The Oncosearch | Oncotarget

The multifaceted anti-cancer effects of BRAF-inhibitors Review

Laura Croce, Francesca Coperchini, Flavia Magri, Luca Chiovato, Mario Rotondi

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6623-6640

Keywords: BRAF, BRAF-inhibitors, tumor microenvironment, chemokines, CXCL8

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

Douglas Jury, Iben Daugaard, Katie J. Sanders, Lise Lotte Hansen, Dritan Agalliu, Irene Munk Pedersen

Published Nov 7, 2019 · Vol. 11, No. 23 · pp. 2160-2171

Keywords: angiogenesis, miR-151a, Slug, tumor microenvironment, endothelial cell

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

David King, Xiao Dun Li, Gilberto S. Almeida, Colin Kwok, Polly Gravells, Daniel Harrison, Saoirse Burke, Albert Hallsworth, Yann Jamin, Sally George, Simon P. Robinson, Christopher J. Lord, Evon Poon, Daniel Yeomanson, Louis Chesler, Helen E. Bryant

Published Nov 6, 2019 · Vol. 11, No. 23 · pp. 2141-2159

Keywords: PARP inhibitor, neuroblastoma, MYCN, replication stress, replication fork stalling

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Fillipe Luiz Rosa do Carmo, Houem Rabah, Barbara Fernandes Cordeiro, Sara Heloisa da Silva, Rafaela Miranda Pessoa, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Valérie Gagnaire, Martine Deplanche, Bruna Savassi, Alessandra Figueiroa, Emiliano Rosa Oliveira, Caio César Fonseca, Maria Izabel Alves Queiroz, Núbia Morais Rodrigues, Sávio Henrique de Cicco Sandes, Álvaro Cantini Nunes, Luisa Lemos, Juliana de Lima Alves, Ana Maria Caetano Faria, Ênio Ferreira, Yves Le Loir, Gwénaël Jan, Vasco Azevedo

Published Nov 5, 2019

Keywords: mucositis, probiotic, surface protein, immunomodulation, inflammation

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Albert D. Donnenberg, James D. Luketich, Vera S. Donnenberg

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6456-6465

Keywords: pleural effusion, non-small cell lung cancer, malignant mesothelioma, cytokines, IL-6

Volasertib preclinical activity in high-risk hepatoblastoma Research Paper

Dina Kats, Cora A. Ricker, Noah E. Berlow, Bénédicte Noblet, Delphine Nicolle, Katell Mevel, Sophie Branchereau, Jean-Gabriel Judde, Cody D. Stiverson, Christina L. Stiverson, Matthew N. Svalina, Teagan Settelmeyer, Kevin Matlock, Melvin Lathara, Charlotte Mussini, James I. Geller, Christopher Noakes, Ido Sloma, Narendra Bharathy, Stefano Cairo, Charles Keller

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6403-6417

Keywords: hepatoblastoma, PLK1, volasertib, liver, cell cycle

Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts Research Paper

Emily Marie Mangialardi, Keyue Chen, Brittany Salmon, Jean Vacher, Leonardo Salmena

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6378-6390

Keywords: Inpp4b, MEF, RAS, E1A, SV40-T-Large

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Andrew J. Sanders, Sioned Owen, Liam D. Morgan, Fiona Ruge, Ross J. Collins, Lin Ye, Malcolm D. Mason, Wen G. Jiang

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6362-6377

Keywords: ALCAM, prostate cancer, bone, metastasis, serum biomarker

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience Research Paper

Michael Merker, Michael Torsten Meister, Annekathrin Heinze, Andrea Jarisch, Jan Sörensen, Sabine Huenecke, Melanie Bremm, Claudia Cappel, Thomas Klingebiel, Peter Bader, Eva Rettinger

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6138-6151

Keywords: adoptive cellular immunotherapy, allogeneic, solid tumors, childhood, HSCT

Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma Research Paper

Lasse Dührsen, Sophie Hartfuß, Daniela Hirsch, Sabine Geiger, Cecile L. Maire, Jan Sedlacik, Christine Guenther, Manfred Westphal, Katrin Lamszus, Felix G. Hermann, Nils Ole Schmidt

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6049-6061

Keywords: glioblastoma, brain tumor, stem cells, gene therapy, migration

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Hwudaurw Chen, Earlphia Sells, Ritu Pandey, Edward R. Abril, Chiu-Hsieh Hsu, Robert S. Krouse, Raymond B. Nagle, Georgios Pampalakis, Georgia Sotiropoulou, Natalia A. Ignatenko

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6062-6078

Keywords: colorectal cancer, kallikrein-related peptidase 6 or KLK6, SMAD2/3, epithelial-mesenchymal transition, HMGA2

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Tatsuya Kawase, Taisuke Nakazawa, Tomohiro Eguchi, Hirofumi Tsuzuki, Yoko Ueno, Yasushi Amano, Tomoyuki Suzuki, Masamichi Mori, Taku Yoshida

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6111-6123

Keywords: FLT3, FL, FLT3 inhibitor, gilteritinib, antitumor activity

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC Correction

Zi Wang, Bianyin Ma, Hui Li, Xiaojuan Xiao, Weihua Zhou, Feng Liu, Bin Zhang, Min Zhu, Qin Yang, Yayue Zeng, Yang Sun, Shuming Sun, Yanpeng Wang, Yibin Zhang, Haibo Weng, Lixiang Chen, Mao Ye, Xiuli An, Jing Liu

Published Oct 15, 2019 · Vol. 10, No. 58 · pp. 6285-6285

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC Correction

Zi Wang, Bianyin Ma, Hui Li, Xiaojuan Xiao, Weihua Zhou, Feng Liu, Bin Zhang, Min Zhu, Qin Yang, Yayue Zeng, Yang Sun, Shuming Sun, Yanpeng Wang, Yibin Zhang, Haibo Weng, Lixiang Chen, Mao Ye, Xiuli An, Jing Liu

Published Oct 15, 2019

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Qiang Qiu, Mengyuan Li, Linyu Yang, Minghai Tang, Li Zheng, Fang Wang, Huandi Qiu, Cailing Liang, Ning Li, Dongni Yi, Yuyao Yi, Cong Pan, Shengyong Yang, Lijuan Chen, Yiguo Hu

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5993-6005

Keywords: glutaminase1, multiple myeloma, BPTES, cMYC/KRAS12V-transduced plasmacytoma, mouse model

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Prachi Namjoshi, Lori Showalter, Brian J. Czerniecki, Gary K. Koski

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 6006-6020

Keywords: apoptosis, HER-2, T-helper 1, IFN-γ, TNF-α

Assessment of circularized E7 RNA, GLUT1, and PD-L1 in anal squamous cell carcinoma Research Paper

Bahir H. Chamseddin, Eunice E. Lee, Jiwoong Kim, Xiaowei Zhan, Rong Yang, Kathleen M. Murphy, Cheryl Lewis, Gregory A. Hosler, Suntrea T. Hammer, Richard C. Wang

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5958-5969

Keywords: anal squamous cell carcinoma, circular RNA, GLUT1, human papillomavirus, PD-L1

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

Yosuke Ooizumi, Hiroshi Katoh, Mitsuo Yokota, Masahiko Watanabe, Keishi Yamashita

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5906-5918

Keywords: HOPX, papillary thyroid cancer, epigenetic silencing, promoter methylation

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

Shiho Fukui, Kazunori Nagasaka, Yuko Miyagawa, Ryoko Kikuchi-Koike, Yoshiko Kawata, Ranka Kanda, Takayuki Ichinose, Takeru Sugihara, Haruko Hiraike, Osamu Wada-Hiraike, Yuko Sasajima, Takuya Ayabe

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5932-5948

Keywords: ovarian cancer, bAP15, TGF-β/Smad signaling, UCHL5, apoptosis

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

Nikhil Gupta, Jung Eun Park, Wilford Tse, Jee Keem Low, Oi Lian Kon, Neil McCarthy, Siu Kwan Sze

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5970-5982

Keywords: pancreatic cancer, hypoxia tumor, ERO1α, SILAC, proteomics

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The multifaceted anti-cancer effects of BRAF-inhibitors Review

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Volasertib preclinical activity in high-risk hepatoblastoma Research Paper

Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience Research Paper

Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC Correction

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC Correction

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Assessment of circularized E7 RNA, GLUT1, and PD-L1 in anal squamous cell carcinoma Research Paper

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The multifaceted anti-cancer effects of BRAF-inhibitors Review

miR-151a enhances Slug dependent angiogenesis Priority Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Probiotic propionibacterium freudenreichii requires SlpB protein to mitigate mucositis induced by chemotherapy Research Paper

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications Research Paper

Volasertib preclinical activity in high-risk hepatoblastoma Research Paper

Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts Research Paper

Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination Research Paper

Adoptive cellular immunotherapy for refractory childhood cancers: a single center experience Research Paper

Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC Correction

Correction: Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC Correction

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells Research Paper

Assessment of circularized E7 RNA, GLUT1, and PD-L1 in anal squamous cell carcinoma Research Paper

Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer Research Paper

The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer Research Paper

ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer Research Paper