The Oncosearch | Oncotarget

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

Hui Xu, Shervin Rahimpour, Cody L. Nesvick, Xu Zhang, Jingyun Ma, Min Zhang, Ge Zhang, Li Wang, Chunzhang Yang, Christopher S. Hong, Anand V. Germanwala, J. Bradley Elder, Abhik Ray-Chaudhury, Yu Yao, Mark R. Gilbert, Russell R. Lonser, John D. Heiss, Roscoe O. Brady, Ying Mao, Jianhua Qin, Zhengping Zhuang

Published Mar 14, 2015 · Vol. 6, No. 14 · pp. 11882-11893

CD163+ tumor-associated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer patients Clinical Research Papers

Li Yang, Fei Wang, Liping Wang, Lan Huang, Jing Wang, Bin Zhang, Yi Zhang

Published Mar 12, 2015 · Vol. 6, No. 12 · pp. 10592-10603

Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms Research Paper

Jhon A. Ochoa-Alvarez, Harini Krishnan, John G. Pastorino, Evan Nevel, David Kephart, Joseph J. Lee, Edward P. Retzbach, Yongquan Shen, Mahnaz Fatahzadeh, Soly Baredes, Evelyne Kalyoussef, Masaru Honma, Martin E. Adelson, Mika K. Kaneko, Yukinari Kato, Mary Ann Young, Lisa Deluca-Rapone, Alan J. Shienbaum, Kingsley Yin, Lasse D. Jensen, Gary S. Goldberg

Published Mar 10, 2015 · Vol. 6, No. 11 · pp. 9045-9060

Targeting the inhibitory receptor CTLA-4 on T cells increased abscopal effects in murine mesothelioma model Research Paper

Licun Wu, Matthew Onn Wu, Luis De la Maza, Zhihong Yun, Julie Yu, Yidan Zhao, John Cho, Marc de Perrot

Published Mar 8, 2015 · Vol. 6, No. 14 · pp. 12468-12480

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer Research Paper

Igor F. Tsigelny, Jennifer J. Wheler, Jerry P. Greenberg, Valentina L. Kouznetsova, David J. Stewart, Lyudmila Bazhenova, Razelle Kurzrock

Published Feb 28, 2015 · Vol. 6, No. 8 · pp. 6029-6039

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation Research Paper

Alessia Brossa, Cristina Grange, Letizia Mancuso, Laura Annaratone, Maria Antonietta Satolli, Massimiliano Mazzone, Giovanni Camussi, Benedetta Bussolati

Published Feb 28, 2015 · Vol. 6, No. 13 · pp. 11295-11309

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers

Eric Assenat, David Azria, Caroline Mollevi, Rosine Guimbaud, Nicole Tubiana-Mathieu, Denis Smith, Jean-Pierre Delord, Emmanuelle Samalin, Fabienne Portales, Christel Larbouret, Bruno Robert, FrÃ©dÃ©ric Bibeau, Jean-Pierre Bleuse, Evelyne Crapez, Marc Ychou, AndrÃ© PÃ¨legrin

Published Feb 28, 2015 · Vol. 6, No. 14 · pp. 12796-12808

The anti-tumor effect is enhanced by simultaneously targeting VEGF and PROK1 in colorectal cancer Research Paper

Takanori Goi, Toshiyuki Nakazawa, Yasuo Hirono, Akio Yamaguchi

Published Feb 28, 2015 · Vol. 6, No. 8 · pp. 6053-6061

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrinâ€“NF-ÎºBâ€“HIF-1Î± pathway Research Paper

Lei Cao, Xiaoyu Fan, Wei Jing, Yingchao Liang, Rui Chen, Yingying Liu, Minhui Zhu, Rongjie Jia, Hao Wang, Xueguang Zhang, Yanyun Zhang, Xuyu Zhou, Jian Zhao, Yajun Guo

Published Feb 25, 2015 · Vol. 6, No. 9 · pp. 6627-6640

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines Research Paper

Majid Momeny, Jodi M. Saunus, Flavia Marturana, Amy E. McCart Reed, Debra Black, Gianluca Sala, Stefano Iacobelli, Jane D. Holland, Dihua Yu, Leonard Da Silva, Peter T. Simpson, Kum Kum Khanna, Georgia Chenevix-Trench, Sunil R. Lakhani

Published Feb 19, 2015 · Vol. 6, No. 6 · pp. 3932-3946

PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma Review

Jason J. Luke, Patrick A. Ott

Published Feb 17, 2015 · Vol. 6, No. 6 · pp. 3479-3492

Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells Research Paper

Germana Rappa, Toni M. Green, Jana KarbanovÃ¡, Denis Corbeil, Aurelio Lorico

Published Feb 11, 2015 · Vol. 6, No. 10 · pp. 7970-7991

Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer Research Paper

Yiyao Zhang, Li Liu, Pei Fan, Nathalie Bauer, Jury Gladkich, Eduard Ryschich, Alexandr V. Bazhin, Nathalia A. Giese, Oliver Strobel, Thilo Hackert, Ulf Hinz, Wolfgang Gross, Franco Fortunato, Ingrid Herr

Published Feb 5, 2015 · Vol. 6, No. 12 · pp. 9999-10015

Safety and biodistribution of ¹¹¹In-amatuximab in patients with mesothelin expressing cancers using single photon emission computed tomography-computed tomography (SPECT-CT) imaging Clinical Research Papers

Liza Lindenberg, Anish Thomas, Stephen Adler, Esther Mena, Karen Kurdziel, Julia Maltzman, Bruce Wallin, Kimberly Hoffman, Ira Pastan, Chang Hum Paik, Peter Choyke, Raffit Hassan

Published Feb 4, 2015 · Vol. 6, No. 6 · pp. 4496-4504

Keywords: In-Amatuximab, radioimmunoconjugates, mesothelioma, pancreatic cancer, mesothelin

Antibody response to BK polyomavirus as a prognostic biomarker and potential therapeutic target in prostate cancer Clinical Research Papers

Xavier Etienne Keller, Piotr Kardas, Claudio Acevedo, Giovanni Sais, CÃ©dric Poyet, Irina Banzola, Ashkan Mortezavi, Burkhardt Seifert, Tullio Sulser, Hans H. Hirsch, Maurizio Provenzano

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6459-6469

Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

Shi Hu, Yuna Sun, Yanchun Meng, Xiaoze Wang, Weili Yang, Wenyan Fu, Huaizu Guo, Weizhu Qian, Sheng Hou, Bohua Li, Zihe Rao, Zhiyong Lou, Yajun Guo

Published Jan 30, 2015 · Vol. 6, No. 3 · pp. 1695-1706

Keywords: ErbB2, dimerization, signal transduction, crystal structure, Oncogene

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer Research Paper

Isabelle Ader, CÃ©cile Gstalder, Pierre Bouquerel, Muriel Golzio, Guillaume Andrieu, Santiago Zalvidea, Sylvain Richard, Roger A. Sabbadini, Bernard Malavaud, Olivier Cuvillier

Published Jan 29, 2015 · Vol. 6, No. 15 · pp. 13803-13821

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma Research Paper

Sang-Hyun Lee, In Cheul Jeung, Tae Woo Park, Kyungmin Lee, Dong Gwang Lee, Young-Lai Cho, Tae Sup Lee, Hee-Jun Na, Young-Jun Park, Hee Gu Lee, Mun Sik Jeong, Kwang-Hee Bae, Sang Chul Lee, Hyo Jin Lee, Young-Guen Kwon, Hyo Jeong Hong, Jang-Seong Kim, Jeong-Ki Min

Published Jan 22, 2015 · Vol. 6, No. 9 · pp. 7182-7194

Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: A promising biomarker and therapeutic target for pancreatic cancer Research Paper

Donglin Liu, Chien-Hsing Chang, David V. Gold, David M. Goldenberg

Published Jan 19, 2015 · Vol. 6, No. 6 · pp. 4274-4285

Keywords: MUC5AC, epitope mapping, PAM4, pancreatic cancer, cysteine-rich subdomain

CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis Research Paper

Marco Scarpa, Paola Brun, Melania Scarpa, Susan Morgan, Andrea Porzionato, Andromachi Kotsafti, Marina Bortolami, Andrea Buda, Renata Dâ€™IncÃ, Veronica Macchi, Giacomo C. Sturniolo, Massimo Rugge, Romeo Bardini, Ignazio Castagliuolo, Imerio Angriman, Carlo Castoro

Published Jan 19, 2015 · Vol. 6, No. 24 · pp. 20058-20069

Keywords: ulcerative colitis, colorectal carcinogenesis, antigen presenting cells, CD8+ T cells, intestinal epithelial cells

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Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

CD163+ tumor-associated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer patients Clinical Research Papers

Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms Research Paper

Targeting the inhibitory receptor CTLA-4 on T cells increased abscopal effects in murine mesothelioma model Research Paper

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer Research Paper

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation Research Paper

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers

The anti-tumor effect is enhanced by simultaneously targeting VEGF and PROK1 in colorectal cancer Research Paper

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrinâ€“NF-ÎºBâ€“HIF-1Î± pathway Research Paper

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines Research Paper

PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma Review

Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells Research Paper

Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer Research Paper

Safety and biodistribution of ¹¹¹In-amatuximab in patients with mesothelin expressing cancers using single photon emission computed tomography-computed tomography (SPECT-CT) imaging Clinical Research Papers

Antibody response to BK polyomavirus as a prognostic biomarker and potential therapeutic target in prostate cancer Clinical Research Papers

Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer Research Paper

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma Research Paper

Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: A promising biomarker and therapeutic target for pancreatic cancer Research Paper

CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

CD163+ tumor-associated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer patients Clinical Research Papers

Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms Research Paper

Targeting the inhibitory receptor CTLA-4 on T cells increased abscopal effects in murine mesothelioma model Research Paper

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer Research Paper

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation Research Paper

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers

The anti-tumor effect is enhanced by simultaneously targeting VEGF and PROK1 in colorectal cancer Research Paper

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrinâ€“NF-ÎºBâ€“HIF-1Î± pathway Research Paper

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines Research Paper

PD-1 pathway inhibitors: The next generation of immunotherapy for advanced melanoma Review

Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells Research Paper

Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer Research Paper

Safety and biodistribution of 111In-amatuximab in patients with mesothelin expressing cancers using single photon emission computed tomography-computed tomography (SPECT-CT) imaging Clinical Research Papers

Antibody response to BK polyomavirus as a prognostic biomarker and potential therapeutic target in prostate cancer Clinical Research Papers

Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer Research Paper

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma Research Paper

Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: A promising biomarker and therapeutic target for pancreatic cancer Research Paper

CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis Research Paper

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the â€œTHERAPYâ€phase 1-2 trial Clinical Research Papers

Safety and biodistribution of ¹¹¹In-amatuximab in patients with mesothelin expressing cancers using single photon emission computed tomography-computed tomography (SPECT-CT) imaging Clinical Research Papers