The Oncosearch | Oncotarget

KRAS, NRAS and BRAF mutations detected by next generation sequencing, and differential clinical outcome in metastatic colorectal cancer (MCRC) patients treated with first line FIr-B/FOx adding bevacizumab (BEV) to triplet chemotherapy Research Paper

Gemma Bruera, Francesco Pepe, Umberto Malapelle, Pasquale Pisapia, Antonella Dal Mas, Daniela Di Giacomo, Giuseppe Calvisi, Giancarlo Troncone, Enrico Ricevuto

Published May 29, 2018 · Vol. 9, No. 41 · pp. 26279-26290

Potentiation of ¹⁷⁷Lu-octreotate peptide receptor radionuclide therapy of human neuroendocrine tumor cells by PARP inhibitor Research Paper

Nupur K. Purohit, Rashmi G. Shah, Samuel Adant, Michael Hoepfner, Girish M. Shah, Jean-Mathieu Beauregard

Published May 15, 2018 · Vol. 9, No. 37 · pp. 24693-24706

Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma Research Paper

Jian Yu, Yun Chen, Liguang Chen, Ling Zhang, Laura Z. Rassenti, George F. Widhopf II, Thomas J. Kipps

Published May 15, 2018 · Vol. 9, No. 37 · pp. 24731-24736

Identification of RECK as an evolutionarily conserved tumor suppressor gene for zebrafish malignant peripheral nerve sheath tumors Research Paper

Rashmi Kumari, Martin R. Silic, Yava L. Jones-Hall, Alexandra Nin-Velez, Jer-Yen Yang, Suresh K. Mittal, GuangJun Zhang

Published May 4, 2018 · Vol. 9, No. 34 · pp. 23494-23504

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors Research Paper

Elizaveta E. Alemasova, Konstantin N. Naumenko, Tatyana A. Kurgina, Rashid O. Anarbaev, Olga I. Lavrik

Published May 4, 2018 · Vol. 9, No. 34 · pp. 23349-23365

Correction: Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation Correction

Audrey Bettoun, Carine Joffre, Giulia Zago, Didier Surdez, David Vallerand, Ramazan Gundogdu, Ahmad A.D. Sharif, Marta Gomez, Ilaria Cascone, Brigitte Meunier, Michael A. White, Patrice Codogno, Maria Carla Parrini, Jacques H. Camonis, Alexander Hergovich

Published Apr 27, 2018 · Vol. 9, No. 32 · pp. 22870-22870

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors Research Paper

Elliot John Kahen, Andrew Brohl, Diana Yu, Darcy Welch, Christopher L. Cubitt, Jae K. Lee, Yunyun Chen, Sean J. Yoder, Jamie K. Teer, Yonghong O. Zhang, Margaret R. Wallace, Damon R. Reed

Published Apr 27, 2018 · Vol. 9, No. 32 · pp. 22571-22585

FSH receptor binding inhibitor impacts K-Ras and c-Myc of ovarian cancer and signal pathway Research Paper

Suocheng Wei, Xiaoyun Shen, Luju Lai, Haoqin Liang, Yingying Deng, Zhuandi Gong, Tuanjie Che

Published Apr 27, 2018 · Vol. 9, No. 32 · pp. 22498-22508

An improved method for culturing patient-derived colorectal cancer spheroids Research Paper

Hiroyuki Miyoshi, Hisatsugu Maekawa, Fumihiko Kakizaki, Tadayoshi Yamaura, Kenji Kawada, Yoshiharu Sakai, M. Mark Taketo

Published Apr 24, 2018 · Vol. 9, No. 31 · pp. 21950-21964

Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients Research Paper

Maria Rosaria Ricciardi, Valentina Salvestrini, Roberto Licchetta, Simone Mirabilii, Mattia Forcato, Gabriele Gugliotta, Simona Salati, Fausto Castagnetti, Gianantonio Rosti, Massimo Breccia, Giuliana Alimena, Rossella Manfredini, Silvio Bicciato, Roberto Massimo Lemoli, Agostino Tafuri

Published Apr 24, 2018 · Vol. 9, No. 31 · pp. 21758-21769

Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice Research Paper

Stefan P. Tarnawsky, Wen-Mei Yu, Cheng-Kui Qu, Rebecca J. Chan, Mervin C. Yoder

Published Apr 24, 2018 · Vol. 9, No. 31 · pp. 21831-21843

SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways Research Paper

Neslihan Zohrap, Ã–zge Saatci, Burcak Ozes, Ipek Coban, Hasan Murat Atay, Esra Battaloglu, Ã–zgÃ¼r Åžahin, Kuyas Bugra

Published Apr 24, 2018 · Vol. 9, No. 31 · pp. 21876-21892

Cross-platform comparison for the detection of RAS mutations in cfDNA (ddPCR Biorad detection assay, BEAMing assay, and NGS strategy) Research Paper

Jessica Garcia, Julien Forestier, Eric Dusserre, Anne-Sophie Wozny, Florence Geiguer, Patrick Merle, Claire Tissot, Carole Ferraro-Peyret, Frederick S. Jones, Daniel L. Edelstein, ValÃ©rie Cheynet, Claire Bardel, Gaelle Vilchez, Zhenyu Xu, Pierre Paul Bringuier, Marc Barritault, Karen Brengle-Pesce, Marielle Guillet, Marion Chauvenet, Brigitte Manship, Marie Brevet, Claire Rodriguez-Lafrasse, ValÃ©rie Hervieu, SÃ©bastien Couraud, Thomas Walter, LÃ©a Payen

Published Apr 20, 2018 · Vol. 9, No. 30 · pp. 21122-21131

Signature program: a platform of basket trials Research Paper

Eric D. Slosberg, Barinder P. Kang, Julio Peguero, Matthew Taylor, Todd M. Bauer, Donald A. Berry, Fadi Braiteh, Alexander Spira, Funda Meric-Bernstam, Steven Stein, Sarina A. Piha-Paul, August Salvado

Published Apr 20, 2018 · Vol. 9, No. 30 · pp. 21383-21395

Systemic inflammatory status predict the outcome of k-RAS WT metastatic colorectal cancer patients receiving the thymidylate synthase poly-epitope-peptide anticancer vaccine Research Paper

Pierpaolo Correale, Cirino Botta, Nicoletta Staropoli, Valerio Nardone, Pierpaolo Pastina, Cristina Ulivieri, Claudia Gandolfo, Tatiana Cosima Baldari, Stefano Lazzi, Domenico Ciliberto, Rocco Giannicola, Antonella Fioravanti, Antonio Giordano, Silvia Zappavigna, Michele Caraglia, Pierfrancesco Tassone, Luigi Pirtoli, Maria Grazia Cusi, Pierosandro Tagliaferri

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20539-20554

Sequential immunotherapy in a patient with primary refractory Hodgkin lymphoma and novel mutations Case Report

Richard Greil, Lisa Pleyer, Bettina Jansko, Carmen Feierabend, Lukas Rettenbacher, Olga Stiefel, Christoph Rass, Patrick Morre, Daniel Neureiter, Sigrun Greil-Ressler

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20928-20940

Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience Research Paper

Nicky Dâ€™Haene, Quitterie Fontanges, Nancy De NÃ¨ve, Oriane Blanchard, Barbara Melendez, Monique Delos, Marie-FranÃ§oise Dehou, Calliope Maris, Nathalie Nagy, Emmanuel Rousseau, Josse Vandenhove, AndrÃ© Gilles, Carine De Prez, Laurine Verset, Marie-Paule Van Craynest, Pieter Demetter, Jean-Luc Van Laethem, Isabelle Salmon, Marie Le Mercier

Published Apr 17, 2018 · Vol. 9, No. 29 · pp. 20761-20768

Mouse genetic background influences whether Hras^G12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper

Laura P. Brandt, Joachim Albers, Tomas Hejhal, Svende Pfundstein, Ana Filipa GonÃ§alves, Antonella Catalano, Peter J. Wild, Ian J. Frew

Published Apr 13, 2018 · Vol. 9, No. 28 · pp. 19753-19766

Gene-specific methylation profiles in BRCA-mutation positive and BRCA-mutation negative male breast cancers Research Paper

Piera Rizzolo, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Ines Zanna, Giovanna Masala, Simonetta Bianchi, Domenico Palli, Laura Ottini

Published Apr 13, 2018 · Vol. 9, No. 28 · pp. 19783-19792

A phase II trial of 1st-line modified-FOLFOXIRI plus bevacizumab treatment for metastatic colorectal cancer harboring RAS mutation: JACCRO CC-11 Research Paper

Hironaga Satake, Yu Sunakawa, Yuji Miyamoto, Masato Nakamura, Hiroshi Nakayama, Manabu Shiozawa, Akitaka Makiyama, Kazuma Kobayashi, Yutaro Kubota, Misuzu Mori, Masahito Kotaka, Akinori Takagane, Masahiro Gotoh, Masahiro Takeuchi, Masashi Fujii, Wararu Ichikawa, Takashi Sekikawa

Published Apr 10, 2018 · Vol. 9, No. 27 · pp. 18811-18820

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KRAS, NRAS and BRAF mutations detected by next generation sequencing, and differential clinical outcome in metastatic colorectal cancer (MCRC) patients treated with first line FIr-B/FOx adding bevacizumab (BEV) to triplet chemotherapy Research Paper

Potentiation of ¹⁷⁷Lu-octreotate peptide receptor radionuclide therapy of human neuroendocrine tumor cells by PARP inhibitor Research Paper

Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma Research Paper

Identification of RECK as an evolutionarily conserved tumor suppressor gene for zebrafish malignant peripheral nerve sheath tumors Research Paper

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors Research Paper

Correction: Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation Correction

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors Research Paper

FSH receptor binding inhibitor impacts K-Ras and c-Myc of ovarian cancer and signal pathway Research Paper

An improved method for culturing patient-derived colorectal cancer spheroids Research Paper

Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients Research Paper

Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice Research Paper

SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways Research Paper

Cross-platform comparison for the detection of RAS mutations in cfDNA (ddPCR Biorad detection assay, BEAMing assay, and NGS strategy) Research Paper

Signature program: a platform of basket trials Research Paper

Systemic inflammatory status predict the outcome of k-RAS WT metastatic colorectal cancer patients receiving the thymidylate synthase poly-epitope-peptide anticancer vaccine Research Paper

Sequential immunotherapy in a patient with primary refractory Hodgkin lymphoma and novel mutations Case Report

Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience Research Paper

Mouse genetic background influences whether Hras^G12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper

Gene-specific methylation profiles in BRCA-mutation positive and BRCA-mutation negative male breast cancers Research Paper

A phase II trial of 1st-line modified-FOLFOXIRI plus bevacizumab treatment for metastatic colorectal cancer harboring RAS mutation: JACCRO CC-11 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

KRAS, NRAS and BRAF mutations detected by next generation sequencing, and differential clinical outcome in metastatic colorectal cancer (MCRC) patients treated with first line FIr-B/FOx adding bevacizumab (BEV) to triplet chemotherapy Research Paper

Potentiation of 177Lu-octreotate peptide receptor radionuclide therapy of human neuroendocrine tumor cells by PARP inhibitor Research Paper

Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma Research Paper

Identification of RECK as an evolutionarily conserved tumor suppressor gene for zebrafish malignant peripheral nerve sheath tumors Research Paper

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors Research Paper

Correction: Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation Correction

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors Research Paper

FSH receptor binding inhibitor impacts K-Ras and c-Myc of ovarian cancer and signal pathway Research Paper

An improved method for culturing patient-derived colorectal cancer spheroids Research Paper

Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients Research Paper

Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice Research Paper

SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways Research Paper

Cross-platform comparison for the detection of RAS mutations in cfDNA (ddPCR Biorad detection assay, BEAMing assay, and NGS strategy) Research Paper

Signature program: a platform of basket trials Research Paper

Systemic inflammatory status predict the outcome of k-RAS WT metastatic colorectal cancer patients receiving the thymidylate synthase poly-epitope-peptide anticancer vaccine Research Paper

Sequential immunotherapy in a patient with primary refractory Hodgkin lymphoma and novel mutations Case Report

Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience Research Paper

Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper

Gene-specific methylation profiles in BRCA-mutation positive and BRCA-mutation negative male breast cancers Research Paper

A phase II trial of 1st-line modified-FOLFOXIRI plus bevacizumab treatment for metastatic colorectal cancer harboring RAS mutation: JACCRO CC-11 Research Paper

Potentiation of ¹⁷⁷Lu-octreotate peptide receptor radionuclide therapy of human neuroendocrine tumor cells by PARP inhibitor Research Paper

Mouse genetic background influences whether Hras^G12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma Research Paper