The Oncosearch | Oncotarget

Pro-malignant properties of STAT3 during chronic inflammation Editorial Comments

Marco Demaria, Valeria Poli

Published Apr 20, 2012 · Vol. 3, No. 4 · pp. 359-360

Keywords: Stat3, cancer, inflammation, Hif-1alpha, aerobic glycolysis

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing Methodological Reports

Renee C. Tschumper, Yan W. Asmann, Asif Hossain, Paul M. Huddleston, Xiaosheng Wu, Angela Dispenzieri, Bruce W. Eckloff, Diane F. Jelinek

Published Apr 20, 2012 · Vol. 3, No. 4 · pp. 502-513

Keywords: IGHV, multiple myeloma, massively parallel sequencing

Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice Brief Reports

Carolina Vicente-DueÃ±as, Marcos Barajas-Diego, Isabel Romero-Camarero, Ines Gonzalez-Herrero, Teresa Flores, Isidro Sanchez-Garcia

Published Mar 8, 2012 · Vol. 3, No. 3 · pp. 261-266

Keywords: cancer, cancer stem cells (CSC), stem cells, mouse models, Telomerase inhibitors, drug discovery

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Roland H. Stauber, Shirley K. Knauer, Negusse Habtemichael, Carolin Bier, Britta Unruhe, Simona Weisheit, Stephanie Spange, Frank Nonnenmacher, Verena Fetz, Torsten Ginter, Sigrid Reichardt, Claus Liebmann, GÃ¼nter Schneider, Oliver H. KrÃ¤mer

Published Jan 28, 2012 · Vol. 3, No. 1 · pp. 31-43

Keywords: apoptosis, BH3-only protein, chemotherapy, hydroxyurea, oral cancer, therapy resistance, tumor xenograft, valproic acid

Regression of metastatic melanoma by targeting cancer stem cells Brief Reports

Max Schlaak, Patrick Schmidt, Christopher Bangard, Peter Kurschat, Cornelia Mauch, Hinrich Abken

Published Jan 28, 2012 · Vol. 3, No. 1 · pp. 22-30

Keywords: cancer stem cell, melanoma, CD20, rituximab

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target Review

Mourad Sanhaji, Claire T Friel, Linda Wordeman, Frank Louwen, Juping Yuan

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 935-947

Keywords: MCAK, mitotic kinases, chromosome instability, drug resistance, invasiveness

Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes Research Paper

Daniel J. Oâ€™Shannessy, Elizabeth B. Somers, Earl Albone, Xin Cheng, Young Chul Park, Brian E. Tomkowicz, Yoshitomo Hamuro, Thomas O. Kohl, Tracy M. Forsyth, Robert Smale, Yao-Shi Fu, Nicholas C. Nicolaides

Published Dec 27, 2011 · Vol. 2, No. 12 · pp. 1227-1243

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

Paula Vainio, Laura Lehtinen, Tuomas Mirtti, Mika Hilvo, Tuulikki SeppÃ¤nen-Laakso, Johannes Virtanen, Anna Sankila, Stig Nordling, Johan Lundin, Antti Rannikko, Matej OreÅ¡iÄ, Olli Kallioniemi, Kristiina Iljin

Published Dec 22, 2011 · Vol. 2, No. 12 · pp. 1176-1190

Keywords: Prostate cancer, PLA2G7, drug target, biomarker, statins

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy Research Perspective

Jean-Claude Chomel, Ali G. Turhan

Published Sep 22, 2011 · Vol. 2, No. 9 · pp. 713-727

Keywords: CML, tyrosine kinase inhibitors, leukemic stem cells, persistency, quiescence, undetectable molecular disease

Targeting mTOR for the treatment of AML. New agents and new directions. Research Perspective

Jessica K. Altman, Antonella Sassano, Leonidas C. Platanias

Published Jun 15, 2011 · Vol. 2, No. 6 · pp. 510-517

Keywords: mTOR, leukemia, myeloid, TORC2

A Chemical Biology Approach to Developing STAT Inhibitors: Molecular Strategies for Accelerating Clinical Translation Research Perspective

Erik A. Nelson, Sreenath V. Sharma, Jeffrey Settleman, David A. Frank

Published Jun 15, 2011 · Vol. 2, No. 6 · pp. 518-524

Keywords: STAT transcription factors, signal transduction, cancer therapy

Strong Inhibition of Xenografted Tumor Growth by Low-Level Doses of [32P]ATP Research Paper

Yulan Cheng, Jian Yang, Rachana Agarwal, Gilbert M. Green, Ron C. Mease, Martin G. Pomper, Stephen J. Meltzer, John M. Abraham

Published Jun 5, 2011 · Vol. 2, No. 6 · pp. 461-466

Keywords: xenografts, inhibition, nude mice

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis Research Paper

Katharina Bluemlein, Nana-Maria GrÃ¼ning, RenÃ© G. Feichtinger, Hans Lehrach, Barbara Kofler, Markus Ralser

Published May 22, 2011 · Vol. 2, No. 5 · pp. 393-400

Keywords: pyruvate kinase, proteomics, cancer metabolism, alternative splicing, Warburg effect.

YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention Research Perspective

Alastair H. Davies, Sandra E. Dunn

Published May 13, 2011 · Vol. 2, No. 5 · pp. 401-406

Keywords: YB-1, HER2, RSK, MAPK signaling, pre-malignancy, Kinex antibody microarray

Netrin-1 overexpression is predictive of ovarian malignancies Research Paper

Anastasios D. Papanastasiou, Georgios Pampalakis, Dionyssios Katsaros, Georgia Sotiropoulou

Published May 2, 2011 · Vol. 2, No. 5 · pp. 363-367

Keywords: Netrin-1 (NTN1), ovarian cancer, biomarker

miRNA signature of schwannomas: Possible role(s) of â€œtumor suppressorâ€ miRNAs in benign tumors Research Perspective

Erdogan Pekcan Erkan, Xandra O. Breakefield, Okay Saydam

Published Mar 30, 2011 · Vol. 2, No. 3 · pp. 265-270

Keywords: miR-7, Tumor suppressor miRNAs, Benign tumors, Schwannomas, Neurofibromatosis 2 (NF2), Ack1

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health Review

William H. Chappell, Linda S. Steelman, Jacquelyn M. Long, Ruth C. Kempf, Stephen L. Abrams, Richard A. Franklin, JÃ¶rg BÃ¤secke, Franca Stivala, Marco Donia, Paolo Fagone, Graziella Malaponte, Maria C. Mazzarino, Ferdinando Nicoletti, Massimo Libra, Danijela Maksimovic-Ivanic, Sanja Mijatovic, Giuseppe Montalto, Melchiorre Cervello, Piotr Laidler, Michele Milella, Agostino Tafuri, Antonio Bonati, Camilla Evangelisti, Lucio Cocco, Alberto M. Martelli, James A. McCubrey

Published Mar 11, 2011 · Vol. 2, No. 3 · pp. 135-164

Keywords: Targeted Therapy, Combination Therapy, Drug Resistance, Cancer Stem Cells, Aging, Senescence, Raf, Akt, PI3K, mTOR

Targeting Translation Dependence in Cancer Research Perspective

Abba Malina, Regina Cencic, Jerry Pelletier

Published Feb 15, 2011 · Vol. 2, No. 1-2 · pp. 76-88

Keywords: Translation, Translational Control, eIF4F, eIF4E, eIF4A, Translation Inhibitor

Tie2/TEK Modulates the Interaction of Glioma and Brain Tumor Stem Cells with Endothelial Cells and Promotes an Invasive Phenotype Research Paper

Dan Liu, Vanesa Martin, Juan Fueyo, Ok-Hee Lee, Jing Xu, Nahir Cortes-Santiago, Marta M. Alonso, Kenneth Aldape, Howard Colman, Candelaria Gomez-Manzano

Published Dec 30, 2010 · Vol. 1, No. 8 · pp. 700-709

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget Research Perspective

Inti Zlobec, Alessandro Lugli

Published Nov 28, 2010 · Vol. 1, No. 7 · pp. 651-661

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Pro-malignant properties of STAT3 during chronic inflammation Editorial Comments

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing Methodological Reports

Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice Brief Reports

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Regression of metastatic melanoma by targeting cancer stem cells Brief Reports

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target Review

Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes Research Paper

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy Research Perspective

Targeting mTOR for the treatment of AML. New agents and new directions. Research Perspective

A Chemical Biology Approach to Developing STAT Inhibitors: Molecular Strategies for Accelerating Clinical Translation Research Perspective

Strong Inhibition of Xenografted Tumor Growth by Low-Level Doses of [32P]ATP Research Paper

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis Research Paper

YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention Research Perspective

Netrin-1 overexpression is predictive of ovarian malignancies Research Paper

miRNA signature of schwannomas: Possible role(s) of â€œtumor suppressorâ€ miRNAs in benign tumors Research Perspective

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health Review

Targeting Translation Dependence in Cancer Research Perspective

Tie2/TEK Modulates the Interaction of Glioma and Brain Tumor Stem Cells with Endothelial Cells and Promotes an Invasive Phenotype Research Paper

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Pro-malignant properties of STAT3 during chronic inflammation Editorial Comments

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing Methodological Reports

Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice Brief Reports

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Regression of metastatic melanoma by targeting cancer stem cells Brief Reports

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target Review

Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes Research Paper

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins Research Paper

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy Research Perspective

Targeting mTOR for the treatment of AML. New agents and new directions. Research Perspective

A Chemical Biology Approach to Developing STAT Inhibitors: Molecular Strategies for Accelerating Clinical Translation Research Perspective

Strong Inhibition of Xenografted Tumor Growth by Low-Level Doses of [32P]ATP Research Paper

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis Research Paper

YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention Research Perspective

Netrin-1 overexpression is predictive of ovarian malignancies Research Paper

miRNA signature of schwannomas: Possible role(s) of â€œtumor suppressorâ€ miRNAs in benign tumors Research Perspective

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health Review

Targeting Translation Dependence in Cancer Research Perspective

Tie2/TEK Modulates the Interaction of Glioma and Brain Tumor Stem Cells with Endothelial Cells and Promotes an Invasive Phenotype Research Paper

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget Research Perspective

miRNA signature of schwannomas: Possible role(s) of â€œtumor suppressorâ€ miRNAs in benign tumors Research Perspective