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The mutational profile and infiltration pattern of murine MLH1^-/- tumors: concurrences, disparities and cell line establishment for functional analysis Research Paper

Claudia Maletzki, Franziska Beyrich, Maja HÃ¼hns, Ernst Klar, Michael Linnebacher

Published Jul 18, 2016 · Vol. 7, No. 33 · pp. 53583-53598

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrettâ€™s-like esophagus Research Paper

Yoomi Lee, Aleksandra M. Urbanska, Yoku Hayakawa, Hongshan Wang, Andrew S. Au, Aesis M. Luna, Wenju Chang, Guangchun Jin, Govind Bhagat, Julian A. Abrams, Richard A. Friedman, Andrea Varro, Kenneth K. Wang, Malcolm Boyce, Anil K. Rustgi, Antonia R. Sepulveda, Michael Quante, Timothy C. Wang

Published Jul 18, 2016 · Vol. 8, No. 1 · pp. 203-214

The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma Research Paper

Faqing Tian, Chunyan Wang, Meiqin Tang, Juheng Li, Xiaohui Cheng, Sihan Zhang, Delan Ji, Yingcai Huang, Huiqing Li

Published Jul 16, 2016 · Vol. 7, No. 32 · pp. 51934-51942

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer Research Paper

Callie R. Merry, Sarah McMahon, Megan E. Forrest, Cynthia F. Bartels, Alina Saiakhova, Courtney A. Bartel, Peter C. Scacheri, Cheryl L. Thompson, Mark W. Jackson, Lyndsay N. Harris, Ahmad M. Khalil

Published Jul 16, 2016 · Vol. 7, No. 33 · pp. 53230-53244

Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer Research Paper

Robin M. Hallett, Adele Girgis-Gabardo, William D. Gwynne, Andrew O. Giacomelli, Jennifer N.P. Bisson, Jeremy E. Jensen, Anna Dvorkin-Gheva, John A. Hassell

Published Jul 15, 2016 · Vol. 7, No. 33 · pp. 53137-53152

Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties Research Paper

Alexander A. Chumanevich, Erin E. Witalison, Anusha Chaparala, Anastasiya Chumanevich, Prakash Nagarkatti, Mitzi Nagarkatti, Lorne J. Hofseth

Published Jul 14, 2016 · Vol. 7, No. 33 · pp. 52928-52939

Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics Research Paper

Kaikai Shen, Fangfang Lu, Jianling Xie, Minfeng Wu, Bo Cai, Yurong Liu, Hong Zhang, Hongsheng Tan, Yingyi Pan, Hongxi Xu

Published Jul 13, 2016 · Vol. 7, No. 31 · pp. 50596-50611

An appraisal of drug development timelines in the Era of precision oncology Research Paper

Denis Leonardo Jardim, Maria Schwaederle, David S. Hong, Razelle Kurzrock

Published Jul 13, 2016 · Vol. 7, No. 33 · pp. 53037-53046

Bioinformatics facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy Research Paper

Yana Lv, Yumei Que, Qiao Su, Qiang Li, Xi Chen, Haitao Lu

Published Jul 13, 2016 · Vol. 7, No. 32 · pp. 52270-52280

Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors Priority Research Paper

Lynsey Vaughan, Paul A. Clarke, Karen Barker, Yvan Chanthery, Clay W. Gustafson, Elizabeth Tucker, Jane Renshaw, Florence Raynaud, Xiaodun Li, Rosemary Burke, Yann Jamin, Simon P. Robinson, Andrew Pearson, Michel Maira, William A. Weiss, Paul Workman, Louis Chesler

Published Jul 12, 2016 · Vol. 7, No. 36 · pp. 57525-57544

Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion Research Paper

Nakho Chang, Hye Won Lee, Joung Eun Lim, Da Eun Jeong, Hye Jin Song, Sudong Kim, Do-Hyun Nam, Hyun Hwan Sung, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han-Yong Choi, Hwang Gyun Jeon

Published Jul 12, 2016 · Vol. 7, No. 32 · pp. 51626-51639

Ranking novel cancer driving synthetic lethal gene pairs using TCGA data Research Paper

Hao Ye, Xiuhua Zhang, Yunqin Chen, Qi Liu, Jia Wei

Published Jul 11, 2016 · Vol. 7, No. 34 · pp. 55352-55367

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

Lara Paracchini, Laura Mannarino, Ilaria Craparotta, Chiara Romualdi, Robert Fruscio, Tommaso Grassi, Vittoria Fotia, Giulia Caratti, Patrizia Perego, Enrica Calura, Luca Clivio, Maurizio D’Incalci, Luca Beltrame, Sergio Marchini

Published Jul 9, 2016 · Vol. 12, No. 24 · pp. 2404-2417

Keywords: ovarian cancer, temporal heterogeneity, spatial heterogeneity, targeted next generation sequencing, drug resistance

The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer Research Paper

Umar Raza, Ã–zge Saatci, Stefan Uhlmann, Suhail A Ansari, Erol EyÃ¼poÄŸlu, Emre Yurdusev, Merve Mutlu, Pelin GÃ¼lizar Ersan, Mustafa Kadri AltundaÄŸ, Jitao David Zhang, Hayriye TatlÄ± DoÄŸan, GÃ¼lnur GÃ¼ler, Ã–zgÃ¼r Åžahin

Published Jul 8, 2016 · Vol. 7, No. 31 · pp. 49859-49877

Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity Research Paper

Hai-Tao Su, Xin Li, De-Sheng Liang, Xian-Rong Qi

Published Jul 8, 2016 · Vol. 7, No. 32 · pp. 51535-51552

Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization Research Paper

Hao Wang, Cheng Huang, Liang Zhao, Huan Zhang, Jing Mo Yang, Peng Luo, Bing-Xiang Zhan, Qing Pan, Jun Li, Bao-Long Wang

Published Jul 8, 2016 · Vol. 7, No. 31 · pp. 49848-49858

Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature Research Paper

Sheng Guo, Dawei Chen, Xuesong Huang, Jie Cai, Jean-Pierre Wery, Qi-Xiang Li

Published Jul 8, 2016 · Vol. 7, No. 31 · pp. 50575-50581

Nuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpression Research Paper

Wen-Shu Chen, Liang-Chih Liu, Chia-Jui Yen, Yun-Ju Chen, Jhen-Yu Chen, Chien-Yi Ho, Shu-Hui Liu, Ching-Chow Chen, Wei-Chien Huang

Published Jul 7, 2016 · Vol. 7, No. 35 · pp. 56309-56323

Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study Research Paper

Daniela Gaglio, Silvia Valtorta, Marilena Ripamonti, Marcella Bonanomi, Chiara Damiani, Sergio Todde, Alfredo Simone Negri, Francesca Sanvito, Fabrizia Mastroianni, Antonella Di Campli, Gabriele Turacchio, Giuseppe Di Grigoli, Sara Belloli, Alberto Luini, Maria Carla Gilardi, Anna Maria Colangelo, Lilia Alberghina, Rosa Maria Moresco

Published Jul 7, 2016 · Vol. 7, No. 32 · pp. 52017-52031

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2 Research Paper

Lin Zhou, Xin Liang, Lingling Zhang, Liyan Yang, Norio Nagao, Hongkun Wu, Chang Liu, Shengchao Lin, Guoxiang Cai, Jianwen Liu

Published Jul 7, 2016 · Vol. 7, No. 32 · pp. 51943-51954

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The mutational profile and infiltration pattern of murine MLH1^-/- tumors: concurrences, disparities and cell line establishment for functional analysis Research Paper

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrettâ€™s-like esophagus Research Paper

The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma Research Paper

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer Research Paper

Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer Research Paper

Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties Research Paper

Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics Research Paper

An appraisal of drug development timelines in the Era of precision oncology Research Paper

Bioinformatics facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy Research Paper

Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors Priority Research Paper

Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion Research Paper

Ranking novel cancer driving synthetic lethal gene pairs using TCGA data Research Paper

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer Research Paper

Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity Research Paper

Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization Research Paper

Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature Research Paper

Nuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpression Research Paper

Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study Research Paper

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The mutational profile and infiltration pattern of murine MLH1-/- tumors: concurrences, disparities and cell line establishment for functional analysis Research Paper

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrettâ€™s-like esophagus Research Paper

The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma Research Paper

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer Research Paper

Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer Research Paper

Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties Research Paper

Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics Research Paper

An appraisal of drug development timelines in the Era of precision oncology Research Paper

Bioinformatics facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy Research Paper

Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors Priority Research Paper

Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion Research Paper

Ranking novel cancer driving synthetic lethal gene pairs using TCGA data Research Paper

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies Research Paper

The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer Research Paper

Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity Research Paper

Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization Research Paper

Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature Research Paper

Nuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpression Research Paper

Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study Research Paper

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2 Research Paper

The mutational profile and infiltration pattern of murine MLH1^-/- tumors: concurrences, disparities and cell line establishment for functional analysis Research Paper