The Oncosearch | Oncotarget

Amyloid accumulation is a late event in sporadic Alzheimerâ€™s disease-like pathology in nontransgenic rats Research Paper

Natalia A. Stefanova, Natalia A. Muraleva, Elena E. Korbolina, Elena Kiseleva, Kseniya Yi. Maksimova, Nataliya G. Kolosova

Published Dec 24, 2014 · Vol. 6, No. 3 · pp. 1396-1413

Keywords: Alzheimerâ€™s disease, amyloid Î², tau, synaptic losses, neurodegeneration, mitochondria, OXYS rats

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

Valentina Fogal, Ivan Babic, Ying Chao, Sandra Pastorino, Rajesh Mukthavaram, Pengfei Jiang, Yoon-Jae Cho, Sandeep C. Pingle, John R. Crawford, David E. Piccioni, Santosh Kesari

Published Dec 22, 2014 · Vol. 6, No. 2 · pp. 1157-1170

Keywords: mitochondrial p32, c-Myc, glutamine addiction, brain cancer

Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas Research Paper

Angela Margarida Costa, Filipe Pinto, Olga Martinho, Maria JosÃ© Oliveira, Peter Jordan, Rui Manuel Reis

Published Dec 22, 2014 · Vol. 6, No. 3 · pp. 1422-1434

A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma Research Paper

Fengfei Wang, Marc Remke, Kruttika Bhat, Eric T. Wong, Shuang Zhou, Vijay Ramaswamy, Adrian Dubuc, Ekokobe Fonkem, Saeed Salem, Hongbing Zhang, Tze-chen Hsieh, Stephen T. O'Rourke, Lizi Wu, David W. Li, Cynthia Hawkins, Isaac S. Kohane, Joseph M. Wu, Min Wu, Michael D. Taylor, Erxi Wu

Published Dec 17, 2014 · Vol. 6, No. 5 · pp. 2709-2724

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Jara Majuelos-Melguizo, MarÃa Isabel RodrÃguez, Laura LÃ³pez-JimÃ©nez, Jose M. RodrÃguez-Vargas, Juan M. MartÃ MartÃn-Consuegra, Santiago Serrano-SÃ¡enz, Julie Gavard, J. Mariano Ruiz de AlmodÃ³var, F. Javier Oliver

Published Dec 11, 2014 · Vol. 6, No. 7 · pp. 4790-4803

New insights into the genetics of glioblastoma multiforme by familial exome sequencing Research Paper

Christina Backes, Christian Harz, Ulrike Fischer, Jana Schmitt, Nicole Ludwig, Britt-Sabina Petersen, Sabine C. Mueller, Yoo-Jin Kim, Nadine M. Wolf, Hugo A. Katus, Benjamin Meder, Rhoikos FurtwÃ¤ngler, Andre Franke, Rainer Bohle, Wolfram Henn, Norbert Graf, Andreas Keller, Eckart Meese

Published Dec 10, 2014 · Vol. 6, No. 8 · pp. 5918-5931

WW domain-containing oxidoreductase in neuronal injury and neurological diseases Review

Hsin-Tzu Chang, Chan-Chuan Liu, Shur-Tzu Chen, Ye Vone Yap, Nan-Shang Chang, Chun-I Sze

Published Dec 10, 2014 · Vol. 5, No. 23 · pp. 11792-11799

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

Michael Ehrhardt, Rogerio B. Craveiro, Martin I. Holst, Torsten Pietsch, Dagmar Dilloo

Published Dec 6, 2014 · Vol. 6, No. 2 · pp. 802-813

Keywords: medulloblastoma, GDC-0941, PI3K inhibitor, targeted therapy, c-myc

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe Research Paper

Elodie A. PÃ©rÃ¨s, AurÃ©lie N. GÃ©rault, Samuel Valable, Simon Roussel, JÃ©rÃ´me Toutain, Didier Divoux, Jean-SÃ©bastien Guillamo, Marc Sanson, Myriam Bernaudin, Edwige Petit

Published Dec 3, 2014 · Vol. 6, No. 4 · pp. 2101-2119

Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells Research Paper

Jie Qiao, Shu-Jian Cui, Lei-Lei Xu, Si-Jie Chen, Jun Yao, Ying-Hua Jiang, Gang Peng, Cai-Yun Fang, Peng-Yuan Yang, Feng Liu

Published Nov 28, 2014 · Vol. 6, No. 2 · pp. 1171-1189

Synthetic AÎ² peptides acquire prion-like properties in the brain Research Paper

Xiangzhu Xiao, Ignazio Cali, Jue Yuan, Laura Cracco, Paul Curtiss, Liang Zeng, Mai Abouelsaad, Dimitris Gazgalis, Gong-Xian Wang, Qingzhong Kong, Hisashi Fujioka, Gianfranco Puoti, Wen-Quan Zou

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 642-650

Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis Priority Research Paper

Yong Zhang, Shinji Miwa, Nan Zhang, Robert M. Hoffman, Ming Zhao

Published Nov 15, 2014 · Vol. 6, No. 5 · pp. 2615-2622

RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification Research Paper

Paulina Ä†wiek, Zaira Leni, Fabiana Salm, Valeriya Dimitrova, Beata Styp-Rekowska, Gianpaolo Chiriano, Michael Carroll, Katrin HÃ¶land, Valentin Djonov, Leonardo Scapozza, Patrick Guiry, Alexandre Arcaro

Published Nov 6, 2014 · Vol. 6, No. 1 · pp. 116-129

MicroRNA expression patterns in the malignant progression of gliomas and a 5-microRNA signature for prognosis Research Paper

Wei Yan, Rui Li, Yanwei Liu, Pei Yang, Zheng Wang, Chuanbao Zhang, Zhaoshi Bao, Wei Zhang, Yongping You, Tao Jiang

Published Nov 4, 2014 · Vol. 5, No. 24 · pp. 12908-12915

Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis Research Paper

Xing Liu, Xiaofeng Wang, Wenzhong Du, Lingchao Chen, Guangzhi Wang, Yuqiong Cui, Yang Liu, Zhijin Dou, Hongjun Wang, Ping Zhang, Liang Chang, Liye Yi, Jinquan Cai, Chuanlu Jiang

Published Oct 29, 2014 · Vol. 5, No. 22 · pp. 11681-11694

Co-treatment with therapeutic neural stem cells expressing carboxyl esterase and CPT-11 inhibit growth of primary and metastatic lung cancers in mice Research Paper

Bo-Rim Yi, Seung U. Kim, Kyung-Chul Choi

Published Oct 24, 2014 · Vol. 5, No. 24 · pp. 12835-12848

Keywords: Lung cancer, metastasis, interferon-beta, 5-fluorocytosine, stem cell therapy

Proscillaridin A is cytotoxic for glioblastoma cell lines and controls tumor xenograft growth in vivo Research Paper

Emilie DenicolaÃ¯, Nathalie Baeza-Kallee, AurÃ©lie Tchoghandjian, Manon CarrÃ©, Carole Colin, Carine Jiguet Jiglaire, Sandy Mercurio, Christophe Beclin, Dominique Figarella-Branger

Published Oct 21, 2014 · Vol. 5, No. 21 · pp. 10934-10948

Keywords: Proscillaridin A, glioblastoma, cytotoxicity, tumor growth control, Na+/K+ ATPase Î±1 subunit

GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer Research Paper

Glen P. Marszalowicz, Adam E. Snook, Michael S. Magee, Dante Merlino, Lisa D. Berman-Booty, Scott A. Waldman

Published Sep 8, 2014 · Vol. 5, No. 19 · pp. 9460-9471

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway Research Paper

Jun-Bum Park, Sameer Agnihotri, Brian Golbourn, Kelsey C. Bertrand, Amanda Luck, Nesrin Sabha, Christian A. Smith, Sara Byron, Gelareh Zadeh, Sidney Croul, Michael Berens, James T. Rutka

Published Sep 5, 2014 · Vol. 5, No. 19 · pp. 9382-9395

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Research Paper

Suganthi Chittaranjan, Susanna Chan, Cindy Yang, Kevin C. Yang, Vincent Chen, Annie Moradian, Marlo Firme, Jungeun Song, Nancy E. Go, Michael D. Blough, Jennifer A. Chan, Gregory J. Cairncross, Sharon M. Gorski, Gregg B. Morin, Stephen Yip, Marco A. Marra

Published Aug 27, 2014 · Vol. 5, No. 17 · pp. 7960-7979

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Amyloid accumulation is a late event in sporadic Alzheimerâ€™s disease-like pathology in nontransgenic rats Research Paper

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas Research Paper

A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

New insights into the genetics of glioblastoma multiforme by familial exome sequencing Research Paper

WW domain-containing oxidoreductase in neuronal injury and neurological diseases Review

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe Research Paper

Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells Research Paper

Synthetic AÎ² peptides acquire prion-like properties in the brain Research Paper

Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis Priority Research Paper

RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification Research Paper

MicroRNA expression patterns in the malignant progression of gliomas and a 5-microRNA signature for prognosis Research Paper

Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis Research Paper

Co-treatment with therapeutic neural stem cells expressing carboxyl esterase and CPT-11 inhibit growth of primary and metastatic lung cancers in mice Research Paper

Proscillaridin A is cytotoxic for glioblastoma cell lines and controls tumor xenograft growth in vivo Research Paper

GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer Research Paper

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway Research Paper

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Amyloid accumulation is a late event in sporadic Alzheimerâ€™s disease-like pathology in nontransgenic rats Research Paper

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas Research Paper

A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

New insights into the genetics of glioblastoma multiforme by familial exome sequencing Research Paper

WW domain-containing oxidoreductase in neuronal injury and neurological diseases Review

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe Research Paper

Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells Research Paper

Synthetic AÎ² peptides acquire prion-like properties in the brain Research Paper

Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis Priority Research Paper

RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification Research Paper

MicroRNA expression patterns in the malignant progression of gliomas and a 5-microRNA signature for prognosis Research Paper

Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis Research Paper

Co-treatment with therapeutic neural stem cells expressing carboxyl esterase and CPT-11 inhibit growth of primary and metastatic lung cancers in mice Research Paper

Proscillaridin A is cytotoxic for glioblastoma cell lines and controls tumor xenograft growth in vivo Research Paper

GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer Research Paper

Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway Research Paper

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity Research Paper