The Oncosearch | Oncotarget

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death Research Paper

Valeria Tosello, Valentina Saccomani, Jiyang Yu, Fulvio Bordin, Alberto Amadori, Erich Piovan

Published Jun 10, 2016 · Vol. 7, No. 29 · pp. 45715-45729

DMET^TM (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine Review

Mariamena Arbitrio, Maria Teresa Di Martino, Francesca Scionti, Giuseppe Agapito, Pietro Hiram Guzzi, Mario Cannataro, Pierfrancesco Tassone, Pierosandro Tagliaferri

Published Jun 9, 2016 · Vol. 7, No. 33 · pp. 54028-54050

Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/β-catenin signaling Research Paper

Dan Liu, Lei Du, Dong Chen, Zhongde Ye, Hongxia Duan, Tao Tu, Jing Feng, Yili Yang, Quan Chen, Xiyun Yan

Published Jun 9, 2016 · Vol. 7, No. 26 · pp. 40704-40718

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder Research Paper

Jiawei Guo, Jing Lv, Siyu Chang, Zhi Chen, Weiqiang Lu, Chuanliang Xu, Mingyao Liu, Xiufeng Pang

Published Jun 9, 2016 · Vol. 7, No. 29 · pp. 45249-45262

Cancer-secreted AGR2 induces programmed cell death in normal cells Research Paper

Elizabeth A. Vitello, Sue-Ing Quek, Heather Kincaid, Thomas Fuchs, Daniel J. Crichton, Pamela Troisch, Alvin Y. Liu

Published Jun 8, 2016 · Vol. 7, No. 31 · pp. 49425-49434

Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis Research Paper

Chien-Ju Lin, Yi-Ling Lin, Frank Luh, Yun Yen, Ruei-Ming Chen

Published Jun 7, 2016 · Vol. 7, No. 27 · pp. 42408-42421

Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells Research Paper

Sophie Bustany, JÃ©rÃ´me Bourgeais, Guergana Tchakarska, Simon Body, Olivier HÃ©rault, Fabrice Gouilleux, Brigitte Sola

Published Jun 7, 2016 · Vol. 7, No. 29 · pp. 45214-45224

PA-MSHA in combination with EGFR tyrosine kinase inhibitor: A new strategy to overcome the drug resistance of non-small cell lung cancer cells Research Paper

Xin-min Zhao, Shi-yun Pan, Qi-ling Huang, You-ni Lu, Xiang-hua Wu, Jian-Hua Chang, Zhe-Bin Liu, Xu-Wei Cai, Qi Liu, Jia-lei Wang, Xiao-Long Fu

Published Jun 7, 2016 · Vol. 7, No. 31 · pp. 49384-49396

PNT2258, a novel deoxyribonucleic acid inhibitor, induces cell cycle arrest and apoptosis via a distinct mechanism of action: a new class of drug for non-Hodgkin's lymphoma Research Paper

Abdul Shukkur Ebrahim, Mustapha Kandouz, Allison Liddane, Hussam Sabbagh, Yuning Hou, Chunying Li, Ayad Al-Katib

Published Jun 7, 2016 · Vol. 7, No. 27 · pp. 42374-42384

Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways Research Paper

Subburayan Karthikeyan, Sugeerappa Laxmanappa Hoti, Yasin Nazeer, Harsha Vasudev Hegde

Published Jun 7, 2016 · Vol. 7, No. 27 · pp. 42353-42373

Multi-targeting NGR-modified liposomes recognizing glioma tumor cells and vasculogenic mimicry for improving anti-glioma therapy Research Paper

Dan Huang, Shuang Zhang, Ting Zhong, Wei Ren, Xin Yao, Yang Guo, Xiao-Chuan Duan, Yi-Fan Yin, Shu-Shi Zhang, Xuan Zhang

Published Jun 7, 2016 · Vol. 7, No. 28 · pp. 43616-43628

Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer Research Paper

Samer Alzoubi, Leigh Brody, Sunniyat Rahman, Anne-Laure Mahul-Mellier, Nicolas Mercado, Kazuhiro Ito, Mona El-Bahrawy, Andrew Silver, Alan Boobis, Jimmy D. Bell, Nabil Hajji

Published Jun 7, 2016 · Vol. 7, No. 28 · pp. 44505-44521

Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma Research Paper

Hsiao-Yun Chen, Liang-Ting Lin, Mong-Lien Wang, Shu-Hsien Lee, Ming-Long Tsai, Chi-Chang Tsai, Wei-Hsiu Liu, Tzu-Chien Chen, Yi-Ping Yang, Yi-Yen Lee, Yuh-Lih Chang, Pin-I Huang, Yi-Wei Chen, Wen-Liang Lo, Shih-Hwa Chiou, Ming-Teh Chen

Published Jun 7, 2016 · Vol. 7, No. 27 · pp. 42485-42501

WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck Research Paper

Vassiliki Saloura, Theodore Vougiouklakis, Makda Zewde, Kazuma Kiyotani, Jae-Hyun Park, Guimin Gao, Theodore Karrison, Mark Lingen, Yusuke Nakamura, Ryuji Hamamoto

Published Jun 7, 2016 · Vol. 7, No. 27 · pp. 42527-42538

Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis Research Paper

Sudeshna Goswami, Neelam Sharma-Walia

Published Jun 6, 2016 · Vol. 7, No. 37 · pp. 58953-58974

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer Research Paper

Lichao Sun, Joseph Burnett, Mari Gasparyan, Fangying Xu, Hui Jiang, Chang-Ching Lin, Ila Myers, Hasan Korkaya, Yajing Liu, Jamie Connarn, Huining He, Ning Zhang, Max S. Wicha, Duxin Sun

Published Jun 6, 2016 · Vol. 7, No. 32 · pp. 51408-51422

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport Research Paper

Juliana Velez, Rongqing Pan, Jason T.C. Lee, Leonardo Enciso, Marta Suarez, Jorge Eduardo Duque, Daniel Jaramillo, Catalina Lopez, Ludis Morales, William Bornmann, Marina Konopleva, Gerald Krystal, Michael Andreeff, Ismael Samudio

Published Jun 6, 2016 · Vol. 7, No. 32 · pp. 51435-51449

HIF2Î±/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy Research Paper

Ji-Hye Kwak, Na-Hee Lee, Hwa-Yong Lee, In-Sun Hong, Jeong-Seok Nam

Published Jun 6, 2016 · Vol. 7, No. 28 · pp. 43518-43533

Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma Research Paper

Askar Obulkasim, Bauke Ylstra, Hendrik F. van Essen, Christian Benner, Sally Stenning, Ruth Langley, William Allum, David Cunningham, Imran Inam, Lindsay C. Hewitt, Nicolas P. West, Gerrit A. Meijer, Mark A. van de Wiel, Heike I. Grabsch

Published Jun 6, 2016 · Vol. 7, No. 28 · pp. 44084-44095

Targeting microenvironment in cancer therapeutics Review

Matthew Martin, Han Wei, Tao Lu

Published Jun 5, 2016 · Vol. 7, No. 32 · pp. 52575-52583

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Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death Research Paper

DMET^TM (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine Review

Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/β-catenin signaling Research Paper

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder Research Paper

Cancer-secreted AGR2 induces programmed cell death in normal cells Research Paper

Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis Research Paper

Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells Research Paper

PA-MSHA in combination with EGFR tyrosine kinase inhibitor: A new strategy to overcome the drug resistance of non-small cell lung cancer cells Research Paper

PNT2258, a novel deoxyribonucleic acid inhibitor, induces cell cycle arrest and apoptosis via a distinct mechanism of action: a new class of drug for non-Hodgkin's lymphoma Research Paper

Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways Research Paper

Multi-targeting NGR-modified liposomes recognizing glioma tumor cells and vasculogenic mimicry for improving anti-glioma therapy Research Paper

Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer Research Paper

Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma Research Paper

WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck Research Paper

Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis Research Paper

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer Research Paper

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport Research Paper

HIF2Î±/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy Research Paper

Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma Research Paper

Targeting microenvironment in cancer therapeutics Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death Research Paper

DMETTM (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine Review

Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/β-catenin signaling Research Paper

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder Research Paper

Cancer-secreted AGR2 induces programmed cell death in normal cells Research Paper

Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis Research Paper

Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells Research Paper

PA-MSHA in combination with EGFR tyrosine kinase inhibitor: A new strategy to overcome the drug resistance of non-small cell lung cancer cells Research Paper

PNT2258, a novel deoxyribonucleic acid inhibitor, induces cell cycle arrest and apoptosis via a distinct mechanism of action: a new class of drug for non-Hodgkin's lymphoma Research Paper

Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways Research Paper

Multi-targeting NGR-modified liposomes recognizing glioma tumor cells and vasculogenic mimicry for improving anti-glioma therapy Research Paper

Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer Research Paper

Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma Research Paper

WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck Research Paper

Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis Research Paper

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer Research Paper

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport Research Paper

HIF2Î±/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy Research Paper

Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma Research Paper

Targeting microenvironment in cancer therapeutics Review

DMET^TM (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine Review