The Oncosearch | Oncotarget

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Rodney J. Scott, Anurag Mehta, Gabriel S. Macedo, Pavel S. Borisov, Ravindran Kanesvaran, Wafaa El Metnawy

Published Jun 22, 2021 · Vol. 12, No. 16 · pp. 1600-1614

Keywords: metastatic castration-resistant prostate cancer, homologous recombination repair, next generation sequencing, genetic testing

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Tara Williamson, Michelle Carvalho de Abreu, Dimitri G. Trembath, Cory Brayton, Byunghak Kang, Thais Biude Mendes, Paulo Pimentel de Assumpção, Janete M. Cerutti, Gregory J. Riggins

Published Jun 22, 2021 · Vol. 12, No. 14 · pp. 1326-1338

Keywords: mebendazole, pancreatic cancer, cancer prevention, metastasis, mouse models

Undetected Barrett’s esophagus: how do we improve early detection? Editorial

Holli A. Loomans-Kropp, Ellen Richmond

Published Jun 19, 2021 · Vol. 12, No. 24 · pp. 2418-2420

Keywords: Barrett's esophagus, esophageal adenocarcinoma, screening, concurrent disease

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Catherine T. Haring, Chandan Bhambhani, Collin Brummel, Brittany Jewell, Emily Bellile, Molly E. Heft Neal, Erin Sandford, Ryan M. Spengler, Apurva Bhangale, Matthew E. Spector, Jonathan McHugh, Mark E. Prince, Michelle Mierzwa, Francis P. Worden, Muneesh Tewari, Paul L. Swiecicki, J. Chad Brenner

Published Jun 11, 2021 · Vol. 12, No. 13 · pp. 1214-1229

Keywords: HPV, head and neck cancer, oropharyngeal cancer, ctDNA, circulating tumor DNA

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

Anjan Thakurta, William E. Pierceall, Michael D. Amatangelo, Erin Flynt, Amit Agarwal

Published May 19, 2021 · Vol. 12, No. 15 · pp. 1555-1563

Keywords: multiple myeloma, combinations, immunomodulatory agents, apoptosis, protein degradation

Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma Research Paper

Chiara Colarusso, Michela Terlizzi, Anne-Sophie Lamort, Ida Cerqua, Fiorentina Roviezzo, Georgios Stathopoulos, Aldo Pinto, Rosalinda Sorrentino

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1057-1071

Keywords: smoke, COPD, lung cancer, lung inflammation, inflammasome

Perioperative changes in the plasma metabolome of patients receiving general anesthesia for pancreatic cancer surgery Research Paper

Johanna Mock-Ohnesorge, Andreas Mock, Thilo Hackert, Stefan Fröhling, Judith Schenz, Gernot Poschet, Dirk Jäger, Markus W. Büchler, Florian Uhle, Markus A. Weigand

Published Apr 25, 2021 · Vol. 12, No. 10 · pp. 996-1010

Keywords: metabolomics, anesthesia, plasma, tumor, longitudinal

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Josephine Dubois, Jacqueline Rueger, Bernhard Haubold, Rosel Kretschmer-Kazemi Far, Georg Sczakiel

Published Apr 24, 2021 · Vol. 12, No. 10 · pp. 1011-1023

Keywords: tumor diagnostics, non-invasive, urine RNA, biomarker, transcriptome analysis

Multigene tests for breast cancer: the physician’s perspective Review

Francesco Cognetti, Laura Biganzoli, Sabino De Placido, Lucia del Mastro, Riccardo Masetti, Giuseppe Naso, Giancarlo Pruneri, Donatella Santini, Carlo Alberto Tondini, Corrado Tinterri, Giuseppe Tonini, Sandro Barni

Published Apr 8, 2021 · Vol. 12, No. 9 · pp. 936-947

Keywords: genomic tests, breast cancer, adjuvant chemotherapy, adjuvant hormone therapy

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Yehia I. Mohamed, Sunyoung Lee, Lianchun Xiao, Manal M. Hassan, Aliya Qayyum, Rikita Hiatia, Roberto Carmagnani Pestana, Abedul Haque, Bhawana George, Asif Rashid, Dan G. Duda, Hesham Elghazaly, Robert A. Wolff, Jeffrey S. Morris, James Yao, Hesham M. Amin, Ahmed O. Kaseb

Published Mar 13, 2021 · Vol. 12, No. 8 · pp. 756-766

Keywords: IGF-1, Child-Pugh, sorafenib, liver reserve, hepatocellular carcinoma

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Brittany Mull, Ryan Davis, Iqbal Munir, Mia C. Perez, Alfred A. Simental, Salma Khan

Published Mar 12, 2021 · Vol. 12, No. 7 · pp. 596-607

Keywords: DBP, thyroid cancer, health disparities

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models Research Paper

Helena Degroote, Sander Lefere, Astrid Vandierendonck, Bart Vanderborght, Tim Meese, Filip Van Nieuwerburgh, Xavier Verhelst, Anja Geerts, Hans Van Vlierberghe, Lindsey Devisscher

Published Feb 20, 2021 · Vol. 12, No. 6 · pp. 562-577

Keywords: hepatocellular carcinoma, macrophage subsets, tumor microenvironment, tumor associated macrophages, inflammation

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Juan Pablo Cerapio, Agnès Marchio, Luis Cano, Ignacio López, Jean-Jacques Fournié, Béatrice Régnault, Sandro Casavilca-Zambrano, Eloy Ruiz, Anne Dejean, Stéphane Bertani, Pascal Pineau

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 475-492

Keywords: hepatitis B virus, indigenous people, integrative genomics, liver cancer

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Alison Durham, Nicholas J. Donato, Moshe Talpaz

Published Jan 12, 2021 · Vol. 12, No. 3 · pp. 160-172

Keywords: melanoma, deubiquitinase (DUB) enzyme, transcription factors, USP9X, DUB inhibitor

Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell lines Research Paper

Jan Roška, Lenka Wachsmannová, Lenka Hurbanová, Zuzana Šestáková, Thomas Mueller, Dana Jurkovičová, Miroslav Chovanec

Published Dec 5, 2020 · Vol. 11, No. 51 · pp. 4735-4753

Keywords: gene expression array, cisplatin, testicular germ cell tumors, prognostic biomarkers, pluripotency factors

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

Ahmad A. Nazem, Jacob Ruzevick, Manuel J. Ferreira Jr

Published Dec 2, 2020 · Vol. 11, No. 49 · pp. 4544-4553

Keywords: meningioma, skull base, NGS, sequencing, biomarker

miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells Research Paper

Nicholas J. Monteleone, Carol S. Lutz

Published Dec 1, 2020 · Vol. 11, No. 51 · pp. 4699-4721

Keywords: miR-708-5p, miR-708, erlotinib, paclitaxel, chemoresistance

Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma: a SEER population-based study Research Paper

Nimrod Adatto Levy, Guy Kern, Daniel Shepshelovich, Oren Shibolet, Rami Hershkoviz, Ofer Isakov

Published Nov 11, 2020 · Vol. 11, No. 47 · pp. 4438-4447

Keywords: liver fibrosis, cholangiocarcinoma, SEER, survival, cirrhosis

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

Fatemeh Rajabi, Win-Yan Liu-Bordes, Marina Pinskaya, Foretek Dominika, Gueorgui Kratassiouk, Guillaume Pinna, Simona Nanni, Antonella Farsetti, Christian Gespach, Arturo Londoño-Vallejo, Irina Groisman

Published Nov 4, 2020 · Vol. 11, No. 45 · pp. 4155-4168

Keywords: miR-145-5p, TWIST1, CPEB1, EMT, prostate cancer

Baseline CD44v6-positive circulating tumor cells to predict first-line treatment failure in patients with metastatic colorectal cancer Research Paper

Chiara Nicolazzo, Flavia Loreni, Salvatore Caponnetto, Valentina Magri, Anna Rita Vestri, Rita Zamarchi, Angela Gradilone, Antonella Facchinetti, Elisabetta Rossi, Enrico Cortesi, Paola Gazzaniga

Published Oct 24, 2020 · Vol. 11, No. 45 · pp. 4115-4122

Keywords: cancer stem cells, CD44v6, circulating tumor cells, colorectal cancer, CellSearch^®

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Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Undetected Barrett’s esophagus: how do we improve early detection? Editorial

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma Research Paper

Perioperative changes in the plasma metabolome of patients receiving general anesthesia for pancreatic cancer surgery Research Paper

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Multigene tests for breast cancer: the physician’s perspective Review

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models Research Paper

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell lines Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells Research Paper

Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma: a SEER population-based study Research Paper

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

Baseline CD44v6-positive circulating tumor cells to predict first-line treatment failure in patients with metastatic colorectal cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Undetected Barrett’s esophagus: how do we improve early detection? Editorial

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma Research Paper

Perioperative changes in the plasma metabolome of patients receiving general anesthesia for pancreatic cancer surgery Research Paper

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Multigene tests for breast cancer: the physician’s perspective Review

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models Research Paper

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell lines Research Paper

Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies Research Perspective

miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells Research Paper

Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma: a SEER population-based study Research Paper

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

Baseline CD44v6-positive circulating tumor cells to predict first-line treatment failure in patients with metastatic colorectal cancer Research Paper