The Oncosearch | Oncotarget

Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis Research Paper

Yuji Morine, Tohru Utsunomiya, Hisami Yamanaka-Okumura, Yu Saito, Shinichiro Yamada, Tetsuya Ikemoto, Satoru Imura, Shohei Kinoshita, Akiyoshi Hirayama, Yasuhito Tanaka, Mitsuo Shimada

Published Oct 27, 2022 · Vol. 13, No. 1 · pp. 1286-1298

Keywords: metabolomics, essential amino acid, hepatocellular carcinoma, diagnostic biomarker

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Jun Gong, Michelle Guan, Haesoo Kim, Natalie Moshayedi, Sejal Mehta, Galen Cook-Wiens, Brent K. Larson, Jenny Zhou, Rishi Patel, Isaac Lapite, Veronica R. Placencio-Hickok, Richard Tuli, Ronald B. Natale, Andrew E. Hendifar

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1202-1214

Keywords: hyaluronan, hyaluronic acid, biomarker, prognostic, predictive

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Masahiko Shibata, Kotaro Nanno, Daigo Yoshimori, Takahiro Nakajima, Makoto Takada, Takashi Yazawa, Kousaku Mimura, Norio Inoue, Takafumi Watanabe, Kazunoshin Tachibana, Satoshi Muto, Tomoyuki Momma, Yoshiyuki Suzuki, Koji Kono, Shungo Endo, Seiichi Takenoshita

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1273-1285

Keywords: MDSC, immunosuppression, Treg, TAM, cancer

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

Neal Murphy, Andrew J. Shih, Paras Shah, Oksana Yaskiv, Houman Khalili, Anthony Liew, Annette T. Lee, Xin-Hua Zhu

Published Oct 20, 2022 · Vol. 13, No. 1 · pp. 1188-1200

Keywords: muscle invasive bladder cancer, neoadjuvant chemotherapy, gene expression, molecular subtyping, canonical correlation analysis

FSP1, a novel KEAP1/NRF2 target gene regulating ferroptosis and radioresistance in lung cancers Research Perspective

Nsengiyumva Emmanuel, Hongen Li, Jing Chen, Yilei Zhang

Published Oct 17, 2022 · Vol. 13, No. 1 · pp. 1136-1139

Keywords: KEAP1/NRF2, lung cancer, ferroptosis, radioresistance, therapy

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Christine Sanders, Jan-Frederic Lau, Dimo Dietrich, Sebastian Strieth, Peter Brossart, Glen Kristiansen

Published Oct 14, 2022 · Vol. 13, No. 1 · pp. 1166-1173

Keywords: Nectin-4, enfortumab-vedotin, HNSCC, p16

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Addendum

Kevin Drenner, Gargi D. Basu, Laurie J. Goodman, Audrey A. Ozols, Janine R. LoBello, Thomas Royce, Michael S. Gordon, Erkut H. Borazanci, Margaux A. Steinbach, Jeffrey Trent, Sunil Sharma

Published Oct 13, 2022 · Vol. 13, No. 1 · pp. 1174-1174

Addendum: Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Addendum

Marcel Kemper, Georg Evers, Arik Bernard Schulze, Jan Sperveslage, Christoph Schülke, Georg Lenz, Thomas Herold, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Annalen Bleckmann

Published Oct 13, 2022 · Vol. 13, No. 1 · pp. 1216-1216

Addendum: Significant efficacy and well safety of apatinib in an advanced liver cancer patient: a case report and literature review Addendum

Peisi Kou, Yan Zhang, Wenbo Shao, Hui Zhu, Jingze Zhang, Haiyong Wang, Li Kong, Jinming Yu

Published Oct 11, 2022

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models Research Paper

Diala Ghazal, Fatma Zalzala, John C. Fisk, Swetha Tati, Loukia G. Karacosta, Susan Morey, James R. Olson, Sally Quataert, Grace K. Dy, Kate Rittenhouse-Olson

Published Oct 7, 2022 · Vol. 13, No. 1 · pp. 1155-1164

Keywords: hJAA-F11, TF-Ag, Thomsen-Friedenreich antigen, tumor immunotherapy, translational oncology

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer Research Paper

Romana Moench, Martin Gasser, Karol Nawalaniec, Tanja Grimmig, Amrendra K. Ajay, Larissa Camila Ribeiro de Souza, Minghua Cao, Yueming Luo, Petra Hoegger, Carmen M. Ribas, Jurandir M. Ribas-Filho, Osvaldo Malafaia, Reinhard Lissner, Li-Li Hsiao, Ana Maria Waaga-Gasser

Published Oct 6, 2022 · Vol. 13, No. 1 · pp. 1140-1152

Keywords: PDGF, VEGFR, EGFR, bypassed signaling, colorectal cancer

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Research Paper

Michael Jonathan Kucharczyk, Andrew Bang, Michael C. Tjong, Stefania Papatheodorou, Jesus C. Fabregas

Published Sep 30, 2022 · Vol. 13, No. 1 · pp. 1109-1119

Keywords: radiotherapy, meta-analysis, systematic review, rectal cancer, total mesorectal excision

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained Research Paper

Liza A. Wijler, Francina J. Dijk, Hanil Quirindongo, Danielle A.E. Raats, Bram Dorresteijn, Matthew J.W. Furber, Anne M. May, Onno Kranenburg, Miriam van Dijk

Published Sep 27, 2022 · Vol. 13, No. 1 · pp. 1094-1108

Keywords: C2C12 myotubes, chemotherapy, chemotherapy-associated toxicity, colorectal cancer, nutrients, tumor (organoid) cells

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Benigno C. Valdez, Yago Nieto, Bin Yuan, David Murray, Borje S. Andersson

Published Sep 24, 2022 · Vol. 13, No. 1 · pp. 1122-1135

Keywords: poly(ADP-ribosyl)ation, HDAC inhibitors, PARP inhibitors, chemotherapy, hematologic malignancy

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Jude B. Khatib, Emily M. Schleicher, Lindsey M. Jackson, Ashna Dhoonmoon, George-Lucian Moldovan, Claudia M. Nicolae

Published Sep 23, 2022 · Vol. 13, No. 1 · pp. 1078-1091

Keywords: PARP10, ATM, CRISPR screens, genome stability, cancer cell proliferation

Genomic alterations predictive of poor clinical outcomes in pan-cancer Research Paper

Crystal S. Seldon, Karthik Meiyappan, Hannah Hoffman, Jimmy A. Guo, Neha Goel, William L. Hwang, Paul L. Nguyen, Brandon A. Mahal, Mohammed Alshalalfa

Published Sep 20, 2022 · Vol. 13, No. 1 · pp. 1069-1077

Keywords: genomic alterations, TP53, TCGA, poor prognosis

Site of analysis matters - Ongoing complete response to Nivolumab in a patient with HIV/HPV related metastatic anal cancer and MLH1 mutation Research Paper

Melanie Demes, Ursula Pession, Jan Jeroch, Falko Schulze, Katrin Eichler, Daniel Martin, Peter Wild, Oliver Waidmann

Published Sep 8, 2022 · Vol. 13, No. 1 · pp. 1034-1042

Keywords: anal cancer, microsatellite instability, immunotherapy, high-throughput nucleotide sequencing, nivolumab

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Daiki Ueno, Juan C. Vasquez, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Sam Friedman, Randy Caliliw, Shinji Ohtake, Xun Bao, Jing Li, Huihui Ye, Karla Boyd, Rong Rong Huang, Jack Dodson, Paul Boutros, Ranjit S. Bindra, Brian Shuch

Published Sep 3, 2022 · Vol. 13, No. 1 · pp. 1054-1067

Keywords: FH, SDHB, renal cell carcinoma, PARP inhibitor, temozolomide

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma Research Paper

Aayush Aayush, Saloni Darji, Deepika Dhawan, Alexander Enstrom, Meaghan M. Broman, Muhammad T. Idrees, Hristos Kaimakliotis, Timothy Ratliff, Deborah Knapp, David Thompson

Published Aug 27, 2022 · Vol. 13, No. 1 · pp. 1004-1016

Keywords: bladder cancer, elastin-like polypeptide, NIR imaging, epidermal growth factor receptor (EGFR), translational studies

Correction: Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Correction

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa, Sônia Nair Báo

Published Aug 5, 2022 · Vol. 13, No. 1 · pp. 1068-1068

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Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis Research Paper

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

FSP1, a novel KEAP1/NRF2 target gene regulating ferroptosis and radioresistance in lung cancers Research Perspective

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Addendum

Addendum: Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Addendum

Addendum: Significant efficacy and well safety of apatinib in an advanced liver cancer patient: a case report and literature review Addendum

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models Research Paper

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer Research Paper

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Research Paper

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained Research Paper

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Genomic alterations predictive of poor clinical outcomes in pan-cancer Research Paper

Site of analysis matters - Ongoing complete response to Nivolumab in a patient with HIV/HPV related metastatic anal cancer and MLH1 mutation Research Paper

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma Research Paper

Correction: Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis Research Paper

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

FSP1, a novel KEAP1/NRF2 target gene regulating ferroptosis and radioresistance in lung cancers Research Perspective

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series Addendum

Addendum: Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Addendum

Addendum: Significant efficacy and well safety of apatinib in an advanced liver cancer patient: a case report and literature review Addendum

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models Research Paper

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer Research Paper

Effectiveness of radiotherapy for local control in T3N0 rectal cancer managed with total mesorectal excision: a meta-analysis Research Paper

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained Research Paper

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Genomic alterations predictive of poor clinical outcomes in pan-cancer Research Paper

Site of analysis matters - Ongoing complete response to Nivolumab in a patient with HIV/HPV related metastatic anal cancer and MLH1 mutation Research Paper

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma Research Paper

Correction: Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Correction