The Oncosearch | Oncotarget

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Apr 16, 2020 · Vol. 11, No. 19 · pp. 1691-1704

Keywords: PPP1R1A, cell cycle control, IGF-1R, metastasis, Ewing sarcoma

Lack of CD8⁺ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper

Salum J. Lidenge, For Yue Tso, Owen Ngalamika, Jaydeep Kolape, John R. Ngowi, Julius Mwaiselage, Charles Wood, John T. West

Published Apr 16, 2020 · Vol. 11, No. 17 · pp. 1556-1572

Keywords: Kaposi’s sarcoma, HIV-1, KSHV, immune cells, tumor microenvironment

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Gilseung Park, Jessica Burroughs-Garcia, Clay A. Foster, Ameera Hasan, Chiara Borga, J. Kimble Frazer

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1292-1305

Keywords: acute lymphoblastic leukemia, ALL, zebrafish, lymphocyte, MYC

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Indu Kohaar, Qiyuan Li, Yongmei Chen, Lakshmi Ravindranath, Denise Young, Amina Ali, Isabell A. Sesterhenn, Inger L. Rosner, Jennifer Cullen, Shiv Srivastava, Matthew Freedman, Gyorgy Petrovics

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1321-1333

Keywords: prostate cancer, TMPRSS2-ERG, molecular subtype, ERG fusion, SNP

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Vijay R. Gupta, Adam Root, Timothy Fisher, Rand Norberg, John David, Tracey Clark, Justin Cohen, Chad May, Anand Giddabasappa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1344-1357

Keywords: bispecific antibody, tumor targeting, biodistribution, T cells, molecular imaging

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Marina P. Antoch, Michelle Wrobel, Bryan Gillard, Karen K. Kuropatwinski, Ilia Toshkov, Anatoli S. Gleiberman, Ellen Karasik, Michael T. Moser, Barbara A. Foster, Ekaterina L. Andrianova, Olga V. Chernova, Andrei V. Gudkov

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1373-1387

Keywords: prostate cancer, rapamycin, prevention, mTOR, PTEN

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Beatriz Ballester, Javier Milara, Julio Cortijo

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1306-1320

Keywords: pirfenidone, idiopathic pulmonary fibrosis, MUC1, transforming growth factor beta-1, fibroblasts

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Vaishali Kapoor, Andrea Collins, Kaylan Griffith, Subhajit Ghosh, Nathan Wong, Xiaowei Wang, Grant A. Challen, Joseph Krambs, Dan Link, Dennis E. Hallahan, Dinesh Thotala

Published Apr 13, 2020 · Vol. 11, No. 19 · pp. 1681-1690

Keywords: radiation, lymphopenia, mass cytometry RNA sequencing

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Natalia V. Eremina, Vasily I. Kazey, Sergey V. Mishugin, Roman V. Leonenkov, Dmitry Y. Pushkar, Vadim L. Mett, Andrei V. Gudkov

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1273-1288

Keywords: prostate cancer, immunotherapy, mobilan, adenoviral vector, intratumor injection

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

David J. Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1257-1272

Keywords: SYK inhibitor, breast carcinoma, 3D culture, murine mammary gland, proliferation

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Moran Mazuz, Amir Tiroler, Lilach Moyal, Emmilia Hodak, Stalin Nadarajan, Ajjampura C. Vinayaka, Batia Gorovitz-Haris, Ido Lubin, Avi Drori, Guy Drori, Owen Van Cauwenberghe, Adi Faigenboim, Dvora Namdar, Iris Amitay-Laish, Hinanit Koltai

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1141-1156

Keywords: cutaneous T-cell lymphoma, cannabis, cannabinoids, peripheral blood lymphocytes, CTCL cell lines

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Betul Gok Yavuz, Roberto Carmagnani Pestana, Yehia I. Abugabal, Sunil Krishnan, Jian Chen, Manal M. Hassan, Robert A. Wolff, Asif Rashid, Hesham M. Amin, Ahmed O. Kaseb

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1186-1201

Keywords: hepatocellular carcinoma, stellate cells, myofibroblasts, liver fibrosis, immunotherapy

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Giseli Mitsuy Kayahara, Vitor Bonetti Valente, Rosani Belzunces Pereira, Felipe Yudi Kabeya Lopes, Marcelo Macedo Crivelini, Glauco Issamu Miyahara, Éder Ricardo Biasoli, Sandra Helena Penha Oliveira, Daniel Galera Bernabé

Published Mar 28, 2020 · Vol. 11, No. 20 · pp. 1816-1831

Keywords: melatonin, cancer, oral cancer, carcinogenesis, pineal gland

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

John M. Idso, Shunhua Lao, Nathan J. Schloemer, Jeffrey Knipstein, Robert Burns, Monica S. Thakar, Subramaniam Malarkannan

Published Mar 25, 2020 · Vol. 11, No. 20 · pp. 1799-1815

Keywords: NK cells, histone deacetylase inhibitor, Ewing sarcoma, rhabdomyosarcoma, immunotherapy

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Souhila Abdelfettah, Gaylor Boulay, Marion Dubuissez, Nathalie Spruyt, Sara P. Garcia, Shruthi Rengarajan, Ingrid Loison, Xavier Leroy, Miguel N. Rivera, Dominique Leprince

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1051-1074

Keywords: hPCL3S, PHF19, PRC2, β-catenin, prostate cancer

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Lacey M. Litchfield, Karsten Boehnke, Manisha Brahmachary, Cecilia Mur, Chen Bi, Jennifer R. Stephens, J. Michael Sauder, Sonia M. Gutiérrez, Ann M. McNulty, Xiang S. Ye, Wenjuan Wu, María José Lallena, Xueqian Gong, Farhana F. Merzoug, Valerie M. Jansen, Sean G. Buchanan

Published Mar 23, 2020 · Vol. 11, No. 17 · pp. 1478-1492

Keywords: abemaciclib, CDK4/6, PIM, mTOR, S6

Acute promyelocytic leukemia (APL): a review of the literature Review

Joaquin J. Jimenez, Ravinder S. Chale, Andrea C. Abad, Andrew V. Schally

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 992-1003

Keywords: promyelocytic leukemia, arsenic trioxide, retinoic acid, resistance

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Caroline Dafflon, Swann Gaulis, Louise Barys, Karen Kapur, Vanessa Cornacchione, Lina Schukur, Sebastian Bergling, Elisabetta Traggiai, Selina Jansky, Leon Hellmann, Barbara Schacher Engstler, Grainne Kerr, Antoine de Weck, David A. Ruddy, Ulrike Naumann, Frédéric Stauffer, Christoph Gaul, Ying Lin, Eric Billy, Andreas Weiss, Francesco Hofmann, Moriko Ito, Ralph Tiedt

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 956-968

Keywords: DOT1L, multiple myeloma, epigenetics, histone methylation, unfolded protein response

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Lack of CD8⁺ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Lack of CD8+ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Lack of CD8⁺ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors Research Paper