The Oncosearch | Oncotarget

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Nikolai Petrov, Hee-Sheung Lee, Mikhail Liskovykh, Marie-Paule Teulade-Fichou, Hiroshi Masumoto, William C. Earnshaw, Yves Pommier, Vladimir Larionov, Natalay Kouprina

Published Jun 27, 2021 · Vol. 12, No. 15 · pp. 1444-1456

Keywords: chromosome instability, CIN, platinum-derived G4-quadruplexes, telomere dysfunction, human artificial chromosome

Neddylation and anti-tumor immunity Research Perspective

Xiaoguang Wang, Scott Best, Alexey V. Danilov

Published Jun 27, 2021 · Vol. 12, No. 21 · pp. 2227-2230

Keywords: neddylation, T cell, pevonedistat

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

Takayuki Naruse, Takanori Goi, Akio Yamaguchi

Published Jun 23, 2021 · Vol. 12, No. 14 · pp. 1388-1397

Keywords: prokineticin-1, lymphangiogenic activity, colorectal cancer

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Rodney J. Scott, Anurag Mehta, Gabriel S. Macedo, Pavel S. Borisov, Ravindran Kanesvaran, Wafaa El Metnawy

Published Jun 22, 2021 · Vol. 12, No. 16 · pp. 1600-1614

Keywords: metastatic castration-resistant prostate cancer, homologous recombination repair, next generation sequencing, genetic testing

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

Tara Williamson, Michelle Carvalho de Abreu, Dimitri G. Trembath, Cory Brayton, Byunghak Kang, Thais Biude Mendes, Paulo Pimentel de Assumpção, Janete M. Cerutti, Gregory J. Riggins

Published Jun 22, 2021 · Vol. 12, No. 14 · pp. 1326-1338

Keywords: mebendazole, pancreatic cancer, cancer prevention, metastasis, mouse models

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Marina Simón, Jesper Tranekjær Jørgensen, Karina Juhl, Andreas Kjaer

Published Jun 22, 2021 · Vol. 12, No. 14 · pp. 1366-1376

Keywords: photothermal therapy (PTT), indocyanine green (ICG), urokinase plasminogen activator receptor (uPAR), cancer, hyperthermia

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Reza Bayat Mokhtari, Bessi Qorri, Narges Baluch, Angelo Sparaneo, Federico Pio Fabrizio, Lucia Anna Muscarella, Albina Tyker, Sushil Kumar, Hai-Ling Margaret Cheng, Myron R. Szewczuk, Bikul Das, Herman Yeger

Published Jun 22, 2021 · Vol. 12, No. 15 · pp. 1470-1489

Keywords: sulforaphane, acetazolamide, bronchial carcinoid tumors, serotonin, carbonic anhydrase

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Pareesa Kamgar-Dayhoff, Tinatin I. Brelidze

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1406-1426

Keywords: chlorpromazine, repurposing

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Kassidy A. Hebert, Sergio Jaramillo, Wangjie Yu, Min Wang, Ratna Veeramachaneni, Vlad C. Sandulache, Andrew G. Sikora, Mark D. Bonnen, Ananth V. Annapragada, David Corry, Farrah Kheradmand, Raj K. Pandita, Michelle S. Ludwig, Tej K. Pandita, Shixia Huang, Cristian Coarfa, Sandra L. Grimm, Dimuthu Perera, George Miles, Yohannes T. Ghebre

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1339-1353

Keywords: esomeprazole, proton pump inhibitors, ionizing radiation, radiosensitization, tumor control

Clinicopathological utility of human epidermal growth factor receptor 2 (HER2)-heterogeneity for next-generation treatments of triple-negative breast cancer Editorial

Sasagu Kurozumi, Ayaka Katayama, Ken Shirabe, Jun Horiguchi, Emad A. Rakha

Published Jun 19, 2021 · Vol. 12, No. 22 · pp. 2302-2304

Keywords: breast cancer, HER2 low, triple negative, heterogeneity

The role of dynamic phenotypes in cancer Research Perspective

Luana S. Lenz, Guido Lenz

Published Jun 19, 2021 · Vol. 12, No. 19 · pp. 1962-1965

Keywords: dynamic phenotype, fitness, tumor resistance, tumor evolution, single cell

Correction: Transforming growth factor β-induced epithelial-to-mesenchymal signature predicts metastasis-free survival in non-small cell lung cancer Correction

Edna Gordian, Eric A. Welsh, Nicholas Gimbrone, Erin M. Siegel, David Shibata, Ben C. Creelan, William Douglas Cress, Steven A. Eschrich, Eric B. Haura, Teresita Muñoz-Antonia

Published Jun 18, 2021 · Vol. 12, No. 13 · pp. 1325-1325

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Christopher Kolios, Lakshmanan Sannachi, Archya Dasgupta, Harini Suraweera, Daniel DiCenzo, Gregory Stanisz, Arjun Sahgal, Frances Wright, Nicole Look-Hong, Belinda Curpen, Ali Sadeghi-Naini, Maureen Trudeau, Sonal Gandhi, Michael C. Kolios, Gregory J. Czarnota

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1354-1365

Keywords: radiomics, MRI, breast cancer, neoadjuvant chemotherapy, biomarkers

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Maura Argenziano, Chiara Tortora, Alessandra Di Paola, Elvira Pota, Martina Di Martino, Daniela Di Pinto, Caterina Di Leva, Francesca Rossi

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1377-1387

Keywords: acute monocytic leukemia, eltrombopag, deferasirox, iron chelation, cancer

Results from a randomized trial combining trastuzumab with a peptide vaccine suggest a role for HER2-targeted therapy in triple-negative breast cancer Editorial

Anne E. O’Shea, Guy T. Clifton, George E. Peoples

Published Jun 15, 2021 · Vol. 12, No. 23 · pp. 2318-2319

Keywords: HER2, peptide vaccines, nelipepimut-S, triple-negative breast cancer

Targeting AP-1 transcription factors by CRISPR in the prostate Research Perspective

Maria Riedel, Huiqiang Cai, Iben C. Stoltze, Mikkel H. Vendelbo, Erwin F. Wagner, Latifa Bakiri, Martin K. Thomsen

Published Jun 15, 2021 · Vol. 12, No. 19 · pp. 1956-1961

Keywords: AP-1, prostate cancer, CRISPR, mouse models, AAV

Towards precision oncology in angiosarcomas using next generation “omic” technologies Research Perspective

Grace Fangmin Tan, Jason Yongsheng Chan

Published Jun 14, 2021 · Vol. 12, No. 19 · pp. 1953-1955

Keywords: rare cancer, single cell sequencing, chemoresistance, spatial transcriptomics

Glucose starvation induces NADPH collapse and disulfide stress in SLC7A11^high cancer cells Editorial

Xiaoguang Liu, Boyi Gan

Published Jun 12, 2021 · Vol. 12, No. 16 · pp. 1629-1630

Keywords: SLC7A11, cystine, cysteine, NADPH, glucose starvation

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Catherine T. Haring, Chandan Bhambhani, Collin Brummel, Brittany Jewell, Emily Bellile, Molly E. Heft Neal, Erin Sandford, Ryan M. Spengler, Apurva Bhangale, Matthew E. Spector, Jonathan McHugh, Mark E. Prince, Michelle Mierzwa, Francis P. Worden, Muneesh Tewari, Paul L. Swiecicki, J. Chad Brenner

Published Jun 11, 2021 · Vol. 12, No. 13 · pp. 1214-1229

Keywords: HPV, head and neck cancer, oropharyngeal cancer, ctDNA, circulating tumor DNA

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Anjali Gupta, Taofik Oyekunle, Omolola Salako, Adetola Daramola, Olusegun Alatise, Gabriel Ogun, Adewale Adeniyi, April Deveaux, Veeral Saraiya, Allison Hall, Omobolaji Ayandipo, Thomas Olajide, Olalekan Olasehinde, Olukayode Arowolo, Adewale Adisa, Oludolapo Afuwape, Aralola Olusanya, Aderemi Adegoke, Trygve O. Tollefsbol, Donna Arnett, Michael J. Muehlbauer, Christopher B. Newgard, H3 Africa Kidney Research Network, Tomi Akinyemiju

Published Jun 10, 2021 · Vol. 12, No. 13 · pp. 1230-1242

Keywords: C-reactive protein, breast cancer, Nigeria, molecular subtype, menopausal status

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Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Neddylation and anti-tumor immunity Research Perspective

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Clinicopathological utility of human epidermal growth factor receptor 2 (HER2)-heterogeneity for next-generation treatments of triple-negative breast cancer Editorial

The role of dynamic phenotypes in cancer Research Perspective

Correction: Transforming growth factor β-induced epithelial-to-mesenchymal signature predicts metastasis-free survival in non-small cell lung cancer Correction

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Results from a randomized trial combining trastuzumab with a peptide vaccine suggest a role for HER2-targeted therapy in triple-negative breast cancer Editorial

Targeting AP-1 transcription factors by CRISPR in the prostate Research Perspective

Towards precision oncology in angiosarcomas using next generation “omic” technologies Research Perspective

Glucose starvation induces NADPH collapse and disulfide stress in SLC7A11^high cancer cells Editorial

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells Priority Research Paper

Neddylation and anti-tumor immunity Research Perspective

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer Research Paper

The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Clinicopathological utility of human epidermal growth factor receptor 2 (HER2)-heterogeneity for next-generation treatments of triple-negative breast cancer Editorial

The role of dynamic phenotypes in cancer Research Perspective

Correction: Transforming growth factor β-induced epithelial-to-mesenchymal signature predicts metastasis-free survival in non-small cell lung cancer Correction

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Results from a randomized trial combining trastuzumab with a peptide vaccine suggest a role for HER2-targeted therapy in triple-negative breast cancer Editorial

Targeting AP-1 transcription factors by CRISPR in the prostate Research Perspective

Towards precision oncology in angiosarcomas using next generation “omic” technologies Research Perspective

Glucose starvation induces NADPH collapse and disulfide stress in SLC7A11high cancer cells Editorial

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Glucose starvation induces NADPH collapse and disulfide stress in SLC7A11^high cancer cells Editorial