The Oncosearch | Oncotarget

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Ignacio Durán, Daniel Castellano, Javier Puente, Lidia Martín-Couce, Esther Bello, Urbano Anido, José Manuel Mas, Luis Costa

Published Jan 20, 2022 · Vol. 13, No. 1 · pp. 237-256

Keywords: machine learning, cabozantinib, renal cell carcinoma, tumour microenvironment, systems biology

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial Research Paper

Mauro Rogério de Barros Wanderley Jr., Mônica Samuel Ávila, Miguel Morita Fernandes-Silva, Fátima das Dores Cruz, Sara Michelly Gonçalves Brandão, Vagner Oliveira Carvalho Rigaud, Ludhmila Abrahão Hajjar, Roberto Kalil Filho, Edécio Cunha-Neto, Edimar Alcides Bocchi, Silvia Moreira Ayub-Ferreira

Published Jan 20, 2022 · Vol. 13, No. 1 · pp. 214-223

Keywords: cardiotoxicity, biomarkers, myeloperoxidase, galectin-3, anthracyclines

Antitumor effect of isoquercetin on tissue vasohibin expression and colon cancer vasculature Research Paper

Daniel de Castilho da Silva, Guilherme Di Camillo Orfali, Maycon Giovani Santana, Jessica Kaoru Yamamoto Palma, Isabella Ramos de Oliveira Assunção, Isadora Moraes Marchesi, Ana Yoshie Kitagawa Grizotto, Natália Peres Martinez, Simone Felliti, José Aires Pereira, Denise Gonçalves Priolli

Published Jan 19, 2022 · Vol. 13, No. 1 · pp. 307-318

Keywords: target, angiogenic proteins, neoplasms, flavonols, antitumor assays-xenograft model

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Sydney Weber Boutros, Destine Krenik, Sarah Holden, Vivek K. Unni, Jacob Raber

Published Jan 14, 2022 · Vol. 13, No. 1 · pp. 198-213

Keywords: amifostine, etoposide, double strand breaks, memory, sex

Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications Research Paper

Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Yuki Uchida, Ryoji Hyakudomi, Tetsu Yamamoto, Kiyoe Takai, Yohei Sasaki, Koki Kawakami, Yoshitsugu Tajima

Published Jan 11, 2022 · Vol. 13, No. 1 · pp. 183-197

Keywords: gastric cancer, prognostic nutritional index, laparoscopic gastrectomy, postoperative complications, prognosis

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Research Paper

Connor Willis, Hillevi Bauer, Trang H. Au, Jyothi Menon, Sudhir Unni, Dao Tran, Zachary Rivers, Wallace Akerley, Matthew B. Schabath, Firas Badin, Ashley Sekhon, Malini Patel, Bing Xia, Beth Gustafson, John L. Villano, John-Michael Thomas, Solomon J. Lubinga, Michael A. Cantrell, Diana Brixner, David Stenehjem

Published Jan 7, 2022 · Vol. 13, No. 1 · pp. 257-270

Keywords: lung neoplasma, tumor biomarkers, immunotherapy

GZ17-6.02 and palbociclib interact to kill ER+ breast cancer cells Research Paper

Laurence Booth, Cameron West, Robert P. Moore, Daniel Von Hoff, Paul Dent

Published Jan 6, 2022 · Vol. 13, No. 1 · pp. 92-104

Keywords: GZ17-6.02, palbociclib, 5FU, autophagy, breast cancer

Seventh BHD international symposium: recent scientific and clinical advancement Meeting Report

Mark R. Woodford, Avgi Andreou, Masaya Baba, Irma van de Beek, Chiara Di Malta, Iris Glykofridis, Hannah Grimes, Elizabeth P. Henske, Othon Iliopoulos, Masatoshi Kurihara, Romain Lazor, W. Marston Linehan, Kenki Matsumoto, Stefan J. Marciniak, Yukiko Namba, Arnim Pause, Neil Rajan, Anindita Ray, Laura S. Schmidt, Wei Shi, Ortrud K. Steinlein, Julia Thierauf, Roberto Zoncu, Anna Webb, Mehdi Mollapour

Published Dec 30, 2021 · Vol. 13, No. 1 · pp. 173-181

Keywords: Birt-Hogg-Dubé syndrome, folliculin, FLCN, tuberous sclerosis complex, LDHA

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer Research Paper

Tolulope Tosin Adeyelu, Aurelio A. Moya-Garcia, Christine Orengo

Published Dec 28, 2021 · Vol. 13, No. 1 · pp. 105-117

Keywords: CATH-FunFams, bladder cancer, protein interaction network, drug targets, drug side effects

Anaplastic lymphoma kinase rearrangement prevalence in patients with advanced non-small cell lung cancer in the United States: retrospective real world data Research Paper

Timothy Craig Allen, Yan Xiao, Baiyu Yang, Denise Croix, Anup Abraham, Stella Redpath, Julia Engstrom-Melynk, Roma Shah, Jaya Madala, Eric H. Bernicker

Published Dec 23, 2021

Keywords: ALK rearrangement, NSCLC, prevalence

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Nkune Williams Nkune, Cherie Ann Kruger, Heidi Abrahamse

Published Dec 23, 2021 · Vol. 13, No. 1 · pp. 156-172

Keywords: cannabidiol, photodynamic therapy, colorectal cancer, nanoparticles, photosensitizer

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer Research Paper

Ruiko Ogata, Shiori Mori, Hitoshi Ohmori, Shingo Kishi, Rina Fujiwara-Tani, Takamitsu Sasaki, Yukiko Nishiguchi, Chie Nakashima, Kei Goto, Isao Kawahara, Yi Luo, Hiroki Kuniyasu

Published Dec 23, 2021 · Vol. 13, No. 1 · pp. 122-135

Keywords: linoleic acid, stemness, GLI2, ubiquitination, colorectal cancer

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells Research Paper

Austin McDermott, KyoungHyun Kim, Susan Kasper, Shuk-Mei Ho, Yuet-Kin Leung

Published Dec 23, 2021 · Vol. 13, No. 1 · pp. 46-60

Keywords: GPR30, castration resistant, promoter, GPER1 spliced variants, transcription start site

Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma Research Paper

Rachael A. Clark, Jingbo Qiao, Jillian C. Jacobson, Dai H. Chung

Published Dec 22, 2021 · Vol. 13, No. 1 · pp. 32-45

Keywords: neuroblastoma, serine hydroxymethyltransferase 2 (SHMT2), tumorigenesis, serine metabolism, one-carbon metabolism

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype Research Paper

Elham Khosrowabadi, Tomasz Wenta, Salla Keskitalo, Aki Manninen, Sakari Kellokumpu

Published Dec 22, 2021 · Vol. 13, No. 1 · pp. 73-89

Keywords: cancer, invasion, glycosylation, glycocode, terminal GalNAc, Helix Pomatia agglutinin (HPA)

Oxygen-independent, CDK4/CDK6-dependent degradation of hypoxia-inducible factor-1α takes cancers’ breath away Commentary

Len Neckers

Published Dec 22, 2021 · Vol. 13, No. 1 · pp. 16-17

Keywords: hypoxia, HIF-1α degradation, cyclin dependent kinases, Smurf2, Hsp90

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Jodi I. Rattner, Karen A. Kopciuk, Hans J. Vogel, Patricia A. Tang, Jeremy D. Shapiro, Dongsheng Tu, Derek J. Jonker, Lillian L. Siu, Chris J. O’Callaghan, Oliver F. Bathe

Published Dec 21, 2021 · Vol. 13, No. 1 · pp. 61-72

Keywords: colorectal cancer, metabolomics, response biomarkers, radiographic imaging, chemotherapy

Redefining and expanding the sphere of influence of BRCA in breast and colorectal cancers and beyond Commentary

Emil Lou

Published Dec 20, 2021 · Vol. 13, No. 1 · pp. 120-121

Keywords: BRCA1, BRCA2, BRCA, cancer genetics, breast cancer

TEST: Please ignore this paper: Anaplastic lymphoma kinase rearrangement prevalence in patients with advanced non-small cell lung cancer in the United States: retrospective real world data Research Paper

Timothy Craig Allen, Yan Xiao, Baiyu Yang, Denise Croix, Anup Abraham, Stella Redpath, Julia Engstrom-Melynk, Roma Shah, Jaya Madala, Eric H. Bernicker

Published Dec 17, 2021

Keywords: ALK rearrangement, NSCLC, prevalence

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

Lindsay R. Stolzenburg, Barrett Ainsworth, Bridget Riley-Gillis, Tibor Pakozdi, Areej Ammar, Paul A. Ellis, Julie L. Wilsbacher, Cyril Y. Ramathal

Published Dec 17, 2021 · Vol. 13, No. 1 · pp. 1-12

Keywords: PARP inhibitor, veliparib, cisplatin, transcriptomics, NSCLC

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Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial Research Paper

Antitumor effect of isoquercetin on tissue vasohibin expression and colon cancer vasculature Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications Research Paper

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Research Paper

GZ17-6.02 and palbociclib interact to kill ER+ breast cancer cells Research Paper

Seventh BHD international symposium: recent scientific and clinical advancement Meeting Report

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer Research Paper

Anaplastic lymphoma kinase rearrangement prevalence in patients with advanced non-small cell lung cancer in the United States: retrospective real world data Research Paper

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer Research Paper

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells Research Paper

Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma Research Paper

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype Research Paper

Oxygen-independent, CDK4/CDK6-dependent degradation of hypoxia-inducible factor-1α takes cancers’ breath away Commentary

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Redefining and expanding the sphere of influence of BRCA in breast and colorectal cancers and beyond Commentary

TEST: Please ignore this paper: Anaplastic lymphoma kinase rearrangement prevalence in patients with advanced non-small cell lung cancer in the United States: retrospective real world data Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial Research Paper

Antitumor effect of isoquercetin on tissue vasohibin expression and colon cancer vasculature Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications Research Paper

Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Research Paper

GZ17-6.02 and palbociclib interact to kill ER+ breast cancer cells Research Paper

Seventh BHD international symposium: recent scientific and clinical advancement Meeting Report

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer Research Paper

Anaplastic lymphoma kinase rearrangement prevalence in patients with advanced non-small cell lung cancer in the United States: retrospective real world data Research Paper

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer Research Paper

The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells Research Paper

Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma Research Paper

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype Research Paper

Oxygen-independent, CDK4/CDK6-dependent degradation of hypoxia-inducible factor-1α takes cancers’ breath away Commentary

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Redefining and expanding the sphere of influence of BRCA in breast and colorectal cancers and beyond Commentary

TEST: Please ignore this paper: Anaplastic lymphoma kinase rearrangement prevalence in patients with advanced non-small cell lung cancer in the United States: retrospective real world data Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper