The Oncosearch | Oncotarget

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Tetsuyuki Takahashi, Hisanori Uehara, Hirohisa Ogawa, Hitomi Umemoto, Yoshimi Bando, Keisuke Izumi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4829-4844

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Hui Zhang, Huanwen Wu, Jian Guan, Li Wang, Xinyu Ren, Xiaohua Shi, Zhiyong Liang, Tonghua Liu

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 3085-3097

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms Research Paper

Daniel Kaemmerer, Christiane Reimann, Elisa Specht, Ralph M. Wirtz, Manal Sayeg, Richard P. Baum, Stefan Schulz, Amelie Lupp

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 3346-3358

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

Duane H. Hamilton, Romaine I. Fernando, Jeffrey Schlom, Claudia Palena

Published Dec 26, 2014 · Vol. 6, No. 7 · pp. 4853-4862

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa

Published Dec 19, 2014 · Vol. 5, No. 23 · pp. 11847-11856

Keywords: colorectal cancer, heregulin, resistance, cetuximab, patritumab

Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy Research Paper

Wen Wen Xu, Bin Li, Alfred KY Lam, Sai Wah Tsao, Simon YK Law, Kwok Wah Chan, Qiu Ju Yuan, Annie LM Cheung

Published Dec 17, 2014 · Vol. 6, No. 3 · pp. 1790-1805

Keywords: Tumor angiogenesis, Bone marrow-derived cells, Tumor microenvironment, VEGF receptors, Antibody therapy

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Chenchen Wang, Quan Zhou, Xiaofeng Wang, Xiongyan Wu, Xuehua Chen, Jianfang Li, Zhenggang Zhu, Bingya Liu, Liping Su

Published Dec 15, 2014 · Vol. 6, No. 3 · pp. 1779-1789

Keywords: TLR7, Treg cells, Immune suppression, Anti-tumor effect

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

Dong Li, Wenfan Liu, Xuan Wang, Junlu Wu, Wenqiang Quan, Yiwen Yao, Robert Bals, Shurong Ji, Kaiyin Wu, Jia Guo, Haiying Wan

Published Dec 15, 2014 · Vol. 6, No. 5 · pp. 2939-2950

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma Research Paper

Nathaniel Weygant, Dongfeng Qu, Randal May, Ryan M. Tierney, William L. Berry, Lichao Zhao, Shweta Agarwal, Parthasarathy Chandrakesan, Harisha R. Chinthalapally, Nicholas T. Murphy, James D. Li, Sripathi M. Sureban, Michael J. Schlosser, James J. Tomasek, Courtney W. Houchen

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2193-2205

Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer Research Paper

Jinjia Chang, Shanshan Wang, Zhe Zhang, Xinyang Liu, Zheng Wu, Ruixuan Geng, Xiaoxiao Ge, Congqi Dai, Rujiao Liu, Qunling Zhang, Wenhua Li, Jin Li

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2009-2022

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Fangfang Bu, Xing Liu, Jingjing Li, Shukun Chen, Xin Tong, Chunsheng Ma, Hui Mao, Fei Pan, Xiaoyan Li, Bo Chen, Liyan Xu, Enmin Li, Geng Kou, Jun Han, Shangjing Guo, Jian Zhao, Yajun Guo

Published Dec 3, 2014 · Vol. 6, No. 4 · pp. 2120-2133

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype Research Paper

Milone Maria Rita, Pucci Biagio, Bifulco Katia, Iannelli Federica, Lombardi Rita, Chiara Ciardiello, Bruzzese Francesca, Carriero Maria Vincenza, Budillon Alfredo

Published Nov 24, 2014 · Vol. 6, No. 7 · pp. 5324-5341

Keywords: prostate cancer, zoledronic acid, cytoskeleton organization, Î±v integrin, urokinase receptor (uPAR)

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status Research Paper

Zhiguang Xiao, Bianca Sperl, Axel Ullrich, Pjotr Knyazev

Published Nov 2, 2014 · Vol. 5, No. 24 · pp. 12877-12890

Regulation of ERBB3/HER3 signaling in cancer Review

Kalpana Mujoo, Byung-Kwon Choi, Zhao Huang, Ningyan Zhang, Zhiqiang An

Published Nov 2, 2014 · Vol. 5, No. 21 · pp. 10222-10236

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells Research Paper

Annat Raiter, Rinat Yerushalmi, Britta Hardy

Published Oct 24, 2014 · Vol. 5, No. 22 · pp. 11452-11463

Keywords: triple negative breast cancer cells, drug induced cell surface GRP78, apoptosis

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer Research Paper

Julia Femel, Elisabeth J.M. Huijbers, Falk Saupe, Jessica Cedervall, Lei Zhang, Pernilla Roswall, Erik Larsson, Helena Olofsson, Kristian Pietras, Anna Dimberg, Lars Hellman, Anna-Karin Olsson

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12418-12427

Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells Research Paper

Kristian W. Pajtler, Ellen Mahlow, Andrea Odersky, Sven Lindner, Harald Stephan, Ivo Bendix, Angelika Eggert, Alexander Schramm, Johannes H. Schulte

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11180-11192

Maspin expression in prostate tumor elicits host anti-tumor immunity Research Paper

Sijana H. Dzinic, Kang Chen, Archana Thakur, Alexander Kaplun, R. Daniel Bonfil, Xiaohua Li, Jason Liu, M. Margarida Bernardo, Allen Saliganan, Jessica B. Back, Hiroshi Yano, Dana L. Schalk, Elyse N. Tomaszewski, Ahmed S. Beydoun, Gregory Dyson, Adelina Mujagic, David Krass, Ivory Dean, Qing-Sheng Mi, Elisabeth Heath, Wael Sakr, Lawrence G. Lum, Shijie Sheng

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11225-11236

SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/Î²-catenin pathway Research Paper

Xin Tong, Lili Li, Xiaoyan Li, Lei Heng, Lan Zhong, Xianwei Su, Rong Rong, Shi Hu, Wenjia Liu, Baoqing Jia, Xing Liu, Geng Kou, Jun Han, Shangjing Guo, Yi Hu, Cheng Li, Qian Tao, Yajun Guo

Published Sep 25, 2014 · Vol. 5, No. 21 · pp. 10571-10583

Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma Research Paper

Amy Barone, Rajarshi Sengupta, Nicole M. Warrington, Erin Smith, Patrick Y. Wen, Rolf A. Brekken, Barbara Romagnoli, Garry Douglas, Eric Chevalier, Michael P. Bauer, Klaus Dembowsky, David Piwnica-Worms, Joshua B. Rubin

Published Sep 9, 2014 · Vol. 5, No. 20 · pp. 9811-9822

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Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms Research Paper

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy Research Paper

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma Research Paper

Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer Research Paper

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype Research Paper

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status Research Paper

Regulation of ERBB3/HER3 signaling in cancer Review

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells Research Paper

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer Research Paper

Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells Research Paper

Maspin expression in prostate tumor elicits host anti-tumor immunity Research Paper

SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/Î²-catenin pathway Research Paper

Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms Research Paper

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Targeting VEGFR1- and VEGFR2-expressing non-tumor cells is essential for esophageal cancer therapy Research Paper

The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Research Paper

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma Research Paper

Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer Research Paper

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype Research Paper

Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status Research Paper

Regulation of ERBB3/HER3 signaling in cancer Review

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells Research Paper

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer Research Paper

Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells Research Paper

Maspin expression in prostate tumor elicits host anti-tumor immunity Research Paper

SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/Î²-catenin pathway Research Paper

Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma Research Paper