The Oncosearch | Oncotarget

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Angeliki Andrikopoulou, Evangelos Terpos, Spyridoula Chatzinikolaou, Kleoniki Apostolidou, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Meletios-Athanasios Dimopoulos, Flora Zagouri

Published Sep 2, 2021 · Vol. 12, No. 21 · pp. 2206-2214

Keywords: TP53 mutations, next-generation sequencing, biomarker, prognosis, breast cancer

Association of four genetic variants with colorectal cancer in Kazakhstan population Research Paper

Yevgeniya Kolesnikova, Dmitriy Babenko, Irina Kadyrova, Svetlana Kolesnichenko, Lyudmila Akhmaltdinova, Ilya Korshukov, Naylya Kabildina, Valentina Sirota, Vera Zhumaliyeva, Dana Taizhanova, Dmitriy Vazenmiller, Anar Turmukhambetova

Published Sep 2, 2021 · Vol. 12, No. 21 · pp. 2215-2222

Keywords: colorectal adenocarcinoma, rs10795668, rs1035209, rs11190164, rs10506868

Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma Research Paper

Kelsey Maddison, Moira C. Graves, Nikola A. Bowden, Michael Fay, Ricardo E. Vilain, Sam Faulkner, Paul A. Tooney

Published Sep 1, 2021 · Vol. 12, No. 21 · pp. 2177-2187

Keywords: glioblastoma, tumour-infiltrating lymphocytes, programmed cell death 1, tumour recurrence, immune microenvironment

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa, Sônia Nair Báo

Published Aug 27, 2021 · Vol. 12, No. 19 · pp. 1920-1936

Keywords: KIF11 inhibition, Kinesin Eg5, breast cancer, adjuvant treatment, cancer progression

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trupti Vardam-Kaur, Latha B. Pathangey, Daniel J. McCormick, P. Leif Bergsagel, Peter A. Cohen, Sandra J. Gendler

Published Aug 27, 2021 · Vol. 12, No. 20 · pp. 2051-2067

Keywords: multiple myeloma, cellular therapy, CD4/CD8 T cells, peptides, immunotherapy

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Sayantani Chatterjee, Julian Ugonotti, Ling Y. Lee, Arun Everest-Dass, Rebeca Kawahara, Morten Thaysen-Andersen

Published Aug 24, 2021 · Vol. 12, No. 21 · pp. 2188-2205

Keywords: oligomannose, α1,2-mannosidase, cancer, glycomics, mass spectrometry

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Adam S. Kittai, Olga V. Danilova, Vi Lam, Tingting Liu, Nur Bruss, Scott Best, Guang Fan, Alexey V. Danilov

Published Aug 23, 2021 · Vol. 12, No. 20 · pp. 2068-2074

Keywords: pevonedistat, T-cell lymphoma, chromosomal instability, anaphase catastrophe

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Marcel Kemper, Georg Evers, Arik Bernard Schulze, Jan Sperveslage, Christoph Schülke, Georg Lenz, Thomas Herold, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Annalen Bleckmann

Published Aug 23, 2021 · Vol. 12, No. 19 · pp. 1946-1952

Keywords: NSCLC, resistance mutations, ALK, KRAS, ALK inhibitors

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Brenna M. Zimmer, Michelle E. Howell, Linlin Ma, Jeffrey R. Enders, Danielle Lehman, Eva Corey, Joseph J. Barycki, Melanie A. Simpson

Published Aug 19, 2021 · Vol. 12, No. 19 · pp. 1886-1902

Keywords: prostate cancer, castration resistance, detoxification, UDP-glucose dehydrogenase, patient-derived xenografts

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Zachary R. Wakefield, Mai Tanaka, Christine Pampo, Sharon Lepler, Lori Rice, Joy Guingab-Cagmat, Timothy J. Garrett, Dietmar W. Siemann

Published Aug 18, 2021 · Vol. 12, No. 18 · pp. 1737-1748

Keywords: aerobic exercise, breast cancer, hypoxia, doxorubicin, cardiotoxicity

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

Ingrid Dubois-Vedrenne, Diana Al Delbany, Olivier De Henau, Virginie Robert, Maxime Vernimmen, Francina Langa, Anne Lefort, Frédérick Libert, Valérie Wittamer, Marc Parmentier

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1903-1919

Keywords: chemerin, ChemR23, CMKLR1, Rarres2, tumor angiogenesis

High expression of Myosin 1g in pediatric acute lymphoblastic leukemia Research Paper

Laura A. Estrada-Abreo, Leonor Rodríguez-Cruz, Yanelly Garfias-Gómez, Janeth E. Araujo-Cardenas, Gabriela Antonio-Andrés, Alfonso R. Salgado-Aguayo, Darío Orozco-Ruiz, José Refugio Torres-Nava, Juan D. Díaz-Valencia, Sara Huerta-Yépez, Genaro Patiño-López

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1937-1945

Keywords: Myosin 1g, acute lymphoblastic leukemia, high risk, biomarker, pediatric

Old drug, new trick: proton pump inhibitors find new purpose in cancer care News

Natalie A. Ridge, Mohit Shiv Agarwal, Mohamad Hassan Fakhreddine

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1861-1862

Keywords: radiosensitizer, proton pump inhibitor, esomeprazole, radioresistance, radiotherapy

Correction: HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer Correction

Teru Hideshima, Ralph Mazitschek, Jun Qi, Naoya Mimura, Jen-Chieh Tseng, Andrew L. Kung, James E. Bradner, Kenneth C. Anderson

Published Aug 14, 2021 · Vol. 12, No. 17 · pp. 1736-1736

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Zhiguang Xiao, Bianca Sperl, Silvia Gärtner, Tatiana Nedelko, Elvira Stacher-Priehse, Axel Ullrich, Pjotr G. Knyazev

Published Aug 14, 2021 · Vol. 12, No. 17 · pp. 1734-1735

Anti-aging: senolytics or gerostatics (unconventional view) Review

Mikhail V. Blagosklonny

Published Aug 12, 2021 · Vol. 12, No. 18 · pp. 1821-1835

Keywords: geroscience, senolytics, hyperfunction theory, aging, sirolimus

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Hélène Marijon, Sigal Gery, Hua Chang, Yosef Landesman, Sharon Shacham, Dhong Hyun Lee, Aimery de Gramont, Harold Phillip Koeffler

Published Aug 10, 2021 · Vol. 12, No. 18 · pp. 1749-1762

Keywords: selinexor, XPO1, olaparib, triple negative breast cancer, BRCA1

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Case Report

Kevin Drenner, Gargi D. Basu, Laurie J. Goodman, Audrey A. Ozols, Janine R. LoBello, Thomas Royce, Michael S. Gordon, Erkut H. Borazanci, Margaux A. Steinbach, Jeffrey Trent, Sunil Sharma

Published Aug 6, 2021 · Vol. 12, No. 18 · pp. 1836-1847

Keywords: whole exome sequencing, RNA sequencing, precision medicine, rare mutations, genomic alteration

Correlation between PD-L1 expression and MET gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver Research Paper

Marta Domènech, Ana M. Muñoz Marmol, Jose Luis Mate, Anna Estival, Teresa Moran, Marc Cucurull, Maria Saigi, Ainhoa Hernandez, Carolina Sanz, Alba Hernandez-Gallego, Aintzane Urbizu, Anna Martinez-Cardus, Adrià Bernat, Enric Carcereny

Published Aug 5, 2021 · Vol. 12, No. 18 · pp. 1802-1810

Keywords: non-small cell lung cancer, oncogenic driver, PD-L1, MET amplification, smoking habit

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TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Association of four genetic variants with colorectal cancer in Kazakhstan population Research Paper

Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

High expression of Myosin 1g in pediatric acute lymphoblastic leukemia Research Paper

Old drug, new trick: proton pump inhibitors find new purpose in cancer care News

Correction: HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer Correction

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Anti-aging: senolytics or gerostatics (unconventional view) Review

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Case Report

Correlation between PD-L1 expression and MET gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

TP53 mutations determined by targeted NGS in breast cancer: a case-control study Research Paper

Association of four genetic variants with colorectal cancer in Kazakhstan population Research Paper

Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis Research Paper

High expression of Myosin 1g in pediatric acute lymphoblastic leukemia Research Paper

Old drug, new trick: proton pump inhibitors find new purpose in cancer care News

Correction: HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer Correction

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Anti-aging: senolytics or gerostatics (unconventional view) Review

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Case Report

Correlation between PD-L1 expression and MET gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper