The Oncosearch | Oncotarget

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Milica Stefanovic, Anna Tutusaus, Guillermo A. Martinez-Nieto, Cristina BÃ¡rcena, Estefania de Gregorio, Catia Moutinho, Elisabet Barbero-Camps, Alberto Villanueva, Anna Colell, Montserrat MarÃ, Carmen GarcÃa-Ruiz, Jose C. Fernandez-Checa, Albert Morales

Published Jan 22, 2016 · Vol. 7, No. 7 · pp. 8253-8267

Blocking the survival of the nastiest by HSP90 inhibition Research Perspective

Paul Workman, Paul A. Clarke, Bissan Al-Lazikani

Published Jan 21, 2016 · Vol. 7, No. 4 · pp. 3658-3661

PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells Research Paper

Winson S. Ho, Michael J. Feldman, Dragan Maric, Lauren Amable, Matthew D. Hall, Gerald M. Feldman, Abhik Ray-Chaudhury, Martin J. Lizak, Juan-Carlos Vera, R. Aaron Robison, Zhengping Zhuang, John D. Heiss

Published Jan 21, 2016 · Vol. 7, No. 11 · pp. 12447-12463

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA Research Paper

Marzia Del Re, Marcello Tiseo, Paola Bordi, Armida Dâ€™Incecco, Andrea Camerini, Iacopo Petrini, Maurizio Lucchesi, Alessandro Inno, Daniele Spada, Enrico Vasile, Valentina Citi, Giorgio Malpeli, Enrica Testa, Stefania Gori, Alfredo Falcone, Domenico Amoroso, Antonio Chella, Federico Cappuzzo, Andrea Ardizzoni, Aldo Scarpa, Romano Danesi

Published Jan 20, 2016 · Vol. 8, No. 8 · pp. 13611-13619

p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells Research Paper

Shin-Hyung Park, Myeong-A Seong, Ho-Young Lee

Published Jan 19, 2016 · Vol. 7, No. 7 · pp. 8184-8199

ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance Review

Mingxiang Ye, Xinxin Zhang, Nan Li, Yong Zhang, Pengyu Jing, Ning Chang, Jianxiong Wu, Xinling Ren, Jian Zhang

Published Jan 18, 2016 · Vol. 7, No. 11 · pp. 12289-12304

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells Research Paper

Maria Goulielmaki, Evangelos Koustas, Eirini Moysidou, Margarita Vlassi, Takehiko Sasazuki, Senji Shirasawa, George Zografos, Eftychia Oikonomou, Alexander Pintzas

Published Jan 18, 2016 · Vol. 7, No. 8 · pp. 9188-9221

The second European interdisciplinary Ewing sarcoma research summit â€“ A joint effort to deconstructing the multiple layers of a complex disease Review

Heinrich Kovar, James Amatruda, Erika Brunet, Stefan Burdach, Florencia Cidre-Aranaz, Enrique de Alava, Uta Dirksen, Wietske van der Ent, Patrick Grohar, Thomas G. P. GrÃ¼newald, Lee Helman, Peter Houghton, Kristiina Iljin, Eberhard Korsching, Marc Ladanyi, Elizabeth Lawlor, Stephen Lessnick, Joseph Ludwig, Paul Meltzer, Markus Metzler, Jaume Mora, Richard Moriggl, Takuro Nakamura, Theodore Papamarkou, Branka Radic Sarikas, Francoise RÃ©dini, Guenther H. S. Richter, Claudia Rossig, Keri Schadler, Beat W. SchÃ¤fer, Katia Scotlandi, Nathan C. Sheffield, Anang Shelat, Ewa Snaar-Jagalska, Poul Sorensen, Kimberly Stegmaier, Elizabeth Stewart, Alejandro Sweet-Cordero, Karoly Szuhai, Oscar M. Tirado, Franck Tirode, Jeffrey Toretsky, Kalliopi Tsafou, Aykut Ãœren, Andrei Zinovyev, Olivier Delattre

Published Jan 18, 2016 · Vol. 7, No. 8 · pp. 8613-8624

Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation Research Paper

Niloufar Safinia, Trishan Vaikunthanathan, Henrieta Fraser, Sarah Thirkell, Katie Lowe, Laura Blackmore, Gavin Whitehouse, Marc Martinez-Llordella, Wayel Jassem, Alberto Sanchez-Fueyo, Robert I. Lechler, Giovanna Lombardi

Published Jan 17, 2016 · Vol. 7, No. 7 · pp. 7563-7577

VEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedside Review

Marlous Arjaans, Carolina P. SchrÃ¶der, Sjoukje F. Oosting, Urania Dafni, JosÃ©e E. Kleibeuker, Elisabeth G.E. de Vries

Published Jan 14, 2016 · Vol. 7, No. 16 · pp. 21247-21258

DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance Research Paper

Wolfgang Gruber, Martin Hutzinger, Dominik Patrick Elmer, Thomas Parigger, Christina Sternberg, Lukasz Cegielkowski, Mirko Zaja, Johann Leban, Susanne Michel, Svetlana Hamm, Daniel Vitt, Fritz Aberger

Published Jan 13, 2016 · Vol. 7, No. 6 · pp. 7134-7148

Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells Research Paper

Xiao-Yang Dai, Lin-Han Zhuang, Dan-Dan Wang, Tian-Yi Zhou, Lin-Lin Chang, Ren-Hua Gai, Di-Feng Zhu, Bo Yang, Hong Zhu, Qiao-Jun He

Published Jan 12, 2016 · Vol. 7, No. 6 · pp. 6933-6947

DNA demethylation caused by 5-Aza-2â€™-deoxycytidine induces mitotic alterations and aneuploidy Research Paper

Giuseppe Costa, Viviana Barra, Laura Lentini, Danilo Cilluffo, Aldo Di Leonardo

Published Jan 12, 2016 · Vol. 7, No. 4 · pp. 3726-3739

Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors Research Paper

Caroline E. Nunes-Xavier, Karine Flem Karlsen, Christina Tekle, Cathrine Pedersen, Tove Ã˜yjord, Vesa Hongisto, Jahn M. Nesland, Ming Tan, Kristine Kleivi Sahlberg, Ã˜ystein Fodstad

Published Jan 12, 2016 · Vol. 7, No. 6 · pp. 6891-6901

miRNA-29a as a tumor suppressor mediates PRIMA-1^Met-induced anti-myeloma activity by targeting c-Myc Research Paper

Manujendra N. Saha, Jahangir Abdi, Yijun Yang, Hong Chang

Published Jan 11, 2016 · Vol. 7, No. 6 · pp. 7149-7160

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients Research Paper

Tatsuo Sugawara, Pascale Lejeune, Silke KÃ¶hr, Roland Neuhaus, Hortensia Faus, Kathy A. Gelato, Matthias Busemann, Arwed Cleve, Ulrich LÃ¼cking, Franz von Nussbaum, Michael Brands, Dominik Mumberg, Klaus Jung, Carsten Stephan, Bernard Haendler

Published Jan 9, 2016 · Vol. 7, No. 5 · pp. 6015-6028

Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02) Research Paper

Ji Yun Lee, Xu Qing, Wei Xiumin, Bai Yali, Sangah Chi, Sojung Hyeon Bak, Ho Yun Lee, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Eun Kyung Cho, Dong-Wan Kim, Hye Ryun Kim, Young Joo Min, Sin-Ho Jung, Keunchil Park, Mao Mao, Myung-Ju Ahn

Published Jan 9, 2016 · Vol. 7, No. 6 · pp. 6984-6993

Gene amplification during myogenic differentiation Research Paper

Ulrike Fischer, Nicole Ludwig, Abdulrahman Raslan, Carola Meier, Eckart Meese

Published Jan 8, 2016 · Vol. 7, No. 6 · pp. 6864-6877

Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1α signaling axis Research Paper

Rong Fu, Yan Chen, Xiao-Ping Wang, Teng An, Lei Tao, Yu-Xin Zhou, Yu-Jie Huang, Bao-An Chen, Zhi-Yu Li, Qi-Dong You, Qing-Long Guo, Zhao-Qiu Wu

Published Dec 30, 2015 · Vol. 7, No. 5 · pp. 5715-5727

Click chemistry, 3D-printing, and omics: the future of drug development Research Perspective

Razelle Kurzrock, David J. Stewart

Published Dec 29, 2015 · Vol. 7, No. 3 · pp. 2155-2158

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Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Blocking the survival of the nastiest by HSP90 inhibition Research Perspective

PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells Research Paper

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA Research Paper

p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells Research Paper

ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance Review

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells Research Paper

The second European interdisciplinary Ewing sarcoma research summit â€“ A joint effort to deconstructing the multiple layers of a complex disease Review

Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation Research Paper

VEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedside Review

DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance Research Paper

Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells Research Paper

DNA demethylation caused by 5-Aza-2â€™-deoxycytidine induces mitotic alterations and aneuploidy Research Paper

Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors Research Paper

miRNA-29a as a tumor suppressor mediates PRIMA-1^Met-induced anti-myeloma activity by targeting c-Myc Research Paper

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients Research Paper

Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02) Research Paper

Gene amplification during myogenic differentiation Research Paper

Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1α signaling axis Research Paper

Click chemistry, 3D-printing, and omics: the future of drug development Research Perspective

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma Research Paper

Blocking the survival of the nastiest by HSP90 inhibition Research Perspective

PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells Research Paper

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA Research Paper

p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells Research Paper

ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance Review

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells Research Paper

The second European interdisciplinary Ewing sarcoma research summit â€“ A joint effort to deconstructing the multiple layers of a complex disease Review

Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation Research Paper

VEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedside Review

DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance Research Paper

Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells Research Paper

DNA demethylation caused by 5-Aza-2â€™-deoxycytidine induces mitotic alterations and aneuploidy Research Paper

Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors Research Paper

miRNA-29a as a tumor suppressor mediates PRIMA-1Met-induced anti-myeloma activity by targeting c-Myc Research Paper

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients Research Paper

Longitudinal monitoring of EGFR mutations in plasma predicts outcomes of NSCLC patients treated with EGFR TKIs: Korean Lung Cancer Consortium (KLCC-12-02) Research Paper

Gene amplification during myogenic differentiation Research Paper

Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1α signaling axis Research Paper

Click chemistry, 3D-printing, and omics: the future of drug development Research Perspective

miRNA-29a as a tumor suppressor mediates PRIMA-1^Met-induced anti-myeloma activity by targeting c-Myc Research Paper