The Oncosearch | Oncotarget

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Kouki Okita, Shogo Okazaki, Shinya Uejima, Erina Yamada, Hiroki Kaminaka, Misa Kondo, Shiho Ueda, Ryo Tokiwa, Nami Iwata, Akitaka Yamasaki, Natsumi Hayashi, Dai Ogura, Kenji Hirotani, Toshiaki Yoshioka, Masahiro Inoue, Kazue Masuko, Takashi Masuko

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 31-45

Keywords: CDR, HER3, internalization, mAb, NRG1

Probiotic Propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Fillipe Luiz Rosa do Carmo, Houem Rabah, Barbara Fernandes Cordeiro, Sara Heloisa da Silva, Rafaela Miranda Pessoa, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Valérie Gagnaire, Martine Deplanche, Bruna Savassi, Alessandra Figueiroa, Emiliano Rosa Oliveira, Caio César Fonseca, Maria Izabel Alves Queiroz, Núbia Morais Rodrigues, Sávio Henrique de Cicco Sandes, Álvaro Cantini Nunes, Luisa Lemos, Juliana de Lima Alves, Ana Maria Caetano Faria, Ênio Ferreira, Yves Le Loir, Gwénaël Jan, Vasco Azevedo

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7198-7219

Keywords: mucositis, probiotic, surface protein, immunomodulation, inflammation

Nuclear up regulation of the BRCA1-associated ubiquitinase BAP1 is associated with tumor aggressiveness in prostate cancers lacking the TMPRSS2:ERG fusion Research Paper

Stefan Steurer, Lara Schwemmer, Claudia Hube-Magg, Franziska Büscheck, Doris Höflmayer, Maria Christina Tsourlakis, Till S. Clauditz, Andreas M. Luebke, Ronald Simon, Guido Sauter, Jakob Izbicki, Cornelia Schroeder, Thorsten Schlomm, Hartwig Huland, Hans Heinzer, Alexander Haese, Markus Graefen, Cosima Göbel, Sören Weidemann, Patrick Lebok, David Dum, Christoph Fraune, Sarah Minner, Jan Meiners

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7096-7111

Keywords: BAP1, prostate cancer, prognosis, immunohistochemistry

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

Hideyuki Matsushima, Masaki Kaibori, Masahiko Hatta, Morihiko Ishizaki, Richi Nakatake, Tadayoshi Okumura, Kengo Yoshii, Tomoki Todo

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7132-7141

Keywords: oncolytic virus, herpes simplex virus, neuroendocrine tumor, mouse xenograft model

NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis Research Paper

Vasiliki Salameti, Priyanka G. Bhosale, Ashley Ames-Draycott, Kalle Sipilä, Fiona M. Watt

Published Nov 26, 2019 · Vol. 10, No. 63 · pp. 6791-6804

Keywords: oral squamous cell carcinoma (OSCC), NOTCH1, SERPINE1, ETV7/TEL2, cell adhesion

Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent Research Paper

Anne-Julie Cloux, Dominique Aubry, Mathieu Heulot, Christian Widmann, Oussama ElMokh, Francesco Piacente, Michele Cea, Alessio Nencioni, Axel Bellotti, Karima Bouzourène, Maxime Pellegrin, Lucia Mazzolai, Michel A. Duchosal, Aimable Nahimana

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6723-6738

Keywords: tumor cell death, parthanatos, non-apoptotic death, APO866/FK866, NAD

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Chunmei Zhao, Benjamin J. Thompson, Kelly Chen, Feng Gao, Barbara Blouw, Mathieu Marella, Susan Zimmerman, Trevor Kimbler, Sheryl Garrovillo, Jesse Bahn, Lei Huang, Zhongdong Huang, H. Michael Shepard, Sanna Rosengren, Christopher D. Thanos, Daniel C. Maneval

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6561-6576

Keywords: hyaluronan, breast cancer, xenograft, tumor microenvironment, CD44

Correction: Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription Correction

Yuyan Wei, Kai Li, Shaohua Yao, Junping Gao, Jun Li, Yanna Shang, Jie Zhang, Le Zhang, Yanyan Li, Xianming Mo, Wentong Meng, Rong Xiang, Jiankun Hu, Ping Lin, Yuquan Wei

Published Nov 10, 2019 · Vol. 10, No. 67 · pp. 7179-7180

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Fillipe Luiz Rosa do Carmo, Houem Rabah, Barbara Fernandes Cordeiro, Sara Heloisa da Silva, Rafaela Miranda Pessoa, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Valérie Gagnaire, Martine Deplanche, Bruna Savassi, Alessandra Figueiroa, Emiliano Rosa Oliveira, Caio César Fonseca, Maria Izabel Alves Queiroz, Núbia Morais Rodrigues, Sávio Henrique de Cicco Sandes, Álvaro Cantini Nunes, Luisa Lemos, Juliana de Lima Alves, Ana Maria Caetano Faria, Ênio Ferreira, Yves Le Loir, Gwénaël Jan, Vasco Azevedo

Published Nov 5, 2019

Keywords: mucositis, probiotic, surface protein, immunomodulation, inflammation

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Gozde Uzunalli, Alexandra M. Dieterly, Chinyere M. Kemet, Hsin-Yi Weng, Arvin H. Soepriatna, Craig J. Goergen, Aparna B. Shinde, Michael K. Wendt, L. Tiffany Lyle

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6334-6348

Keywords: blood-brain barrier, blood-tumor barrier, non-small cell lung cancer, brain metastasis, aquaporin-4

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition Correction

Esteban A. Terzo, Aaron R. Lim, Anna Chytil, Yun Chen Chiang, Leah Farmer, Kathryn H. Gessner, Cheryl Lyn Walker, Valerie M. Jansen, W. Kimryn Rathmell

Published Oct 22, 2019 · Vol. 10, No. 59 · pp. 6391-6392

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

Abbas Hadji, Greta K. Schmitt, Mathew R. Schnorenberg, Lauren Roach, Connie M. Hickey, Logan B. Leak, Matthew V. Tirrell, James L. LaBelle

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6219-6233

Keywords: MCL-1, BIM, BH3 mimetic, stapled peptides, apoptosis

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Prachi Namjoshi, Lori Showalter, Brian J. Czerniecki, Gary K. Koski

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 6006-6020

Keywords: apoptosis, HER-2, T-helper 1, IFN-γ, TNF-α

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

Mark R. Woodford, Michael Hughes, Rebecca A. Sager, Sarah J. Backe, Alexander J. Baker-Williams, Michael S. Bratslavsky, Joseph M. Jacob, Oleg Shapiro, Michael Wong, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5824-5834

Keywords: tuberous sclerosis complex (TSC), Tsc1 (Hamartin), Tsc2 (Tuberin), heat shock protein (Hsp90), bladder cancer

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Younes Medkour, Karamat Mohammad, Anthony Arlia-Ciommo, Veronika Svistkova, Pamela Dakik, Darya Mitrofanova, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Tarek Taifour, Paola Escudero, Fani-Fay Goltsios, Sahar Soodbakhsh, Hana Maalaoui, Éric Simard, Vladimir I. Titorenko

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5780-5816

Keywords: cellular aging, geroprotectors, lipid metabolism, necrotic cell death, mitochondria

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Amanda M. Smith, Christine R.C. Zhang, Alexandre S. Cristino, John P. Grady, J. Lynn Fink, Andrew S. Moore

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5755-5767

Keywords: myeloid leukemia, therapy, drug resistance, hematological malignancies, gene mutation

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

Rajnish Nagarkar, Darshana Patil, Timothy Crook, Vineet Datta, Sagar Bhalerao, Sonal Dhande, Vijay Palwe, Shirsendu Roy, Prakash Pandit, Ashwini Ghaisas, Raymond Page, Harjeetsingh Kathuria, Ajay Srinivasan, Dadasaheb Akolkar

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5605-5621

Keywords: precision oncology, encyclopedic tumor analysis, personalized cancer treatment, objective response rate, progression free survival

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues Research Paper

Sarah Bonk, Martina Kluth, Claudia Hube-Magg, Adam Polonski, Greta Soekeland, Georgia Makropidi-Fraune, Christina Möller-Koop, Melanie Witt, Andreas M. Luebke, Andrea Hinsch, Eike Burandt, Stefan Steurer, Till S. Clauditz, Thorsten Schlomm, Daniel Perez, Markus Graefen, Hans Heinzer, Hartwig Huland, Jakob R. Izbicki, Waldemar Wilczak, Sarah Minner, Guido Sauter, Ronald Simon

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5439-5453

Keywords: prostate specific antigen, specificity, immunohistochemistry, prognosis marker, tissue microarray

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Younes Medkour, Karamat Mohammad, Anthony Arlia-Ciommo, Veronika Svistkova, Pamela Dakik, Darya Mitrofanova, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Tarek Taifour, Paola Escudero, Fani-Fay Goltsios, Sahar Soodbakhsh, Hana Maalaoui, Éric Simard, Vladimir I. Titorenko

Published Sep 5, 2019

Keywords: cellular aging, geroprotectors, lipid metabolism, necrotic cell death, mitochondria

Targeted drug combination therapy design based on driver genes Research Paper

Lilian Zsákai, Anna Sipos, Judit Dobos, Dániel Erős, Csaba Szántai-Kis, Péter Bánhegyi, János Pató, László Őrfi, Zsolt Matula, Gábor Mikala, György Kéri, István Peták, István Vályi-Nagy

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5255-5266

Keywords: combination therapy, cancer driver gene, primary culture, small molecule compound, multiple myeloma

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Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Probiotic Propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Nuclear up regulation of the BRCA1-associated ubiquitinase BAP1 is associated with tumor aggressiveness in prostate cancers lacking the TMPRSS2:ERG fusion Research Paper

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis Research Paper

Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent Research Paper

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Correction: Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription Correction

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition Correction

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Targeted drug combination therapy design based on driver genes Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Probiotic Propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Nuclear up regulation of the BRCA1-associated ubiquitinase BAP1 is associated with tumor aggressiveness in prostate cancers lacking the TMPRSS2:ERG fusion Research Paper

Efficacy of a third-generation oncolytic herpes simplex virus in neuroendocrine tumor xenograft models Research Paper

NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis Research Paper

Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent Research Paper

The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44 Research Paper

Correction: Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription Correction

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition Correction

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors Research Paper

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial Research Paper

Prognostic and diagnostic role of PSA immunohistochemistry: A tissue microarray study on 21,000 normal and cancerous tissues Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Targeted drug combination therapy design based on driver genes Research Paper