The Oncosearch | Oncotarget

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

Swapna Asuthkar, Kiran Kumar Velpula, Chandramu Chetty, Bharathi Gorantla, Jasti S. Rao

Published Nov 16, 2012 · Vol. 3, No. 11 · pp. 1439-1454

Keywords: Matrix metalloproteinase-9 (MMP-9), microRNA-211 (miR-211), Cancer Stem Cells (CSC), Ionizing radiation (IR) and Temozolomide (Tem)

High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells Research

Parvinder Hothi, Timothy J. Martins, LiPing Chen, Loic Deleyrolle, Jae-Geun Yoon, Brent Reynolds, Greg Foltz

Published Oct 23, 2012 · Vol. 3, No. 10 · pp. 1124-1136

Keywords: disulfiram, glioblastoma, high-throughput chemical screens, stem cells

Effects of Ectopic Expression of NGAL on Doxorubicin Sensitivity. Research Paper

William H Chappell, Stephen L. Abrams, Richard A Franklin, Giuseppe Montalto, Melchiorre Cervello, Alberto M Martelli, Saverio Candido, Massimo Libra, Jerry Polesel, Renato Talamini, Ralph Arlinghaus, Linda S Steelman, James A McCubrey

Published Oct 20, 2012 · Vol. 3, No. 10 · pp. 1236-1245

Keywords: NGAL, Lcn2, Doxorubicin, lipocalins, siderocalins, iron transport, MMP-9, drug resistance

Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide Research

Joanna Triscott, Cathy Lee, Kaiji Hu, Abbas Fotovati, Rachel Berns, Mary Pambid, Margaret Luk, Richard E Kast, Esther Kong, Eric Toyota, Stephen Yip, Brian Toyota, Sandra E Dunn

Published Oct 8, 2012 · Vol. 3, No. 10 · pp. 1112-1123

Keywords: glioblastoma, disulfiram, temozolomide, brain tumor, drug resistance

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration Research Paper

VÃ©ronique Frattini, Federica Pisati, Maria Carmela Speranza, Pietro Luigi Poliani, Gianmaria FrigÃ©, Gabriele Cantini, Dimos Kapetis, Manuela Cominelli, Alessandra Rossi, Gaetano Finocchiaro, Serena Pellegatta

Published Sep 22, 2012 · Vol. 3, No. 10 · pp. 1146-1157

Keywords: FOXP3, glioblastoma, neurospheres, proliferation, migration

Mutant IDH1 is required for IDH1 mutated tumor cell growth Brief Reports

Genglin Jin, Christopher J. Pirozzi, Lee H. Chen, Christopher G. Duncan, Giselle Y. Lopez, Jie Feng, Ivan Spasojevic, Darell D. Bigner, Yiping He, Hai Yan

Published Aug 9, 2012 · Vol. 3, No. 8 · pp. 774-782

Keywords: IDH1, cell survival

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma Research Paper

Maria Carmela Speranza, VÃ©ronique Frattini, Federica Pisati, Dimos Kapetis, Paola Porrati, Marica Eoli, Serena Pellegatta, Gaetano Finocchiaro

Published Aug 5, 2012 · Vol. 3, No. 7 · pp. 723-734

Keywords: miR-145, NEDD9, invasion, progression, glioma, glioblastoma

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas Research Paper

Yuchen Jiao, Patrick J. Killela, Zachary J. Reitman, B.Ahmed Rasheed, Christopher M. Heaphy, Roeland F. de Wilde, Fausto J. Rodriguez, Sergio Rosemberg, Sueli Meiko Obashinjo, Suely Kazue Nagahashi Marie, Chetan Bettegowda, Nishant Agrawal, Eric Lipp, Christopher Pirozzi, Giselle Lopez, Yiping He, Henry Friedman, Allan H. Friedman, Gregory J. Riggins, Matthias Holdhoff, Peter Burger, Roger McLendon, Darell D. Bigner, Bert Vogelstein, Alan K. Meeker, Kenneth W. Kinzler, Nickolas Papadopoulos, Luis A. Diaz, Jr., Hai Yan

Published Aug 3, 2012 · Vol. 3, No. 7 · pp. 709-722

Keywords: ALT, IDH1, IDH2, Mixed Gliomas

Novel Therapeutic Targets in the Brain Tumor Microenvironment Research Perspective

Joanna J. Phillips

Published May 25, 2012 · Vol. 3, No. 5 · pp. 568-575

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival Research Paper

Ian Lee, Patricia S. Fox, Sherise D. Ferguson, Roland L. Bassett, Jr., Ling-Yuan Kong, Christopher W. Schacherer, Jeffrey E. Gershenwald, Elizabeth A. Grimm, Gregory N. Fuller, Amy B. Heimberger

Published Apr 6, 2012 · Vol. 3, No. 3 · pp. 336-344

Keywords: melanoma, p-STAT3, CNS metastasis, prognosis

Ras inhibition by FTS attenuates brain tumor growth in mice directly and by enhancing reactivity of cytotoxic lymphocytes Research Paper

Elizabeta Aizman, Adi Mor, Ayelet Levy, Jacob George, Yoel Kloog

Published Feb 7, 2012 · Vol. 3, No. 2 · pp. 144-157

Keywords: Ras, Glioblastoma, CTL, FTS, Salirasib

Capturing the Molecular and Biological Diversity of High-Grade Astrocytoma in Genetically Engineered Mouse Models Research Perspective

Lionel M.L. Chow, Suzanne J. Baker

Published Jan 25, 2012 · Vol. 3, No. 1 · pp. 67-77

Keywords: glioblastoma, astrocytoma, mouse model, PI3K pathway

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders Review

Sharmin Esmailzadeh, Xiaoyan Jiang

Published Dec 30, 2011 · Vol. 2, No. 12 · pp. 918-934

Keywords: AHI-1, oncogene, CML, CTCL, AHI-1-BCR-ABL-JAK2 interaction complex, tyrosine kinase inhibitors, leukemic stem cells, TKI resistance

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Dannis Gilbert Van Vuurden, Esther Hulleman, Olga L.M. Meijer, Laurine E. Wedekind, Marcel Kool, Hendrik Witt, W. Peter Vandertop, Thomas WÃ¼rdinger, David P. Noske, Gertjan J.L. Kaspers, Jacqueline Cloos

Published Dec 15, 2011 · Vol. 2, No. 12 · pp. 984-996

Keywords: PARP, radiation, medulloblastoma, ependymoma, glioma, pediatric

Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells Research Paper

Genevieve L. Weber, Marie-Odile Parat, Zev A. Binder, Gary L. Gallia, Gregory J. Riggins

Published Nov 5, 2011 · Vol. 2, No. 11 · pp. 833-849

Keywords: glioblastoma, pathway analysis, PIK3CA, PIK3R1, invasion, PI3K

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases Research Paper

Akshal S. Patel, Joshua E. Allen, David T. Dicker, Kristi L. Peters, Jonas M. Sheehan, Michael J. Glantz, Wafik S. El-Deiry

Published Oct 8, 2011 · Vol. 2, No. 10 · pp. 752-760

Keywords: circulating tumor cells, carcinomatous meningitis, breast cancer, brain metastases, intrathecal chemotherapy, cancer monitoring

Mouse Models to Interrogate the Implications of the Differentiation Status In the Ontogeny of Gliomas Review

Diana Marcela MuÃ±oz, Abhijit Guha

Published Sep 3, 2011 · Vol. 2, No. 8 · pp. 590-598

Keywords: Glioblastoma Multiforme (GBM), Tumor Heterogeneity, Tumor Microenvironment, Brain Tumor Stem Cells (BTSC)

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers Research Paper

Michael Christoph Haffner, Alcides Chaux, Alan K Meeker, David Esopi, Jonathan Gerber, Laxmi G. Pellakuru, Antoun Toubaji, Pedram Argani, Christine Iacobuzio-Donahue, William G. Nelson, George J. Netto, Angelo DeMarzo, Srinivasan Yegnasubramanian

Published Sep 2, 2011 · Vol. 2, No. 8 · pp. 627-637

Keywords: 5-hydroxymethylcytosine, 5hmC, DNA methylation, differentiation, cancer, tissue stem / progenitor cells

The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses Review

Bart Thaci, Ilya V. Ulasov, Derek V. Wainwright, Maciej S. Lesniak

Published Mar 5, 2011 · Vol. 2, No. 3 · pp. 113-121

Keywords: Adenovirus, interferon, interleukin-1, innate immune response

A Robust Approach to Enhance Tumor-selective Accumulation of Nanoparticles Research Paper

Yuan Qiao, Xin Huang, Sridhar Nimmagadda, Renyuan Bai, Verena Staedtke, Catherine A. Foss, Ian Cheong, Matthias Holdhoff, Yoshinori Kato, Martin G. Pomper, Gregory J. Riggins, Kenneth W. Kinzler, Luis A. Diaz, Bert Vogelstein, Shibin Zhou

Published Mar 1, 2011 · Vol. 2, No. 1-2 · pp. 59-68

Keywords: Tumor, Vasculature, Nanoparticle, Inflammation, TNF-Î±

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells Research

Effects of Ectopic Expression of NGAL on Doxorubicin Sensitivity. Research Paper

Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide Research

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration Research Paper

Mutant IDH1 is required for IDH1 mutated tumor cell growth Brief Reports

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma Research Paper

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas Research Paper

Novel Therapeutic Targets in the Brain Tumor Microenvironment Research Perspective

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival Research Paper

Ras inhibition by FTS attenuates brain tumor growth in mice directly and by enhancing reactivity of cytotoxic lymphocytes Research Paper

Capturing the Molecular and Biological Diversity of High-Grade Astrocytoma in Genetically Engineered Mouse Models Research Perspective

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders Review

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells Research Paper

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases Research Paper

Mouse Models to Interrogate the Implications of the Differentiation Status In the Ontogeny of Gliomas Review

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers Research Paper

The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses Review

A Robust Approach to Enhance Tumor-selective Accumulation of Nanoparticles Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity Research Paper

High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells Research

Effects of Ectopic Expression of NGAL on Doxorubicin Sensitivity. Research Paper

Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide Research

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration Research Paper

Mutant IDH1 is required for IDH1 mutated tumor cell growth Brief Reports

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma Research Paper

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas Research Paper

Novel Therapeutic Targets in the Brain Tumor Microenvironment Research Perspective

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival Research Paper

Ras inhibition by FTS attenuates brain tumor growth in mice directly and by enhancing reactivity of cytotoxic lymphocytes Research Paper

Capturing the Molecular and Biological Diversity of High-Grade Astrocytoma in Genetically Engineered Mouse Models Research Perspective

AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders Review

PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation Research Paper

Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells Research Paper

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases Research Paper

Mouse Models to Interrogate the Implications of the Differentiation Status In the Ontogeny of Gliomas Review

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers Research Paper

The Challenge for Gene Therapy: Innate Immune Response to Adenoviruses Review

A Robust Approach to Enhance Tumor-selective Accumulation of Nanoparticles Research Paper