The Oncosearch | Oncotarget

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment Research Paper

Valentin Feichtenschlager, Yixuan James Zheng, Wilson Ho, Linan Chen, Ciara Callanan, Christopher Chen, Albert Lee, Jose Ortiz, Klemens Rappersberger, Susana Ortiz-Urda

Published May 19, 2023 · Vol. 14, No. 1 · pp. 543-560

Keywords: MALAT1, MAPK-pathway, BRAF, melanoma, antisense oligonucleotides

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Nada Tawfeeq, Jassy Mary S. Lazarte, Yonghao Jin, Matthew D. Gregory, Nazarius S. Lamango

Published Mar 15, 2023 · Vol. 14, No. 1 · pp. 243-257

Keywords: PCAIs, G-proteins, KRAS, RHOA, RAC1

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Yehia I. Mohamed, Dan G. Duda, Muhammad O. Awiwi, Sunyoung S. Lee, Lina Altameemi, Lianchun Xiao, Jeffrey S. Morris, Robert A. Wolff, Khaled M. Elsayes, Rikita I. Hatia, Aliya Qayyum, Shadi M. Chamseddine, Asif Rashid, James C. Yao, Armeen Mahvash, Manal M. Hassan, Hesham M. Amin, Ahmed Omar Kaseb

Published Nov 26, 2022 · Vol. 13, No. 1 · pp. 1314-1321

Keywords: growth hormone, hepatocellular carcinoma, immunotherapy, atezolizumab, bevacizumab

Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors Research Paper

Andliena Tahiri, Katarina Puco, Faris Naji, Vessela N. Kristensen, Glenny Cecilie Alfsen, Lorant Farkas, Frode S. Nilsen, Stig Müller, Jan Oldenburg, Jürgen Geisler

Published Jul 8, 2022 · Vol. 13, No. 1 · pp. 970-981

Keywords: kidney cancer, kinase activity, tyrosine kinase inhibitors, renal cell carcinoma, tyrosine kinase

Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast Research Paper

Anna Leonov, Rachel Feldman, Amanda Piano, Anthony Arlia-Ciommo, Jennifer Anne Baratang Junio, Emmanuel Orfanos, Tala Tafakori, Vicky Lutchman, Karamat Mohammad, Sarah Elsaser, Sandra Orfali, Harshvardhan Rajen, Vladimir I. Titorenko

Published Jul 6, 2022 · Vol. 13, No. 1 · pp. 918-943

Keywords: cellular aging, cellular quiescence, longevity, gerotargets, geroprotectors

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer Review

Alexander W. Pohlman, Hita Moudgalya, Lia Jordano, Gabriela C. Lobato, David Gerard, Michael J. Liptay, Christopher W. Seder, Jeffrey A. Borgia

Published Feb 15, 2022 · Vol. 13, No. 1 · pp. 393-407

Keywords: IGF, lung cancer, biomarkers, screening, prognostication

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Krishma Tailor, Joseph Paul, Somiranjan Ghosh, Namita Kumari, Bernard Kwabi-Addo

Published Dec 15, 2021 · Vol. 12, No. 26 · pp. 2489-2499

Keywords: RASAL2, Ras-protooncogene, prostate cancer, TNFα signal, DNA methylation

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Monica Sharma, Isabel Castro-Piedras, Fahmida Rasha, Sabarish Ramachandran, Souad R. Sennoune, Kathryn Furr, Sharilyn Almodovar, Vadivel Ganapathy, Matthew B. Grisham, Rakhshanda Layeequr Rahman, Kevin Pruitt

Published Sep 28, 2021 · Vol. 12, No. 22 · pp. 2234-2251

Keywords: dishevelled (DVL), post-translational modification, lysine residue, gene expression, chromatin immunoprecipitation (ChIP)

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Jan A. Kaczmarczyk, Rhonda R. Roberts, Brian T. Luke, King C. Chan, Carly M. Van Wagoner, Robin A. Felder, Richard G. Saul, Colantonio Simona, Josip Blonder

Published Sep 3, 2021 · Vol. 12, No. 20 · pp. 2022-2038

Keywords: lung cancer, proteomics, 2D vs. 3D cultured cells, preclinical testing model, drug target discovery

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Mario Scarpa, Shivani Kapoor, Eric S. Tvedte, Kshama A. Doshi, Ying S. Zou, Prerna Singh, Jonelle K. Lee, Aditi Chatterjee, Moaath K. Mustafa Ali, Robin E. Bromley, Julie C. Dunning Hotopp, Feyruz V. Rassool, Maria R. Baer

Published Aug 2, 2021 · Vol. 12, No. 18 · pp. 1763-1779

Keywords: FLT3 internal tandem duplication, Pim kinase, alternative non-homologous end-joining DNA repair, genomic instability, topoisomerase 2 inhibitors

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

Maria Grazia Vizioli, Joana Santos, Silvana Pilotti, Mara Mazzoni, Maria Chiara Anania, Claudia Miranda, Sonia Pagliardini, Marco A. Pierotti, Jesus Gil, Angela Greco

Published Jul 2, 2021 · Vol. 13, No. 1 · pp. 1120-1121

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Pareesa Kamgar-Dayhoff, Tinatin I. Brelidze

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1406-1426

Keywords: chlorpromazine, repurposing

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Austin R. Dosch, Walid K. Chatila, Yuguang Ban, Anna Bianchi, Nilesh U. Deshpande, Iago De Castro Silva, Nipun B. Merchant, Jashodeep Datta

Published Jun 1, 2021 · Vol. 12, No. 20 · pp. 2104-2110

Keywords: Ras-p53 cooperativity, Ras, TP53, immune, gastrointestinal cancer

Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab Research Paper

Samantha Epistolio, Marco Cefalì, Paolo Spina, Francesca Molinari, Alessandra Movilia, Massimiliano Cergnul, Luca Mazzucchelli, Sara De Dosso, Milo Frattini, Piercarlo Saletti

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1046-1056

Keywords: RAS mutations, bevacizumab, metastatic colorectal cancer, next-generation sequencing

CEA as a blood-based biomarker in anal cancer Research Paper

Robert Hester, Shailesh Advani, Asif Rashid, Emma Holliday, Craig Messick, Prajnan Das, Yi-Qian N. You, Cullen Taniguchi, Eugene J. Koay, Brian Bednarski, Miguel Rodriguez-Bigas, John Skibber, Robert Wolff, George J. Chang, Bruce D. Minsky, Wai Chin Foo, Nicole Rothschild, Van K. Morris, Cathy Eng

Published May 5, 2021 · Vol. 12, No. 11 · pp. 1037-1045

Keywords: carcinoembryonic antigen, squamous cell carcinoma of anal canal, anal cancer, biomarkers, HPV

Association between miRNA signatures in serum samples from epidermal growth factor inhibitor treated patients and skin toxicity Research Paper

Sarah Kemski, Vivien Molitor, Michael Steffens, Tim J. Nümm, Nadine Herrmann, Thorsten Hornung, Thomas Bieber, Christian Schumann, Volker Kächele, Thomas Seufferlein, Volker Heinemann, Catharina Scholl, Julia Carolin Stingl

Published Apr 24, 2021 · Vol. 12, No. 10 · pp. 982-995

Keywords: miRNA, EGFR, EGFRI, cancer, skin toxicity

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Nathalie Sphyris, Cody King, Jonathan Hoar, Steven J. Werden, Geraldine V. Vijay, Naoyuki Miura, Akhilesh Gaharwar, Tapasree Roy Sarkar

Published Mar 30, 2021 · Vol. 12, No. 8 · pp. 823-844

Keywords: angiogenesis, endothelial transdifferentiation, epithelial-mesenchymal transition, vasculogenic mimicry, FOXC2

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Nathalie Sphyris, Cody King, Jonathan Hoar, Steven J. Werden, Geraldine V. Vijay, Naoyuki Miura, Akhilesh Gaharwar, Tapasree Roy Sarkar

Published Mar 30, 2021

Keywords: angiogenesis, endothelial transdifferentiation, epithelial-mesenchymal transition, vasculogenic mimicry, FOXC2

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Yehia I. Mohamed, Sunyoung Lee, Lianchun Xiao, Manal M. Hassan, Aliya Qayyum, Rikita Hiatia, Roberto Carmagnani Pestana, Abedul Haque, Bhawana George, Asif Rashid, Dan G. Duda, Hesham Elghazaly, Robert A. Wolff, Jeffrey S. Morris, James Yao, Hesham M. Amin, Ahmed O. Kaseb

Published Mar 13, 2021 · Vol. 12, No. 8 · pp. 756-766

Keywords: IGF-1, Child-Pugh, sorafenib, liver reserve, hepatocellular carcinoma

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Duna H. Barakeh, Rasha Aljelaify, Yara Bashawri, Amal Almutairi, Fatimah Alqubaishi, Mohammed Alnamnakani, Latifa Almubarak, Abdulrahman Al Naeem, Fatema Almushawah, May Alrashed, Malak Abedalthagafi

Published Feb 27, 2021 · Vol. 12, No. 7 · pp. 686-697

Keywords: breast cancer, PIK3CA, BCa, Saudi Arabia, BRCA

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment Research Paper

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors Research Paper

Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast Research Paper

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer Review

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab Research Paper

CEA as a blood-based biomarker in anal cancer Research Paper

Association between miRNA signatures in serum samples from epidermal growth factor inhibitor treated patients and skin toxicity Research Paper

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment Research Paper

Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines Research Paper

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients Research Paper

Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors Research Paper

Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast Research Paper

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer Review

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

Multifaceted effect of chlorpromazine in cancer: implications for cancer treatment Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab Research Paper

CEA as a blood-based biomarker in anal cancer Research Paper

Association between miRNA signatures in serum samples from epidermal growth factor inhibitor treated patients and skin toxicity Research Paper

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth Research Paper

Insulin-like growth factor 1/Child-Turcotte-Pugh composite score as a predictor of treatment outcomes in patients with advanced hepatocellular carcinoma treated with sorafenib Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper