The Oncosearch | Oncotarget

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Francesca Punzo, Giulia Bellini, Chiara Tortora, Daniela Di Pinto, Maura Argenziano, Elvira Pota, Alessandra Di Paola, Martina Di Martino, Francesca Rossi

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 687-698

Keywords: macrophage polarization, tumor micro-environment, osteosarcoma, Mifamurtide, MG63

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Pierre Boyé, Franck Floch, François Serres, Zacharie Segaoula, Juliette Hordeaux, Quentin Pascal, Virginie Coste, Sandy Courapied, Emmanuel Bouchaert, Agata Rybicka, Claire Mazuy, Laurent Marescaux, Kévyn Geeraert, Corinne Fournel-Fleury, Alain Duhamel, François Machuron, Pierre Ferré, Aurélie Pétain, Nicolas Guilbaud, Dominique Tierny, Bruno Gomes

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 671-686

Keywords: etoposide phosphate, F14512, non-Hodgkin lymphoma, pet dog model, P-glycoprotein

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Ryan P. Gilley, Peter H. Dube

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 740-754

Keywords: cancer immunotherapy, cancer vaccination, checkpoint blockade, melanoma, listeria

Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions Research Paper

Orly Ben-Nun-Shaul, Rohit Srivastava, Sharona Elgavish, Shashi Gandhi, Yuval Nevo, Hadar Benyamini, Arieh Eden, Ariella Oppenheim

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 574-588

Keywords: sepsis, empty SV40 capsids, RNAseq, signaling, cellular functions

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Manish Charan, Piyush Dravid, Maren Cam, Bhuvana Setty, Ryan D. Roberts, Peter J. Houghton, Hakan Cam

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 510-522

Keywords: pre-metastatic niche formation, osteosarcoma, ANGPTL2, tumor microenvironment, neutrophils

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

Gnoni Antonio, Brunetti Oronzo, Longo Vito, Calabrese Angela, Argentiero Antonel-la, Calbi Roberto, Solimando Antonio Giovanni, Licchetta Antonella

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 480-487

Keywords: antiandrogens, bisphosphonates, bone niche, immune system, osteoimmunology

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. McNulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 216-236

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Xiaochun Wang, Reichelle X. Yeo, Philip J. Hogg, David Goldstein, Philip Crowe, Pierre J. Dilda, Jia-Lin Yang

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 46-61

Keywords: EGFR-targeted therapy, mitochondria inhibitor, tumour metabolism inhibition, sarcomas, combination therapy

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Pharavee Jaiprasart, Samrita Dogra, Deepika Neelakantan, Bharat Devapatla, Sukyung Woo

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 99-114

Keywords: anti-VEGF resistance, angiogenesis, bevacizumab, next-generation sequencing (NGS), apelin

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

Caroline K. Søgaard, Anala Nepal, Voin Petrovic, Animesh Sharma, Nina-Beate Liabakk, Tonje S. Steigedal, Marit Otterlei

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7185-7197

Keywords: APIM, multi-targeting therapy, signaling pathways, autophagy, cancer

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

Shlomit Brodie, Hae Kyung Lee, Wei Jiang, Simona Cazacu, Cunli Xiang, Laila M. Poisson, Indrani Datta, Steve Kalkanis, Doron Ginsberg, Chaya Brodie

Published Dec 11, 2019 · Vol. 12, No. 26 · pp. 2546-2547

Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation Research Paper

Melanie Haas Kucherlapati

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6913-6933

Keywords: proliferation, mutation, transcription, EGFR, lung adenocarcinoma

Survival correlation of immune response in human cancers Research Paper

Yuexin Liu

Published Dec 3, 2019 · Vol. 10, No. 64 · pp. 6885-6897

Keywords: overall survival, progression-free interval, immune response, immunogenicity, cancer

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

Andro Košec, Ruđer Novak, Paško Konjevoda, Vladimir Trkulja, Vladimir Bedeković, Lovorka Grgurević

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6713-6722

Keywords: melanoma, early stage, proteomics, tissue, biomarkers

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

David King, Xiao Dun Li, Gilberto S. Almeida, Colin Kwok, Polly Gravells, Daniel Harrison, Saoirse Burke, Albert Hallsworth, Yann Jamin, Sally George, Simon P. Robinson, Christopher J. Lord, Evon Poon, Daniel Yeomanson, Louis Chesler, Helen E. Bryant

Published Nov 6, 2019 · Vol. 11, No. 23 · pp. 2141-2159

Keywords: PARP inhibitor, neuroblastoma, MYCN, replication stress, replication fork stalling

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Hwudaurw Chen, Earlphia Sells, Ritu Pandey, Edward R. Abril, Chiu-Hsieh Hsu, Robert S. Krouse, Raymond B. Nagle, Georgios Pampalakis, Georgia Sotiropoulou, Natalia A. Ignatenko

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6062-6078

Keywords: colorectal cancer, kallikrein-related peptidase 6 or KLK6, SMAD2/3, epithelial-mesenchymal transition, HMGA2

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Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation Research Paper

Survival correlation of immune response in human cancers Research Paper

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Checkpoint blockade inhibitors enhances the effectiveness of a Listeria monocytogenes-based melanoma vaccine Research Paper

Empty SV40 capsids increase survival of septic rats by eliciting numerous host signaling networks that participate in a number of systemic functions Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy Research Paper

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation Research Paper

Survival correlation of immune response in human cancers Research Paper

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma Priority Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper