The Oncosearch | Oncotarget

Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation Research Paper

Hyung Kwon Byeon, Hwi Jung Na, Yeon Ju Yang, Sooah Ko, Sun Och Yoon, Minhee Ku, Jaemoon Yang, Jae Wook Kim, Myung Jin Ban, Ji-Hoon Kim, Da Hee Kim, Jung Min Kim, Eun Chang Choi, Chang-Hoon Kim, Joo-Heon Yoon, Yoon Woo Koh

Published Nov 21, 2016 · Vol. 8, No. 1 · pp. 596-609

Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma Research Paper

Manoj Garg, Deepika Kanojia, Anand Mayakonda, Jonathan W. Said, Ngan B. Doan, Wenwen Chien, Trivadi S Ganesan, Linda Shyue Huey Chuang, Nachiyappan Venkatachalam, Erkan Baloglu, Sharon Shacham, Michael Kauffman, H. Phillip Koeffler

Published Nov 21, 2016 · Vol. 8, No. 5 · pp. 7521-7532

The role of p53 in cancer drug resistance and targeted chemotherapy Review

Karin Hientz, AndrÃ© Mohr, Dipita Bhakta-Guha, Thomas Efferth

Published Nov 19, 2016 · Vol. 8, No. 5 · pp. 8921-8946

EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction Research Paper

Nesaretnam Barr Kumarakulasinghe, Nicholas Syn, Yu Yang Soon, Atasha Asmat, Huili Zheng, En Yun Loy, Brendan Pang, Ross Andrew Soo

Published Nov 19, 2016 · Vol. 7, No. 51 · pp. 85542-85550

Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption Research Paper

Haijun Zhao, Pengcheng Shi, Manman Deng, Zhiwu Jiang, Yin Li, Vinodh Kannappan, Weiguang Wang, Peng Li, Bing Xu

Published Nov 19, 2016 · Vol. 7, No. 51 · pp. 85515-85528

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer Research Paper

Rebecca C. Arend, Angelina I. LondoÃ±o-Joshi, Abhishek Gangrade, Ashwini A. Katre, Chandrika Kurpad, Yonghe Li, Rajeev S. Samant, Pui-Kai Li, Charles N. Landen, Eddy S. Yang, Bertha Hidalgo, Ronald D. Alvarez, John Michael Straughn, Andres Forero, Donald J. Buchsbaum

Published Nov 19, 2016 · Vol. 7, No. 52 · pp. 86803-86815

miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis Research Paper

Shlomit Kfir-Erenfeld, Noa Haggiag, Moshe Biton, Polina Stepensky, Nathalie Assayag-Asherie, Eitan Yefenof

Published Nov 18, 2016 · Vol. 8, No. 1 · pp. 472-489

New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status Research Paper

Muhammad Altaf, Muhammad Monim-ul-Mehboob, Abdel-Nasser Kawde, Giuseppe Corona, Roberto Larcher, Marcia Ogasawara, Naike Casagrande, Marta Celegato, Cinzia Borghese, Zahid H. Siddik, Donatella Aldinucci, Anvarhusein A. Isab

Published Nov 18, 2016 · Vol. 8, No. 1 · pp. 490-505

Sulforaphane inhibits proliferation and invasive activity of everolimus-resistant kidney cancer cells in vitro Research Paper

Eva Juengel, Sebastian Maxeiner, Jochen Rutz, Saira Justin, Frederik Roos, Wael Khoder, Igor Tsaur, Karen Nelson, Wolf O. Bechstein, Axel Haferkamp, Roman A. Blaheta

Published Nov 17, 2016 · Vol. 7, No. 51 · pp. 85208-85219

In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma Research Paper

Ziyan Y. Pessetto, Bin Chen, Hani Alturkmani, Stephen Hyter, Colleen A. Flynn, Michael Baltezor, Yan Ma, Howard G. Rosenthal, Kathleen A. Neville, Scott J. Weir, Atul J. Butte, Andrew K. Godwin

Published Nov 16, 2016 · Vol. 8, No. 3 · pp. 4079-4095

Inhibition of oxidative phosphorylation suppresses the development of osimertinib resistance in a preclinical model of EGFR-driven lung adenocarcinoma Research Paper

Matthew J. Martin, Cath Eberlein, Molly Taylor, Susan Ashton, David Robinson, Darren Cross

Published Nov 16, 2016 · Vol. 7, No. 52 · pp. 86313-86325

Octreotide-periplocymarin conjugate prodrug for improving targetability and anti-tumor efficiency: synthesis, in vitro and in vivo evaluation Research Paper

Hui-Yun Zhang, Wen-Qian Xu, Yuan-yuan Zheng, Emmanuel Omari-Siaw, Yuan Zhu, Xia Cao, Shan-Shan Tong, Jiang-nan Yu, Xi-ming Xu

Published Nov 16, 2016 · Vol. 7, No. 52 · pp. 86326-86338

Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy Research Paper

Tingting Feng, Wei Cao, Wanxiang Shen, Liang Zhang, Xinsheng Gu, Yang Guo, Hsiang-i Tsai, Xuewen Liu, Jian Li, Jingxuan Zhang, Shan Li, Fuyun Wu, Ying Liu

Published Nov 16, 2016 · Vol. 8, No. 1 · pp. 329-344

E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3KÎ² silencing Research Paper

Ãfrica MillÃ¡n-UclÃ©s, Susana Zuluaga, Miriam MarquÃ©s, Jesus Vallejo-DÃaz, Lorena Sanz, Ariel E. Cariaga-MartÃnez, Francisco X. Real, Ana C. Carrera

Published Nov 16, 2016 · Vol. 7, No. 51 · pp. 84054-84071

Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing Priority Research Paper

Ruowen Zhang, Jiahui Wu, Sylvain Ferrandon, Katie J. Glowacki, Janet A. Houghton

Published Nov 15, 2016 · Vol. 7, No. 49 · pp. 80190-80207

Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species Research Paper

Yong-Cheng Ma, Yu Ke, Xiaolin Zi, Fei Zhao, Lin Yuan, Ying-Li Zhu, Xia-Xia Fan, Ning-Min Zhao, Qiao-Yan Li, Yu-Hua Qin, Hong-Min Liu

Published Nov 15, 2016 · Vol. 7, No. 52 · pp. 86211-86224

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer Research Paper

Tae Woo Kim, Seon-Jin Lee, Jong-Tae Kim, Sun Jung Kim, Jeong-Ki Min, Kwang-Hee Bae, Haiyoung Jung, Bo-Yeon Kim, Jong-Seok Lim, Young Yang, Do-Young Yoon, Yong-Kyung Choe, Hee Gu Lee

Published Nov 15, 2016 · Vol. 7, No. 51 · pp. 85332-85348

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma Research Paper

Valerie B. Sampson, Nancy S. Vetter, Wendong Zhang, Pratima U. Patil, Robert W. Mason, Erika George, Richard Gorlick, Edward A. Kolb

Published Nov 15, 2016 · Vol. 7, No. 52 · pp. 86594-86607

Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas Research Paper

Jayshree L. Hirpara, Thomas Loh, Siok Bian Ng, Wee Joo Chng, Shazib Pervaiz

Published Nov 14, 2016 · Vol. 7, No. 51 · pp. 83964-83975

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFÎ²2-bioenergetics-mitochondrial priming Priority Research Paper

Praveena S. Thiagarajan, Xiaoliang Wu, Wei Zhang, Ivy Shi, Rakesh Bagai, Patrick Leahy, Yan Feng, Martina Veigl, Daniel Lindner, David Danielpour, Lihong Yin, Rafael Rosell, Trever G. Bivona, Zhenfeng Zhang, Patrick C. Ma

Published Nov 11, 2016 · Vol. 7, No. 50 · pp. 82013-82027

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Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation Research Paper

Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma Research Paper

The role of p53 in cancer drug resistance and targeted chemotherapy Review

EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction Research Paper

Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption Research Paper

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer Research Paper

miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis Research Paper

New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status Research Paper

Sulforaphane inhibits proliferation and invasive activity of everolimus-resistant kidney cancer cells in vitro Research Paper

In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma Research Paper

Inhibition of oxidative phosphorylation suppresses the development of osimertinib resistance in a preclinical model of EGFR-driven lung adenocarcinoma Research Paper

Octreotide-periplocymarin conjugate prodrug for improving targetability and anti-tumor efficiency: synthesis, in vitro and in vivo evaluation Research Paper

Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy Research Paper

E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3KÎ² silencing Research Paper

Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing Priority Research Paper

Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species Research Paper

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer Research Paper

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma Research Paper

Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas Research Paper

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFÎ²2-bioenergetics-mitochondrial priming Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation Research Paper

Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma Research Paper

The role of p53 in cancer drug resistance and targeted chemotherapy Review

EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction Research Paper

Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption Research Paper

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer Research Paper

miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis Research Paper

New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status Research Paper

Sulforaphane inhibits proliferation and invasive activity of everolimus-resistant kidney cancer cells in vitro Research Paper

In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma Research Paper

Inhibition of oxidative phosphorylation suppresses the development of osimertinib resistance in a preclinical model of EGFR-driven lung adenocarcinoma Research Paper

Octreotide-periplocymarin conjugate prodrug for improving targetability and anti-tumor efficiency: synthesis, in vitro and in vivo evaluation Research Paper

Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy Research Paper

E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3KÎ² silencing Research Paper

Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing Priority Research Paper

Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species Research Paper

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer Research Paper

Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma Research Paper

Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas Research Paper

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFÎ²2-bioenergetics-mitochondrial priming Priority Research Paper