The Oncosearch | Oncotarget

Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study Research Paper

Silvia P. Corona, Fabiola Giudici, Guy Jerusalem, Eva Ciruelos, Carla Strina, Marianna Sirico, Ottavia Bernocchi, Manuela Milani, Martina Dester, Nicoletta Ziglioli, Giuseppina Barbieri, Valeria Cervoni, Filippo Montemurro, Daniele Generali

Published May 19, 2020 · Vol. 11, No. 23 · pp. 2172-2181

Keywords: BMI, weight, everolimus, metastatic breast cancer, outcomes

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Anusha Chaparala, Deepak Poudyal, Hossam Tashkandi, Erin E. Witalison, Alexander A. Chumanevich, Jenna L. Hofseth, Ivy Nguyen, Olivia Hardy, Douglas L. Pittman, Michael D. Wyatt, Anthony Windust, Elizabeth A. Murphy, Mitzi Nagarkatti, Prakash Nagarkatti, Lorne J. Hofseth

Published Apr 30, 2020 · Vol. 11, No. 22 · pp. 2026-2036

Keywords: inflammatory bowel diseases, ulcerative colitis, American ginseng, panaxynol, macrophages

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Carmen J. Narvaez, Erika LaPorta, Samantha Robilotto, Jennifer Liang, JoEllen Welsh

Published Apr 25, 2020 · Vol. 11, No. 30 · pp. 2889-2905

Keywords: vitamin D, hyaluronic acid, hyaluronan synthase, HAS2, breast cancer

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Thao Pham, Kristin Robinson, Terra Vleeshouwer-Neumann, James E. Annis, Eleanor Y. Chen

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1448-1461

Keywords: rhabdomyosarcoma, self-renewal, GRK5, kinase, cell cycle

Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults Research Paper

Hirotomo Yamanashi, Kenji Nagaoki, Sinsuke Kanbara, Yuji Shimizu, Kunihiko Murase, Akira Tsujino, Takahiro Maeda

Published Apr 17, 2020 · Vol. 11, No. 19 · pp. 1705-1713

Keywords: sarcopenia, frailty, handgrip strength, cerebral microbleeds, platelet

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

David J. Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1257-1272

Keywords: SYK inhibitor, breast carcinoma, 3D culture, murine mammary gland, proliferation

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

Loss of p16 and high Ki67 labeling index is associated with poor outcome in esophageal carcinoma Research Paper

Frank Jacobsen, Jacob Kohsar, Florian Gebauer, Martina Kluth, Claudia Hube-Magg, Ronald Simon, Maximilian Bockhorn, Andrea Hinsch, Eike Burandt, Andreas M. Lübke, Stefan Steurer, Michael Tachezy, Guido Sauter, Jacob R. Izbicki, Wildemar Wilczak, Nathaniel Melling

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1007-1016

Keywords: p16, 9p21, esophageal cancer, TMA, prognosis

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Asif Rashid, Xin Duan, Feng Gao, Mengsu Yang, Andrew Yen

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1017-1036

Keywords: ATRA, roscovitine, APL, HL-60, Lyn

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Tomoya Aikawa, Noriko Togashi, Koichi Iwanaga, Hiroyuki Okada, Yumi Nishiya, Shinichi Inoue, Mark J. Levis, Takeshi Isoyama

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 943-955

Keywords: relapsed/refractory AML, FLT3 inhibitors, quizartinib, AC886, midostaurin resistance

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Nicci Owusu-Brackett, Ming Zhao, Argun Akcakanat, Kurt W. Evans, Erkan Yuca, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 969-981

Keywords: PI3Kβ, PTEN loss, AZD8186, chemotherapy, immunotherapy

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Stefanie Schlager, Carina Salomon, Sabine Olt, Christoph Albrecht, Anja Ebert, Oliver Bergner, Johannes Wachter, Francesca Trapani, Daniel Gerlach, Tilman Voss, Anna Traunbauer, Julian Jude, Matthias Hinterndorfer, Martina Minnich, Norbert Schweifer, Sophia M. Blake, Vittoria Zinzalla, Barbara Drobits, Darryl B. McConnell, Norbert Kraut, Mark Pearson, Johannes Zuber, Manfred Koegl

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 875-890

Keywords: BCL6, DLBCL, lymphoma, inducible CRISPR/Cas9, in vivo xenograft

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Ajay Kale, Afaf Aldahish, Girish Shah

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 858-874

Keywords: calcitonin receptor, T-antigen, tumor growth, PTEN, prostate cancer

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Stephanie L. Merrigan, Bomina Park, Zaheer Ali, Lasse D. Jensen, Timothy W. Corson, Breandán N. Kennedy

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 493-509

Keywords: developmental angiogenesis, pathological angiogenesis, ocular angiogenesis, calcitriol, 22-oxacalcitriol

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Evan A. Clayton, Shareef Khalid, Dongjo Ban, Lu Wang, I. King Jordan, John F. McDonald

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 462-479

Keywords: allele-specific expression, alternative splicing, antisense RNA, cancer, tumor-suppressor genes

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Ling F. Ye, Eduard Reznik, Joshua M. Korn, Fallon Lin, Guizhi Yang, Kimberly Malesky, Hui Gao, Alice Loo, Raymond Pagliarini, Tom Mikkelsen, Donald C. Lo, Ana C. deCarvalho, Brent R. Stockwell

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 443-451

Keywords: cell death, chemical biology, glioma, cancer

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Tal Feldman, Iris Grossman-Haham, Yoav Elkis, Patrick Vilela, Neta Moskovits, Iris Barshack, Tomer M. Salame, Deborah Fass, Tal Ilani

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 386-398

Keywords: monoclonal antibody inhibitor, tumor microenvironment, fibroblasts, extracellular matrix remodeling, disulfide bonds

Stratifying the stratifiers of triple negative breast cancer Editorial

Dong-Yu Wang, Zhe Jiang, Eldad Zacksenhaus

Published Jan 18, 2020 · Vol. 11, No. 4 · pp. 306-308

Keywords: triple negative breast cancer, molecular stratification, prognostication, microRNA, immunomodulation

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

Zi-Jia Khong, Soak-Kuan Lai, Cheng-Gee Koh, Susana Geifman-Shochat, Hoi-Yeung Li

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 74-85

Keywords: p97/VCP, AAA-ATPase, ROCK, RhoA, cell motility

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study Research Paper

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Loss of p16 and high Ki67 labeling index is associated with poor outcome in esophageal carcinoma Research Paper

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Stratifying the stratifiers of triple negative breast cancer Editorial

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Impact of BMI on the outcome of metastatic breast cancer patients treated with everolimus: a retrospective exploratory analysis of the BALLET study Research Paper

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Relationships of handgrip strength with the presence of cerebral microbleeds and platelet count in older Japanese adults Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Loss of p16 and high Ki67 labeling index is associated with poor outcome in esophageal carcinoma Research Paper

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models Research Paper

Stratifying the stratifiers of triple negative breast cancer Editorial

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper