363-374

Keywords: Temozolomide resistance, glioblastoma, EFEMP1, Î³-secretase, Notch, GSI

Glycogen synthase kinase-3Î² inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth Research Paper

Jan Kroon, Lars S. in 't Veld, Jeroen T. Buijs, Henry Cheung, Geertje van der Horst, Gabri van der Pluijm

Published Dec 5, 2013 · Vol. 5, No. 19 · pp. 8986-8994

Keywords: Cancer Stem Cells, GSK-3Î², Metastasis, Prostate Cancer, Wnt signaling

Targeting nucleocytoplasmic transport in cancer therapy Review

Richard Hill, Bastien Cautain, Nuria de Pedro, Wolfgang Link

Published Nov 24, 2013 · Vol. 5, No. 1 · pp. 11-28

Keywords: Tumor suppressors, Cancer, Anti-cancer therapy, Nuclear export, nuclear import

EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-ÎºB activity Research Paper

Jung-Min Choi, Sushil Devkota, Young Hoon Sung, Han-Woong Lee

Published Nov 17, 2013 · Vol. 4, No. 12 · pp. 2383-2396

Keywords: EI24, EMT, NF-ÎºB, tumor progression

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

Shahin Assefnia, Sivanesan Dakshanamurthy, Jaime M. Guidry Auvil, Constanze Hampel, Panos Z. Anastasiadis, Bhaskar Kallakury, Aykut Uren, David W. Foley, Milton L. Brown, Lawrence Shapiro, Michael Brenner, David Haigh, Stephen W. Byers

Published Nov 15, 2013 · Vol. 5, No. 6 · pp. 1458-1474

Keywords: cadherin-11, breast cancer, glioblastoma, small molecule inhibitor, rheumatoid arthritis, celecoxib

Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity Research Paper

Ling Yu, Shiqing Liu, Chun Zhang, Bo Zhang, Bruno M. Simoes, Rachel Eyre, Yi Liang, Huichao Yan, Zheng Wu, Weichun Guo, Robert B. Clarke

Published Nov 5, 2013 · Vol. 4, No. 12 · pp. 2326-2338

Keywords: osteosarcoma, stem cells, sarcospheres, telomerase

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Kaiming Xu, Lanfang Wang, Hui-Kuo G. Shu

Published Oct 31, 2013 · Vol. 5, No. 5 · pp. 1241-1252

Keywords: glioblastoma, brain tumor, tumorigenesis, cyclooxygenase-2, Id1

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

Anton George Henssen, Theresa Thor, Andrea Odersky, Lukas Heukamp, Nicolai El-Hindy, Anneleen Beckers, Frank Slpeleman, Kristina Althoff, Simon SchÃ¤fers, Alexander Schramm, Ulrich Sure, Gudrun Fleischhack, Angelika Eggert, Johannes Hubertus Schulte

Published Oct 27, 2013 · Vol. 4, No. 11 · pp. 2080-2095

Keywords: BET bromodomains, BRD4, MYC, JQ1, pediatric brain tumors, targeted therapy

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

Kerstin Menck, Florian Klemm, Julia Christina Gross, Tobias Pukrop, Dirk Wenzel, Claudia Binder

Published Oct 21, 2013 · Vol. 4, No. 11 · pp. 2057-2066

Keywords: Breast cancer, exosomes, Evi, microvesicles, macrophages, Wnt 5a

14-3-3Ïƒ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells Research Paper

In-Kyu Kim, Sun-Mi Park, Hee Jun Cho, Kyoung Eun Baek, In-Koo Nam, Seung-Ho Park, Ki-Jun Ryu, Jinhyun Ryu, Jungil Choi, Soon-Chan Hong, Jae Won Kim, Chang Won Lee, Sang Soo Kang, Jiyun Yoo

Published Oct 19, 2013 · Vol. 4, No. 11 · pp. 2045-2056

Keywords: RhoGDI2, 14-3-3Ïƒ, gastric cancer, chemoresistance, metastasis

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Sabine Becker-Weimann, Gaofeng Xiong, Saori Furuta, Ju Han, Irene Kuhn, Uri-David Akavia, Dana Pe'er, Mina J. Bissell, Ren Xu

Published Oct 14, 2013 · Vol. 4, No. 11 · pp. 2010-2020

Keywords: disorganization gene signature, p65, RelB, three-dimensional tissue structure, tissue polarity

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Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Poly (ADP-ribose) polymerase 1 transcriptional regulation: A novel crosstalk between histone modification H3K9ac and ETS1 motif hypomethylation in BRCA1-mutated ovarian cancer Research Paper

CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

AID-induced remodeling of immunoglobulin genes and B cell fate Review

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Glycogen synthase kinase-3Î² inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth Research Paper

Targeting nucleocytoplasmic transport in cancer therapy Review

EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-ÎºB activity Research Paper

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

14-3-3Ïƒ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Poly (ADP-ribose) polymerase 1 transcriptional regulation: A novel crosstalk between histone modification H3K9ac and ETS1 motif hypomethylation in BRCA1-mutated ovarian cancer Research Paper

CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

AID-induced remodeling of immunoglobulin genes and B cell fate Review

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Glycogen synthase kinase-3Î² inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth Research Paper

Targeting nucleocytoplasmic transport in cancer therapy Review

EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-ÎºB activity Research Paper

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Research Paper

Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles Research Paper

14-3-3Ïƒ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper