The Oncosearch | Oncotarget

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

Nikhil Gupta, Jung Eun Park, Wilford Tse, Jee Keem Low, Oi Lian Kon, Neil McCarthy, Siu Kwan Sze

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5970-5982

Keywords: pancreatic cancer, hypoxia tumor, ERO1α, SILAC, proteomics

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Prachi Namjoshi, Lori Showalter, Brian J. Czerniecki, Gary K. Koski

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 6006-6020

Keywords: apoptosis, HER-2, T-helper 1, IFN-γ, TNF-α

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

Shiho Fukui, Kazunori Nagasaka, Yuko Miyagawa, Ryoko Kikuchi-Koike, Yoshiko Kawata, Ranka Kanda, Takayuki Ichinose, Takeru Sugihara, Haruko Hiraike, Osamu Wada-Hiraike, Yuko Sasajima, Takuya Ayabe

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5932-5948

Keywords: ovarian cancer, bAP15, TGF-β/Smad signaling, UCHL5, apoptosis

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Luana de O. Lopes, Jersey H. Maués, Hygor Ferreira-Fernandes, France K. Yoshioka, Severino C. Sousa Júnior, Alcemir R. Santos, Helem F. Ribeiro, Juan A. Rey, Paulo C. Soares, Rommel R. Burbano, Giovanny R. Pinto

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5768-5779

Keywords: stomach neoplasms, MYC oncogene, transcriptome, gene expression profiling, prognosis

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma Research Paper

Nathan D. Seligson, Colin W. Stets, Bryce W. Demoret, Achal Awasthi, Nicholas Grosenbacher, Reena Shakya, John L. Hays, James L. Chen

Published Oct 1, 2019 · Vol. 10, No. 55 · pp. 5671-5679

Keywords: dedifferentiated liposarcomas, MDM2, HDAC2, romidepsin, MI-192

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Balaji Krishnamachary, Dharmalingam Subramaniam, Prasad Dandawate, Sivapriya Ponnurangam, Pugazhendhi Srinivasan, Prabhu Ramamoorthy, Shahid Umar, Sufi Mary Thomas, Animesh Dhar, Seth Septer, Scott J. Weir, Thomas Attard, Shrikant Anant

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5576-5591

Keywords: Wnt signaling, beta-catenin, natural product, tumor xenograft, preventive agent

Consuming cholera toxin counteracts age-associated obesity Research Paper

Bernard J. Varian, Theofilos Poutahidis, Gordon Haner, Alex Hardas, Vanessa Lau, Susan E. Erdman

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5497-5509

Keywords: body weight, mouse, exotoxin subunit B, CLS, inflammation

Excision repair cross-complementing group-1 (ERCC1) induction kinetics and polymorphism are markers of inferior outcome in patients with colorectal cancer treated with oxaliplatin Research Paper

Devika Rao, Atrayee Basu Mallick, Titto Augustine, Cecilia Daroqui, Jeeshan Jiffry, Amartej Merla, Imran Chaudhary, Raviraja Seetharam, Arjun Sood, Srikanth Gajavelli, Santiago Aparo, Lakshmi Rajdev, Andreas Kaubisch, Jennifer Chuy, Abdissa Negassa, John M. Mariadason, Radhashree Maitra, Sanjay Goel

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5510-5522

Keywords: oxaliplatin, colorectal cancer, ERCC1, FOLFOX, resistance

Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice Research Paper

Yuji Ueda, Koichi Kawamoto, Masamitsu Konno, Kozo Noguchi, Satoru Kaifuchi, Taroh Satoh, Hidetoshi Eguchi, Yuichiro Doki, Takaaki Hirotsu, Masaki Mori, Hideshi Ishii

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5412-5418

Keywords: early detection, pancreatic cancer, C. elegans, genetically-engineered mice

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Milos Mihajlovic, Sam Hariri, Koen C.G. Westphal, Manoe J. Janssen, Miriam J. Oost, Laura Bongiovanni, Lambertus P. van den Heuvel, Alain de Bruin, Luuk B. Hilbrands, Rosalinde Masereeuw

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5332-5348

Keywords: bioartificial kidney, cell therapy safety, conditionally immortalized proximal tubule epithelial cells, tumorigenicity, viral integration

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis Research Paper

Andrey V. Markov, Alexander E. Kel, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Evgeniya B. Logashenko

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5267-5297

Keywords: soloxolone methyl, cervical carcinoma, CDDO-Me, cytoscape, mechanism of action

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Jennifer Bourn, Sony Pandey, Jashim Uddin, Lawrence Marnett, Maria Cekanova

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5168-5180

Keywords: bladder cancer, TKIs, RTKIs, COX-2, targeted therapies

Contemplations on MDMX (MDM4) driving triple negative breast cancer circulating tumor cells and metastasis Research Perspective

Chong Gao, Gu Xiao, Jill Bargonetti

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5007-5010

Keywords: MDMX, MDM4, mutant p53, mtp53, metastasis

Methylation alteration of SHANK1 as a predictive, diagnostic and prognostic biomarker for chronic lymphocytic leukemia Research Paper

Eleonora Loi, Loredana Moi, Antonio Fadda, Giannina Satta, Mariagrazia Zucca, Sonia Sanna, Shadi Amini Nia, Giuseppina Cabras, Marina Padoan, Corrado Magnani, Lucia Miligi, Sara Piro, Davide Gentilini, Maria Grazia Ennas, Melissa C. Southey, Graham G. Giles, Nicole Wong Doo, Pierluigi Cocco, Patrizia Zavattari

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4987-5002

Keywords: cancer methylation alteration, predictive biomarkers, diagnostic biomarkers, prognostic biomarkers, SHANK1

MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma Research Paper

Ryo Yokomizo, Nozomu Yanaihara, Noriko Yamaguchi, Misato Saito, Ayako Kawabata, Kazuaki Takahashi, Masataka Takenaka, Kyosuke Yamada, Jason Solomon Shapiro, Aikou Okamoto

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4880-4893

Keywords: ovarian high-grade serous carcinoma, miR-34a, IL-6R, STAT3, p53

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

Letícia Scussel Bergamin, Marina Capece, Erica Salaro, Alba Clara Sarti, Simonetta Falzoni, Mery Stéfani Leivas Pereira, Marco Antônio De Bastiani, Juliete Nathali Scholl, Ana Maria O. Battastini, Francesco Di Virgilio

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4840-4856

Keywords: cancer, glioma, P2X7R, purinergic signaling, extracellular ATP

Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells Research Paper

Kazuo Asanoma, Emiko Hori, Sachiko Yoshida, Hiroshi Yagi, Ichiro Onoyama, Keisuke Kodama, Masafumi Yasunaga, Tatsuhiro Ohgami, Eisuke Kaneki, Kaoru Okugawa, Hideaki Yahata, Kiyoko Kato

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4640-4654

Keywords: microRNA, transcription factor, epithelial-to-mesenchymal transition, cell invasion, endometrial cancer

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Mary K. Nesline, Paul DePietro, Grace K. Dy, Amy Early, Antonios Papanicolau-Sengos, Jeffrey M. Conroy, Felicia L. Lenzo, Sean T. Glenn, Hongbin Chen, Anne Grand’Maison, Patrick Boland, Marc S. Ernstoff, Igor Puzanov, Stephen Edge, Stacey Akers, Mateusz Opyrchal, Gurkamal Chatta, Kunle Odunsi, Peter Frederick, Shashikant Lele, Mark Gardner, Carl Morrison

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4616-4629

Keywords: comprehensive genomic profiling, targeted therapy, clinical decision making, next-generation sequencing, real world data

Nerve-sparing versus non-nerve-sparing radical hysterectomy: surgical and long-term oncological outcomes Research Paper

Antonio Gil-Moreno, Melchor Carbonell-Socias, Sabina Salicrú, Melissa Bradbury, Ángel García, Ramona Vergés, Oriol Puig Puig, José Luís Sánchez-Iglesias, Silvia Cabrera-Díaz, Javier de la Torre, Natalia R. Gómez-Hidalgo, Assumpció Pérez-Benavente, Berta Díaz-Feijoo

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4598-4608

Keywords: cervical cancer, morbidity, recurrence, surgical treatment, survival

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Laila Babar, Juliann E. Kosovec, Vida Jahangiri, Nobel Chowdhury, Ping Zheng, Ashten N. Omstead, Madison S. Salvitti, Matthew A. Smith, Ajay Goel, Ronan J. Kelly, Blair A. Jobe, Ali H. Zaidi

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4546-4555

Keywords: esophageal adenocarcinoma, LAG3, IDO1, CXCL9, TIM3

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ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma Research Paper

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Consuming cholera toxin counteracts age-associated obesity Research Paper

Excision repair cross-complementing group-1 (ERCC1) induction kinetics and polymorphism are markers of inferior outcome in patients with colorectal cancer treated with oxaliplatin Research Paper

Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Contemplations on MDMX (MDM4) driving triple negative breast cancer circulating tumor cells and metastasis Research Perspective

Methylation alteration of SHANK1 as a predictive, diagnostic and prognostic biomarker for chronic lymphocytic leukemia Research Paper

MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma Research Paper

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells Research Paper

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Nerve-sparing versus non-nerve-sparing radical hysterectomy: surgical and long-term oncological outcomes Research Paper

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line Research Paper

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma Research Paper

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone Research Paper

Consuming cholera toxin counteracts age-associated obesity Research Paper

Excision repair cross-complementing group-1 (ERCC1) induction kinetics and polymorphism are markers of inferior outcome in patients with colorectal cancer treated with oxaliplatin Research Paper

Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Contemplations on MDMX (MDM4) driving triple negative breast cancer circulating tumor cells and metastasis Research Perspective

Methylation alteration of SHANK1 as a predictive, diagnostic and prognostic biomarker for chronic lymphocytic leukemia Research Paper

MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma Research Paper

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells Research Paper

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Nerve-sparing versus non-nerve-sparing radical hysterectomy: surgical and long-term oncological outcomes Research Paper

Prognostic immune markers for recurrence and survival in locally advanced esophageal adenocarcinoma Research Paper