The Oncosearch | Oncotarget

Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer Research Paper

Zhijie Ding, Yuanzhi Lao, Hong Zhang, Wenwei Fu, Lunlun Zhu, Hongsheng Tan, Hongxi Xu

Published Dec 7, 2015 · Vol. 7, No. 2 · pp. 1826-1837

A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds Research Paper

Marsha L. Crochiere, Erkan Baloglu, Boris Klebanov, Scott Donovan, Diego del Alamo, Margaret Lee, Michael Kauffman, Sharon Shacham, Yosef Landesman

Published Dec 7, 2015 · Vol. 7, No. 2 · pp. 1863-1877

ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer Research Paper

Ching-Chia Li, Juan-Cheng Yang, Mei-Chin Lu, Chia-Lin Lee, Chieh-Yu Peng, Wei-Yu Hsu, Yun-Hao Dai, Fang-Rong Chang, Da-Yong Zhang, Wen-Jeng Wu, Yang-Chang Wu

Published Dec 5, 2015 · Vol. 7, No. 2 · pp. 1947-1959

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol Research Paper

Guihua Sun, Ya-Wen Cheng, Lily Lai, Tsui-Chin Huang, Jinhui Wang, Xiwei Wu, Yafan Wang, Yasheng Huang, Jinghan Wang, Keqiang Zhang, Shuya Hu, Ji-Rui Yang, Yun Yen

Published Dec 4, 2015 · Vol. 7, No. 4 · pp. 3857-3872

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

Serguei A. Gordeev, Tatiana V. Bykova, Svetlana G. Zubova, Olga A. Bystrova, Marina G. Martynova, Valery A. Pospelov, Tatiana V. Pospelova

Published Dec 4, 2015 · Vol. 6, No. 42 · pp. 44905-44926

NF-Y activates genes of metabolic pathways altered in cancer cells Research Paper

Paolo Benatti, Maria Luisa Chiaramonte, Mariangela Lorenzo, John A. Hartley, Daniel Hochhauser, Nerina Gnesutta, Roberto Mantovani, Carol Imbriano, Diletta Dolfini

Published Dec 3, 2015 · Vol. 7, No. 2 · pp. 1633-1650

Antihypertensive treatments in adult autosomal dominant polycystic kidney disease: network meta-analysis of the randomized controlled trials Research Paper

Cheng Xue, Chenchen Zhou, Bing Dai, Shengqiang Yu, Chenggang Xu, Zhiguo Mao, Chaoyang Ye, Dongping Chen, Xuezhi Zhao, Jun Wu, Wansheng Chen, Changlin Mei

Published Dec 2, 2015 · Vol. 6, No. 40 · pp. 42515-42529

Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-Î²1 signaling pathway Research Paper

Sangmin Kim, Jeongmin Lee, Myeongjin Jeon, Jeong Eon Lee, Seok Jin Nam

Published Nov 30, 2015 · Vol. 7, No. 2 · pp. 1544-1558

Antibiotic drug tigecycline inhibits melanoma progression and metastasis in a p21CIP1/Waf1-dependent manner Research Paper

Huanrong Hu, Zhen Dong, Peng Tan, Yanli Zhang, Lichao Liu, Liqun Yang, Yaling Liu, Hongjuan Cui

Published Nov 28, 2015 · Vol. 7, No. 3 · pp. 3171-3185

Metformin suppresses hypoxia-induced stabilization of HIF-1Î± through reprogramming of oxygen metabolism in hepatocellular carcinoma Research Paper

Xinke Zhou, Jitao Chen, Gao Yi, Min Deng, Hao Liu, Min Liang, Boyun Shi, Xin Fu, Yuqin Chen, Liangcai Chen, Zhimin He, Jian Wang, Jifang Liu

Published Nov 28, 2015 · Vol. 7, No. 1 · pp. 873-884

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability Research Paper

Min-Wu Chao, Po-Chen Chu, Hsiao-Ching Chuang, Fang-Hsiu Shen, Chih-Chien Chou, En-Chi Hsu, Lauren E. Himmel, Han-Li Huang, Huang-Ju Tu, Samuel K. Kulp, Che-Ming Teng, Ching-Shih Chen

Published Nov 28, 2015 · Vol. 7, No. 2 · pp. 1796-1807

Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy Research Paper

Ruud Weijer, Mans Broekgaarden, Massis Krekorian, Lindy K. Alles, Albert C. van Wijk, Claire Mackaaij, Joanne Verheij, Allard C. van der Wal, Thomas M. van Gulik, Gert Storm, Michal Heger

Published Nov 27, 2015 · Vol. 7, No. 3 · pp. 3341-3356

Melatonin inhibits AP-2Î²/hTERT, NF-ÎºB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells Research Paper

Jian-Jun Lu, Lingyi Fu, Zhipeng Tang, Changlin Zhang, Lijun Qin, Jingshu Wang, Zhenlong Yu, Dingbo Shi, Xiangsheng Xiao, Fangyun Xie, Wenlin Huang, Wuguo Deng

Published Nov 27, 2015 · Vol. 7, No. 3 · pp. 2985-3001

Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma Research Paper

Vishnu C. Ramani, Fenghuang Zhan, Jianbo He, Paola Barbieri, Alessandro Noseda, Guido Tricot, Ralph D. Sanderson

Published Nov 27, 2015 · Vol. 7, No. 2 · pp. 1598-1607

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs Research Paper

Vanesa Nogales, William C. Reinhold, Sudhir Varma, Anna Martinez-Cardus, Catia Moutinho, Sebastian Moran, Holger Heyn, Ana Sebio, Agusti Barnadas, Yves Pommier, Manel Esteller

Published Nov 27, 2015 · Vol. 7, No. 3 · pp. 3084-3097

Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancer Research Paper

Zhu-lin Luo, Hui-jun Luo, Chen Fang, Long Cheng, Zhu Huang, Ruiwu Dai, Kun Li, Fu-zhou Tian, Tao Wang, Li-jun Tang

Published Nov 26, 2015 · Vol. 7, No. 2 · pp. 1477-1485

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Namrata Rastogi, Shivali Duggal, Shailendra Kumar Singh, Konica Porwal, Vikas Kumar Srivastava, Rakesh Maurya, Madan L.B. Bhatt, Durga Prasad Mishra

Published Nov 25, 2015 · Vol. 6, No. 41 · pp. 43310-43325

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents Priority Research Paper

Vit Sestak, Jan Stariat, Jolana Cermanova, Eliska Potuckova, Jaroslav Chladek, Jaroslav Roh, Jan Bures, Hana Jansova, Petr Prusa, Martin Sterba, Stanislav Micuda, Tomas Simunek, Danuta S. Kalinowski, Des R. Richardson, Petra Kovarikova

Published Nov 25, 2015 · Vol. 6, No. 40 · pp. 42411-42428

Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing Research Paper

Song Wu, Zhao Yang, Rui Ye, Dan An, Chong Li, Yitian Wang, Yongqiang Wang, Yi Huang, Huan Liu, Feida Li, Luyun He, Da Sun, Yuan Yu, Qiaoling Li, Peide Huang, Meng Zhang, Xin Zhao, Tengteng Bi, Xuehan Zhuang, Liyan Zhang, Jingxiao Lu, Xiaojuan Sun, Fangjian Zhou, Chunxiao Liu, Guosheng Yang, Yong Hou, Zusen Fan, Zhiming Cai

Published Nov 25, 2015 · Vol. 7, No. 3 · pp. 2629-2645

Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer Priority Research Paper

Teresa Di Desidero, Ping Xu, Shan Man, Guido Bocci, Robert S. Kerbel

Published Nov 24, 2015 · Vol. 6, No. 40 · pp. 42396-42410

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer Research Paper

A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds Research Paper

ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer Research Paper

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol Research Paper

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

NF-Y activates genes of metabolic pathways altered in cancer cells Research Paper

Antihypertensive treatments in adult autosomal dominant polycystic kidney disease: network meta-analysis of the randomized controlled trials Research Paper

Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-Î²1 signaling pathway Research Paper

Antibiotic drug tigecycline inhibits melanoma progression and metastasis in a p21CIP1/Waf1-dependent manner Research Paper

Metformin suppresses hypoxia-induced stabilization of HIF-1Î± through reprogramming of oxygen metabolism in hepatocellular carcinoma Research Paper

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability Research Paper

Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy Research Paper

Melatonin inhibits AP-2Î²/hTERT, NF-ÎºB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells Research Paper

Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma Research Paper

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs Research Paper

Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancer Research Paper

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents Priority Research Paper

Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing Research Paper

Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer Research Paper

A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds Research Paper

ATR-Chk1 signaling inhibition as a therapeutic strategy to enhance cisplatin chemosensitivity in urothelial bladder cancer Research Paper

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol Research Paper

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells Research Paper

NF-Y activates genes of metabolic pathways altered in cancer cells Research Paper

Antihypertensive treatments in adult autosomal dominant polycystic kidney disease: network meta-analysis of the randomized controlled trials Research Paper

Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-Î²1 signaling pathway Research Paper

Antibiotic drug tigecycline inhibits melanoma progression and metastasis in a p21CIP1/Waf1-dependent manner Research Paper

Metformin suppresses hypoxia-induced stabilization of HIF-1Î± through reprogramming of oxygen metabolism in hepatocellular carcinoma Research Paper

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability Research Paper

Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy Research Paper

Melatonin inhibits AP-2Î²/hTERT, NF-ÎºB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells Research Paper

Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma Research Paper

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs Research Paper

Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancer Research Paper

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells Research Paper

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents Priority Research Paper

Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing Research Paper

Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer Priority Research Paper