The Oncosearch | Oncotarget

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine Research Paper

Masamichi Hayashi, Heike Bernert, Luciane Tsukamoto Kagohara, Leonel Maldonado, Mariana Brait, Mark Schoenberg, Trinity Bivalacqua, George J. Netto, Wayne Koch, David Sidransky, Mohammad O. Hoque

Published May 7, 2014 · Vol. 5, No. 10 · pp. 3350-3361

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation Research Paper

Ming Yuan, Charles G. Eberhart, Mihoko Kai

Published Apr 27, 2014 · Vol. 5, No. 9 · pp. 2820-2826

Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes Research Paper

Konrad Gabrusiewicz, Dan Liu, Nahir Cortes-Santiago, Mohammad B. Hossain, Charles A. Conrad, Kenneth D. Aldape, Gregory N. Fuller, Frank C. Marini, Marta M. Alonso, Miguel Angel Idoate, Mark R. Gilbert, Juan Fueyo, Candelaria Gomez-Manzano

Published Apr 11, 2014 · Vol. 5, No. 8 · pp. 2208-2220

Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma Research Paper

Alex Cazes, Lucille Lopez-Delisle, Konstantina Tsarovina, CÃ©cile Pierre-EugÃ¨ne, Katleen De Preter, Michel Peuchmaur, AndrÃ© Nicolas, Claire Provost, Caroline Louis-Brennetot, Romain Daveau, Candy Kumps, Ilaria Cascone, Gudrun Schleiermacher, AurÃ©lie Prignon, Frank Speleman, Hermann Rohrer, Olivier Delattre, Isabelle Janoueix-Lerosey

Published Apr 2, 2014 · Vol. 5, No. 9 · pp. 2688-2702

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma Research Paper

Sujatha Venataraman, Irina Alimova, Peter Harris, Diane K Birks, Illango Balakrishnan, Marc Remke, Michael D Taylor, Michael Handler, Nicholas K Foreman, Rajeev Vibhakar

Published Mar 31, 2014 · Vol. 5, No. 9 · pp. 2355-2371

Keywords: Medulloblastoma, Myc, BRD4, JQ1, Senescence

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Jinquan Cai, Pei Yang, Chuanbao Zhang, Wei Zhang, Yanwei Liu, Zhaoshi Bao, Xing Liu, Wenzhong Du, Hongjun Wang, Tao Jiang, Chuanlu Jiang

Published Mar 21, 2014 · Vol. 5, No. 9 · pp. 2551-2561

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Harriet Wikman, Laura Westphal, Felicitas Schmid, Sirkku Pollari, Jolanthe Kropidlowski, Bettina Sielaff-Frimpong, Markus Glatzel, Jakob Matschke, Manfred Westphal, Kristiina Iljin, Heini Huhtala, Luigi Terracciano, Anne Kallioniemi, Guido Sauter, Volkmar MÃ¼ller, Isabell Witzel, Katrin Lamszus, Dirk Kemming, Klaus Pantel

Published Mar 16, 2014 · Vol. 5, No. 10 · pp. 3076-3087

HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation Research Paper

Charles Cobbs, Sabeena Khan, Lisa Matlaf, Sean McAllister, Alex Zider, Garret Yount, Kenneth Rahlin, Lualhati Harkins, Vladimir Bezrookove, Eric Singer, Liliana Soroceanu

Published Mar 12, 2014 · Vol. 5, No. 4 · pp. 1091-1100

MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme Research Paper

Kristina H. Knubel, Ben M. Pernu, Alexandra Sufit, Sarah Nelson, Angela M. Pierce, Amy K. Keating

Published Mar 12, 2014 · Vol. 5, No. 5 · pp. 1338-1351

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Patrick J. Killela, Christopher J. Pirozzi, Patrick Healy, Zachary J. Reitman, Eric Lipp, Ahmed B. Rasheed, Rui Yang, Bill H. Diplas, Zhaohui Wang, Paula K. Greer, Huishan Zhu, Catherine Y. Wang, Austin B. Carpenter, Henry Friedman, Allan H. Friedman, Stephen T. Keir, Jie He, Yiping He, Roger E. McLendon, James E. Herndon II, Hai Yan, Darell D. Bigner

Published Jan 28, 2014 · Vol. 5, No. 6 · pp. 1515-1525

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Marcus Winter, Martina Ott, Katharina Ochs, Christian Lutz, Xiangdong Liu, Natasa Anastasov, Irina Lehmann, Thomas HÃ¶fer, Andreas von Deimling, Wolfgang Wick, Michael Platten

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1038-1051

Keywords: IDO, immunosuppression, autoactivation loop

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Adrienne L. Watson, Bryant J. Keller, Kyle A. Williams, Namrata N. Damle, Samuel J. Finnerty, Leah K. Anderson, Andrew D. Greeley, Vincent W. Keng, Eric P. Rahrmann, Amanda L. Halfond, Natasha M. Powell, Margaret H. Collins, Tilat Rizvi, Christopher L. Moertel, Nancy Ratner, David A. Largaespada

Published Jan 20, 2014 · Vol. 5, No. 6 · pp. 1502-1514

Keywords: Malignant peripheral nerve sheath tumors, plexiform neurofibromas, Schwann cells, neurofibromatosis type 1 syndrome, neurofibromin 1, PI3K/AKT/mTOR signaling, MAPK signaling, targeted therapies, genetically engineered mouse models, combination therapy

Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function Research Paper

Bongkun Choi, Eun-Jin Lee, Da-Hyun Song, Sung-Chul Yoon, Yeon-Ho Chung, Yongsaeng Jang, Sang-Min Kim, Youngsup Song, Sang-Wook Kang, Seung-Yong Yoon, Eun-Ju Chang

Published Jan 15, 2014 · Vol. 5, No. 2 · pp. 481-492

Keywords: breast cancer, PTX3, osteoclast, RANKL, osteolysis

Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma Research Paper

Catherine Gratas, Quentin SÃ©ry, Marion RabÃ©, Lisa Oliver, FranÃ§ois M. Vallette

Published Jan 1, 2014 · Vol. 5, No. 9 · pp. 2428-2435

Keywords: cell death, Bcl-2 family, glioma, temozolomide

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Lotte Hiddingh, Bakhos A. Tannous, Jian Teng, Bas Tops, Judith Jeuken, Esther Hulleman, Sandra H. Boots-Sprenger, W. Peter Vandertop, David P. Noske, Gertjan J.L. Kaspers, Pieter Wesseling, Thomas Wurdinger

Published Dec 7, 2013 · Vol. 5, No. 2 · pp. 363-374

Keywords: Temozolomide resistance, glioblastoma, EFEMP1, Î³-secretase, Notch, GSI

Chemokines in tumor progression and metastasis Review

Purvaba J. Sarvaiya, Donna Guo, Ilya V. Ulasov, Patrik Gabikian, Maciej S. Lesniak

Published Nov 9, 2013 · Vol. 4, No. 12 · pp. 2171-2185

Keywords: Chemokines, chemokine receptors, cancer, metastasis

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Changcun Guo, Lee H. Chen, Yafen Huang, Chun-Chi Chang, Ping Wang, Christopher J. Pirozzi, Xiaoxia Qin, Xuhui Bao, Paula K. Greer, Roger E. McLendon, Hai Yan, Stephen T. Keir, Darell D. Bigner, Yiping He

Published Nov 3, 2013 · Vol. 4, No. 11 · pp. 2144-2153

Keywords: MLL2, isogenic cell line, gene knockout, enhancer

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Kaiming Xu, Lanfang Wang, Hui-Kuo G. Shu

Published Oct 31, 2013 · Vol. 5, No. 5 · pp. 1241-1252

Keywords: glioblastoma, brain tumor, tumorigenesis, cyclooxygenase-2, Id1

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

Anton George Henssen, Theresa Thor, Andrea Odersky, Lukas Heukamp, Nicolai El-Hindy, Anneleen Beckers, Frank Slpeleman, Kristina Althoff, Simon SchÃ¤fers, Alexander Schramm, Ulrich Sure, Gudrun Fleischhack, Angelika Eggert, Johannes Hubertus Schulte

Published Oct 27, 2013 · Vol. 4, No. 11 · pp. 2080-2095

Keywords: BET bromodomains, BRD4, MYC, JQ1, pediatric brain tumors, targeted therapy

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Jennifer Munkley, Prabhakar Rajan, Nicholas P. Lafferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, David J. Elliott

Published Oct 21, 2013 · Vol. 5, No. 1 · pp. 131-139

Keywords: TSC2, mTOR, mRNA isoform, androgen, prostate cancer

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Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine Research Paper

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation Research Paper

Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes Research Paper

Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma Research Paper

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma Research Paper

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation Research Paper

MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme Research Paper

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function Research Paper

Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma Research Paper

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Chemokines in tumor progression and metastasis Review

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine Research Paper

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation Research Paper

Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes Research Paper

Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma Research Paper

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma Research Paper

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation Research Paper

MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme Research Paper

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function Research Paper

Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma Research Paper

EFEMP1 induces Î³-secretase/Notch-mediated temozolomide resistance in glioblastoma Research Paper

Chemokines in tumor progression and metastasis Review

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

BET bromodomain protein inhibition is a therapeutic option for medulloblastoma Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper